• Advances in Traditional Medicine
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• v.8 no.2
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• pp.103-110
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• 2008

Herbal medicine is the use of medicinal plants for prevention and treatment of diseases: it ranges from traditional and popular medicines of every country to the use of standardized and tritated herbal extracts. Generally cultural rootedness enduring and widespread use in a traditional medical system may indicate safety, but also efficacy of treatments, especially in herbal medicine where tradition is almost completely based on remedies containing active principles at very low and ultra low concentrations or relying on magical-energetic principles. The efficacy and safety assessments of medicines, whether modern or herbal, invariably encounter challenges or problems during the course of pre-clinical and clinical research. Some of the challenges in evidence-based herbal medicinal research are unique, and the researcher must be cognizant of them in order to safeguard the quality of the data obtained. Key challenges are: the quality of raw materials; appropriateness of biological/pharmacological activity assessment methodology, and data interpretation; standardization methodology; pharmacokinetics and bioavailability of active constituents and metabolites; clinical dosage formulation/production; and clinical study designs and outcome measures.

• The Korean Journal of Emergency Medical Services
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• v.7 no.1
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• pp.95-108
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• 2003

This study was conducted to identify an initial clinical experience of EMT students, so to better understand their' experience in clinical training. The subjects were 30 EMT students of C department of Emergency Medical technology in C city, who were demonstrating at the emergency room in C, T, S, W city. This study was approached by phenomenological method, collected data were analyzed by Colaizzi's method. the results were as a follows. From the protocol, significant statements were organized into 34 formulated meanings. from the formulated meanings, 21themes were identified, organized into 8 theme clusters, and then categories. EMT students got experienced 'tension resulting from new situation', 'fear in contacting with patients', 'lack of knowledge and skill', 'confidence feeling from being adapted', 'facing up to Paramedic role', 'experience of death' and 'stress'. The results of this study are to use as basic data for students attending clinical experience for the first time.

• Journal of Korean Academy of Nursing
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• v.38 no.4
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• pp.561-572
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• 2008

Purpose: The purpose of this study was to understand and analyze the experience of hurt and forgiveness of clinical nurses in Korea. Methods: A phenomenological research method guided data collection and analysis. The subjects were a total of 5 nurses who had experienced hurt and forgiveness. Data was collected through individual in-depth interviews. All interviews were audio taped and transcribed verbatim. Coding was used to establish different concepts and categories. Results: The following three common constituents have been found as a retrospective focus based on the primary hurt related to the clinical situation; recognizing their personal values, obtaining their view about forgiveness, as well as their view of self. Conclusion: The results of this study may contribute to health professionals working in various clinical settings to understand Korean nurses with hurt and forgiveness experiences.

• Translational and Clinical Pharmacology
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• v.26 no.3
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• pp.115-117
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• 2018

This tutorial explains the basic principles of mechanistic ligand-receptor interaction model, which is an operational model of agonism. A growing number of agonist drugs, especially immune oncology drugs, is currently being developed. In this tutorial, time-dependent ordinary differential equation for simple $E_{max}$ operational model of agonism was derived step by step. The differential equation could be applied in a pharmacodynamic modeling software, such as NONMEM, for use in non-steady state experiments, in which experimental data are generated while the interaction between ligand and receptor changes over time. Making the most of the non-steady state experimental data would simplify the experimental processes, and furthermore allow us to identify more detailed kinetics of a potential drug. The operational model of agonism could be useful to predict the optimal dose for agonistic drugs from in vitro and in vivo animal pharmacology experiments at the very early phase of drug development.

• Research in Community and Public Health Nursing
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• v.9 no.2
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• pp.533-549
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• 1998

This descriptive study was designed to measure the degrees of work stress and job satisfaction and use interpersonal conflict resolution strategy as an attempt to provide clinical nurses basic data to develop strategies releasing work stress and improving job satisfaction. These data were collected from 367 clinical nurses working in 9 hospitals nation-wide from May 1, to June 30, 1998. A structured questionaire was used for data collection. The questionnaire included Kim and Koo's work stress scale, Lee's interpersonal conflict resolution strategy scale and a Minesota satisfaction questionnaire. Data analysis was done by the use of the SAS computer program with descriptive statistics, t -test, ANOVA, Scheffe test, Pearson Correlation Coefficient and Cronbach - ${\alpha}$. The results were as follows 1. The mean score of work stress for the subjects was 4.34(SD=0.64). The highest scored reasons for work stress were 'inadequate com pensation' 4.93(SD=0.86), 'lack of professional knowledge and skill' 4.70(SD=0.92) and 'unsatisfactory relationship with superior authorities' 4.63(SD=0.97). The lowest scored reasons were 'unsatisfactory relationship with inferior staff' 3.72(SD=1.02), 'inadequate mechanical environment' 3.72(SD=1.11) and 'interpersonal problems' 3.85 (SD=1.06), The work stress in clinical nurses differed significantly depending on the hospital type (F=4.00, p=0.0082). 2. The clinical nurses used compromise(45.1%) as the best interpersonal conflict resolution strategy. The second was collaboration(32.8%), the third accomodation(14.2%), the forth avoidance(4.2%) and the fifth competition(3.6%). 3. The item score of job satisfaction of the subject was 3.00(SD=0.43), The job satisfaction in clinical nurses differed significantly depending on age(F=5.67, p=0.0000), marital status(t= -1.89, p=0.0511), academic career(F=5.84, 0.0001), official position (F=7.38, p=0.0001), and work career(F=6.33, p=0.0001). 4. The result of the analysis of relationship between work stress and job satisfaction was significant(r= -0.34, p=0.0000). In conclusion, it was found that work stress was very high in clinical nurses. They used interpersonal conflict resolution strategies to release their interpersonal problems and to increase their job satisfaction. Therefore, adequate stress management for clinical nurses will provide them with higher job satisfaction and hence lead to more qualitified nursing care.

