• 제목/요약/키워드: Circulation Pump

검색결과 226건 처리시간 0.026초

한국산 잡견에서 백혈구 제거 충진액이 체외순환 중 위점막 이산화탄소 농도와 IL-8 수준에 미치는 영향 (The Effects of Leukocyte Depleted Priming Solution on the Gastric Mucosal $Co_{2}$ Partial Pressure and Serum IL-8 Level during Cardiopulmonary Bypass in Korean Mongrel Dogs)

  • 박건;이종호;김진호;진웅;권종범;김치경;왕영필
    • Journal of Chest Surgery
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    • 제38권12호
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    • pp.807-814
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    • 2005
  • 배경: 체외순환은 심정지를 필요로 하는 모든 심장 수술에서 정지된 심장의 기능을 대신하여 환자의 말초 장기의 혈액순환을 유지하기 위한 필수적인 과정이다. 그러나 체외순환은 필연적으로 인공도관을 관류하는 특성상 신체의 혈관계를 흐르는 혈류와 달리 혈액손상에 따른 전신성 염증반응을 피할 수 없으며, 이러한 전신성 염증반응과 함께 말초혈관의 미세혈관 순환장애가 체외순환동안에 원발장기의 손상을 초래하는 것으로 생각된다. 저자들은 전신성 염증반응을 일으키는 주된 혈액성분인 백혈구를 제거한 충진액을 사용하여 전신성 염증반응을 줄일 수 있는가를 확인하고, 체외순환도중 위점막의 산도를 측정함으로써 위점막의 미세혈류에 대한 백혈구 제거 충진액의 효과를 확인하기 위하여 실험을 진행하였다. 대상 및 방법: 실험군은 15마리의 한국산 잡견을 충진액의 성분에 따라 비혈액성 충진액군, 백혈구 제거 혈액성 충진액군, 백혈구 비제거 혈액성 충진액군으로 각각 5마리씩 세 군으로 나누었다. 세 군 모두에서 2시간의 체외순환 및 연속된 4시간의 마취유지를 시행하였으며, 체외순환 전과 체외순환 후 1시간, 2시간, 체외순환 종료 후 2시간 4시간에 위점막 이산화탄소 농도와 산도, 동맥혈 이산화탄소 분압 과 호기말 이산화탄소 분압을 측정하고, 염증반응의 지표검사를 위하여 동맥혈을 채혈하였다. 전신성 염증반응의 정도는 채취한 동맥혈에서 ELISA (enzyme linked immunosorbent assay)법을 이용하여 IL-8의 수준을 검사하였다. 결과: 1, 위점막의 이산화탄소 농도는 백혈구 제거 혈액성 충진액군이 백혈구 비제거 혈액성 충진액군과 비혈액성 충진액군에 비하여 유의하게 낮았다(p=0.02, 0.01). 2. 위점막의 산도는 백혈구 제거 혈액성 충진액군과 백혈구 비제거 혈액성 충진액군간에 유의한 차이를 보였다(p=0.01). 3. 전신성 염증반응의 정도를 확인하기 위하여 측정한 IL-8의 수준은 백혈구 제거 혈액성 충진액군과 비혈액성 충진액군이 백혈구 비제거 혈액성 충진액군에 비하여 유의하게 낮았다(p=0.01, 0.01). 결론: 백혈구를 제거한 혈액성 충진액을 사용하는 것이 체외순환중 위점막의 미세순환 장애를 방지하고 전신성 염증반응을 감소시킬 수 있음을 확인하였다.

천연혼합냉매를 이용한 압축/흡수식 고온히트펌프의 실험적 연구 (Experimental Study on Compression/Absorption High-Temperature Hybrid Heat Pump with Natural Refrigerant Mixture)

  • 김지영;박성룡;백영진;장기창;나호상;김민성;김용찬
    • 대한기계학회논문집B
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    • 제35권12호
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    • pp.1367-1373
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    • 2011
  • 본 연구에서는 천연냉매를 적용한 압축/흡수식 하이브리드 고온제조 히트펌프를 실험적으로 연구한 결과를 제시하였다. 압축/흡수식 히트펌프는 기존의 증기압축 히트펌프에 비해 고온영역을 포함한 넓은 생산온도범위, 높은 승온기능, 다양한 용량 제어방법 등 여러가지 장점을 가지고 있다. 제작된 하이브리드 히트펌프는 현재 실제 산업현장에 적용하기 이전의 초기 시제품 단계로 실험실에 설치하여 운전하였으며, 주요 구성부품으로는 이단압축기, 흡수기, 재생기, 과열냉각기, 용액 열교환기, 용액펌프, 기액분리기/정류기 등이다. 성능실험에서 $50^{\circ}C$의 열원을 고온 및 저온열원으로 사용한 결과 $90^{\circ}C$ 이상의 고온수 토출과 10 kW급의 난방 용량을 얻을 수 있었다. 혼합냉매의 성분비 변화에 따른 압축기/펌프 유량의 순환비 변화 및 다양한 성능변화를 실험적으로 관찰하였으며, 시스템의 효율과 용량에 있어 최적 성분비가 존재함을 확인하였다.

