• 제목/요약/키워드: Clinical course

검색결과 1,623건 처리시간 0.118초

Clinical Outcomes of Atypical Inflammatory Variants of Abdominal Aortic Aneurysm

  • Cho, JooHyun;Bang, Jung Hee;Jeong, Sang Seok;Yi, Junghoon;Yoon, Sung Sil;Cho, Kwangjo
    • Journal of Chest Surgery
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    • 제53권6호
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    • pp.353-360
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    • 2020
  • Background: Most abdominal aortic aneurysms are degenerative atherosclerotic aneurysms. Inflammatory or infected abdominal aortic aneurysms, which show a slightly different clinical course, are rarely encountered in clinical settings. Therefore, we aimed to investigate the clinical course of these variants of abdominal aortic aneurysms. Methods: This retrospective study included 32 patients with atypical inflammatory or infected abdominal aortic aneurysms who underwent emergent graft replacement between November 1997 and December 2017. Patients were followed up at the outpatient clinic for a mean period of 4.9±6.9 years. We analyzed the patients' clinical course and compared it with that of patients with atherosclerotic abdominal aortic aneurysms. Results: There was 1 surgical mortality (3.0%) in a case complicated by aneurysmal free rupture. In 2 cases of infected abdominal aortic aneurysms, anastomotic complications developed immediately postoperatively. During the follow-up period, 10 patients (30%) developed graft complications, and 9 of them underwent reoperations; of these, 2 patients (22.2%) died of postoperative complications after the second operation, whereas 2 patients survived despite graft occlusion. Conclusion: Patients with inflammatory abdominal aneurysms frequently develop postoperative graft complications requiring secondary surgical treatment, so they require close mandatory postoperative follow-up.

Asymptomatic Bile Duct Dilatation in Children: Is It a Disease?

  • Son, Yeo Ju;Lee, Mi Jung;Koh, Hong;Kim, Seung
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제18권3호
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    • pp.180-186
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    • 2015
  • Purpose: Bile duct dilatation is a relatively common sonographic finding; nevertheless, its clinical significance in children is controversial because little research has been done in the area. Therefore, we investigated the natural course and clinical significance of biliary duct dilatation in children. Methods: We performed a retrospective study of 181 children (range, 1-day-old to 17-year-old) in whom dilatation of the intrahepatic duct and/or common hepatic duct and/or common bile duct was detected by abdominal ultrasonography at the Severance Children's Hospital between November 2005 and March 2014. We reviewed and analyzed laboratory test results, clinical manifestations, and clinical course in these patients. Results: Pediatric patients (n=181) were enrolled in the study and divided into two groups. The first group included 59 subjects, without definitive cause of bile duct dilatation, who did not require treatment; the second group included 122 subjects, with definitive cause of bile duct dilatation or underlying biliary disease, who did require treatment. In the first group, 24 patients (40.7%) showed spontaneous resolution of bile duct dilatation, 20 patients (33.9%) showed no change, and 15 patients (25.4%) were lost to follow-up. In the second group, 31 patients were diagnosed with choledochal cysts, and 91 patients presented with biliary tract dilatations due to secondary causes, such as gallbladder or liver disease, post-operative complications, or malignancy. Conclusion: Biliary dilatation in pediatric patients without symptoms, and without laboratory and other sonographic abnormalities, showed a benign clinical course. No pathologic conditions were noted on follow-up ultrasonography.

Glyphosate 음독의 임상양상 (Atypical Clinical Course of after Glyphosate Herbicide Intoxication)

  • 김용원;김현;차경철;신형진;차용성;이강현;황성오
    • 대한임상독성학회지
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    • 제9권1호
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    • pp.8-13
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    • 2011
  • Purpose: Although glyphosate-surfactant herbicide intoxication is relatively mild toxic in humans, we encountered an atypical clinical presentation. We performed this study to understand the atypical clinical course and factors associated with severe intoxication after glyphosate ingestion. Methods: We conducted a retrospective study of 61 patients (male 43, mean age $54{\pm}18.8$ years) who were presented with glyphosate ingestion between March 1997 and March 2011. The severe intoxication group was defined as patients with systolic blood pressure less than 90 mmHg, respiratory distress needing intubation, or altered mental state. Results: Of the 61 patients, 22 patients (36.1%) had a severe clinical course, 1 patient (1.6%) had died and 1 patient (1.6%) had moribund discharge. The most common symptoms were nausea with or without vomiting which occurred in 30 patients (49.2%). Twenty-seven patients had metabolic acidosis that was the second most common medical complication. Advanced age, pH, base excess, $HCO_3$, Sat, creatinine, X-ray abnormalities and ECG abnormalities were significant factors. Hemoglobin, platelet, $pO_2$, $pCO_2$, BUN, sodium, potassium and AST levels were not different comparing the laboratory characteristics between the severe and mild intoxication groups. Conclusion: The results of this study showed that severe intoxication occurred in 22 patients (36.1%) after glyphosate intoxication. Advanced age, pH, base excess, $HCO_3$, Sat, creatinine, X-ray abnormality and ECG abnormalities were significant predictive factors for severe intoxication in patients with glyphosate surfactant herbicide poisoning.

