• 한국전자통신학회논문지
• /
• 제19권1호
• /
• pp.283-288
• /
• 2024

본 논문에는 장애물들을 극복할 수 있는 새로운 메커니즘을 연구하기 위해 장애물 극복 전 방향(ALL-Direction) 주행 RC 카를 제작하여 여러 가지 장애물이 있는 시험장을 제작해 주행평가를 진행한다. RDS3115 서보모터를 제어하는 알고리즘을 제안하고, 자이로센서를 활용하여 여러 장애물 지형의 기울기를 인식하고 RC 카가 지형을 넘을 수 있는 서보모터의 각도를 조절한다. 시험장 지형 실험에서 제작한 모든 장애물 지형들을 주행하는 데 있어서 가장 적합한 RC 카의 회전 각도를 확인하였다.

• Biomolecules & Therapeutics
• /
• 제21권4호
• /
• pp.307-312
• /
• 2013

Quetiapine is an atypical or second-generation antipsychotic agent and has been a subject of a series of case report and suggested to have the potential for misuse or abuse. However, it is not a controlled substance and is not generally considered addictive. In this study, we examined quetiapine's dependence potential and abuse liability through animal behavioral tests using rodents to study the mechanism of quetiapine. Molecular biology techniques were also used to find out the action mechanisms of the drug. In the animal behavioral tests, quetiapine did not show any positive effect on the experimental animals in the climbing, jumping, and conditioned place preference tests. However, in the head twitch and self-administration tests, the experimental animals showed significant positive responses. In addition, the action mechanism of quetiapine was found being related to dopamine and serotonin release. These results demonstrate that quetiapine affects the neurological systems related to abuse liability and has the potential to lead psychological dependence, as well.

• 한국농업기계학회:학술대회논문집
• /
• 한국농업기계학회 1993년도 Proceedings of International Conference for Agricultural Machinery and Process Engineering
• /
• pp.1186-1195
• /
• 1993

The Japanese type combine harvester has adopted rubber crawlers for the driving mechanism from first production . However, combine harvesters with movable track rollers in the rubber crawler system have been adopted recently for the purpose of stability at the time of climbing over the footpaths between rice fields, as the results of the machines becoming large. However, the dynamic characteristics of movable track rollers have not been clarified. For this reason, the design of movable track rollers depends on trial and errors. It is known that vibration characteristics of the vehicle with movable track rollers are different from the vibration characteristics of the vehicles with fixed track rollers even though the track roller arrangements are the same. Therefore, the theoretical analyses of movable track rollers must be hurried in order to formulate a reasonable track roller arrangement design. the authors have studied the vibration characteristics of the rubber crawler ve icle with fixed track rollers. in this study, the dynamic model of the vehicle with movable track roller sis compared with the dynamic model of the vehicle with fixed track rollers. Next, motions are simulated to analyze the movable track rollers by expanding the motion equation which were constructed for the dynamic model of the fixed track rollers.

• 동의신경정신과학회지
• /
• 제19권2호
• /
• pp.151-163
• /
• 2008

Objective : Recent studies indicate that the deposition of beta-amyloid ($A{\beta}$) is related in the pathogenesis of Alzheimer's disease (AD), but the underlying mechanism is still not clear. Method : To investigate the potential cellular functions of APP and LMK02, we use transgenic drosophila as a model was treated with either LMK02, and the effect in APP expression was determined by climbing assay. LMK02 have been shown to be neuroprotective in fly model systems. We asked whether dietary supplementation with LMK02 would influence behavior and AD-like pathology in a transgenic fly model. Result LMK02 water extract have attenuated fly death in vivo. LMK02-treated fly increased percentage of flight ability more longly and survival ratio more than controls. APP-GRIM drosophila treated with LMK02 had significantly less accumulation of APP deposition in the eye and brain as compared to control drosophila. Conclusion : These results suggest that LMK02 prevent APP-induced neurotoxicity through attenuating flies death induced by APP, and may be useful as potential therapeutic agents for AD.