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Examining Mathematics Teachers' Intentions regarding Formative Assessment (수학 수업 지도안에 나타난 교사가 설계하는 형성평가 분석)

  • Lee, DaEun;Kim, Gooyeon
    • Communications of Mathematical Education
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    • v.35 no.4
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    • pp.527-546
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    • 2021
  • The purpose of this study is to reveal what mathematics teachers focus on and how they assess students' thinking during lessons enacted. For this purpose, we googled and searched internet sites to collect formative assessment materials for the year 2014 to 2019. The formative assessment tasks data were analyzed according to the levels cognitive demand levels and tasks suggested in textbooks in terms of degrees to which how they are related. The data analysis suggested as follows: a) most of the formative assessment tasks were at the low-level, in particular, PNC level tasks that require applying particular procedures without connections to concepts and meaning underlying the procedures, b) the assessment tasks appeared to be very similar to the tasks suggested in the secondary mathematics textbooks, and c) it seemed that 3 types of formative assessment, observation notes, self-assessment, and peer-assessment were dominantly utilized during mathematics lessons and these different types of formative assessment were employed apparently to find out whether students participated actively in class and in group activity, not how they go through understanding or thinking processes.

MHY2251, a New SIRT1 Inhibitor, Induces Apoptosis via JNK/p53 Pathway in HCT116 Human Colorectal Cancer Cells

  • Yong Jung Kang;Young Hoon Kwon;Jung Yoon Jang;Jun Ho Lee;Sanggwon Lee;Yujin Park;Hyung Ryong Moon;Hae Young Chung;Nam Deuk Kim
    • Biomolecules & Therapeutics
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    • v.31 no.1
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    • pp.73-81
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    • 2023
  • Sirtuins (SIRTs) belong to the nicotinamide adenine dinucleotide (NAD+)-dependent class III histone deacetylase family. They are key regulators of cellular and physiological processes, such as cell survival, senescence, differentiation, DNA damage and stress response, cellular metabolism, and aging. SIRTs also influence carcinogenesis, making them potential targets for anticancer therapeutic strategies. In this study, we investigated the anticancer properties and underlying molecular mechanisms of a novel SIRT1 inhibitor, MHY2251, in human colorectal cancer (CRC) cells. MHY2251 reduced the viability of various human CRC cell lines, especially those with wild-type TP53. MHY2251 inhibited SIRT1 activity and SIRT1/2 protein expression, while promoting p53 acetylation, which is a target of SIRT1 in HCT116 cells. MHY2251 treatment triggered apoptosis in HCT116 cells. It increased the percentage of late apoptotic cells and the sub-G1 fraction (as detected by flow cytometric analysis) and induced DNA fragmentation. In addition, MHY2251 upregulated the expression of FasL and Fas, altered the ratio of Bax/Bcl-2, downregulated the levels of pro-caspase-8, -9, and -3 proteins, and induced subsequent poly(ADP-ribose) polymerase cleavage. The induction of apoptosis by MHY2251 was related to the activation of the caspase cascade, which was significantly attenuated by pre-treatment with Z-VAD-FMK, a pan-caspase inhibitor. Furthermore, MHY2251 stimulated the phosphorylation of c-Jun N-terminal kinase (JNK), and MHY2251-triggered apoptosis was blocked by pre-treatment with SP600125, a JNK inhibitor. This finding indicated the specific involvement of JNK in MHY2251-induced apoptosis. MHY2251 shows considerable potential as a therapeutic agent for targeting human CRC via the inhibition of SIRT1 and activation of JNK/p53 pathway.

Validation of the effectiveness of AI-Based Personalized Adaptive Learning: Focusing on basic math class cases (인공지능(AI) 기반 맞춤형 학습의 효과검증: 기초 수학수업 사례 중심으로)

  • Eunae Burm;Yeol-Eo Chun;Ji Youn Han
    • Journal of Internet of Things and Convergence
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    • v.9 no.3
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    • pp.35-43
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    • 2023
  • This study tried to find out the applicability and effectiveness of the AI-based adaptive learning system in university classes by operating an AI-based adaptive learning system on a pilot basis. To this end, an AI-based adaptive learning system was applied to analyze the operation results of 42 learners who participated in basic mathematics classes, and a survey and in-depth interviews were conducted with students and professors. As a result of the study, the use of an AI-based customized learning system improved students' academic achievement. Both instructors and learners seem to contribute to improving learning performance in basic concept learning, and through this, the AI-based adaptive learning system is expected to be an effective way to enhance self-directed learning and strengthen knowledge through concept learning. It is expected to be used as basic data related to the introduction and application of basic science subjects for AI-based adaptive learning systems. In the future, we suggest a strategy study on how to use the analyzed data and to verify the effect of linking the learning process and analyzed data provided to students in AI-based customized learning to face-to-face classes.

