• Title/Summary/Keyword: Chromosome 4

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Anesthetic considerations for a pediatric patient with Wolf-Hirschhorn syndrome: a case report

  • Tsukamoto, Masanori;Yamanaka, Hitoshi;Yokoyama, Takeshi
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.17 no.3
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    • pp.231-233
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    • 2017
  • Wolf-Hirschhorn syndrome is a rare hereditary disease that results from a 4p chromosome deletion. Patients with this syndrome are characterized by craniofacial dysgenesis, seizures, growth delay, intellectual disability, and congenital heart disease. Although several cases have been reported, very little information is available on anesthetic management for patients with Wolf-Hirschhorn syndrome. We encountered a case requiring anesthetic management for a 2-year-old girl with Wolf-Hirschhorn syndrome. The selection of an appropriately sized tracheal tube and maintaining intraoperatively stable hemodynamics might be critical problems for anesthetic management. In patients with short stature, the tracheal tube size may differ from what may be predicted based on age. The appropriate size ( internal diameter ) of tracheal tubes for children has been investigated. Congenital heart disease is frequently associated with Wolf-Hirschhorn syndrome. Depending on the degree and type of heart disease, careful monitoring of hemodynamics is important.

Karyotypes of Three Ascidians (Chordata; Ascidiacea) from Korea

  • Choe, Byung-Lae;Qi, Hongying;Rho, Boon-Jo
    • Animal cells and systems
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    • v.4 no.2
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    • pp.105-107
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    • 2000
  • Cytogenetic features of three ascidian species were studied with specimens obtained from Korean coastal areas. The gonadal tissue was processed in order to obtain mitotic and meiotic chromosomes. The chromosome numbers of Amaroucium pliciferum turned out to be 2n=26 and n=l3 with 2sm, 3st, 8t and Halocynthia roretzi to be 2n=16 and n=8 with 6m, 2t. Diploid number of chromosomes in Dendrodoa aggregata was 64 with 32t. The karyotypes of these Korean ascidians were reported for the first time.

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Breeding of Tetraploid in Codonopsis lanceolata (Sieb. et Zucc.) Trautvetter by Colchicine Treatment

  • Kim, Ik-Hwan;Kim, Hag-Hyun;Hong, Eui-Yon;Yun, Jong-Sun;Yun, Tae;Hwang, Ju-Kwang;Lee, Cheol-Hee
    • Plant Resources
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    • v.6 no.3
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    • pp.227-232
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    • 2003
  • Present studies were carried out to produce tetraploid plants by colchicine treatment using seeds, seedlings and shoot tips of Codonopsis lanceolata. Three tetraploid plants of C. lanceolata were produced from seeds which absorbed 0.1 % colchicine solution for 12 hours, and 0.5% colchicine solution for 1 and 6 hours from seedlings, respectively. But tetraploid was not produced from shoot tips treated by colchicine solution. Compared to diploid, tetraploid plants had larger stomata, but less number of stomata. Fresh weight of tetraploid plants was 1.4∼3.6 times heavier than diploid plants.

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A Phylogenetic Analysis for Hox Linked Gene Families of Vertebrates

  • Kim, Sun-Woo;Jung, Gi-La;Lee, Jae-Hyoun;Park, Ha-Young;Kim, Chang-Bae
    • Animal cells and systems
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    • v.12 no.4
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    • pp.261-267
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    • 2008
  • The human chromosomes 2, 7, 12 and 17 show genomic homology around Hox gene clusters, is taken as evidence that these paralogous gene families might have arisen from a ancestral chromosomal segment through genome duplication events. We have examined protein data from vertebrate and invertebrate genomes to analyze the phylogenetic history of multi-gene families with three or more of their representatives linked to human Hox clusters. Topology comparison based upon statistical significance and information of chromosome location for these genes examined have revealed many of linked genes coduplicated with Hox gene clusters. Most linked genes to Hox clusters share the same evolutionary history and are duplicated in concert with each other. We conclude that gene families linked to Hox clusters may be suggestion of ancient genome duplications.

Cytogenetic and Histological Characteristics of Ginseng Hairy Root Transformed by Agrobacterium rhizogenes (Agrobacterium rhizogenes에 의하여 형질전환된 인삼 모상근의 세포 유전학적 및 조직학적 특성)

  • 고경민
    • Journal of Plant Biology
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    • v.36 no.1
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    • pp.75-81
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    • 1993
  • Ginseng (Panax ginseng C.A. Meyer) hairy root transformed with Agrobacterium rhizogenes (strain A4) was examined cytogenetically and histologically to assess its characteristics. The optimum growth of hairy root obtained in hormone-free MS medium (sucrose 30 g/L, pH5-6) for long period cultures. All hairy root strains (HB1, HB2, HB3) had the 2n diploid number (2n=48) of chromosomes in root tip cells. There were no alteration in chromosome structure except in one cell of HB3 strain. Results of SDS-PAGE showed a few difference in pattern and number of bands between normal and hairy root of ginseng. The root anatomy of normal root and hairy root differed each other. The hairy root had a clearly defined vascular strand, and the morphology of cortical cells were disorganised with large intercellular spaces.

