• 한국농촌간호학회지
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• 제2권1호
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• pp.33-42
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• 2007

Purpose: This study was done to determine the extent of Clonorchis sinensis infections as well as other parasitic infections and to determine the growth rate. Method: Analyzed test results were from 1,050 bowel samples taken at 3 public health subcenters located in Muju, North Jeolla Province during February and March 2007. Result: The results are summarized as follows; The egg positive rate by stool examination was 4.3%. Ascaris lumbricoides, Enterobius vermicularis, Clonorchis sinensis, Trichuris trichiura, Metagonimus, Paragonimus were detected. No one was infected with multiple parasites. Infection rate for Clonorchis sinensis was 3.5%. Statistical correlation to Clonorchis sinensis infection rate was as follows; Gender (p=0.001), Age (p=0.005), Proximity to a river (p<0.000), Drinking (p<0.000), Smoking (p=0.009), Cooking of freshwater fish (p<0.000), Confidence in subjective health status (p=0.032), Family history of infection (p=0.005), No significant correlation was found between Clonorchis sinensis infection rate and duration of stay (p=0.809) in the agricultural communities or between Clonorchis sinensis infection and knowledge of Clonorchis sinensis (p=0.113). Conclusion: The results of this survey show that there is a need to develop a program to test the condition of Clonorchis Sinensis infection and its growth rate in residents of rural communities.

• 한국농촌간호학회지
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• 제3권1호
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• pp.5-14
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• 2008

Purpose: The purpose of this study was to analyze the trend of research on clonorchis sinensis in Korea. Method: The study design was a literature analysis in which research studies with 'Clonorchis' in the title were collected from 2001 to 2007. A total of 115 research studies were analyzed based on the year of publication, study design, major or institute of researcher, study sample, and research theme. Results: 10-19% of the research studies were published each year from 2001 to 2007. Experimental study design was the most frequent at 54.8%. Medicine or parasitology as the major of researchers were 43.2% and 41.2% retrospectively, but no nursing studies were found. For study samples, 65.9% were cyst larvae and animals, followed by human beings (29.5%). In research theme, the structure and gene analysis of clonorchis sinensis was the most frequent (32.1%), followed by animal experimental studies (15.7%), epidemic studies of clonorchis sinensis prevalence and changes (13.0%), and methods of diagnosis of clonorchis sinensis and effectiveness (12.2%). Conclusion: Although positive rate of clonorchis sinensis is still high, intervention studies for managing clonorchis sinensis were not found. So, methodological research developing clonorchis sinensis management program and intervention study is needed for high risk groups in rural communities.

• 농촌의학ㆍ지역보건
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• 제6권1호
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• pp.61-67
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• 1981

This survey was undertaken to evaluate the status of clonorchiasis in Chang-gok Myun, Hong-Seong Gun adjacent to Yedang reservoir from Sept., 1980 to Oct., 1981. A total of 550 subjects (male 318, and female 232) were examined by cellophane-thick smear technique and formalin-ether method. In order to identify the intensity of the Clonorchis sinensis infection, Stoll's egg dilution counting method was also applied to the C. sinensis positive cases. The following results were obtained in this survey; 1. In the examination of 550 subjects, Clonorchis sinensis eggs were found in 167 cases (30.4%). Male subjects showed 43.4% positive rates and female represented 12.5%. 2. The highest prevalence rate of Clonorchis sinensis was found in 40~49 year group in male (64.2%) and 30~39 year group in female (22.0%), although 14.3%~16.7% positive rates were found in young aged group. 3. Mean E.P.G. of Clonorchis sinensis infected cases were 6,148, showing 7,533 in male and 5,193 in female. 4. The degree of intensity of Clonorchis sinensis infection by E.P.G. count was distributed as 30.4% in light infection (1~999), 45.7% in moderate infection (1,000~29,999) and 5.8% in very heavy infection (over 30,000) in male. Female showed 48.3% in light, 37.9% in moderate, 10.3%. in heavy and 3.5% in very heavy infection. 5. Other helminthic infection rate was 15.6% in Ascaris lumbricoides infection, 15.1% in Trichuris trichiura infection and 4.4% of male subjects showed eggs of Taenia species.

• 농촌의학ㆍ지역보건
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• 제7권1호
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• pp.43-49
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• 1982

Clonorchiasis sinensis is one of the most important endemic diseases in Korea, and this disease has been known to be one of public health concern in many areas of Korea. This survey was undertaken to evaluate the status of clonorchiasis in Yeoju Gun, Gyeong-gi Do from July to September 1980. A total of 1,194 male students were examined by intradermal test with Clonorchis antigen. In order to detect Clonorchis egg, the stool examinations were undertaken to 1,158 students, and the intensity of the Clonorchis infection was estimated by the Stoll's egg count. The prevalence rate was reanalyzed by the regional groups for an investigation of regional characteristics of infection. The following results were obtained in this survey. 1) Among 1,194 students in Yeoju Eup, positive rate of intradermal test with C. sinensis antigen was 17.2 percent. (middle school14.6% and high school 20.1%). 2) In the examination of 1,158 stool specimens, Clonorchis eggs were found in 97 (8.4%) cases. 3) Mean E.P.G. of Clonorchis infected case was $1,330{\pm}2,620$. 4) The degree of the intensity of Clonorchis infection by E.P.G. count was distributed as 73.6% in light infection (100-999), 22.6%, in moderate infection (1,000-9,999), and 3.8% in heavy infection (10,000-29,999). 5) High prevalence rate of Clonorchis sinensis was found in the Sang-Ri(9,3%) and Ha-Ri(8.4%) in Yeoju Eup. Neighbouring Bugnae Myun (11.5%), Gangcheon Myun(12.1%) and Neungseo Myun (11.1%) adjacent to the river had a similary high prevalence of C. sinensis.