체외순환 개심술이 혈액응고 요소에 미치는 영향에 관한 임상적 연구 (A clinical study on blood coagulation factors after open heart surgery with extracorporeal circulation)

  • 이철범;박영관
    • Journal of Chest Surgery
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    • 제13권4호
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    • pp.356-363
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    • 1980
  • Even now, the hemorrhagic syndrome after cardiac surgery with the aid or a pump oxygenator constitutes a significant problem. The purpose of this study is to postulate the possible causes of the bleeding after open hear surgery [OHS]. Fifteen consecutive OHS patients with various heart diseases were selected and platelet count, plasma fibrinogen, serum calcium level were observed pre-, intra- and post- operatively until 21 th postoperative day [POD]. The platelet count was significantly decreased with initiation of extracorporeal circulation [ECC] and continued to decrease slowly until cessation of ECC. Within 10 minutes after ECC the platelet count stared to increase. But it was significantly less than preoperative count until 5th POD. The peak count was found on 14th POD and the platelet count was gradually decreased. Plasma fibrinogen also decreased significantly during operation, but it recovered up to preoperative amount within 5 hours after termination of ECC. Thereafter it rapidly increased until 3rd POD when it reached its peak. From 3rd POD it showed slow downward slope until 21st POD, but it remained in significantly higher level than preoperative amount. Serum calcium levels showed minimum fluctuations during the whole course of study. Conclusively, the decrease in platelet count and fibrinogen amount may play a considerable role for the postoperative hemorrhage. But numerous other effects of ECC must be accounted for.

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스탠딩컬럼웰형(SCW) 지중열교환기의 열성능 측정에 관한 실험적 연구 (An Experimental Study on the Thermal Performance Measurement of Standing Column Well type Borehole Heat Exchanger)

  • 이상훈;최용석;안근묵
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2010년도 추계학술대회 초록집
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    • pp.122.2-122.2
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    • 2010
  • Knowledge of ground thermal properties is most important for the proper design of BHE(borehole heat exchanger) systems. The configure type, pipe size and thermal performance of the BHE is highly dependent on the ground source heatpump system-efficiency and instruction cost. Thermal response tests with mobile measurement devices were developed primarily for in-situ determination of design data for Standing Column Well apply. The main purpose has been to determine in-situ values of effective ground thermal conductivity and thermal resistance, including the effect of ground-water flow and natural convection in the boreholes. The test rig is set up on a some trailer, and contains a sub-circulation pump, a boiler, temperature sensors, flow meter and a data logger for recording the temperature and circulation fluid flow data. A constant heating power is injected into the SCW through the test rig and the resulting temperature change in the SCW is recorded. The recorded temperature data are analysed with a line-source model, which gives the effective in-situ values of rock thermal conductivity and thermal resistance of SCW.

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정유압 기계식 변속기의 조향시 동력 순환 특성 (Power Circulation Characteristics of Hydro-Mechanical transmission System in Steering)

  • 김진석;김원;정용호;정순배;김현수
    • 한국자동차공학회논문집
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    • 제5권2호
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    • pp.13-22
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    • 1997
  • Power flow characteristics of a hydro-mechanical transmission system(HMT) are investigated for tracked vehicle in steering. A HMT consisting of two hydrostatic pump motors(HST), several planetary gear trains and steer differential gear is considered. In order to obtain the direction and magnitude of the power flow of the HMT, network theory for the general power transmission is used. Network model for the HMT in steering is developed, which consists of shafts, nodes and transmission elements such as clutch, gear, etc. Power flow analysis procedure consists of two stages : (1) traction force analysis in steering, (2) power flow analysis in HMT. Torque and speed of every transmission element of the HMT is determined from the network analysis. Also, efficiency, mechanical and hydraulic power loss including HST, are obtained. In addition, the regenerative power flow resulting from steering can be studied in graphic display. The power flow analysis program(PCSTEER) developed in this work can be used as a useful design tool for the tracked vehicle with HMT.

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UO$_2$(NO$_3$)$_2$ 용액으로부터 Ammonium Uranyl Carbonate 제조 (A Precipitation of Ammonium Uranyl Carbonate from Uranylnitrate Solution)

  • 김응호;김형수;이규암;유재형;최청송
    • 한국세라믹학회지
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    • 제35권6호
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    • pp.559-568
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    • 1998
  • Studies of preparation condition and characteristics of AUC(ammonium uranyl carbonate) were carried out to optimize AUC process with different reactor sizes and precipitation methos. As results four types of precipitates with different chemical compositions and morphologies were obtained from the reaction of {{{{ {(NH }_{4 }) { }_{2 } {CO }_{3 } }} with {{{{ {UO }_{2 }( {NO }_{3 }) { }_{2 } }} solution. A phase diagram has been made and crystal structure and chemical composition of each phase have been characterized by using SEM X-ray IR and thermal analysis. It was found that ammonium uranyl carbonate {{{{ {(NH }_{4 }) { }_{4 } {UO }_{2 } {(CO }_{3 }) { }_{3 } }} with monoclinic crystal morphology could be syn-thesized when the mole ratio of in {{{{ {(NH }_{4 }) { }_{2 } {CO }_{3 }/ {UO }_{2 } {(NO }_{3 }) { }_{2 } }} in the solution was higher than 5 Also a mechanism and a precipitating condition on rounding of the AUC particle were examined in the course of the AUC pre-cipitation. The rounding of the AUC particle was possible only by external circulation using pump not by internal circulation using agitator.