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임상실습에 대한 방사선 전공 학생들의 인식에 관한 연구 (A Study on the Perception of Students in the Radiation Study on the Clinical Practices)

  • 이병렬;김현길;윤명관;이기종;차상영;임청환
    • 대한방사선기술학회지:방사선기술과학
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    • 제37권3호
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    • pp.211-221
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    • 2014
  • 임상실습은 전공분야에 관한 실제적 경험을 의료기관에서 현장 실습교육을 통해서 배울 수 있는 좋은 기회가 되고 있다. 이에 임상실습이 진행되는 가운데 임상 지도강사와 학생의 임상실습에 관한 인식을 비교 연구하고자 한다. 수도권에 소재하고 있는 방사선을 전공하는 재학생 중에 2013년 임상실습을 마친 학생을 대상으로 하였다. 본 연구를 위해 고안된 설문지를 사용하여 진행하였으며, 회수된 설문지 275부를 통계프로그램 SPSS(12.0 version)을 사용하여 빈도분석, 교차분석, 카이제곱 검정, McNemar검정을 실시하였다. 방사선 전공을 선택한 동기는 높은 취업률 때문(44.0%)이고, 학과에 대한 만족도는 보통(53.1%)이라고 대답하였다. 8주의 임상실습 기간에 대해 51.3%가 적절하다고 인식하였으며, 임상실습 시기는 3년 과정의 학생은 2학년 겨울방학(47.3%), 4년 과정의 학생은 3학년 1학기(27.7%)로 나타났다. 임상실습 동안 학생들은 전문지식의 부족(32.4%)을 느꼈으며, 실습교육의 일부 내용이 학교에서 이루어지는 교육과 차이가 있다(68.4%)고 대답하였다. 임상실습교육에 대해 대부분 만족하는 것으로 나타났으며 그중에서 임상실습에 대한 중요성의 인식은 $3.94{\pm}0.89$로 나타났다. 실습의 실시 전과 후에 방사선사 취업에 대한 인식의 변화는 84.1%에서 82.9%로 나타났다. 방사선사 취업을 원하는 이유는 직업의 안정성으로 실습 전 49.0%와 실습 후 46.0%, 취업을 원하지 않은 이유는 적성 및 소질에 맞지 않아서가 실습 전 37.0%와 실습 후 40.7%로 대답하였다. 취업을 위한 대학교육이 아닌 유능한 인재를 통한 방사선사의 위상을 높일 수 있는 내실 있고 만족도 높은 대학교육이 이루어 질 수 있는 노력이 필요하고 교육대상자인 학생들에게 효과적인 교육이 이루어 질 수 있는 임상실습시기와 기간에 대한 폭넓은 논의가 지속적으로 필요하다고 사료된다.

A Case of Rhabdoid Meningioma

  • Han, Jung-Ho;Seol, Ho-Jun;Kim, Dong-Gyu;Jung, Hee-Won
    • Journal of Korean Neurosurgical Society
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    • 제39권2호
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    • pp.144-147
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    • 2006
  • Rhabdoid meningioma is an uncommon meningioma variant, which was initially described in 1998 by Perry et al. It is classified as a variant corresponding to grade III in the recent World Health Organization[WHO] classification of tumors of the nervous system, because of its unique histopathological features and its highly aggressive clinical course. To date there were still a lot of arguments about their developmental patterns and the treatment strategy especially for rhabdoid meningiomas lacking other histological features of malignancy. Although the exact causes of rhabdoid transformation of a benign meningioma are unknown, malignant transformation long duration after surgical resection under an underlying predilection for malignancy is suggested in our case. And we suggest that any histological rhabdoid features in recurrent meningiomas or even in primary cases seem to indicate the malignant clinical course and the need for aggressive treatments, because transformation from a benign or atypical one to a malignant one seems to occur at last.

Feasibility Assessment of Physical Factors of Rectal Cancer Short-Course Chemoradiotherapy with Delayed Surgery

  • Koo, Jihye;Chung, Mijoo;Chung, Weon Kuu;Jin, Sunsik;Kim, Dong Wook
    • 한국의학물리학회지:의학물리
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    • 제29권4호
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    • pp.143-149
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    • 2018
  • To verify the correlations between the clinical outcomes and physical factors of short-course chemoradiotherapy (SCRT) and long-course chemoradiotherapy (LCRT) with delayed surgery in patients with rectal cancer. Seventy-two patients with rectal cancer were enrolled in this study. Nineteen patients were treated with SCRT (25 Gy, 5 fractions) by intensity-modulated radiation therapy (IMRT), and 53 patients were treated with LCRT (50.4 Gy, 28 fractions) by three-dimensional conformal radiation therapy (3DCRT). Various physical factors for the target and organs at risk (OARs) were calculated to compare the clinical outcomes. The organ equivalent dose (OED) and lifetime attributable risk (LAR) of bowels and bladders were similar between the SCRT and LCRT groups, whereas the values of femurs were higher in the LCRT group. The equivalent uniform dose and normal tissue complication probability were higher in the LCRT than the SCRT group for most organs. Treatment complications, including anastomotic leakage, bowel adhesion, and hematologic toxicity, were not significantly different between SCRT and LCRT groups. CIs were $0.84{\pm}0.2$ and $0.61{\pm}0.1$ for SCRT and LCRT, respectively. The CVIs were $1.07{\pm}0.0$ and $1.10{\pm}0.1$, and the HIs were $0.09{\pm}0.0$ and $0.11{\pm}0.1$ for SCRT and LCRT, respectively. The sphincter-saving rates were 89.5% and 94.3% for SCRT and LCRT, respectively. The complete pathologic remission rates were 21.1% and 13.2%, and the down-staging rates were 47.4% and 26.4% for SCRT and LCRT, respectively. SCRT with IMRT is comparable to conventional LCRT in both physical indexes and clinical outcome. The preoperative SCRT, compensated by IMRT, is an effective and safe modality.

