• 제목/요약/키워드: Chromosome 1

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On the Chromosome Distribution of Uterine Carcinoma in Culture (배양한 자궁암세포의 염색체 구성에 관하여)

  • Kang, Yung-Sun;Kim, Suk-Whan;Park, Eun-Ho
    • The Korean Journal of Zoology
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    • v.15 no.1
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    • pp.15-21
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    • 1972
  • The chromosome constitutions in two cases of uterine carcinoma were studied in vitro with particular interest to the non-random distribution. The results obtained are as follows: 1. The chromosome numbers of one case were found within a normal diploid range with mode at 46, while those of the other were whithin hypotriploid range with mode at 60. 2. The data from the latter case indicated possible existence of non-random distribution of chromosome.

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Applications of Geostatistics to the Quantitative Analysis of Genetic Instability in Carcinogenesis

  • Kim Hyoung-Moon
    • Communications for Statistical Applications and Methods
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    • v.13 no.1
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    • pp.167-175
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    • 2006
  • It has long been recognized that cancer is a genetic disease. To find this measures of genetic instability, stain cells with chromosome specific probes using chromosome in-situ hybridization technique is adopted. Even though in-situ hybridization technique is powerful, truncation of nuclei often results in under-representation of chromosome copies in slides due to the sectioning of tissue blocks. Because of this problem we suggest three different methods to analyze the cervical cancer data set. We observe that genetic instability is an increasing function of histology and our suggested model is the best in detecting genetic instability of tumorigenesis processes.

Study on the chromosome number of the Korean native mulberry (한국 재래상의 염색체 연구)

  • 김윤식
    • Journal of Sericultural and Entomological Science
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    • v.3
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    • pp.59-60
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    • 1963
  • It was prved by the author that : 1. The Smear Method with the buds of mulberry just before sprouting, can be used as one of the best methods in observation of the chromosome number. 2. The chromosome number of the Korean native mulberry is 28 in all (2n=28). 3. Triploid in mulberry can never occur under natural weather condition.

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Studies on Meiosis of PMC's in P. alba × glandulosa and Their Parents (P. alba × glandulosa와 그 양친(両親)의 Pollen Mother Cell의 Meiosis에 관(關)한 연구(硏究))

  • Cheung, Hyon Pae;Chon, Sang Kun;Kim, Mal Sook;Kim, Chung Suk
    • Journal of Korean Society of Forest Science
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    • v.45 no.1
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    • pp.51-61
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    • 1979
  • The chromosome behavior and it's synapsis in the meiosis of pollen mother cell were studied on Populus alba L. as a female parent tree, Populus glandulosa Uyeki as a male parent tree and their hybrid, Populus alba x glandulosa. 1. At metaphase I, the number of nuclear plates with early separation chromosome were observed with the lowest proportion of 11.0% in Populus glandulosa and with the highest proportion of 13.0% in Populus alba${\times}$glandulosa. 2. At metaphase II, early separation chromosomes appeared with the frequency of 11.0% in Populus alba${\times}$glandulosa. But the frequency was not different with those of the parental trees. 3. At anaphase I, lagging chromosomes appeared with some high rate of 11.6% in Populus alba${\times}$glandulosa and yet the number of chromosome bridges in populus alba x glandulosa almost were not different with the partental trees. 4. At anaphase II, lagging chromosomes appeared with some high frequency of 10.2% in Populus alba${\times}$glandulosa and the chromosome bridges in Populus glandulosa appeared with the highest frequency in all studied trees. 5. The frequency of abnormal pollen sporad was the highest value of 8.2% in Populus alba${\times}$glandulosa among the studied trees. With the results, it might be assured that the chromosome segregation and it's synapsis behaved normally in Populus alba, Populus glandulosa and Populus alba x glandulosa, and so all the studied trees could produced normal pollens.

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A systematic study of Abeliophyllum distichum (Oleaceae) based on cytological characters (세포학적 형질에 기초한 미선나무의 계통분류학적 연구)

  • Tae, Kyoung-Hwan;Tho, Jae-Hwa;Kim, Joo-Hwan
    • Korean Journal of Plant Taxonomy
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    • v.35 no.2
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    • pp.143-151
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    • 2005
  • Cytological characteristics of Abeliophyllum distichum (Oleaceae), endemic to Korea, was examined. Somatic chromosome numbers was 2n = 28 which corresponds to diploid based on x=14. Chromosome length was varied continuously from $1.00{\mu}m$ to $2.03{\mu}m$. Karyotype of Abeliophyllum distichum was investigated in this study for the first time. The cytological characteristics including basic chromosome number, continuous variation of chromosome length, diploid and karyotype were similar to those of the genus Forsythia, which indicated the close relationship between Abeliophyllum and Forsythia, and consequently the two genera seemed to be included to same tribe.