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Effect of Korea Red Ginseng on the Symptoms and Hemodynamics in Healthy Elders

  • Jin En-Yuan;Li Ya-Jun;Yang Lian-Xing;Jin Ming;Wei Yu-Lin;Nam Ki Yeul
    • 고려인삼학회:학술대회논문집
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    • 고려인삼학회 2002년도 학술대회지
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    • pp.27-34
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    • 2002
  • Clinical study on hemodynamics of healthy elders before and after tread mill. Using doubleblind, placebo-controlled study design. Seventy-five 50-70 years old volunteers without organic disease were divided into two groups, Ginseng group and control group. Each subject was received 3 g Korea Red Ginseng (KRG) capsules or placebo per day for 4 weeks. Before and after administration 4 weeks, the symptoms were asked and hemodynamics parameter such as pump function, systolic function, preload and afterload were recorded before and after tread mill 1,5, 10 minutes by the method of thoracic impedance cardiograph. The result showed that Ginseng could improve quality of life, had obvious effect of increasing PEP (pre-ejection period), PEP/LVET (pre-ejection period/left ventricular ejection period), PCWP (wedged pressure pulmonary capillary). The change rate of HR (heart rate), SV (stroke volume) in KRG group were much lowered, while EF (ejection fraction), LVET (left ventricular ejection period), LVEDP (left ventricular end diastolic pressure) was recovered much quickly. The circulation showed Ginseng could improve the quality of life though its promoting circulation function which are increasing both the systolic function and the preload.

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초전도케이블시스템 유지.보수에 따른 신뢰성 평가 시험 (Reliability Assesment Test on the Regular Maintenance of HTS Cable System)

  • 손송호;양형석;임지현;최하옥;김동락;류희석;황시돌
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2009년도 하계학술대회 논문집
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    • pp.361-361
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    • 2009
  • KEPCO High Temperature Superconducting (HTS) cable system rated with $3\Phi$, 22.9kV, 1250A was laid in 2006, and the long term test is in progress. The HTS cable system with the cooling system has been operated below cryogenic temperature. That environment exposes the system to the thermo-mechanical stress due to the significant temperature difference, and the cooling system has moving parts for the forced circulation of the coolant. Therefore the HTS cable system experiences thermal fatigue and moving part such as liquid nitrogen pump need a regular replacement every 5000 hours Building the assessment criterion, the maintenance procedure was established and regular preventive maintenance was done; improvement of the termination structure and the replacement of the bearing of liquid nitrogen pump. Following the proper process, the reliability assessment test including He leakage detection and the stability of flow rate was performed. This paper describes the process and result of the first regular maintenance of KEPCO HTS cable system

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공압식 심실보조장치의 개발 및 평가 (Development and Evaluation of Pneumatic Ventricular Assist Device)

  • 이상훈;박이태;김삼현;한동선;이학중
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1995년도 춘계학술대회
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    • pp.247-250
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    • 1995
  • The purpose of this paper is to develop diaphragm-type pneumatic ventricular assist device(VAD) for clinical application and to evaluate its performance through the mock circulation system. The blood housing and diaphragm are made by coating pellethane on the metallic mold and the back plate is made by machining process. The relations of cardiac output(CO) vs. beat rate and CO vs. systolic-to-diastolic rate was estimated through the mock test and hemodynamic waves are recorded for the evaluation of VAD. As a result, the volume of blood pump is 70 ml, maximum CO is 5 L/min and CO has a close relation to the input resistance of blood pump. The hemodynamic data and waves showed this system can be applicable to the animal experiment.

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TLIM 전자펌프를 이용한 전도성 용융금속의 유동특성 해석 (The Analysis of Flow Characteristics of Conductive Liquid Metal Using TLIM Electromagnetic Pump)

  • 김창업;전문호;권정태;임효재
    • 조명전기설비학회논문지
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    • 제22권12호
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    • pp.130-141
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    • 2008
  • 본 논문에서는 원통형 선형유도전동기를 이용한 순환식 유동시스템에서의 유체특성을 해석하였다. 먼저 유동시스템에 필요한 추력 40[N] 원통형 선형유도전동기를 등가회로법과 유전알고리즘을 이용하여 설계하였다. 이 힘이 유체시스템에 작용하는 경우 유체의 특성은 유체방정식과 전자기 방정식을 결합하여 해석하여야 한다. 본 논문에서는 유체의 속도에 따라 층류해석과 난류해석이 가능한 해석프로그램을 개발하고, 각각에 대한 유충특성 해석을 하였다. 또한 전자기력에 의한 추력이 시스템에 추가되었을 때의 특성을 분석하였다.