• The Korean Journal of Physiology and Pharmacology
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• 제22권5호
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• pp.597-605
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• 2018

In this study, we demonstrated the inhibitory effect of the Class Ic antiarrhythmic agent propafenone on voltage-dependent $K^+$ (Kv) channels using freshly isolated coronary artery smooth muscle cells from rabbits. The Kv current amplitude was progressively inhibited by propafenone in a dose-dependent manner, with an apparent $IC_{50}$ value of $5.04{\pm}1.05{\mu}M$ and a Hill coefficient of $0.78{\pm}0.06$. The application of propafenone had no significant effect on the steady-state activation and inactivation curves, indicating that propafenone did not affect the voltage-sensitivity of Kv channels. The application of train pulses at frequencies of 1 or 2 Hz progressively increased the propafenone-induced inhibition of the Kv current. Furthermore, the inactivation recovery time constant was increased after the application of propafenone, suggesting that the inhibitory action of propafenone on Kv current is partially use-dependent. Pretreatment with Kv1.5, Kv2.1 or Kv7 inhibitor did not change the inhibitory effect of propafenone on the Kv current. Together, these results suggest that propafenone inhibits the vascular Kv channels in a dose- and use-dependent manner, regardless of $Na^+$ channel inhibition.

• 대한약침학회지
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• 제6권3호
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• pp.57-63
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• 2003

Background : This study was to investigate existing studies on the mushroom Phellinus linteus for possible applications in treating hard to cure diseases and uses in herbal acupuncture as the above is known to have an anti-cancer effects and stimulating the immune system. Results : Based on the literary consideration, the following results were obtained : 1. Proteins and polysaccharides of the Class Basidiomycetes activate the host immune system for anti-cancer action without known side effects, thus it can be given for the prevention and treatment of cancer as a supplement. Phellinus linteus mushroom showed the most significant effects. 2. The Phellinus linteus mushroom is a fungi in the family Hymenochaetaceae and Phellinus, under the class Basidiomycetes. Phellinus linteus can be often found on the trunk of mulberry trees and other latifoliate trees. 3. The characteristics of Phellinus linteus are sweet, neutral in temperature, non-toxic, dissipate the stagnated blood, stop bleeding, invigorate the blood circulation and remove stasis, and nourish qi. It has been used for treating continuous menstrual discharge among the female patients and removing masses in the abdomen to name a few. 4. Phellinus linteus contains agaric acid, fatty acid, C23 and other numerous enzymes. 5. Phellinus linteus is known to have anti-cancer and anti-oxidant effects, stimulation of the immune system, as well as anti-inflammatory effects, inhibition of angiogenesis, and analgesic actions.

• 한국정보처리학회논문지
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• 제4권5호
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• pp.1257-1266
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• 1997

객체지향 언어가 가지고 있는 다양한 개념은 강력한 프로그램 구현을 지원할 수 있다. 그러나 이러한 개념에는 복잡한 이벤트의 관련성에 의해 프로그램의 분석과 이해에 어려움을 가지고 있다. 특히 객체지향 언어의 정적인 면보다는 동적인 측련의 이해를 어렵게 한다. 동적인 면은 클래스간 이벤트 작용을 인식하므로서 이해를 지원한다. 따라서 본 논문에서는 객체지향 프로그램의 이해를 지원할 수 있도록 이벤트 추상화 표현을 제시한다. 또한 클래스터링 개념을 이벤트 추상화에 적용하여, 객체지향 언어의 이해를 용이하게 지원할 수 있도록 이벤트 추상화 표현과 이벤트 추상화에 적용될 클러스터링 개념을 제시한다. 이벤트의 클래스터링에 의해서 사용 자는 클래스의 기능성 정보와 클래스 라이브러리 검색시 선택된 클래스와 이벤트 상호 작용 관계가 있는 다른 클래스를 파악함으로서 클래스 검색의 효율성을 지원한다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2011년도 추계학술대회
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• pp.371-374
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• 2011