Exploring Factors Influencing Affective Characteristics in Elementary School Students: Focusing on School Mathematics Education and Social Environment (초등학생의 정의적 특성에 영향을 미치는 요인 탐색: 학교에서의 수학 교육 및 사회적 환경을 중심으로)

  • Kwon, Jeom-Rae;Kwon, Misun
    • Education of Primary School Mathematics
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    • v.26 no.3
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    • pp.199-217
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    • 2023
  • Affective characteristics have been consistently emphasized in mathematics education, but students' confidence or interest in mathematics has not changed significantly. This study analyzes the factors affecting the affective characteristics according to students' academic achievements, which have not been studied so far. The study was surveyed 593 students in the 5th and 6th grades, divided into school mathematics education and social-environmental factors. As a result of the study, students cited 'mathematics class at school' as the factor that had the most influence on their affective characteristics, regardless of academic achievement. Excluding 'mathematics classes at school', upper level students said that 'private education' and 'college entrance exams and jobs', had the most influence on their affective characteristics. Middle level students said that 'assessment at school' and 'private education' had the most influence on their affective characteristics. Lower-level students said that 'school evaluation' and 'mathematics textbook' had the most influence on the affective characteristics. In particular, as the academic achievement level decreased, students' participation in classes decreased rapidly. Most students said that the mathematics content they were learning was too difficult for that reason. Considering these research results, it would be effective to apply methods according to students' academic achievement to some extent in order to improve affective characteristics.

Properties on the Strength of Polymer Concrete Using Nano MMT-UP Composite (나노 MMT-폴리머 복합체를 이용한 폴리머 콘크리트의 강도 특성)

  • Jo, Byung-Wan;Moon, Rin-Gon;Park, Seung-Kook
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.4A
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    • pp.761-766
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    • 2006
  • Polymer composite are increasingly considered as structural components for use in civil engineering, on account of their enhanced strength-to-weight ratios. Unsaturated polyester (UP) resin have been widely used for the matrix of composites such as FRP and polymer composite, due to its excellent adhesive. Polymer nanocomposites are new class of composites derived from the nano scale inorganic particles with dimensions typically in the range of 1 to 1000 nm that are dispersed in the polymer matrix homogeneously. Owing to the high aspect ratio of the fillers, mechanical, thermal, flame, retardant and barrier properties are enhanced without significant loss of clarity, toughness or impact strength. To prepare the MMT (Montmorillonite)-UP exfoliated nanocomposites, UP was mixed with MMT at $60^{\circ}C$ for 3 hours by using pan mixer. XRD (X-ray diffraction) pattern of the composites and TEM (Transmission Electron Micrographs) showed that the interlayer spacing of the modified MMT were exfoliated in polymer matrix. The mechanical properties also supported these findings, since in general, tensile strength, modulus with modified MMT were higher than those of the composites with unmodified MMT. The thermal stability of MMT-UP nanocomposite is better than that of pure UP, and its glass transition temperature is higher than that of pure UP. The polymer concrete made with MMT-UP nanocomposite has better mechanical properties than of pure UP. Therefore, it is suggested that strength and elastic modulus of polymer concrete was found to be positively tensile strength and tensile modulus of the MMT-UP nanocomposites.

Experimental Study to Evaluate the Durability of 100 MPa Class Ultra-high Strength Centrifugal Molding Concrete (100MPa급 초고강도 원심성형 콘크리트의 내구성 평가를 위한 실험연구)

  • Jeong-Hoi Kim;Sung-Jin Kim;Doo-Sung Lee
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.28 no.1
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    • pp.12-23
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    • 2024
  • In this study, a structural concrete square beam was developed using the centrifugal molding technique. In order to secure the bending stiffness of the cross section, the hollow rate of the cross section was set to 10% or less. Instead of using the current poor mixture of concrete and a concrete mixing ratio with a high slump (150-200) and a design strength of 100 MPa or more was developed and applied. In order to investigate the durability of centrifugally formed PSC square beams to be used as the superstructure of the avalanch tunnel or ramen bridge, the durability performance of ultra-high-strength centrifugally formed concrete with a compressive strength of 100 MPa was evaluated in terms of deterioration and chemical resistance properties.Concrete durability tests, including chloride penetration resistance, accelerated carbonation, sulfate erosion resistance, freeze-thaw resistance, and scaling resistance, were performed on centrifugally formed square beam test specimens produced in 2022 and 2023. Considering the information verified in this study, the durability of centrifugally molded concrete, which has increased watertightness in the later manufacturing stage, was found to be superior to that of general concrete.