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Taxonomic Strudy of the Combitid Fish, Cobitis Iutheri Rendahl and C. striata Ikeda (Cobitidae) from Korea (한국산 점줄종개(Cobitis lutheri) 와 줄종개(C.striata)의 분류학적 연구)

  • 김익수;이금영
    • Animal Systematics, Evolution and Diversity
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    • v.4 no.2
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    • pp.91-102
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    • 1988
  • Both Cobitis lutheri Rendahl and C.striata Ikeda previously regarded as the subspecies of C.taenia are revised here and raised to the species rank based on the distinct color pattern on their body sides in relation to the shpae of lamina circularis and suborbital spine, and distinct distributional patter. C. lutheri was similar to C. striata in chromosome number and karyotype, but chromosomal polymorphism as Robert sonian event was confirmed only in the population of C.lutheri studies. Both, C. kutheri and C..striata have disjunct ranges : the former in western Korea and east-northern China Mainland, the latter in the Smjin River of korea and west-southern Japan. hybridization between C. lutheri and C. striata by secondary contact appeared in the limited zone of the Dongjin River, Chllabuk-do province, korea, but the evidence for habitat segregation between them suggests the possibility that natural hybridization occurs between the two species and introgression results. We consider that the two species were produced as ecological equivalent species in the different branch stream of the Paleo-Hwangho River , The time of recession of sea level during the gracial period.

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Inheritance of Golden Coloration in the Zebrafish, Danio rerio (Zebrafish (Danio rerio)의 체색 변이에 관한 유전 분석)

  • 송춘복;이병문
    • Journal of Aquaculture
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    • v.10 no.4
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    • pp.395-402
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    • 1997
  • The study has been conducted in order to understand the inheritance of body color in the wild type zebrafish (zebra danio), Danio rerio, and its golden mutant (golden danio). The body color was also studied to determine the effect of golden coloration on the survival rate of zebrafish eggs and larvae up to 15 days after fertilization. Reciprocal monohybrid crosses between the wild and the golden type of zebrafish indicated that golden coloration was controlled by a single gene which had two alleles. Transmission of these alleles from parents to their progenies followed the principles of dominance and segregation based on Mendelian inheritance. Similar results from the reciprocal crosses implied that a locus for golden coloration was located on an autosomal chromosome. On the other hand, average survival rates from four different types of mating between, and within, zebra and golden danio suggested that golden coloration seemed to be associated with the survival rate of zebrafish, especially in its early embryonic stage. This indicated that homozygous recessive golden mutation was likely to weaken the golden danio's chance of survival.

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Taxonomic Investigation of Erythroglossum minimum Okamura and Sorella repens (Okamura) Hollenberg (Delesseriaceae, Rhodophyta)

  • Kim, Gwang Hoon
    • Journal of Plant Biology
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    • v.37 no.4
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    • pp.403-410
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    • 1994
  • The taxonomic criterion between Erythroglossum and Sorella was reappraised based on Korean plants of E. minimum Okamura and S. repens (Okamura) Hollenberg. Development of the reproductive organs was observed from field collected plants as well as cultured plants. The Polyneura-tuype procarp which comprised one group of sterile cells and two carpogonial branches arising from a supporting cell was observed in both species. Distribution of tetrasporangial sori was irregular in both species, so it is not relevant to distinguish Sorella from Erythroglossum by the characteristic of tetrasporangial distribution. E. minimum and S. repens were very similar in vegetative form, but were reproductively isolated. Chromosome numbers were given as n=ca. 30 in S. repens and n=ca. 41 in E. minimum, respectively.

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Performance Control of the Capacitated Re-entrant Line using Genetic Approach (유전자 알고리즘을 이용한 유한용량 재진입 라인 성능 제어)

  • Choi, Jin-Young
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.31 no.4
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    • pp.106-113
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    • 2008
  • 본 논문에서는 유한용량 재진입 생산라인에서의 스케줄링 문제에 대한 유전자적 접근 방법을 제안하였다. 알고리즘에서 사용되는 염색체의 구조는 워크스테이션의 버퍼레벨에 대한 모든 가능한 경우를 고려하여 정의되었으며, 염색체의 각 유전자에는 그에 대응되는 시스템 상태에서 우선 순위를 갖는 작업 단계의 값이 할당되도록 하였다. 또한, 제안된 알고리즘의 구현 방법으로서 워크스테이션의 버퍼와 프로세싱 자원을 할당할 때 작업 간 우선 순위를 고려하는 동시에 각 워크스테이션의 로컬 유휴 상태를 지양하는 우선순위 기반 랜덤화 정책 알고리즘을 제안하였다. 실험을 통하여 제안된 알고리즘의 성능을 평가하였으며, 기존에 무한용량 재진입 생산라인 스케줄링 문제에 많이 이용되었던 휴리스틱과 비교하여 보다 효율적임을 보였다.