UML은 객체지향 개념을 매우 잘 설명하고 있으며 요구 분석 단계에서 시스템 기능을 분석하기 위한 유스케이스 다이어그램과 도메인의 객체들을 개념적으로 표현한 클래스 다이어그램을 지원하고 있으며, 설계 단계에서 클래스 내부적인 연결을 보기 위한 시퀀스 다이어그램을 지원한다. 객체지향을 지원하는 대표적인 비주얼 기반 언어인 LabVIEW OOP는 직관적인 설계 도구로서 설계와 동시에 실행할 수 있는 개발 도구이다. 그러나, LabVIEW OOP 역시 시스템 개발자가 시스템을 설계하기 위해 설계 단계에서 객체지향 개념을 잘 표현하고 이해할 수 있는 방법이 필요하다. 논문에서는 객체지향 개념을 표현하는 UML을 이용하여 설계된 모델링을 LabVIEW OOP로 설계 시에 적용 가능한 기법을 제안한다.

• 한국콘텐츠학회논문지
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• 제16권11호
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• pp.38-52
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• 2016

본 연구는 폴리텍대학 NCS 직업기초능력 수업에서 액션러닝방식이 학습자의 학습동기 증진과 문제해결력 향상에 미치는 영향을 분석하였다. 이를 위해 충남소재 B폴리텍대학 학생들을 연구대상으로 하였고 연구방법은 실험연구로써 실험집단 53명을 대상으로 액션러닝방식을 적용하였고 통제집단 64명을 대상으로 직접교수방식을 적용하였다. 자료 분석은 기술통계분석과 학습동기 및 문제해결력의 하위요인에 대한 다변량분산분석(MANOVA)을 실시하였다. 그 결과 학습동기의 하위요인 중 관련성, 자신감, 만족감에서 액션러닝방식의 학습효과가 높게 나타났고 문제해결력의 하위요인 중 문제명료화, 원인분석, 대안개발, 계획/실행, 수행평가에서 액션러닝방식의 학습효과가 높게 나타났다. 뿐만 아니라 액션러닝 방식의 학습은 과제중심의 팀 학습을 하는 과정에서 다양한 관점에 대한 이해, 의사소통, 리더십, 대인관계, 자기개발, 갈등관리, 회의운영 방법 등을 자연스럽게 터득하면서 직업기초능력을 함양할 수 있기 때문에 폴리텍대학 NCS 직업기초능력 수업의 교수학습방법으로 활용이 요구된다.

• 한국과학교육학회지
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• 제16권4호
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• pp.340-350
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• 1996

Knowledge is composed through the interaction between the concept structure already held by students and their experience, and learning can be said to be the active process of solving the cognitive conflict caused by this interaction. Therefore, this study consists in showing the effective learning method and finding out the elements which the teacher has to own, through examining several forms of pre-conception or mis-conception of the inertia, the force-equilibrium, the action and reaction, the heat, and the electric current, and then finding out their solution and studying student's change in science concepts. For this study, the types of concept on the five above-mentioned materials which students have were examined through the concept-classifying question paper, and the classes to which the class mode for the change of concepts applied, were practised in each different classroom by each different instructor - a professor, a scientist, a teacher, and two students, respectively. And the effect of the teaching strategy based on these classes, and each different instructor' influence on the change of concept in students. were examined. The result of my study is as follows; 1. Students have various types of pre-conception which are different from science concept, and these types of pre-conception tend to last even after learning in class. 2. The thoughts on the correct science concept of the high school third-grade students who learned the physics in the traditional teaching method, and the second grade students who don't learn the physics yet, were nearly equal those of the second grade students by receiving the physics class through the cognitive conflict course were greatly changed especially that students showed the distinct change on mechanics and electric current. 3. Students didn't show the remarkable change of the science concept on the five materials in the four kinds of experimental classes by each different instructor but in the part of mechanics, there was the distinct change between the class by professor and those by the students. This was due to the difference of the authority and the attitude of the concept demonstrator. 1) The authority, the kind attitude, and the responsibility of the expert played an important role in the correct concept-formation of mechanics part - especially in the case of the mis-conception caused by the intuitive belief. 2) In the class by instructor with the democratic teaching method, the change of concept took place more easily, because in his class students could discuss the subject freely, so that they might experience the thought course to give them the confidence on the science concept.

