• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2535-2537
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• 2016

Background: Most of the cervical cancer patients, including those with cervical adenocarcinomas, come at advanced stage in the developing world so its mortality is high. Radiotherapy is one of the treatment modality for advanced stage cervical adenocarcinomas, but its efficacy depends on several prognostic factors such as the stage, histopathology, presence of organ dysfunction and expression of cellular biology markers mainly involve in cell proliferation such as the epidermal growth factor receptor (EGFR). Some research indicates that activation of EGFR in malignancy (including cervical cancer) correlates with aggressive behavior, a poor prognosis and decreasing sensitivity of radiotherapy. However, the combination between targeted therapies and radiotherapy are innovative approaches which may provide a good result. This study aimed to assess any correlation between expression of EGFR and response to radiotherapy in cervical adenocarcinoma cases. Materials and Methods: A total of 32 women were registered in a retrospective study period January 2007 and May 2014. Paraffin blocks from these patients were processed by classical histological techniques and for immunohistochemical staining of EGFR, scoring being accomplished according to the immunoreactive scoring (IRS) of Remmele and Stegner. Results: Among the studied molecular factors, there was significant correlation expression of EGFR with poor response to radiotherapy (p=0.0001). Conclusions: The result of this study showed a significant correlation between expression of EGFR and sensitivity of radiation in cervical adenocarcinoma cases. Further research is necessary to obtain information about new therapeutic management.

• Journal of Yeungnam Medical Science
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• v.35 no.1
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• pp.63-69
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• 2018

Background: Kinovea software that tracking semi-automatically the motion in video screen has been used to study motion-related tasks in several studies. However, the validation of this software in open field test to assess locomotor activity have not been studied yet. Therefore, this study aimed to examine the reliability and validity of this software in analyzing locomotor activities. Methods: Thirty male Institute Cancer Research mice were subjected in this study. The results examined by this software and the classical method were compared. Test-retest reliability and inter-rater reliability were analyzed with Pearson's correlation coefficient and intraclass correlation coefficient (ICC). The validity of this software was analyzed with Pearson's correlation coefficient. Results: This software showed good test-retest reliability (ICC=0.997, 95% confidence interval [CI]=0.975-0.994, p<0.001). This software also showed good inter-rater reliability (ICC=0.987, 95% CI=0.973-0.994, p<0.001). Furthermore, in three analyses for the validity of this software, there were significant correlations between two methods (Pearson's correlation coefficient=0.928-0.972, p<0.001). In addition, this software showed good reliability and validity in the analysis locomotor activity according to time interval. Conclusion: This study showed that this software in analyzing drug-induced locomotor activity has good reliability and validity. This software can be effectively used in animal study using the analysis of locomotor activity.

• Structural Engineering and Mechanics
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• v.20 no.4
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• pp.477-493
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• 2005

In case of Mindlin plate, not only the bending deformation but also the shear behavior is allowed. While the bending and shear stiffness are given in the same order in terms of elastic modulus, they are in different order in case of plate thickness. Accordingly, bending and shear contributions have to be dealt with independently if the stochastic finite element analysis is performed on the Mindlin plate taking into account of the uncertain plate thickness. In this study, a formulation is suggested to give the response variability of Mindlin plate taking into account of the uncertainties in elastic modulus as well as in the thickness of plate, a geometrical parameter, and their correlation. The cubic function of thickness and the correlation between elastic modulus and thickness are incorporated into the formulation by means of the modified auto- and cross-correlation functions, which are constructed based on the general formula for n-th joint moment of random variables. To demonstrate the adequacy of the proposed formulation, a plate with various boundary conditions is taken as an example and the results are compared with those obtained by means of classical Monte Carlo simulation.

• The Korean Journal of Applied Statistics
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• v.22 no.6
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• pp.1143-1152
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• 2009

A canonical correlation analysis(CCA)-based method is proposed for prediction of future climate change which combines information from ensembles of atmosphere-ocean general circulation models(AOGCMs) and observed climate values. This paper focuses on predictions of future climate on a regional scale which are of potential economic values. The proposed method is obtained by coupling the classical CCA with empirical orthogonal functions(EOF) for dimension reduction. Furthermore, we generate a distribution of climate responses, so that extreme events as well as a general feature such as long tails and unimodality can be revealed through the distribution. Results from real data examples demonstrate the promising empirical properties of the proposed approaches.

• Journal of the Korean Applied Science and Technology
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• v.27 no.4
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• pp.452-460
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• 2010

Any theory of liquid should account for interactions between molecules, since molecules in a liquid are close to each other. For this matter statistical-mechanical methodology has been used and various models have been proposed on the basis of this methodology. Among them Kirkwood-Buff solution theory has attracted a lot of interest, because it is regarded as being the most powerful. In this article Kirkwood-Buff solution theory is revisited and its key equations are derived. On the way to these equations, the concepts of pair correlation function, radial distribution function, Kirkwood-Buff integration are explained and implemented. Since complexity of statical mechanics involved in this theory, the equations are applied to one-component systems and the results are compared to those obtained by classical thermodynamics. This may be a simple way for Kirkwood-Buff solution theory to be examined for its validity.

