• 제목/요약/키워드: Clinical type

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Effect of coadministration of enriched Korean Red Ginseng (Panax ginseng) and American ginseng (Panax quinquefolius L) on cardiometabolic outcomes in type-2 diabetes: A randomized controlled trial

  • Jovanovski, Elena;Smircic-Duvnjak, Lea;Komishon, Allison;Au-Yeung, Fei (Rodney);Sievenpiper, John L.;Zurbau, Andreea;Jenkins, Alexandra L.;Sung, Mi-Kyung;Josse, Robert;Li, Dandan;Vuksan, Vladimir
    • Journal of Ginseng Research
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    • 제45권5호
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    • pp.546-554
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    • 2021
  • Background: Diabetes mellitus and hypertension often occur together, amplifying cardiovascular disease (CVD) risk and emphasizing the need for a multitargeted treatment approach. American ginseng (AG) and Korean Red Ginseng (KRG) species could improve glycemic control via complementary mechanisms. Additionally, a KRG-inherent component, ginsenoside Rg3, may moderate blood pressure (BP). Our objective was to investigate the therapeutic potential of coadministration of Rg3-enriched Korean Red Ginseng (Rg3-KRG) and AG, added to standard of care therapy, in the management of hypertension and cardiometabolic risk factors in type-2 diabetes. Methods: Within a randomized controlled, parallel design of 80 participants with type-2 diabetes (HbA1c: 6.5-8%) and hypertension (systolic BP: 140-160 mmHg or treated), supplementation with either 2.25 g/day of combined Rg3-KRG + AG or wheat-bran control was assessed over a 12-wk intervention period. The primary endpoint was ambulatory 24-h systolic BP. Additional endpoints included further hemodynamic assessment, glycemic control, plasma lipids and safety monitoring. Results: Combined ginseng intervention generated a mean ± SE decrease in primary endpoint of 24-h systolic BP (-3.98 ± 2.0 mmHg, p = 0.04). Additionally, there was a greater reduction in HbA1c (-0.35 ± 0.1% [-3.8 ± 1.1 mmol/mol], p = 0.02), and change in blood lipids: total cholesterol (-0.50 ± 0.2 mmol/l, p = 0.01), non-HDL-C (-0.54 ± 0.2 mmol/l, p = 0.01), triglycerides (-0.40 ± 0.2 mmol/l, p = 0.02) and LDL-C (-0.35 ± 0.2 mmol/l, p = 0.06) at 12 wks, relative to control. No adverse safety outcomes were observed. Conclusion: Coadministration of Rg3-KRG + AG is an effective addon for improving BP along with attaining favorable cardiometabolic outcomes in individuals with type 2 diabetes. Ginseng derivatives may offer clinical utility when included in the polypharmacy and lifestyle treatment of diabetes. Clinical trial registration: Clinicaltrials.gov identifier, NCT01578837;

해리성대동맥류 58례에 대한 임상적 고찰 (Clinical Analysis of 58 Cases of Aortic Dissecting Aneurysm)

  • 정철하
    • Journal of Chest Surgery
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    • 제27권1호
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    • pp.31-35
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    • 1994
  • Dissecting aortic aneurysm is a life threatening condition which necessitates prompt diagnosis and management. Between January 1987 and September 1993,58 patients was admitted to our department. Mean age at admission was 53 years.[range 25-82]. Clinical findings included chest pain in 48 cases[83%],renal failure in 12[20%],aortic insufficiency in 11[19%] and stroke in 9[15%]. Predisposing factors were hypertension in 50 cases[86%],Marfan`s syndrome in 6[10%] and diabetes melitus in 1 [2%]. 23 patients[ type A 13,type B 10 ] underwent surgical treatment. Surgical technique for type A included graft replacement of ascending aorta in 7 cases,graft replacement and aortic valve resuspension in 3,and Bentall`s operation in 3 cases. Type B patients were operated when specific indications applied. There were three [Two in type A and 1 in type B] deaths in the operation group and nine [ 5 in type A and 4 in type B] deaths in the medical group. These results support our current policy in the treatment of dissecting aortic aneurysm.

