• Title/Summary/Keyword: Clinical Data

Search Result 10,755, Processing Time 0.037 seconds

Safety, High Quality, Confidence of Kaneka CoQ10

  • Fujii, Kenji
    • Proceedings of the Korean Society of Applied Pharmacology
    • /
    • 2006.11a
    • /
    • pp.139-145
    • /
    • 2006
  • Kaneka Corporation (Kaneka) has been manufacturing CoQ10 under GMP regulation since 1977. Kaneka has a sophisticated quality control system and has been supplying high quality CoQ10 materials to the worldwide customers (Kaneka CoQ10) for about 30 years. Kaneka CoQ10 is characterized by a lot of safety data, which are derived from clinical trials with healthy volunteers (single-dose and 4-week multi-dose safety studies), animal studies (13-week sub-chronic study in dogs and 52-week chronic study in rats), three types of mutagenicity test, six type of skin irritation test (for cosmetics), and others. The risk assessment of CoQ10 was performed by Council for Responsible Nutrition (USA). They reviewed many of available clinical data including clinical trials using Kaneka Q10, and concluded that the upper level for supplements (ULS) of CoQ10 is 1,200 mg/day (Hathcock and Shao. 2006, Regulatory Toxicology and Pharmacology, 45, 282 - 288).

  • PDF

Membranes for the Guided Bone Regeneration

  • Lee, Sang-Woon;Kim, Seong-Gon
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.36 no.6
    • /
    • pp.239-246
    • /
    • 2014
  • Many kinds of membrane have been used for the guided bone regeneration (GBR) technique. However, most membranes do not fulfill all requirements for the ideal membrane for the GBR technique. Among them, collagen membrane has been most widely used. However, its high price and weak tensile strength in wet condition are limitations for wide clinical application. Synthetic polymers have also been used for the GBR technique. Recently, silk based membrane has been considered as a membrane for the GBR technique. Despite many promising preclinical data for use of a silk membrane, clinical data regarding the silk membrane has been limited. However, silk based material has been used clinically as vessel-tie material and an electrospun silk membrane was applied successfully to patients. No adverse effect related to the silk suture has been reported. Considering that silk membrane can be provided to patients at a cheap price, its clinical application should be encouraged.

Primary Writing Tremor Type B, Writing Posture-specific? (원발성 서자진전 B형, 서자자세-특수성인가?)

  • Seo, Man-Wook
    • Annals of Clinical Neurophysiology
    • /
    • v.2 no.2
    • /
    • pp.95-100
    • /
    • 2000
  • Purpose : Primary writing tremor(PWT) can be classified as either type A or type B depending on whether tremor appeared during writing or whilst writing and also on adopting the hand postures normally used for writing. Through the clinical experience author has had an impression that PWT type B may not be purely dependant on specific writing postures. The objective of this study was to clarify whether PWT type B have writing posture-specificity or not. Results : The data indicated that type B PWT is not writing posture-specific. Various pronation and supination postures could evoke tremor as well as writing postures. Furthermore most of other pronation- and supination-related tasks could evoke tremors as well as action of writing. Conclusions : The present data suggest that PWT should be limited only on the pure form of task-spesific PWT type A.

  • PDF

A Research of Body Size Analysis and Graphing in 20yrs Korean Women (20대 한국 여성의 체위 분석과 도식화 연구)

  • Kim, Dong-Il;Park, Hyun-Jung
    • The Journal of Korean Obstetrics and Gynecology
    • /
    • v.21 no.1
    • /
    • pp.179-198
    • /
    • 2008
  • Purpose: Obesity is already a major clinical problem in Korea, so obesity prevention and treatment practices are gradually interested in Korean Medicine doctors. Moreover subjective body shape image entered as a important medical topic recently. To make a graph system for clinical tool which based on the Korean national standard physical scale. Methods: Physical data of the girth of upper arm, abdomen, hip, buttock, flank, calf, and body weight were statistically analyzed, which collected through the fifth national standard physical scale research. And then reviewed those statistical validation. Results: Relationship of the each body scale data and those graphs were fit and right statistically. Conclusion: These new achieved graph system of Korean standard body scales could be adopt as a useful clinical tool for body image related patients such as obesity, PCOD and postpartum patient.

  • PDF

Safety, High Quality, Confidence of Kaneka CoQ10

  • Fujii, Kenji
    • 한국약용작물학회:학술대회논문집
    • /
    • 2006.11a
    • /
    • pp.139-145
    • /
    • 2006
  • Kaneka Corporation (Kaneka) has been manufacturing CoQ10 under GMP regulation since 1977. Kaneka has a sophisticated quality control system and has been supplying high quality CoQ10 materials to the worldwide customers (Kaneka CoQ10) for about 30 years. Kaneka CoQ10 is characterized by a lot of safety data, which are derived from clinical trials with healthy volunteers (single-dose and 4-week multi-dose safety studies), animal studies (13-week sub-chronic study in dogs and 52-week chronic study in rats), three types of mutagenicity test, six type of skin irritation test (for cosmetics), and others. The risk assessment of CoQ10 was performed by Council for Responsible Nutrition (USA). They reviewed many of available clinical data including clinical trials using Kaneka Q10, and concluded that the upper level for supplements (ULS) of CoQ10 is 1,200mg/day (Hathcock and Shao. 2006, Regulatory Toxicology and Pharmacology, $\underline{45}$, 282 - 288).