• Proceedings of the KIEE Conference
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• 1999.07g
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• pp.2821-2823
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• 1999

In this paper we proposed an algorithm for rotation-invariant pattern recognition and rotated angle estimation between two patterns by employing selective template matching. Generally template matching has been used in determining the location of pattern but template matching requires a number of calculating correlation. To reduce the number of correlation we used steady-state genetic algorithm which is effective in optimization problem. We apply this method to distinguish specific pattern from similar coin patterns and estimate rotated angle between patterns. Our result leads us to the conclusion that proposed method performed faster than classical template matching

• Journal of the Korean Physical Society
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• v.73 no.9
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• pp.1315-1323
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• 2018

The classical-fluids density functional theory has been developed for studying the structural and the electrical properties of electrolyte solutions containing uniformly charged hard-spherical ions. The modified fundamental-measure theory has been used to evaluate the hard-sphere contribution. The mean-field approximation has been employed to calculate the cross correlation between the hard sphere contribution and the Coulomb interaction. The Poisson equation for ions carrying charges that are spatially separated has been solved. The present theory shows reasonably good agreement with the corresponding Monte Carlo simulation results. The calculated results show that the attraction between like-charged planar surfaces is the result of the intra-ionic correlation and depends strongly on the ion size, valence, mole fraction, and charge distribution of electrolytes.

• International Journal of Internet, Broadcasting and Communication
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• v.15 no.3
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• pp.43-51
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• 2023

Slotted ALOHA (S-ALOHA) is a classical medium access control protocol widely used in multiple access communication networks, supporting distributed random access without the need for a central controller. Although stability and delay have been extensively studied in existing works, most of these studies have assumed ideal channel conditions or independent fading, and the impact of time-correlated wireless channels has been less addressed. In this paper, we investigate the queueing delay performance in S-ALOHA networks under time-correlated channel conditions by utilizing a Gilbert-Elliott model. Through simulation studies, we demonstrate how temporal correlation in the wireless channel affects the queueing delay performance. We find that stronger temporal correlation leads to increased variability in queue length, a larger probability of having queue overflows, and higher congestion levels in the S-ALOHA network. Consequently, there is an increase in the average queueing delay, even under a light traffic load. With these findings, we provide valuable insights into the queueing delay performance of S-ALOHA networks, supplementing the existing understanding of delay in S-ALOHA networks.

• Journal of Korea Water Resources Association
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• v.37 no.3
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• pp.233-240
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• 2004

Most of hydrological analyses in the field of water resources are launched by gathering and analyzing rainfall data. Several methods have been developed to estimate areal rainfall from point rainfall data and to fill missing or ungaged data. Thiessen and Reciprocal Distance Squared(RDS) methods whose parameters are only dependent on inter-station distance are classical work in hydrology, but these techniques do not provide a continuous representation of the hydrologic process involved. In this study, kriging technique was applied to rainfall analysis in Nakdong river basin in order to complement the defects of these classical methods and to reflect spatial characteristics of regional rainfall. After spatial correlation and semi-variogram analyses were performed to perceive regional rainfall property, kriging analysis was performed to interpolate rainfall data for each grid Thus, these procedures were enable to estimate average rainfall of subbasins. In addition, poor region of rainfall observation was analyzed by spatial interpolation error for each grid and mean error for each subbasin.

• The Korea Journal of Herbology
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• v.37 no.2
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• pp.13-21
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• 2022

Objectives : The evaluation of academic achievement is pivotal for establishing accurate direction and adequate level of medical education. The purpose of this study was to firstly establish innovative item analysis technique of Item Response Theory (IRT) for analyzing multiple-choice test of herbology in the traditional Korean medicine education which has not been available for the difficulty of test theory and statistical calculation. Methods : The answers of 390 students (2012-2018) to the 14 item herbology test in college of Korean medicine were used for the item analysis. As for the multidimensional analysis of item characteristics, difficulty, discrimination, and guessing parameters along with item-total correlation and percentage of correct answer were calculated using Classical Test Theory (CTT) and IRT. Results : The validity parameters of strong and weak items were illustrated in multiple perspectives. There were 4 items with six acceptable index scores, and 5 items with only one acceptable index score. The item discrimination of IRT was found to have no significant correlation with difficulty and discrimination indices of CTT emphasizing attention of professionals of medical education as for the test credibility. Conclusion : The critical suggestions for the development, utilization and revision of test items in the e-learning and evidence-based Teaching era were made based on the results of item analysis using IRT. The current study would firstly provide foundation for upgrading the quality of Korean medicine education using test theory.