• 제목/요약/키워드: Cinnoline

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A Green One-Pot Protocol for Regioselective Synthesis of New Substituted 7,8-Dihydrocinnoline-5(6H)-ones

  • Khalafy, Jabbar;Rimaz, Mehdi;Ezzati, Mahnaz;Prager, Rolf H.
    • Bulletin of the Korean Chemical Society
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    • 제33권9호
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    • pp.2890-2896
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    • 2012
  • A simple regioselective synthesis of cinnoline derivatives was achieved by a one-pot three component synthetic methodology. New substituted 7,8-dihydrocinnolin-5(6H)-ones are prepared via one-pot three component reaction of arylglyoxals with 1,3-cyclohexanedione and dimedone in the presence of hydrazine hydrate in moderate to good yields.