• Korean Journal of Veterinary Service
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• v.45 no.2
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• pp.71-77
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• 2022

African swine fever (ASF) is a fatal viral disease in pigs, with a short incubation period and causing immediate death. Few studies exist on the Asian epidemic ASF virus (ASFV) challenge in older pigs, including growing and fattening pigs and sows. We aimed to investigate clinical outcomes, pathomorphological lesions, and viral distribution in organs of 3-month-old growing pigs that were inoculated with the ASFV isolated in Vietnam. The clinical outcomes were recorded daily, and the dead or euthanized pigs immediately underwent necropsy. Viral loads were determined in 10 major organs using quantitative polymerase chain reaction. The average incubation period in growing pigs was more delayed (5.2±0.9 dpi) than that in weaned pigs, and the clinical signs were milder in growing pigs than in weaned pigs. The digestive and respiratory clinical signs in growing pigs showed at the end period of life, but these were observed at an early stage of infection in weaned pigs. The pathomorphological features were severe and nonspecific with hemorrhagic lesions in various organs. The viral loads in organs from growing pigs were higher than those from piglets, and the number of viral copies was related to gross lesions in the tonsil and intestine. In the absence of vaccines against ASF, early clinical detection is important for preventing the spread of the virus. Our findings elucidated that the clinical signs and gross lesions in growing pigs differed from those in weaned pigs, which provide valuable information for diagnosis of pigs with suspected ASF infection.

• Quality Improvement in Health Care
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• v.30 no.1
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• pp.120-131
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• 2024

Purpose: This study aimed to evaluate the impact of implementing a clinical pathways (CPs) on the clinical outcomes and costs of patients undergoing breast cancer surgery. Methods: This retrospective cohort study included patients who were newly diagnosed with primary breast cancer at the Samsung Medical Center between 2014 and 2019 (N=8482; 2931 patients in the pre-path and 5551 patients in the post-path). Clinical outcomes included reoperation during hospitalization, readmission, and emergency room visits within 30 days of discharge. The cost data for each unit were obtained from an activity-based management accounting system. We performed an interrupted time series analysis. Results: The post-path period showed a significantly shorter hospital length of stay (LOS) than the pre-path period (6.3 days in pre-path vs. 5.0 days in post-path; -1.3 days' difference; p=.001), and fewer reoperations during hospitalization and within 30 days after discharge than the pre-path period. After adjusting for inflation rates and relative value scores, the model demonstrated savings of $146 per patient in the post-path for total costs, and $537 per patient for patient out-of-pocket costs (p=.001). Conclusion: CPs can help reduce costs without compromising the quality of care by reducing the number of reoperations, readmissions, and complications.

• Current Optics and Photonics
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• v.8 no.4
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• pp.327-344
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• 2024

Optical phantoms are essential in optical imaging and measurement instruments for performance evaluation, calibration, and quality control. They enable precise measurement of image resolution, accuracy, sensitivity, and contrast, which are crucial for both research and clinical diagnostics. This paper reviews the recent advancements and challenges in phantoms for optical coherence tomography, photoacoustic imaging, digital holographic microscopy, optical diffraction tomography, and oximetry tools. We explore the fundamental principles of each technology, the key factors in phantom development, and the evaluation criteria. Additionally, we discuss the application of phantoms used for enhancing optical-image quality. This investigation includes the development of realistic biological and clinical tissue-mimicking phantoms, emphasizing their role in improving the accuracy and reliability of optical imaging and measurement instruments in biomedical and clinical research.

• Korean Circulation Journal
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• v.54 no.8
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• pp.454-465
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• 2024

Background and Objectives: The popliteal artery is generally regarded as a "no-stent zone." Limited data are available on the outcomes of drug-coated balloons (DCBs) for popliteal artery disease. This study aimed to evaluate the 12-month clinical outcomes among patients who received DCB treatment for atherosclerotic popliteal artery disease. Methods: This prospective, multicenter registry study enrolled 100 patients from 7 Korean endovascular centers who underwent endovascular therapy using IN.PACT DCB (Medtronic) for symptomatic atherosclerotic popliteal artery disease. The primary endpoint was 12-month clinical primary patency and the secondary endpoint was clinically driven target lesion revascularization (TLR)-free rate. Results: The mean age of the study cohort was 65.7±10.8 years, and 77% of enrolled patients were men. The mean lesion length was 93.7±53.7 mm, and total occlusions were present in 45% of patients. Technical success was achieved in all patients. Combined atherectomy was performed in 17% and provisional stenting was required in 11%. Out of the enrolled patients, 91 patients completed the 12-month follow-up. Clinical primary patency and TLR-free survival rates at 12 months were 76.0% and 87.2%, respectively. A multivariate Cox regression analysis identified female and longer lesion length as the significant independent predictors of loss of patency. Conclusions: DCB treatment yielded favorable 12-month clinical primary patency and TLR-free survival outcomes in patients with popliteal artery disease.