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에니어그램 힘의중심에 따른 간호대학생의 간호역량, 임상추론역량 및 공감능력의 관계 (Relationship between Nursing Students' Nursing Competency, Clinical Reasoning Competence and Empathy Ability according to the Enneagram Center of Power)

  • 신은선
    • 문화기술의 융합
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    • 제10권2호
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    • pp.373-382
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    • 2024
  • 본 연구는 간호대학생에게 에니어그램 힘의중심에 따른 간호역량, 임상추론역량 및 공감능력의 관계를 파악하고자 시도되었다. 연구의 대상자는 일 지역에 소재하는 2개 대학의 간호학과에 재학중인 학생으로 218명이었으며, 자료수집은 2023년 10월 16일부터 10월 27일까지 실시되었다. 자료분석은 SPSS/WIN version 26.0 프로그램을 활용하여 기술통계, 차이검증은 t-test, ANOVA, pearson's correlation coefficient으로 분석하였다. 연구결과, 본 연구대상자의 에니어그램 성격유형은 9번 유형이 가장 많았다. 그리고 에니어그램 힘의중심에서는 본능중심형이 간호역량이 가장 높았고, 사고중심형은 임상추론역량이 가장 높았으며, 감정중심형은 공감능력이 가장 높았다. 또한 간호역량과 임상추론역량은 유의한 양의 상관관계를 보였고, 임상추론역량과 공감능력도 유의한 양의 상관관계가 있는 것으로 나타났다. 따라서 간호대학생에게 성격유형검사를 반영한 개인에게 맞는 역량강화프로그램을 지속적으로 개발하여 적용하는 것이 중요할 것으로 생각된다. 그리고 공감능력이 높을수록 임상추론역량이 높아 간호역량과 임상추론역량을 향상시킬 수 있는 표준화된 교육과정을 개발하고 그 효과를 검증하는 것이 필요할 것으로 생각된다.

임상실습 초기와 종료 후의 임상실습에 대안 간호학생의 인식 변화 (Changes in Student Nurses' Perception between Initial and Final Clinical Practice)

  • 김명애;남승희;김효은
    • 기본간호학회지
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    • 제11권1호
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    • pp.21-30
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    • 2004
  • Purpose: The purpose of this study was to explore perception of clinical experience between the initial and final practice and to explore changes in the perception of clinical experience. Method: The study used a Q-method to measure perception of clinical practice. Thirty-six statements made up the finalized Q-sample. The P sample used thirty three nursing college students from K university. The initial collection was done in the first semester of their junior year and second collection was done in the last semester of their senior year. The Q-sorts by each student were coded and analysed with the Quanl PC program. Result: Many students classified as having the perception type 'alienation of ideal and reality' or 'perception of limitation of ability' in the initial clinical practice changed to the type, 'active participation' by the final clinical practice. Further, in the initial clinical practice, part of 'active participation' and 'perception of limitation of ability' changed to 'alienation of ideal and reality'. Conclusion: This study shows that perception of their clinical practice by student nurses changed in a positive direction through clinical experience and that this fact was related to the level of satisfaction with nursing. The knowledge and understanding obtained in this research provide insights for nursing faculty and students involved in nursing education.

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삼출성 중이염에 대한 임상적 고찰 (A Clinical Study of Otitis Media with Effusion in the Oriental Medicine.)

  • 김윤범;채병윤
    • 한방안이비인후피부과학회지
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    • 제5권1호
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    • pp.133-142
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    • 1992
  • We analyzed clinical study in 47 patients, who had visited to the Dept. of Otolaryngology, Hospital of Oriental Medicine, Kyung Hee University to treat Otitis media with effesion from March, 1991 to February, 1992. The clinical etiology of O.M.E. was tubal occlusion, acute otitis, and allergy. The clinical symptoms were hearing loss, tinnitus, sneezing, coughing, Chun-I(纏耳), and BEE-Yeon(鼻淵) in the Oriental Medicine. The results were as follows. 1. There were 26 males ($55\%$) and 21 females ($45\%$) in sex. 2. The peak age at onset was 1-4 years old (11Cases). 3. Bilateral effusion was in $62\%$, and unilateral in $38\%$. 4. The etioloigic factors were upper respiratory infection 16 cases, Allergic rhinitis 13 cases, Sinusitis 8 cases, etc. 5. The most common chief complaint was hearing loss ($30\%$). 6. There was no significant difference between blood types in O.M.E., ( A type $30\%,\;B\;type\;25\%,\;AB\;type\;13\%,\;0\;type\;13\%$, Unknown recorded $9\%$ ). 7. $21\%$ patients prefered warm and the others cold 8. As for digestion, good was in 31 cases ($81\%$), and poor 9 cases ($19\%$). 9. Man-Hyung-Ja-San Extract was most used in treatments as $38\%$, O-Ryung-San $35\%$ in descending order. 10. As for treatment period, 14 cases were treated over 12 weeks, 9 cases below 1 week