An analysis of the implementation plans for ensuring basic academic abilities in mathematics (수학 교과의 기초학력 보장과 관련된 시·도 교육청의 시행계획 분석)

  • Oh, MinYoung;You, EunJung;Pang, JeongSuk
    • Education of Primary School Mathematics
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    • v.27 no.2
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    • pp.173-185
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    • 2024
  • Mathematics is a subject that is closely related to ensuring basic academic abilities. As the importance of basic academic abilities has emerged recently, various policies and programs have been implemented to ensure basic academic abilities in mathematics. In this study, we extracted the programs related to mathematics from the Implementation Plans of the Basic Academic Abilities Guarantee of 17 city and provincial education departments and analyzed the actual status of the programs. We divided the programs into diagnosis and support. Regarding diagnosis, we analyzed what types of diagnostic tools are used, who chooses diagnostic tools, who is diagnosed, and when students are diagnosed. Regarding support, we classified it as in-class, in-school, and out-of-school support, and further analyzed the type of the learning support program and the expertise of the instructor. The results of this study showed that there was room for improvement in the timing of diagnosis and diagnostic expertise. This study also found the problems with the lack of preventive programs, ensuring teacher expertise, and support for dyscalculia. This study is expected to contribute to the implementation of programs to ensure basic academic abilities in mathematics and to promote research on basic academic abilities in mathematics education.

Kepler's Scientific Problem Finding and the Abductive Reasoning in his Discovery of the Retinal Image Formation (Kepler의 망막 상 이론 형성 과정에서의 과학적 문제 발견과 귀추적 사고)

  • Kim, Young-Min
    • Journal of The Korean Association For Science Education
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    • v.26 no.7
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    • pp.835-842
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    • 2006
  • The aims of this study are to investigate how Kepler found a scientific problem for the retinal image theory and how abductive reasoning was used in his theory development, and to find implications for teaching creativity in science class from his thinking processes in the scientific discovery. Through the analysis of the related literatures, it was found that Kepler's problem finding in his retinal image theory came from the critical analysis of contemporary theories of vision, based on his relevant knowledge of optics, as he formulated his own hypothesis to build a new theory in eye vision employing optical phenomenon in spherical lens, which is a kind of abductive reasoning. From the results, three suggestions are proposed, that: (a) in the development of creativity teaching material, the situations like Kepler's problem finding need to be included in the programs; (b) it should be taught that relevant scientific knowledge is important for problem finding and hypothesis formulating; and (c) the experience of successful problem solving by themselves could help them find new scientific problem(s).

A Case of Developing Performance Evaluation Model for Korean Defense Informatization (국방정보화 수준평가 모델 개발 사례)

  • Gyoo Gun Lim;Dae Chul Lee;Hyuk Jin Kwon;Sung Rim Cho
    • Information Systems Review
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    • v.19 no.3
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    • pp.23-45
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    • 2017
  • The ROK military is making a great effort and investment in establishing network-centric warfare, a future battlefield concept, as a major step in the establishment of a basic plan for military innovation. In the military organization level, an advanced process is introduced to shorten the command control time of the military and the business process is improved to shorten the decision time. In the information system dimension, an efficient resource management is achieved by establishing an automated command control system and a resource management information system by using the battle management information system. However, despite these efforts, we must evaluate the present level of informatization in an objective manner and assess the current progress toward the future goal of the military by using objective indicators. In promoting informatization, we must systematically identify the correct areas of improvement and identify policy directions to supplement in the future. Therefore, by analyzing preliminary research, workshops, and expert discussions on the major informatization level evaluation models at home and abroad, this study develops an evaluation model and several indicators that systematically reflect the characteristics of military organizations. The developed informatization level evaluation model is verified by conducting a feasibility test for the troops of the operation class or higher. We expect that this model will be able to objectively diagnose the level of informatization of the ROK military by putting budget and resources into the right place at the right time and to rapidly improve the vulnerability of the information sector.

Characteristics and classification of paddy soils on the Gimje-Mangyeong plains (김제만경평야(金堤萬頃平野)의 답토양특성(沓土壤特性)과 그 분류(分類)에 관(關)한 연구(硏究))