• The Journal of Korean Academic Society of Nursing Education
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• v.20 no.2
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• pp.203-211
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• 2014

Purpose: This study was conducted to compare the effects of simulation-based training on knowledge, self-efficacy and clinical performance, underwent before or after the clinical practice for the nursing students. Method: A comparison group design was established with pre-clinical practice group (n=34) and post-clinical practice group (n=34). Both groups participated in simulation-based training before or after the clinical practice at the recovery room. Chi-square test, t-test and paired t-test were performed to analyze the data. Results: Both groups showed significantly higher post-test scores in knowledge and self-efficacy than pre-test scores (p<.001). The group with simulation training performed before their clinical practice (pre-clinical practice group) showed significantly higher self-efficacy (p=.044) than the group with simulation training done after their clinical practice (post-clinical practice group). However, there was no significant difference in the knowledge (p=.922) and clinical performance (p=.887). Conclusion: These findings of the study suggest that simulation based training in pre-clinical practice is effective to enhance the self-efficacy and to improve knowledge and clinical performance of the nursing students.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.17 no.1
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• pp.90-98
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• 2010

Purpose: This study was done to compare the relationships between motivation to achieve, clinical competency, and satisfaction on clinical practice in diploma and baccalaureate nursing students. Method: A descriptive research design was used in this study. The participants were 181 nursing students in B city who were surveyed between June 2 and June 30, 2008 using self-report questionnaires. The collected data were analyzed using the SPSS WIN 14.0. Results: There were significant difference in clinical competency according to satisfaction with college life, and motivation for choice of nursing for baccalaureate students. There was a positive correlation between motivation to achieve and clinical competency. Motivation to achieve and satisfaction in clinical practice, and clinical competency and satisfaction were correlated with clinical practice for students in both diploma and baccalaureate programs. The predictors influencing clinical competency for the nursing students were motivation to achieve, and satisfaction in clinical practice, and education level. Three factors explained 26.8% of clinical competency for nursing students. Conclusion: It is necessary to enhance individual motivation to achieve to improve clinical competency of nursing students. Motivation to achieve needs to be considered in planning programs to enhance clinical competency in nursing students.

• The Journal of Korean Academic Society of Nursing Education
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• v.15 no.2
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• pp.159-165
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• 2009

Purpose: The purpose of this study was to identify clinical competence and to analyze influencing factors on clinical competence for second year college nursing students. Methods: The data were collected from 183 students by means of self reported questionnaires with clinical competence, satisfaction of clinical practice experience, critical thinking disposition, and self-directed learning, on June 18th 2007 and June 25th 2008. Results: The influencing factors on clinical competence of nursing students were satisfaction of clinical practice experience and critical thinking disposition. The more adaptable a student's major was, the higher the clinical competence and satisfaction of clinical practice experience. The score of self-directed learning was the highest in the well adapted group of a major. For clinical competence categories, the level of basic nursing was the highest followed by psychosocial nursing, patient education, nursing process, monitoring and patient physical assessment. The level of direct nursing care was the lowest among nursing students. Conclusion: In conclusion, results of this study suggest that constructing a cooperative system between colleges and educational hospitals, intensifying preceptors' and professors' clinical instruction, and developing a multimedia learning module and practice using simulators or standardized patient care is necessary to promote clinical competence of nursing students.

• Korean Medical Education Review
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• v.17 no.3
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• pp.122-130
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• 2015

This study evaluated the meaning of the clinical clerkship through in-depth interviews with students who had experienced a clinical clerkship. The clinical clerkship is one of the most important steps in the curriculum for becoming a doctor. While students perform actual clinical practice, the experience also reinforces a great deal of medical knowledge and competence as a reserve doctor. However, departments that operate inefficiently have caused some problems. Therefore, this study analyzed the data from interviews of 25 students who finished the clinical clerkship in terms of the meaning of the clinical clerkship, the attitude of the students toward work in clinical practice, the attitude of professors toward the clinical clerkship, benefits, and drawbacks. Comments are feedback from a student's experience in the clinical clerkship, and they may be an important resource illuminating the current status of clinical practice. This study also discusses how to run an effective clinical clerkship by checking in with students on the problems they face in clinical practice.

• Journal of Korean Academy of Nursing Administration
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• v.12 no.3
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• pp.434-443
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• 2006

Purpose: This study was to compare effects of preceptorship on nursing students' critical thinking propensity, clinical competency, and the satisfaction of clinical practice. Method: The subjects were 80 by preceptorship group and 51 by conventional method group. The data were analyzed by SPSS 12.0 program. Results: The subject's critical thinking propensity, clinical competency and satisfaction of clinical practices between the preceptorship group and the conventional method group revealed statistically significant difference. Subject's critical thinking propensity revealed significant correlations, along with the clinical competεncy and the satisfaction for clinical practice. And the clinical competency revealed statistically significant correlations with the satisfaction for clinical practice. Conclusion: Findings of this study reveals that the nursing students who had clinical practice by preceptorship showed higher scores in the critical thinking propensity, clinical competency, and the satisfaction for clinical practice than the conventional method group. Consequently, we are quite consciously encouraged to reinforce the preceptorship for realization of an effective clinical practice education for nursing students.