• Title/Summary/Keyword: Choi Wee

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Two cases of Patients with Nonspecific Symptoms Diagnosed as Ischemic Heart Disease (비특이적인 증상을 나타내는 허혈성(虛血性) 심질환(心疾患) 진단 2례)

  • Baik, Jong-Woo;Jung, Ki-Yong;Hsia, Yu-Chun;Park, Jong-Hyeong;Jeon, Chan-Yong;Choi, You-Kyung
    • The Journal of Internal Korean Medicine
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    • v.29 no.4
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    • pp.1130-1137
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    • 2008
  • Objectives : Oriental medical doctors usually use the three-finger pulse diagnosis method to observe disease. Since it is difficult to diagnose ischemic heart disease (IHD) objectively by this diagnostic method, we performed the study to diagnose it as soon as possible by using Yuk Bu Jung Wee Jin Mac(六部定位診脈) and electrocardiogram(ECG). Methods : Patients who had abdominal discomfort were observed by Yuk Bu Jung Wee Jin Mac(六部定位診脈) and we presumed they had heart disease and checked them with electrocardiogram(ECG). Results : We diagnosed it early by using Yuk Bu Jung Wee Jin Mac(六部定位診脈) and electrocardiogram (ECG). Conclusions : The study suggests that it is easy to diagnose IHD early using Yuk Bu Jung Wee Jin Mac(六部定位診脈) and ECG. More data related to IHD is needed.

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Actin Dysfunction Induces Cell Cycle Delay at G2/M with Sustained ERK and RSK Activation in IMR-90 Normal Human Fibroblasts

  • Shrestha, Deepmala;Choi, Daeun;Song, Kiwon
    • Molecules and Cells
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    • v.41 no.5
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    • pp.436-443
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    • 2018
  • The actin cytoskeleton plays a key role in the entry of mitosis as well as in cytokinesis. In a previous study, we showed that actin disruption delays mitotic entry at G2/M by sustained activation of extracellular signal-related kinase 1/2 (ERK1/2) in primary cells but not in transformed cancer cell lines. Here, we examined the mechanism of cell cycle delay at G2/M by actin dysfunction in IMR-90 normal human fibroblasts. We observed that de-polymerization of actin with cytochalasin D (CD) constitutively activated ribosomal S6 kinase (RSK) and induced inhibitory phosphorylation of Cdc2 (Tyr 15) in IMR-90 cells. In the presence of an actin defect in IMR-90 cells, activating phosphorylation of Wee1 kinase (Ser 642) and inhibitory phosphorylation of Cdc25C (Ser 216) was also maintained. However, when kinase-dead RSK (DN-RSK) was overexpressed, we observed sustained activation of ERK1/2, but no delay in the G2/M transition, demonstrating that RSK functions downstream of ERK in cell cycle delay by actin dysfunction. In DN-RSK overexpressing IMR-90 cells treated with CD, phosphorylation of Cdc25C (Ser 216) was blocked and phosphorylation of Cdc2 (Tyr 15) was decreased, but the phosphorylation of Wee1 (Ser 642) was maintained, demonstrating that RSK directly controls phosphorylation of Cdc25C (Ser 216), but not the activity of Wee1. These results strongly suggest that actin dysfunction in primary cells activates ERK1/2 to inhibit Cdc2, delaying the cell cycle at G2/M by activating downstream RSK, which phosphorylates and blocks Cdc25C, and by directly activating Wee1.

Accumulation of Butyltin Compounds in Shellfish and Fish from Korean Coastal Areas

  • Choi, Hee-Gu;Kim, Sang-Soo;Moon, Hyo-Bang;Lee, Pil-Yong;Gu, Bon-Kyu
    • Journal of the korean society of oceanography
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    • v.37 no.2
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    • pp.82-89
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    • 2002
  • Butyltins (BTs) were measured in 2 species of shellfish and 16 species of fish collected along the Korean coast. Tributyltin (TBT) was detected in the mussels and oysters of sentinel organisms (20 to 940 ng Sn/g dry wt), indicating widespread contamination of TBT in the Korean coast. The elevated concentrations of TBT in the shellfish found in the sites near harbors or shipyards suggested that antifouling paints are probable major sources of butyltins in these areas. The TBT compound was detected in 12 out of 16 fish samples. The concentrations of TBT in fish muscles wee between 7 and 151 ng Sn/g dry wt, while the level in whole body of anchovy was very high (793 ng Sn/g dry wt). Exposure doses to Korean people via consumption of these marine products wee evaluated. The results suggested that the environmental levels of TBT were below the level of concern.

Anomaly Detection Using Subgraph Pattern Analysis in Graph Streams (스트림 그래프에서 서브 그래프 패턴 분석을 이용한 이상 패턴 감지)

  • Wee, ji-woon;Choi, do-jin;Lim, jong-tae;Bok, kyoung-soo;Yoo, jae-soo
    • Proceedings of the Korea Contents Association Conference
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    • 2019.05a
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    • pp.287-288
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    • 2019
  • 그래프에서 이상 패턴은 정상 그래프와 상이하게 다른 양상을 갖는 그래프를 의미한다. 이상 패턴을 판단하기 위해서는 정상데이터 정확한 정의가 요구된다. 본 논문에서는 스트림 그래프에서 실시간으로 이상 패턴을 감지하는 기법을 제안한다. 제안하는 기법은 정상 서브그래프의 패턴(정상 패턴)을 정의하고 정점 간 연결 관계를 고려한다.

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A Direction of Developing a Traditional Cultural Content of Korean Court Dance Oyangseon - With a Base on the Historical Transmission, Reception of Asian Traditional Dance - (궁중정재 <오양선>의 전통문화콘텐츠화 시론 - 아시아 전통춤의 전파와 변용을 바탕으로 -)

  • Huh, Dong-sung
    • (The) Research of the performance art and culture
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    • no.35
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    • pp.509-541
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    • 2017
  • The basic intent of this thesis lies in proposing a meaningful direction of developing cultural content by combining Asian traditional dance forms which hold cultural closeness in common historically. For this study, this paper selected Oyangseon(五羊仙; 'Five Taoist Hermits on Five Sheep'), a Korean court dance of Chinese origin as an example as the Oyangseon story is commonly found in ancient Vietnam and China as well as Korea. Its original narrative is a mythic story that five hermits had come down to ancient Vietnam region riding on five sheep of five colors to bestow 6 ears of milets to people. Later, the story was spread to other regions to be reformed into Woljeongjeon(越井傳; Vietnam), Choi Wee(崔?; China) and Oyangseon(Korea) that have different plot and background. While Woljeongjeon and Choi Wee were adapted into novels that describe the hero Choi Wee's mysterious adventure to be repaid his father's previous devotion to ancient King's shrine. Meanwhile, the epic narrative of Korean Oyangseon proves the modification of the original myth by adding a Seowangmo(西王母; a Chinese mythic heavenly queen) motif while it was enacted as a court dance to praise king's long life and pray country's prosperity following Confucian concept. Based on this historical lineage of Oyangseon story, I searched for the possiblity of constructing a cultural content program by combining the Oyangseon dance of three countries. While there was Oyangseonmu(五羊仙舞) in China which was recently composed by referring to Korean Oyangseon, any traditional dance item based on Oyangseon story was not available in Vietnam. Thus, I tried to propose the Vietnam Dance College to choreograph a new dance item with Woljeongjeon story while using the traditional dance technique, music, costume, etc. of Vietnam as most as possible. As a result, I could display a direction of developing a cultural content by staging three countries' dance items based on Oyangseon story at Korean National Haneul Theater in Oct 2016.