• 대한간호
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• 제13권2호통권70호
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• pp.80-81
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• 1974

• 한국동물위생학회지
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• 제19권1호
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• pp.1-29
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• 1996

This study was conducted to elucidate the pathogenesis of Aujeszky's disease virus(ADV) by histopathologic examination. The first Korean ADV Isolate, which was isolated from piglets with clinical signs of Aujeszky's disease in Yangsan(YS) county, Kyungnam province, was inoculated into 32 days old piglets with a dose of $10^{5.9}$$TCID_{50}/ml$ through intranasal or intramuscular route. These piglets were sacrificed at intervals of every 24hrs for 8 days. The virulence of YS strain was determined by the observation of clinical signs, gross findings, and histopathologic changes in tissues. The virus recovery test was performed from brain, spleen, lung and tonsil in cell culture. The pathogenesis of YS strain was determined by the observation of histopathologlc lesions in CNS and neuronal tracts. The major clinical signs were fever, anorexia, dyspnea, constipation, tremor, ataxia, circling movement, hindleg paralysis and salivation. The clinical signs were more severe in piglets of the group inoculated intranasally than those of the intramuscularly inoculated gorup. Lymphocytopenia was detected on day 5 to day 6 postinoculation (PI). The ADV was recovered from the tissue homogenates of tonsil, lung, spleen and cerebrum in cell culture. The highest virus titer was detected from tonsil between day 6 and day 7 PI. Reddish sublobar consolidation foci were scattered in the apical and cardiac lobes of lung. Although yellowish necrotic foci were detected in tonsil and liver, hemorrhagic lesions were mainly observed in heart, kidney and lymph nodes. Histopathologically, degeneration and necrosis of nerve cells, nonsuppurative meningoe-ncephalitis, nodular gliosis and perivascular cuffings were observed in CNS. Multifocal fibronecrotic foci were observed in lung, liver, lymph nodes and spleen. The major pathologic changes were detected in the midbrain, pons and medulla oblongata. Eosinophilic intranuclear inclusion bodies were mainly observed in epithelia and /or macrophages of tonsil, liver, lung, spleen and submandibular lymph nodes, and neurons of brain, respectively. Observation of viral particles at various stages of replication were possible from the endothelial cells of the alveolar capillaries and tonsillar crypt epithelia by transmission electron microscope.

• 대한임상전기생리학회지
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• 제9권1호
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• pp.15-21
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• 2011

Purpose : This study aims to examine the effects of action observation of ski simulation on electroencephalogram (EEG). Methods : Thirty healthy subjects were randomly divided into three groups: 10 participants in an AM (actual movement) group; 10 participants in an OM (observation) group; and 10 participants in a CM (control movement) group. The EEG was measured to examine changes in EEG between action observation and actually movement at 8 areas of the scalp for one minute before, during and after action observation. Results : Relative alpha power showed statistically significant differences among groups in Cz and C4 and there were interactions among groups in the Oz area. Relative beta power showed no statistical significance among groups and in particular, there were interactions among groups in the Oz area. Conclusion : These findings show that action observation affected brain activation as in actual movement. Thus it can be expected that when movement through the brain activation is applied to patients in bed rest or those who cannot perform actually movement, it can be utilized as physiotherapy.

• 대한물리치료과학회지
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• 제27권1호
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• pp.18-25
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• 2020

Purpose: The purpose of this study was to investigate the improve on brain activity during action observation training for cerebral palsy of diplegia. Design: Randomized controlled trial. Methods: 18 subjects were divide into two groups: action observation training group and a control group. Action observation group practiced repeatedly the action with their motor skill and control group practiced conventional physical therapy. The subjects participated in eighteen 30-min sessions, 3 day a week, for 6week. To confirm the effects on brain activity were evaluated. Results: The results show that the Mu-rhythm was statistically significant increase on the C3 of the action observation training group (p<0.05). Conclusion: The action observation training improves brain activity of a cerebral palsy with diplegia. These results suggest that the action observation training is feasible and beneficial for improving brain activation for the cerebral palsy with diplegia. In the future, I think we need to be actively utilized to the action observation training program in the clinical with the neuromuscular development treatment. And the study on the various the action observation training program that can improve the function of the children with cerebral palsy is thought necessary.

• 간호행정학회지
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• 제8권2호
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• pp.273-281
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• 2002

Purpose. The study was done to develop nursing guidelines to prevent nursing negligence in the clinical setting that would lead to malpractice. Method. A comprehensive review of the literature and focus groups interviews were used to search for malpractice cases related to "observation", one of the most basic nursing activities. The cases were analyzed with respect to nursing practice and a legal expert was consulted on the content. Results. 4 malpractice cases related to observation negligence were selected for this study; 1) a case of failing to observe dyspnea after a thyroidectomy, 2) a case of failing to observe a depressed patient for suicide attempts, 3) a case of failing to observe a VP shunt obstruction, 4) a case of failing to observe a cardiac ischemia after a bronchoscopy. 11 guidelines were developed for clinical nurses and 13 guidelines for nursing managers. Conclusion. These guidelines are useful in preventing malpractice due to nursing negligence. Therefore nurses need to apply them to their practices and continue to make an effort to develop guidelines for other malpractice situations.

