• 제목/요약/키워드: Clinical symptoms and signs

검색결과 788건 처리시간 0.031초

Delayed Clinical Signs Associated with Cerebellar Lesion in Holstein Calf Infected with Bovine Viral Diarrhea Virus

  • Choi, Woojae;Ro, Younghye;Hong, Leegon;Kim, Eunkyung;Choe, Eunhui;Kim, Danil
    • 한국임상수의학회지
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    • 제39권1호
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    • pp.38-43
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    • 2022
  • A 5-month-old Holstein downer calf was presented, and bovine viral diarrhea virus was detected in the feces and the cerebrospinal fluid. Combined treatment of recombinant bovine somatotropin (rBST) administration and standing rehabilitation had been performed for two months, and the calf could maintain the standing position for a while. However, the symptoms were not improved, and the calf died due to ruminal tympany and aspiration pneumonia. Megaesophagus, abomasal ulcer, and a normal-sized but softened cerebellum were observed in clinical necropsy. Improvement of symptoms was confirmed by rBST, but was not reached the complete recovery of gait and standing position.

폐암의 임상적 고찰 (Clinical Evaluation of the Lung Cancer)

  • 최순호
    • Journal of Chest Surgery
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    • 제11권1호
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    • pp.26-34
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    • 1978
  • We observed 82 cases of primary lung cancer clinically and statistically, which had been experienced at the dept. of thoracic surgery, Chonnam University Hospital, during the period of 13 years from 1964 to 1967. The results obtained were as follows: Peak incidence of age was from 5th decade to 6th decade, and the ratio of male to female was 3: 1. The frequency of lung cancer was higher in the heavy smoker than in the lighter smoker, and undifferentiated carcinoma showed low resectability in spite of the shorter clinical duration. Major symptoms were coughing and chest tightness & pain, especially coughing was initial symptom in the majority of patients. Of the 82 cases, operation was performed in the 32 cases [39%], but resection was possible in the 22 cases [27%]. The delaying factors led patients to an inoperable stage were physician’s misdiagnosis of bronchogenic carcinoma due to non-specific symptoms and signs of the patients, old age patients were dependence on herb medicine, and poor economical condition of the patients in our region especially. Basic conditions of treatment in lung cancer were early detection & early surgery, so, chest P-A would be checked per 3 to 6 months interval associated with sputum cytology in the smoker over 45 age routinely.

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Hematopoietic Cell Transplantation in Patients with Mucopolysaccharidosis Type II

  • Song, Ari
    • Journal of mucopolysaccharidosis and rare diseases
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    • 제5권1호
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    • pp.12-16
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    • 2021
  • Mucopolysaccharidosis type II (MPS II, Hunter syndrome) is an X-linked lysosomal storage disorder caused by deficiency of the enzyme iduronate-2-sulfatase, leading to the accumulation of glycosaminoglycans (GAGs), which affects multiple organs and systems. Current treatments for MPS II include enzyme replacement therapy (ERT) and hematopoietic cell transplantation (HCT) to reduce the accumulation of GAGs. HCT has the potential advantage that donor-derived enzyme-competent cells can provide a continuous secreting source of the enzyme. However, HCT as a treatment for MPS II remains controversial because its effectiveness is unclear, particularly in terms of neurological symptoms. To date, several clinical experiences with HCT in MPS II have been reported. In this paper, we review post-HCT outcomes in the previously published literature and discuss the effects of HCT on each of the clinical signs and symptoms of MPS II.

A Case of Cyclosporine Treatment in Cat with Allergic Dermatitis, Nonresponsive to Prednisolone Treatment