• Journal of Acupuncture Research
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• v.30 no.5
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• pp.227-233
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• 2013

Objectives : The purpose of this study was to report the clinical effects of catgut-embedding acupuncture therapy on plantar fasciitis. Methods : Two patients were treated mainly with catgut-embedding acupuncture therapy and partly with other Korean medicine modalities. Catgut-embedding acupuncture therapy was applied once a week for three weeks, and follow-up observation was conducted by telephone survey two months after the first treatment. Results : In these two cases, the pain numerical rating scale(NRS) gradually decreased from 8 to 1, and the pain relief as well as the improvement in ambulatory function was maintained at two-month follow-up. Conclusions : Catgut-embedding acupuncture therapy could be effective for pain-reduction and functional improvement in plantar fasciitis.

• Journal of Acupuncture Research
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• v.30 no.5
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• pp.219-226
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• 2013

Objectives : The purpose of this study is to report the effect of Korean medicine treatment on a patient with brachial plexus injury. Methods : The patient with symptoms of pain and dysesthesia on right forearm and hand was treated with acupuncture treatment, herbal medicine, moxibustion and physical treatment. Improvement of the patient's symptoms was evaluated by Hepatic dullness sound, NRS, VAS, SF-36 bodily pain, grip strength. Results : After 42 days of treatment, NRS score significantly decreased. VAS score, SF-36 bodily pain and grip strength showed moderate improvement. Conclusions : This results suggest that Korean medicine treatment may be effective in reducing the symptoms of brachial plexus injury.

• Journal of Korean Physical Therapy Science
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• v.28 no.2
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• pp.40-45
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• 2021

Purpose: The purpose of this study is to find the perceived level of professionalism of physical therapy student who experienced clinical practice. Design: Cross-sectional study. Methods: The subjects of the study were conducted for 3 months from March to June, 2017, and randomly selected physical therapy student who experienced clinical practice in Chungnam-Do. The 138 students in cross-sectional survey were done via Korean of Professionalism In Physical Therapy: Core Values (PPTCV). The questionnaire data analyzed by SPSS 19.0 version. Results: The mean scores of PPTCV were accountability 41.34±0.83, altruism: 19.67+0.90, compassion/caring 43.82±0.81, excellence 45.57±0.80, integrity 43.69±6.16, professional duty 28.67±4.70, and social responsibility 45.84±7.64. Conclusion: Physical therapy students who experienced clinical practice had overall high scores.

• The Journal of Korean Medical History
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• v.23 no.1
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• pp.105-113
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• 2010

Seungjeongwon Ilgi["承政院日記"], the Diaries of Royal Secretariat of the Joeson Dynasty is the most massive compilation of records in Korean history. Medical records in Seungjeongwon Ilgi have been studied but the procedures of clinical discussion[議藥] have not yet been studied. In this paper, main agents of clinical discussion, formation of participant doctor system, particularity of clinical discussion in Royal Court and problems derived from it will be discussed. Main agents of clinical discussion were court doctors[內醫], royal doctors[御醫] and participant doctors[議藥同參]. The king himself decided ultimately as a matter of form. Head of the Medical Dpt. of the Palace[藥房都提調] was in charge of attending to king, but head of the court doctor[首醫] led the actual discussion of deciding treatment. The Medical Dpt. of the Palace[內醫院] was divided into three sectors-court doctor division, acupuncture doctor division and participant doctor division. Palace doctors payed a great attention to avoid serious error. This tendency led them occasionally to passive management. Sometimes aggressive treatment is needed in the course of treating disease, but palace doctors tended to choose slow and gradual methods. It induced minor conflict between palace doctors and participant doctors from outside palace, because doctors from outside palace subordinated effectiveness. Their opinion had not been always recognized by court doctors. However, their role was meaningful because they provided flexibility to the rigidity of clinical discussion in the palace. It is important to evaluate clinical records in Seungjeongwon Ilgi["承政院日記"]. If we have broader eye on the clinical procedure in the palace, we can estimate the value of the contents more objectively and accurately.

• 대한임상약리학회:학술대회논문집
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• 1998.12a
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• pp.12-12
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• 1998

• 대한임상약리학회:학술대회논문집
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• 2005.12a
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• pp.3-3
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• 2005