  • PDF

Predictors of Terminal Care Performance of Clinical Nurses for Cancer Patients (암환자를 돌보는 간호사의 임종간호수행에 영향을 미치는 요인)

  • Noh, Seon-Suk;Lee, Chang-Kwan;Sung, Young-Hee
    • Journal of Korean Critical Care Nursing
    • /
    • v.9 no.2
    • /
    • pp.61-70
    • /
    • 2016
  • Purpose: The purpose of this study was to identify the influences of death perception, terminal care attitude on clinical nurses' terminal care performance for cancer patients. Methods: Data were collected through self-reported questionnaires filled by 526 nurses at a General Hospital in Seoul. Data were analyzed using a multiple regression analysis. Results: Death perception showed a positive correlation with terminal care attitude (r = .45, p < .001), while there was no correlation with terminal care performance. Additionally, terminal care attitude had a positive correlation with terminal care performance (r = .18, p < .001). The explanatory power of nurses' death perception and terminal care attitude toward terminal care performance was 14%. Conclusions: The study results imply that nurses' death perception and terminal care attitude are significant variables affecting terminal care performance.

  • PDF

Hemodynamically Isolated Intracranial Aneurysms on DSA and CEMRA: Clinical and Experimental Data

  • 정태섭;강원석;심용운;임윤철;이승구;주진양
    • Proceedings of the KSMRM Conference
    • /
    • 2001.11a
    • /
    • pp.134-134
    • /
    • 2001
  • Purpose: To evaluate the physiologic background of poorly visualized aneurysms during DSA a contrast-enhanced MRA(CEMRA) due to hemodynamical isolation on clinical and experiment data. Method: Two cases of intracranial aneurysm which were poorly visualized on DSA a CEMRA and one case of intracranial aneurysm which had poor turnover of contrast mediu during DSA were selected for this clinical study. We evaluated the turnover of blood in t terminal aneurysm of handmade elastic silicon phantoms for comparative experiment. Flo experiments with DSA and contrast enhanced MRA were performed in elastic phantoms aneurysm with 3 different diameters (2, 5 and 10 mm) of neck mimicking basilar ti aneurysm, attached to pulsatile pump similar to that of human physiologic parameters. W compared the results with those of computational flow dynamics(CFD).

  • PDF

A literature study of Infectious Mononucleosis in Traditional Chinese Medicine (전염성 단핵구증의 중의학(中醫學) 연구(硏究)에 대한 고찰(考察))

  • Chang, Gyu-Tae
    • The Journal of Pediatrics of Korean Medicine
    • /
    • v.18 no.2
    • /
    • pp.233-249
    • /
    • 2004
  • Objectives : Infectious mononucleosis is a clinical syndrome caused by Epstein-Barr virus that is particularly common in adolescents and children. This study was progressed for current oriental medical treatment of infectious mononucleosis in china. The purpose of this study is the opening oriental medical approach to infectious mononucleosis in Korea Methods : Authors conducted a literature search in data of Traditional Chinese Medical Journal. The data were extracted in a standardized, predefined manner and accessed critically. Results : The study for infectious mononucleosis consists of basic, clinical, experimental study. Basic study consists of etiology & pathogenesis and the rule of treatment. Clinical study consists of symptoms-based treatment and adequate prescription treatment. Experimental study consists of effective herbs and new traditional chinese medical injection. Conclusion : Traditional chinese medical approach using herbs works in children with infectious mononucleosis in Korea.

  • PDF

Factors influencing the customer orientation of clinical dental hygienists (임상치과위생사의 고객지향성에 미치는 영향 요인)

  • Do, Yu-Jeong;Min, Hee-Hong
    • Journal of Korean society of Dental Hygiene
    • /
    • v.20 no.2
    • /
    • pp.189-196
    • /
    • 2020
  • Objectives: This study aims to investigate the impact of clinical dental hygienists on customer orientation and prepare basic data for the rational and efficient human resource management of dental hygienists. Methods: A self-reported questionnaire was completed by 220 dental hygienists from July 7 to August 8, 2019. Data were analyzed using the IBM SPSS Statistics 22.0 program with a significance level of 0.05. Results: The customer orientation of clinical dental hygienists was 4.09, internal marketing was 3.10, organizational citizenship behavior was 3.97, and self-efficacy was 3.91. The variables that most influenced their turnover intention were those related to organizational citizenship behavior. These factors showed a 28.8% variance among dental hygienists. Conclusions: This study recommends the development and application of a program that enhances dental hygienists' customer orientation, recognizes them as internal clients, and improves dental productivity.

The Effects of Aroma Inhalation on Nursing Students' Stress Response and Anxiety before Their First Clinical Practice (향기 흡입법이 간호 대학생의 첫 임상 실습 전 불안과 스트레스 반응에 미치는 효과)

  • Lee, Hea-Sook
    • Research in Community and Public Health Nursing
    • /
    • v.19 no.1
    • /
    • pp.112-119
    • /
    • 2008
  • Purpose: The purpose of this study was to verify the effect of aroma inhalation on nursing students stress responses and anxiety before their first clinical practice. Method: Data were collected during the period from March 5 to March 10, 2007 at K College in a province. There were seventy eight subjects, 35 for the experimental group and 38 for the control group. Aroma oils used were lavender, peppermint and rosemary. Before and after the treatment, the severity of stress and anxiety were evaluated by VAS and a questionnaire. Data were analyzed by descriptive statistics, t-test and $\chi^2$-test with the SPSS program. Result: The score of subjective stress (VAS) decreased significantly after aroma inhalation(p=.000), but status anxiety was not significantly different between the two groups (p=.649). Conclusion: Aroma inhalation can be a useful intervention to reduce nursing student's stress before their first clinical practice.

  • PDF