대한감각통합치료학회 주최 "치료과정" 보고 (The Report of Sensory Integration Treatment Course in The Korean Academy of Sensory Integration(KASI))

  • 김경미;최정실
    • 대한감각통합치료학회지
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    • 제4권1호
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    • pp.65-70
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    • 2006
  • Objective : Korean Academy of Sensory Integration(KASI) planned and executed intensive sensory integration treatment course for children with the sensory integrative dysfunction and therapists, to suggest practical guideline for therapists through individual supervision, lecture, simulation therapy, observation, case study and free play etc. Method : The course was held during 5days in the children's center for developmental support that set up sensory integration tools. The course executed the 4 individual interventions, 1 simulation therapy, 1 observation, 4 free play sessions that consisted of 6 children with sensory integrative dysfunction and 6 therapists who manage them and 3 supervisors and 2 managers. Results : Their parents reported the satisfaction degree of the treatment course service was above 84%. Therapists also had a chance to understand the broader sensory integrative interventions through the supervision and various educational programs. Conclusions : Intensive treatment course can provide parents and therapists with satisfaction of the programs. Therapists can especially experience reeducation individually through supervision and lectures.

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간호학 임상실습 입문 교육과정(Introduction to Clinical Nursing) 개발과 교육 효과 (The Development and Evaluation of a New Educational Program, Introduction to Clinical Nursing, for Third Year Nursing Students)

  • 송경애;박현정;염혜아;이종은;주가을;김희주
    • 기본간호학회지
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    • 제19권3호
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    • pp.322-333
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    • 2012
  • Purpose: The purpose of this study was to evaluate the effects of a newly developed Introduction to Clinical Nursing (ICN) program on critical thinking skills, communication competence, self-efficacy, and clinical performance self-confidence in nursing students in their third year. Methods: One group pre-test and post-test design was used with three data collection time points (pre-test, post-test1 and post-test2). Participants were 74 third year nursing students approaching their first clinical practicum. The new program included (a) simulated clinical encounters regarding situations of assessing hospitalized patents and caring for patients with oxygenation needs, (b) objective structured clinical examination of skills, (c) lectures, and (e) field trips. Data were analyzed using paired t-tests. Results: After the ICN course, critical thinking skills(significant only between pretest and post-test2), communication competence, and clinical performance self-confidence improved significantly (p<.05). There was no improvement in the self-efficacy total score but there was significant improvement in the subscale, self-regulatory efficacy. Conclusions: The study results indicate that the ICN course may be effective in increasing critical thinking skills, communication competence, and clinical performance self-confidence in nursing students. However, the effect size was very small and modifications of this program should be considered to develop more cost-effective educational programs.

임상치과 영역 교과목 분석을 통한 통합교육과정에 대한 고찰 : 한국, 일본 일부 치위생학과 사례를 중심으로 (Analysis of a clinical dentistry course to study the need for integrated curriculum : in the case of dental hygiene department in Korea and Japan)

  • 신보미;배수명;신선정
    • 한국치위생학회지
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    • 제19권3호
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    • pp.331-342
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    • 2019
  • The purpose of this study is to analyze the clinical dentistry curriculum in Korea and Japan in order to review the application of integrated curriculum in the field. We collected the clinical dentistry syllabi for 2015-16 of the department of dental hygiene of Korea G University and Japan N University. Using the data from Korea, items that were duplicated and integrated were classified by the subjects covered in clinical dentistry. In addition, through case studies conducted in Korea and Japan, we analyzed and compared the credits, class hours, teaching methods, and evaluation methods, by subject. In Korea the total class hours in clinical dentistry, including clinical practice, was 1,095, and in Japan it was 1,104. In Korea, the syllabus covered by each department consisted of about 200 hours centering on theoretical lectures. In Japan, the integrated form of clinical dentistry was taught, and the instructions included all the contents of clinical dental study and also problem-based learning for approximately 100 hours. To strengthen the competence of dental hygienists as professionals, who are actively involved in dental practice, it is necessary to integrate the education contents of segmented clinical dentistry from the perspective of dental hygiene. It is also important to apply teaching methods that can help students improve their ability to solve problems.