• 한국게임학회 논문지
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• 제12권1호
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• pp.113-122
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• 2012

본 연구에서는 음악게임을 활용한 음악 감상 교육의 효과 및 만족도를 살펴보았다. 이를 위해 경기도 G초등학교 4학년 남녀학생 107명을 대상으로 실험을 실시하였다. 연구결과 음악 게임을 활용한 수업이 음악 감상을 한 수업보다 학습평가와 학습몰입도에 있어서 높게 나타났고, 특히 만족도에서는 확연히 높은 결과가 나타났다. 또한 학습몰입도와 학습만족도는 학습평가에 영향을 미치는 것으로 분석되었다. 본 연구 결과는 스마트 기기를 학교 정규 수업에 적용하여 학습 콘텐츠 설계 방향을 제시하는데 기여할 것으로 본다.

• 복식
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• 제56권8호
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• pp.15-34
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• 2006

Knit wear was industrialized, diversified, specialized and was made into high-class and it is including knitted cloth and small product for fashion as well as cardigan, sweater, and jacket etc. unlike past recognition only with underwear and inner wear. To consider elasticity to be the best strength of knit wear, middle-aged women that form change is serious are wearing knit wear as clothes for going out, and this may be regarded as clothes action to be conscious of form than vogue. Thus, in this study, this researcher tried to suggest solution scheme through the development of design of knit wear to supplement the form defect of middle-aged women. This researcher tried to develop the design of knit wear to supplement the form defect of middle-aged women, after examining the theoretical background of knit wear, the bodily and mental feature of middle-aged women. Internal and external knit wear brand that middle-aged women prefer as the scheme for solving the problematic form of middle-aged women with knit wear. As the result first, to see the present situation of inland production enterprise of knit wear, almost all the brand companies are concentrating energies on widening age class. Second, middle-aged women become far off from the form which is regarded ideal form in modern society. Third, result that this researcher examined the brand of knit wear of middle-aged women is as follows : MORADO, Cartknit, Escalier. And, in foreign knit wear brand, ST John, Missoni, ESCADA. Fourth, as the result that this researcher did work manufacture for the supplement of form defect of middle-aged women, it has practical and active side, and off-time has high-class and elegant refined beauty.

• 정보과학회 논문지
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• 제43권10호
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• pp.1079-1084
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• 2016

단일상태파싱오토마톤은 구문 분석할 때 행동의 결정이 현재 상태로만 가능하다는 특징이 있고, LR오토마톤과 비교하여 상태수가 적고 구문 분석 시간이 단축된다는 장점이 있다. 한편 단일 상태파싱오토마톤은 적용 가능한 문법 클래스가 LR문법보다 작다는 단점이 있다. 본 논문에서는 단일상태파싱오토마톤을 LR문법 클래스에 적용 가능하도록 확장하는 방법을 제시한다. 기존 방법에서는 파싱오토마톤 생성 과정에서 싸이클릭 상태가 생성되는 경우에 대한 처리 방법을 제시하지 못하였다. 본 논문은 싸이클릭 상태에 대한 입력스트링에 따른 동적 처리 작업을 제시하여, 싸이클릭 상태에 대한 문제를 해결한다. 본 논문에서 확장한 방법은 모든 LR 문법에 대해 단일상태파싱오토마톤을 생성할 수 있게 한다.

• 교육시설 논문지
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• 제18권3호
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• pp.3-11
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• 2011

This study aims at proposing some reform measures for the middle school grouping system in Gwangju Metropolitan City, which is divided 86 middle schools into 10 clusters and 3 school districts. In doing so, it analyzes the present status of educational environment and student walking distance in each school district such as the number of student per teacher, the student density, the school size and the gender ratio in class. And it conducts a survey of 5,363 middle school students, 3,966 parents and 1,007 teachers, also evaluates their satisfaction levels and needs with the student allocation system. As the result of the survey and data analysis, it finds out some problems in some school districts which are gender imbalance in class, the preference for private middle schools and inconvenience in commuting to school. To solve these problems, the study suggests the better alternatives to replace the current system. Firstly, to set up the basic fundamental principles detailed in 3 action plan, which emphasize the adherence to a close-range allocation, the appropriate size of school and class, and the equalization of educational environment. Secondly, to establish the information system for managing the school district in order to be more objective and transparent. Finally, it gives a concrete proposal which divides the 10th school grouping system into the 11th. The result would be expected to ease the gender imbalance and the concentration of private middle schools, to improve the student walking condition to school.