• Korean Journal of Clinical Pharmacy
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• v.10 no.1
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• pp.42-49
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• 2000

The undergraduate curricula of the twenty pharmacy schools in Korea were analyzed in order to find out the relationship between the Korean Pharmacist Licensure Examination (KPLE) and the Pharmacy Education. The results of this survey indicated that the Pharmacy Education was highly related to KPLE. During the 1999 academic year, there were 1,853 undergraduate courses offered by the twenty pharmacy colleges excluding pre-pharmacy courses. Of the total courses 73\%$ were related to the twelve subject of KPLE. Eighty percent were related to the basic pharmacy. Only $13\%$ were related to the pharmacy practice. The courses related to the Medicinal Chemistry were 16\% of the basic pharmacy courses. The numbers and the names of the subjects of KPLE have not been change during the past 3- years. Recently, the names of the subjects of KPLE have not been changed during the past 30 years. Recently, the National Health Personnel Licensing Examination Board advised to change the courses from the drug-oriented curriculum to a practice-oriented one. Therefore, it will be better that the curriculum of the undergraduate pharmacy program to be re-organized focusing on the divisions of the courses, not on the name of the courses. The number of the under graduate courses should be reduced by combining the related courses. The more courses in the field of patient-oriented pharmacy practice are needed to be added to the undergraduate curriculum in order to produce the clinical pharmacists.

• Proceedings of the Ginseng society Conference
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• 2006.05a
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• pp.69-70
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• 2006

Purpose: Panaxadiols are more potent than panaxatriols as far as insulin secretory activity is concerned. In this study, we examined insulin secretory activity and mechanism of compound K (CK), a major intestinal bacterial metabolite of ginsenosides. Method: Insulin secretory activity of CK was examined using pancreatic beta cells and in Oral Glucose Tolerance Test assay. In addition, insulin secretory mechanism was studied in terms of calcium dependent or independent pathways. Results: In vitro, CK enhanced the insulin secretion concentration-dependently when compared to glucose-stimulated control cells. Insulin secretory mechanism of CK seems to block ATP sensitive K channels, which was confirmed by diazoxide (K channel opener) but, insulin resistance ameliorating activity of CK can't be ruled out. In vivo, CK showed hypoglycemic effect in OGTT.

• Korean Journal of Clinical Pharmacy
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• v.14 no.1
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• pp.36-45
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• 2004

• 한국임상약학회:학술대회논문집
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• 1994.11a
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• pp.97-130
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• 1994

'The formulation of a research problem is far more often essential than its solution, which may be merely a matter of mathematical or experimental skill. To raise new questions, new possibilities, to regard old problems from a new angle requires creative imagination and marks real edvance in science.'

• Proceedings of the PSK Conference
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• 2001.10a
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• pp.160.2-161
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• 2001

• Proceedings of the PSK Conference
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• 2000.10a
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• pp.281.2-282
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• 2000

• Proceedings of the PSK Conference
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• 2000.10a
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• pp.279.1-279.1
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• 2000

• Korean Journal of Clinical Pharmacy
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• v.24 no.1
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• pp.45-52
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• 2014

Objective: To evaluate the clinical manifestations and causative drugs of the outpatient adverse drug reactions (ADRs) reported by community pharmacy. Methods: From April 2013 to September 2013, all outpatient ADRs reported by community pharmacy to Regional Pharmacovigilance Center of Korean Pharmaceutical Association were included. The causality of ADRs was assessed by the criteria of WHO-Uppsala Monitoring Centre. The clinical features and the offending drugs were analyzed using the WHO-Adverse Reaction Terminology and the classification of American Hospital Formulary Service Drug Information, respectively. Results: 2,826 (97.0%) of the total 2,912 ADRs had causal relationship. The 1,923 patients with mean age of 55.1 years and female fraction of 66.5% were included in the ADRs. Gastrointestinal (33.6%), nervous system (14.9%), and skin (13.5%) symptoms were common in ADRs. Analgesic drugs (19.7%), gastrointestinal drugs (17.7%), and central nervous system drugs (11.0%) were prevalent offending drugs. The leading causative generic drug was the complex of acetaminophen and tramadol. Among 203 ADRs by the nonprescription drugs, the most common clinical features were skin (37.4%) and gastrointestinal (23.6%) symptoms and the most prevalent offending drugs were analgesic drugs (40.0%) and mucocutaneous system drugs (16.3%). The combination of acetaminophen and chlorzoxazone was the leading causative generic in nonprescription drugs. Conclusion: In this study, gastrointestinal symptom was the most common manifestation and analgesic drug was the most common causative drug in outpatient ADRs reported by community pharmacy.

• Korean Journal of Clinical Pharmacy
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• v.3 no.2
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• pp.175-185
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• 1993

The goal of this clerkship is to expose the student to basic skills needed fir a patient oriented pharmacist to assume an existing clinical role and participate in therapeutic decision making processes. As the pharmacy profession has moved from the traditional product orientation to a patient orientation, curricula within the college of pharmacy have evolved to include more experiential coursework to lister this patient orientation. This change has been supported by the philosophy of pharmaceutical care which encourages pharmacists to assume a patient advocacy role in optimizing a patient's drug therapy while minimizing the adverse effects of the medication. The role of experiential education, and especially the clerkship experience will be to hasten and enhance the development of this concept and philosophy for pharmacy students.

• Korean Journal of Clinical Pharmacy
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• v.21 no.3
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• pp.193-207
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• 2011

Purpose: The purpose of this study is to assess appropriateness of current standard for insurance coverage by Health Insurance Review & Assessment Service (HIRA) on chemotherapy used in the treatment of advanced non-small cell lung cancer (NSCLC), by reviewing a variety of clinical evidences, and thereby, if needed, to propose an updated evidence-based recommendations. Methods: We collected data from HIRA regarding on the insurance standard which includes the scope and conditions for coverage on systemic chemotherapy of NSCLC. We performed a search for clinical databases and examined the most current clinical evidence from clinical literature including various clinical practice guidelines. Based on the collected data the appropriateness of HIRA standard for insurance coverage of chemotherapy of NSCLC was assessed. Results: Collected data demonstrated that HIRA standard did not reflect the most current clinical practice and evidence. Some were inappropriately listed in HIRA formulary and accepted as a chemotherapy being covered by insurance, despite the lack of evidences of clinical efficacy or superiority over other chemotherapeutic agents or regimens. In addition, there seems to be a need for a modification on the standard for insurance coverage of certain newer chemotherapeutic agents based on the current accumulated data showing their clinical efficacy and benefits in the selected group of NSCLC patients. Therefore, we concluded that current HIRA standard for insurance coverage on chemotherapy of NSCLC needs to be revised and we proposed an updated recommendation based on these latest clinical evidences. Conclusion: The standard for insurance coverage of chemotherapy should be continually examined its appropriateness based on the most recent clinical evidences in a timely manner so as to provide the most effective and safe therapy to cancer patients.