• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.30 no.3
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• pp.201-210
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• 2017

Objectives : To report the patient suspected chronic arsenic intoxication after Korean medicine treatment. Methods : One patient with highly suspected chronic arsenic intoxication was selected. He was suspected to be chronic arsenic intoxication because symptoms and hair heavy metals test. Acupuncture was applied for twice a day and herbal medicine(Pyeonghyeol-eum) was administered in 28 days. Evaluation method applied to xeroderma, pruritus, psoriasis were overall dry skin score(ODS), visual analogue scale(VAS), pruritus grading system(PGS). Results : Pyeonghyeol-eum, acupuncture and the other Korean medicine treatments improved xeroderma, pruritis, psoriasis after 28 days of treatment. ODS decreased from 3 to 2. VAS of Pruritus decreased from 8 to 1. PGS decreased from 15 to 4. Adverse effects were not reported. Conclusions : This study shows that the Korean medicine treatment was effective in impoving symptoms of chronic arsenic intoxication. But the additional study will be conducted for revealing dermatitis caused by chronic arsenic intoxication.

• CELLMED
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• v.4 no.3
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• pp.20.1-20.7
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• 2014

Ethanolic leaf extract of Bauhinia variegata has been tested for its possible antioxidant potentials against sodium arsenite induced toxicity in mice. Mice were randomized into two groups of five and fifty mice. Group I consisting of 5 mice without any treatment with food and water ad libitum which served as normal control. Group II mice were fed with sodium arsenite in drinking water at 100 ppm concentration for two monthsthen they were segregated into five groups which were treated differently. Group II a mice received only arsenic as sodium arsenite with drinking water, Group II b were fed chronically 1 : 20 alcohol to distilled water (vehicle), Group II c, d, e mice were orally fed 50 mg/kg, 150 mg/kg and 250 mg/kg of B. variegata leaf extract of once daily for 15 and 30 days respectively along with arsenic. Several toxicity marker enzymes such as gamma glutamyl transferase, lactate dehydrogenase, aspartate and alanine aminotransferase, acid and alkaline phosphatase, catalase and superoxide dismutase along with haematological variables such as glucose 6-phosphate dehydrogenase, creatinine, bilirubin, haemoglobin and sugar in different groups of treated and control mice were studied. Results obtained from the in vivo experiment revealed that administration of sodium arsenite caused a significant increase in some enzymes while decrease in some. A similar trend was also observed with haematological variables. In contrast B. variegata treatment at 150 mg/kg favourably modulated these alterations and maintained the antioxidant status than other two doses i.e. 50 mg/kg and 250 mg/kg thereby making it a good candidate to be used as supportive palliating measures in arsenic induced toxicity.