  • Shin, Yong Hwa
    • Korean Journal of Soil Science and Fertilizer
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    • v.5 no.2
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    • pp.1-38
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    • 1972
  • This study, designed to establish a classification system of paddy soils and suitability groups on productivity and management of paddy land based on soil characteristics, has been made for the paddy soils on the Gimje-Mangyeong plains. The morphological, physical and chemical properties of the 15 paddy soil series found on these plains are briefly as follows: Ten soil series (Baeggu, Bongnam, Buyong, Gimje, Gongdeog, Honam, Jeonbug, Jisan, Mangyeong and Suam) have a B horizon (cambic B), two soil series (Geugrag and Hwadong) have a Bt horizon (argillic B), and three soil series (Gwanghwal, Hwagye and Sindab) have no B or Bt horizons. Uniquely, both the Bongnam and Gongdeog series contain a muck layer in the lower part of subsoil. Four soil series (Baeggu, Gongdeog, Gwanghwal and Sindab) generally are bluish gray and dark gray, and eight soil series (Bongnam, Buyong, Gimje, Honam, Jeonbug, Jisan, Mangyeong and Suam) are either gray or grayish brown. Three soil series (Geugrag, Hwadong and Hwagye), however, are partially gleyed in the surface and subsurface, but have a yellowish brown to brown subsoil or substrata. Seven soil series (Bongnam, Buyong, Geugrag, Gimje, Gongdeog, Honam and Hwadong) are of fine clayey texture, three soil series (Baeggu, Jeonbug and Jisan) belong to fine loamy and fine silty, three soil series (Gwanghwal, Mangyeong and Suam) to coarse loamy and coarse silty, and two soil series (Hwagye and Sindab) to sandy and sandy skeletal texture classes. The carbon content of the surface soil ranges from 0.29 to 2.18 percent, mostly 1.0 to 2.0 percent. The total nitrogen content of the surface soil ranges from 0.03 to 0.25 percent, showing a tendency to decrease irregularly with depth. The C/N ratio in the surface soil ranges from 4.6 to 15.5, dominantly from 8 to 10. The C/N ratio in the subsoil and substrata, however, has a wide range from 3.0 to 20.25. The soil reaction ranges from 4.5 to 8.0. All soil series except the Gwanghwal and Mangyeong series belong to the acid reaction class. The cation exchange cpacity in the surface soil ranges from 5 to 13 milliequivalents per 100 grams of soil, and in all the subsoil and substrata except those of a sandy texture, from 10 to 20 milliequivalents per 100 grams of soil. The base saturation of the soil series except Baeggu and Gongdeog is more than 60 percent. The active iron content of the surface soil ranges from 0.45 to 1.81 ppm, easily-reduceable manganese from 15 to 148 ppm, and available silica from 36 to 366 ppm. The iron and manganese are generally accumulated in a similar position (10 to 70cm. depth), and silica occurs in the same horizon with that of iron and manganese, or in the deeper horizons in the soil profile. The properties of each soil series extending from the sea shore towards the continental plains change with distance and they are related with distance (x) as follows: y(surface soil, clay content) = $$-0.2491x^2+6.0388x-1.1251$$ y(subsoil or subsurface soil, clay content) = $$-0.31646x^2+7.84818x-2.50008$$ y(surface soil, organic carbon content) = $$-0.0089x^2+0.2192x+0.1366$$ y(subsoil or subsurface soil, pH) = $$-0.0178x^2-0.04534x+8.3531$$ Soil profile development, soil color, depositional and organic layers, soil texture and soil reaction etc. are thought to be the major items that should be considered in a paddy soil classification. It was found that most of the soils belonging to the moderately well, somewhat poorly and poorly drained fine and medium textured soils and moderately deep fine textured soils over coarse materials, produce higher paddy yields in excess of 3,750 kg/ha. and most of the soils belonging to the coarse textured soils, well drained fine textured soils, moderately deep medium textured soils over coarse materials and saline soils, produce yields less than 3,750kg/ha. Soil texture of the profile, available soil depth, salinity and gleying of the surface and subsurface soils etc. seem to be the major factors determining rice yields, and these factors are considered when establishing suitability groups for paddy land. The great group, group, subgroup, family and series are proposed for the classification categories of paddy soils. The soil series is the basic category of the classification. The argillic horizon (Bt horizon) and cambic horizon (B horizon) are proposed as two diagnostic horizons of great group level for the determination of the morphological properties of soils in the classification. The specific soil characteristics considered in the group and subgroup levels are soil color of the profile (bluish gray, gray or yellowish brown), salinity (salic), depositonal (fluvic) and muck layers (mucky), and gleying of surface and subsurface soils (gleyic). The family levels are classified on the basis of soil reaction, soil texture and gravel content of the profile. The definitions are given on each classification category, diagnostic horizons and specific soil characteristics respectively. The soils on these plains are classified in eight subgroups and examined under the existing classification system. Further, the suitability group, can be divided into two major categories, suitability class and subclass. The soils within a suitability class are similar in potential productivity and limitation on use and management. Class 1 through 4 are distinguished from each other by combination of soil characteristics. Subclasses are divided from classes that have the same kind of dominant limitations such as slope(e), wettness(w), sandy(s), gravels(g), salinity(t) and non-gleying of the surface and subsurface soils(n). The above suitability classes and subclasses are examined, and the definitions are given. Seven subclasses are found on these plains for paddy soils. The classification and suitability group of 15 paddy soil series on the Gimje-Mangyeong plains may now be tabulated as follows.

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