• Title/Summary/Keyword: Clavosolide A

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Enantioselective Total Synthesis of (-)-Clavosolide A and B

  • Son, Jung-Beom;Kim, Si-Nae;Kim, Na-Yeong;Hwang, Min-Ho;Lee, Won-Sun;Lee, Duck-Hyung
    • Bulletin of the Korean Chemical Society
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    • v.31 no.3
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    • pp.653-663
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    • 2010
  • Enantioselective total synthesis of (-)-clavosolide A and B was reported in full including the synthesis of proposed structure of (-)-clavosoldie A (1), revised structure of (-)-clavosoldie A (5), and revised structure of (-)-clavosoldie B (6). The relative and absolute stereochemistries of the natural products were confirmed unambiguously by comparing the optical rotation values and $^1H$ and $^{13}C$ NMR spectra of them.