  • Ryu, Dongwook;Kang, Jooyeon;Ko, Minho;Cho, Hyunkee;Han, Jeong-Hee;Chung, Jin-Young
    • 한국임상수의학회지
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    • 제33권6호
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    • pp.392-394
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    • 2016
  • A 2-year-old spayed female Persian cat presented to Kangwon National University Veterinary Medical Teaching Hospital with pruritus and erythema on the tips of both ears, around the eyes, and in the caudal abdomen. This patient had previously been prescribed prednisolone, but did not respond positively to the treatment. A skin screening test revealed that there were no fleas or fungi, and that only cocci were present. Blood testing revealed no remarkable findings. The patient was prescribed antibiotics (amoxicillin-clavulanic acid 25 mg/kg for 2 weeks) with no prednisolone. After 2 weeks, clinical signs were alleviated and the skin screening test showed no signs of cocci. However, clinical signs recurred even with the prescription of antibiotics. Four weeks after the steroid-free interval, Malassezia spp. hypersensitivity was detected upon a serum allergy test, and pathological analysis confirmed eosinophilic and mastocytic superficial dermatitis in the caudal abdomen. Based on these results, we suspected allergic dermatitis and prescribed 7 mg/kg cyclosporine A once a day. After 3 weeks, clinical signs were resolved. Seven weeks after the first trial with cyclosporine A, we reduced the cyclosporine A dose to 7 mg/kg every other day. The patient's symptoms have since been well controlled for 6 months. This study suggests that cyclosporine A can be a good choice for treating cats with suspected allergic dermatitis that has not responded positively to steroid treatment.

소청룡탕(小靑龍湯)을 이용한 한포진(汗疱疹) 치험 1례 (A Clinical Study about the Effect of Socheongryong-Tang on a Dyshidrotic Eczema Patient)

  • 강나루;탁명림;고우신;윤화정
    • 한방안이비인후피부과학회지
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    • 제24권1호
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    • pp.192-199
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    • 2011
  • Objectives : The purpose of this study is to know the effect of Socheongryong-Tang on Dyshidrotic Eczema. Methods : We experienced one case of Dyshidrotic Eczema treated with Socheongryong-Tang. We have diagnosed the patient through the abdominal examination and have decided the treatment principle accordingly. We used visual analogue scale(VAS). Results : After the treatment the grade of VAS was decreased and clinical symptoms were gradually disappeared. Conclusion : Socheongryong-Tang have improved the signs and symptoms of Dyshidrotic Eczema case. It is concluded that Socheongryong-Tang is considerably effective on the treatment of skin disease that is related to rhinitis.

Invasion of the canalis sinuosus by dental implants: A report of 3 cases

  • Shintaku, Werner Harumiti;Ferreira, Cimara Fortes;Venturin, Jaqueline de Souza
    • Imaging Science in Dentistry
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    • 제50권4호
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    • pp.353-357
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    • 2020
  • The canalis sinuosus (CS) and its accessory canals (ACs) are anatomical structures in the anterior maxilla. These structures are often neglected when planning implant surgery because their clinical significance is still not well-defined. After a retrospective evaluation of 194 patients rehabilitated with dental implants in the anterior maxilla, 3 patients were identified who presented unexpected chronic neurosensory disturbances without any clinical signs supportive of implant failure. Tomographic assessment using cone-beam computed tomography (CBCT) revealed the invasion of the CS and ACs by dental implants, which appeared to explain the patients' symptoms. The purpose of this report was to familiarize practicing dentists and specialists with the CS and its ACs. Unanticipated neurosensory symptoms after implant placement in the anterior maxilla justify the use of CBCT to rule out an injury to this neurovascular bundle.

Comparison between SNAP Canine Pancreas-Specific Lipase (cPL) Test Results and Pancreatic Ultrasonographic Findings in Dogs with Pancreatitis

  • Kim, Myung-Jin;Song, Joong-Hyun;Hwang, Tae-Sung;Lee, Hee-Chun;Jung, Dong-In
    • 한국임상수의학회지
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    • 제34권4호
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    • pp.229-233
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    • 2017
  • The object of the present study was to compare abnormal serum canine pancreas-specific lipase results and pancreatic ultrasonographic findings in dogs with pancreatitis. Pancreatitis is a common disease in dogs that is difficult to diagnose. The noninvasive diagnostic procedures, including a serum canine pancreatic-specific lipase (cPL) test and ultrasonographic changes in the pancreas, can be considered for the diagnosis of canine pancreatitis in clinical practice. A retrospective study was performed to assess pancreatitis in dogs. Forty client-owned dogs were suspected to have pancreatitis, which was confirmed by abnormal serum SNAP cPL results. Abdominal ultrasound examinations were also performed. The present study investigated the distribution of clinical signs associated with pancreatitis, and the dogs were divided into two groups: group 1 (clinical signs compatible with pancreatitis; n = 30) and group 2 (no clinical signs; n = 10). Based on this study, an abnormal result on the SNAP cPL assay can still present as a normal pancreas through an ultrasonographic examination, and a normal health status can identify the status of pancreatic ultrasonographic abnormal lesions. Therefore, for dogs with suspected pancreatitis, it is important to repeat an ultrasonographic evaluation. There is no significant difference between clinical symptoms and ultrasonographic changes in the pancreas.