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Diagnostic Hierarchy of Tic Disorders in Real-World Clinical Practice

  • Yeeji Sung;Soon-Beom Hong
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제34권4호
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    • pp.236-241
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    • 2023
  • Objectives: According to the 10th revision of the International Classification of Diseases, the main categories of tic disorders (F95.0, F95.1, and F95.2) follow a diagnostic hierarchy based on the duration and diversity of tic symptoms. The present study investigated the use of this diagnostic hierarchy in real-world clinical practice. Methods: Based on the National Health Insurance Service-National Health Information Database, the diagnosis of transient tic disorder (F95.0) made after a diagnosis of chronic motor or vocal tic disorder (F95.1) or Tourette's syndrome (F95.2) and diagnosis of chronic motor or vocal tic disorder (F95.1) made after a diagnosis of Tourette's syndrome (F95.2) were referred to as type A errors. The diagnosis of transient tic disorder (F95.0) repeated after a period of >12 months was referred to as type B error. Demographic and clinical differences according to the diagnostic error types were analyzed using analysis of variance, Student's t-tests, and chi-squared tests. Results: Most participants (96.5%) were without errors in the diagnosis of tic disorders. Higher proportions of males (p=0.005) and antipsychotic prescriptions (p<0.001) were observed in patients with type A or B diagnostic errors. A higher proportion of health insurance holders was observed among those with type A errors (p=0.027). Conclusion: Errors were absent in majority of the tic diagnoses in real-world clinical practice in terms of the diagnostic hierarchy.

견비통 환자의 경락 유형별 침구 치료에 대한 임상적 고찰 (Clinical Study about Acupuncture and Moxibustion Treatment according to the different type of the Meridian Pathways of the Patients who have Shoulder Pain)

  • 이희윤;김상헌;허정은;윤현민;김원일
    • Korean Journal of Acupuncture
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    • 제23권4호
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    • pp.67-84
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    • 2006
  • Objectives : This clinical trial is to know how significant the acupuncture treatments are which were done on appropriate acupuncture-points with using method of classification by meridian pathways along the parts of the shoulder pain. Methods : 27 shoulder pain patients who participated in the clinical study in the Bukpyeoung haemalkeun oriental medical clinic which is located in Donghae city were classified 3 types(Yangmyeng, Soyang, Taeyang meridian type) according to their different parts of the shoulder pain. They have been acupunctured in their applied acupoints in the body 3 times a week for 4 weeks. Results : After 4 weeks of the treatments, there were statistically meaningful treatment effect in all index in Yangmyeng meridian type. In Soyang meridian type, there were statistically meaningful treatment effect in 'subjective symptom of shoulder pain','shoulder pain and disability index', 'visual analog scale'. In Taeyang meridian type, statistically effective treatment result was found in 'shoulder pain and disability index' Conclusions : Every type has statistically meaningful treatment effects according to the analysis of the results.

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윤리풍토가 일부 임상치과위생사 직무만족에 미치는 영향 (Effects of Ethical Climate on Job Satisfaction of Clinical Dental Hygienists)

  • 천석연;황창주
    • 한국치위생학회지
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    • 제18권4호
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    • pp.515-524
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    • 2018
  • Objectives: The purpose of this study is to investigate whether the ethical climate affects the job satisfaction of the clinical dental hygienists. Methods: A self-reported questionnaire was filled out by 207 dental hygienists. The data were analyzed by t-test or one-way ANOVA, multiple regression analysis, and Pearson's correlation analysis using IBM SPSS Statistics 19.0 program. Results: The factors affecting the job satisfaction of the general and ethical climate were the work experiences, the completion of vocational ethics education, the self interest type, the friendship type, the rule and the procedure type. When working experience and vocational ethics education are completed, self interest type and friend type have improved job satisfaction as the score increases, while job satisfaction is lowered as the rule and procedure type are increased. Conclusions: Since healthy ethical climate correlates with job satisfaction, it is necessary to establish an ethical climate in order to improve the job satisfaction of clinical dental hygienists. Efficient and stable management of ethical climate within dental clinics can be achieved when mutual interests are emphasized and respected rather than obedience is empathized to hospital regulations, procedures and policies.