The Genetic Algorithm using Variable Chromosome with Chromosome Attachment for decision making model (의사결정 모델을 위한 염색체 비분리를 적용한 가변 염색체 유전 알고리즘)

  • Park, Kang-Moon;Shin, Suk-Hoon;Chi, Sung-Do
    • Journal of the Korea Society for Simulation
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    • v.26 no.4
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    • pp.1-9
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    • 2017
  • The Genetic Algorithm(GA) is a global search algorithm based on biological genetics. It is widely used in various fields such as industrial applications, artificial neural networks, web applications and defense industry. However, conventional Genetic Algorithm has difficulty maintaining feasibility in complicated situations due to its fixed number of chromosomes. This study proposes the Genetic Algorithm using variable chromosome with chromosome attachment. And in order to verify the implication of changing number of chromosomes in the simulation, it applies the Genetic Algorithm using variable chromosome with chromosome attachment to antisubmarine High Value Unit(HVU) escort mission simulation. As a result, the Genetic Algorithm using variable chromosome has produced complex strategies faster than the conventional method, indicating the increase of the number of chromosome during the process.

Karyotype of Lilium Miqueliannum Makino (하늘말나리의 핵형)

  • 손진호
    • Journal of Plant Biology
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    • v.14 no.4
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    • pp.14-18
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    • 1971
  • Lilium Miquelianum Makino is a species which originated in Korea. The Karyotype of the species was examined in materials collected at Mts. Kaya, Kasan, Chejung, and Kaji. The results are as follows: 1) The somatic chromosome number was found to be 2n=24. 2) The karyotype is described as: K=2Am+2Bkm+2Csst+2Dsst+2Ests+2Fst+2Gst+2Hst+2Ist+2Jsst+2Kst+2Lst m: metacentric, sm: submetacentric st: subtelocentric, s: secondary constriction 3) A single subcentric supernumerary B-chromosome was found in some bulbs from Mt. Kasan. 4) The shape of the supernumerary B-chromosome was similar to that of the E chromosome which had separated at its secondary constriction and lost its lower chromosome fragment. 5) From three to eight nucleio of varying sizes were found in the telophase or interphase nucleus of root tip cells. The maximum number of eight nucleoli corresponds to the number of chromosomes that have a secondary constriction.

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Simultaneous Overexpression of Integrated Genes by Copy Number Amplification of a Mini-Yeast Artificial Chromosome

  • Jung, Heo-Myung;Kim, Yeon-Hee
    • Journal of Microbiology and Biotechnology
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    • v.28 no.5
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    • pp.821-825
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    • 2018
  • A copy number amplification system for yeast artificial chromosomes (YACs) was combined with simultaneous overexpression of genes integrated into a YAC. The chromosome VII (1,105 kb) was successfully split to 887 kb, 44 kb containing the element for copy number amplification, and a 184-kb split-YAC. The 44-kb split-mini YAC was amplified a maximum of 9-fold, and the activity of the reporter enzymes integrated into the split-mini YAC increased about 5-7-fold. These results demonstrate that the mini-YAC containing a targeted chromosome region can be readily amplified, and the specific genes in the mini-YAC could be overexpressed by increasing the copy number.

No Association of the Human Y Chromosome with Blood Pressure in Korean Male Population

  • Kang, Byung-Yong;Kim, Seon-Jeong;Lee, Kang-Oh
    • Toxicological Research
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    • v.19 no.1
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    • pp.29-31
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    • 2003
  • It has been reported that the genetic variations in the Y chromosome has influence the blood pressure in some Caucasian male populations, but the effect in non-Caucasian population is unclear. In the present study, we examined the relationship between blood pressure and a HindIII RFLP of Y chromosome in 152 unrelated male individuals of ethnically homogeneous Korean origin. There were no significant differences in systolic and diastolic blood pressures between genotype groups, respectively. However, the frequency of A genotype in Korean population was much higher than those of Caucasian populations (P<0.05). Therefore, the results of this study will con-tribute the better understanding the genetic characteristics of Y chromosome in Korean population.

Effects of gamma-irradiation on the infectivity and chromosome aberration of Clonorchis sinensis

  • Park, Gab-Man;Yong, Tai-Soon
    • Parasites, Hosts and Diseases
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    • v.41 no.1
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    • pp.41-45
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    • 2003
  • Effects of gamma irradiation on the worm survival and chromosomal aberration of Clonorchis sinensis were studied. The metacercariae irradiated with various amounts of gamma radiation (ranging from 5 Gy to 50 Gy) were fed to rats, and the effects were compared with those of non-irradiated controls. Recovery rates of adult worms in irradiated groups were reduced gradually as increasing of the irradiation doses. No worm was recovered from rats which were fed with 50 Gy irradiated metacercariae. The chromosome number was 2n = 56 in all worms from all experimental groups. However, the groups irradiated with 20 Gy, 25 Gy or 30 Gy showed variations in the chromosome number, depending on different cells in the same individual. Radiation doses used in this study did not appear to induce chromosome aberrations, however, irradiation with 30 Gy showed slightly reduced chromosome size.