Tectal glioma presenting with adult-onset epileptic seizures

  • Kim, Jin Hee;Jo, Hyunjin;Choi, Jung Won;Joo, Eun Yeon
    • Annals of Clinical Neurophysiology
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    • 제23권1호
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    • pp.56-60
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    • 2021
  • Tectal glioma is an indolent and benign tumor that occurs predominantly in the pediatric population. It arises in the tectum of the midbrain and, due to its location, contributes to the development of obstructive hydrocephalus, typically presenting with increased intracranial pressure (IICP) symptoms or signs. Here we report a rare case of tectal glioma that presented as adult-onset epileptic seizures without IICP symptoms and was treated with endoscopic third ventriculostomy and antiepileptic drugs.

백신접종 방법에 따른 뉴캣슬병 $B_1$생독백신의 효능비교 (Comparison of Efficacy of Newcastle Disease Virus $B_1$ Vaccine by Different Administration .Methods in Commercial Layer Chickens)

  • 정만호;최정옥;강춘원;노용기
    • 한국가금학회지
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    • 제17권3호
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    • pp.225-232
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    • 1990
  • 실용 산란계 병아리에 대해서 시중에서 유통되고 있는 B$_1$생독 뉴캣슬병백신의 효능을 접종방법과 접종횟수를 달리하여 비교하였다. 실용산란계 372수를 93수씩 4군으로 나눈 후 3군에 대해서는 각각 음수. 점안, 분무방법으로 28일령까지 3회에 걸쳐 백신을 접종하였고 나머지 1군은 백신을 접종하지 않은 대조군으로 하였다. 매회 백신접종 2준 4주 후에 강독 바이러스로 공격접종하여 방어율을 조사하고 2주 간격으로 채혈하여, 혈구응집억제(HI) 항체가를 조차하였다. 방어율은 1일령에 1회 접종하는 것보다 2회 또는 3회 접종하는 것이 높았으나 2회. 3회간에는 큰 차이가 없었다. 접종방법간에는 분무방법이 2회 이상 접종할 경우 방어율이 높았으며 다음은 점안, 음수 순이었다. 백신을 2회 또는 3회 접종하여도 HI항체가는 대조군에 비해 크게 상승하지 않았다. 전반적으로 방어율이 낮은 것은 백신의 역가가 낮기 때문으로 생각되었다. 공격접종 후 뉴캣슬병 임상증상은 84% 이상에서 원기 및 식욕저하와 기면을 보였고 27%에서 설사, 15%에서 호홉곤란, 10%에서는 사경을 보였다. 부견소견상 출혈반은 십이지장(51%), 기관(36%), 회장(13%), 맹장편도(11%), 선위(10%) 순으로 관찰되었다.

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사르코이드증에 동반된 다발신경병증 (Sensorimotor Polyneuropathy Associated with Sarcoidosis)

  • 안석원;김동욱;홍윤호;이광우
    • Annals of Clinical Neurophysiology
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    • 제5권1호
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    • pp.39-41
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    • 2003
  • Sarcoidosis is a multisystemic granulomatous disease of unknown etiology ogenesis, and most frequently presented with bilateral hilar lymphadenopathy, pulmonary infiltration, skin and eye lesion. However, neurological involvement including peripheral neuropathy is relatively rare. We report a patient who had sensorimotor polyneuropathy without other systemic symptoms or organ involvements frequently reported in sarcoidosis. Laboratory investigation suggestive of sarcoidosis lead to sural nerve biopsy for confirmation, which demonstrated noncaseating granulomatous changes. Sarcoidosis shoud be included in the differential diagnosis in subacute polyneuropathy even if there is no usual symptoms or signs suggestive of the systemic disease.

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