• Korean Journal of Acupuncture
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• 제23권4호
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• pp.101-110
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• 2006

Objectives : The purpose of this study was clinical observation about sensorineural hearing loss compare with acupucture treatment and assessments of prognotic factors. Methods : This study was clinical observation about sensorineural hearing loss cases. for diagnosing in these cases, pure tone audiometry was used. The treatment, acupuncture was used. Results : Three patients(37.5%) remarkably improved, one patient(12.5%), slightly improved, four patients(50%), no change. Conclusions : These results suggest that the prognosis by age and initial hearing threshold was significant. The treatment on sensorineural hearing loss considered that bone condution improved.

• Clinical and Experimental Reproductive Medicine
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• 제4권1호
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• pp.33-39
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• 1977

During the last 10 years 8 months, clinical observation has been done on 43 cases of cryptorchisms. 1. The cryptorchism has relatively high incidence rate among the anomalies of genitourinary tract(27.2%). 2. The age group, most frequently seen, was between 6 to 10 and the average age visited the hospital at the first time is 11.4 years. It means 4 to 6 years later than age for the adequate treatment required. 3. Atrophy of the seminiferous tubules, interstitial fibrosis and poor or absent spermatogenesis were noted on the 8 cases of cryptorchid biopsies. 4. Hormonal therapy(Puberogen) was done on 16 cases and 8 cases were responded. But there was no complete descent of testis through this hormonal therapy.

• Communications for Statistical Applications and Methods
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• 제15권3호
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• pp.353-365
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• 2008

임상시험에서 피험자수는 검정가설, 변수값의 분산과 유효차이, 검정력과 유의수준 등에 의해 결정되어진다. 일반적으로 수학적으로 계산된 피험자수에 중도탈락 예상치를 고려한 피험자수를 추가하여 최종적인 실험참가자수를 결정하는데 본 논문에서는 이론적인 계산식에서부터 중도탈락을 고려하여 피험자수를 결정하는 방법을 제안한다. 임상시험에서 많은 자료는 경시적(longitudinal) 형태를 갖고, ITT(intention to treat) 실험의 경우 중도탈락이 생기면 결측값으로 처리하지 않고 탈락직전에 관측된 값을 최종값으로 대체하는 LOCF(last observation carried forward) 방법을 주로 사용한다. 이러한 LOCF 방법은 피험자수 계산에 사용했던 분산과 유효차이 값의 가정에 왜곡을 가져오기 때문에 우리가 원하는 검정력을 보장 받지 못할 수 있다. 본 연구에서는 중도탈락률에 관한 정보를 포함하는 피험자수의 결정식을 제안하고 평균의 동일성 검정 경우에 검정력을 비교하여 이러한 산출방식이 합리적임을 실증하였다.

• 한국콘텐츠학회논문지
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• 제16권7호
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• pp.513-521
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• 2016

본 연구는 간호대학생의 분만실 실습 중 수행내용을 파악하고 임상실습 환경에 따른 간호대학생의 실습 수행도 및 만족도를 분석하여 실습의 질 향상을 위한 개선방안을 제시하고자 하였다. 연구결과 간호대학생의 분만실 임상실습은 대부분 관찰 위주로 진행되고 있었고, 제한된 영역에서만 직접수행과 보조적 수행을 경험하였다. 간호대학생의 임상수행 만족도는 69%정도의 비교적 낮은 수준을 보였다. 임상실습지에 따른 차이를 분석한 결과 여성전문병원의 분만실에서 실습 한 간호대학생은 종합병원에서 보다 더 많은 관찰을 수행 할 수 있었고, 그에 따라 만족도 점수 또한 높았다. 분만실 임상실습에서 관찰 및 보조적 수행이 많을수록 만족도는 상승하였다. 결과에서 확인된 실습 중 부족한 직접수행은 시뮬레이션기반 임상실습 등을 통해 보완할 수 있을 것이다. 또한 병원 실무자와의 긴밀한 의사소통을 기반으로 실습지를 확보하고, 다양한 간호대상자를 경험하고 관찰할 수 있도록 지도하는 것은 간호대학생의 임상실습 만족도와 질 향상을 위한 전략으로서 제시될 수 있겠다.

• 대한치과교정학회지
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• 제47권5호
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• pp.334-339
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• 2017

Objective: Teeth discoloration is a rare orthodontic complication. The aim of this study was to report the clinical progression of discoloration during orthodontic treatment. Methods: Discolored teeth, detected during orthodontic treatment between January 2003 and December 2012 by a single dentist using similar techniques and appliances, were analyzed. Results: The total number of teeth that showed discoloration was 28. Progression of discoloration was evaluated in only 24 teeth that were observed without any treatment. During the observation period, the discoloration "improved" in 8 of the 24 teeth (33.3%) and was "maintained" in 16 (66.6%). The electric pulp test performed at the time of initial detection of discoloration showed 14.3% positivity, which improved to 21.4% at the final follow-up. None of the initial and final follow-up radiographic findings showed any abnormalities. Conclusions: When teeth discoloration is detected during orthodontic treatment, observation as an initial management is recommended over immediate treatments.