• Archives of Pharmacal Research
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• 제21권6호
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• pp.744-748
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• 1998

Several praziquantel derivatives have been prepared by the acylation of compound 5, and examined on their biological activity in vitro agninst adult clonorchis sinensis collected from rabbits infected with metacercariae which was isolated from Pseudorasbora parva, a second intermediate host, captured in Nakdong river in Korea.

• Parasites, Hosts and Diseases
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• 제40권4호
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• pp.173-176
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• 2002

Glutathione S-transferase (28GST) with molecular mass of 28 kDa is an anti-oxidant enzyme abundant in Clonorchis sinensis. In adult C. sinensis, 28GST was localized in tegumental syncytium, cytons, parenchyma, and sperm tails examined by immunoelectron microscopy. C. sinensis 28GST was earlier found to neutralize bio-reactive compounds and to be rich in eggs. Accordingly. it is suggested that 28GST plays important roles in phase II defense system and physiological roles in worm fecundity of C. sinensis.

• 대한수의사회지
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• 제10권2호
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• pp.8-9
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• 1966

• 지역사회간호학회지
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• 제22권1호
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• pp.56-65
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• 2011

Purpose: The goal of this study was to analyze the prevalence of Clonorchis sinensis infection in people living within 5 km of the Youngsan River basin, to develop an educational program to prevent the infection, and to examine the effects of the educational program. Methods: This study employed a one group pretest-posttest design, the subjects were 384. This study was conducted from November 20, 2008 to June 16, 2009. The results were analyzed with the SPSS/WIN 18.0 program. Results: Of the residents, 5.7% were infected with Clonorchis sinensis and the knowledge level about the prevention of Clonorchis sinensis was improved significantly from $9.57{\pm}5.12$ points before the education to $15.05{\pm}2.43$ points after the education. One of the important effects was that the willingness to eat raw fresh-water fish was reduced after the education. Conclusion: Based on the results of this study, a continuous research needs to be conducted on how education and knowledge level-up change people's living attitudes for the prevention of Clonorchis sinensis infection and the reduction of the infection rate in the future.

• Parasites, Hosts and Diseases
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• 제32권4호
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• pp.207-214
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• 1994

대청댐 상류 금강유역, 옥천 금산, 무주지역 주민의 장내 기생충과 간흡충란을 조사하기 위하여 1991년 1월부터 10월까지 743명의 대변 검사를 셀로판후층도말법과 formalin-ether원 심침전법으로 실시하였던 바 그 결과를 요약하면 다음과 같다. 연충란 및 원충시스트 총양성률은 40.8%(연충 8종. 원충 5종)이었다 각 종별 양성률은 간흡충 30.8%. Metanonim종 14.5%, Fosiola종 0.7%, Toenia종 1.5%, 회충 0.4%, 요충 0.l%, 구충 0.1%, 편충 1.6%, 대장아메바 0.7%. 이질아메바, 왜소아메바, 람블편모충이 각각 0.3%와 요드아메바 0.1%이었다 지역별 총양성률은 충청북도 옥천이 51.1%로 가장 높았고 괴음이 충청남도 금산이 50.8%이었으며 전라 북도 무주는 3개 군지역 중에서 비교적 낮은 양성률(28.6%)을 보였다. 금강 중.상류 지역에서는 간흡충과 Metagonimus종이 아직도 높은 양성률을 보이고 있으며 Taenia종도 크게 감소되지 않았으나 토양 매개성 장내 기생연충과 원충은 대단히 많은 감소를 보였다.

• 한국농촌간호학회지
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• 제4권1호
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• pp.13-21
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• 2009

Purpose: This study was done to investigate the prevalence and related factors of Clonorchis Sinensis for inhabitants of the Han riverside area and to identify knowledge related to Clonorchis Sinensis and intended behavioral changes to decrease risk of infection. Method: The data were collected from December 16, 2008 to January 10, 2009. Participants were 555 people who responded to a questionnaire. Frequency, percentage, $X^2$-test, and t-test were used to analyze the data. Results: The prevalence of Clonorchis Sinensis was 7.9% in this population. Related factors for Clonorchis Sinensis were gender (male=10.8%, female=3.6%, p=0.002) and smoking (p=0.007). but habits related to ingestion of alcohol and raw fish were not significant. As for knowledge of Clonorchis Sinensis, the Clonorchiasis group had a mean score of 10.09 $({\pm}3.95)$ of a possible 17 compared to a score of only 8.27$({\pm}4.60)$ for the negative group (p=0.011). The intended behavioral change related to risk of infection, according to presence of infection or not, was significant (p=0.004). Conclusion: These results suggest that Clonorchiasis is still highly endemic in all risk areas such as the Han riverside, indicating that it is necessary to set up effective management programs for patient care and prevention of Clonorchis Sinensis.