• Journal of the Korean Society of Food Science and Nutrition
• /
• v.27 no.4
• /
• pp.625-632
• /
• 1998

To enhance the antimutagenic and anticancer activities of chinese cabbage kimchi, 13 kinds of kimchi, which were different kinds and levels of sub-ingredient added kimchi, were prepared and fermented at 15℃ for 1 day and then at 5℃ up to pH 4.3. The antimutagenic effects of the methanol extracts of the kimchi were studied by using Ames mutagenicity test in Salmonella typhimurium TA100 and SOS chromotest in E. coli PQ37. Among the kimchi samples, high ratio of red pepper powder(7%) and garlic(2.8% or 5.2%) added kimchi, 1% chinese pepper powder added kimchi and organic cultivated chinese cabbage kimchi significantly reduced(p<0.05) the mutagenicity induced by aflatoxin B1(AFB1) in Ames test and SOS response against N-methyl-N'-nitro-N-nitrosoguanidine(MNNG) in SOS chromotest, and also the kimchi inhibited more effectively(p<0.05) the survival and growth of AGS human gastric adenocarcinoma cells than the standarized kimchi on the SRB assay, MTT assay and growth inhibition test. These results suggest that the antimutagenic and anticancer activites of kimchi can be increased by the sub-ingredients such as organic cultivated chinese cabbage, red pepper powder, garlic and chinese pepper powder.

• Korean Journal of Agricultural Science
• /
• v.43 no.3
• /
• pp.459-467
• /
• 2016

In Korea, the market size for environment-friendly agricultural products has reached a plateau, even though many Korean consumers still show a high level of preference for environment-friendly agricultural products. In order to solve this problem, some Korean farmers and marketers are starting to try to export their products to many countries, including China. China, in particular, is becoming one of the fastest rising market for Korean environment-friendly agricultural products, after the signing of the Free Trade Agreement with China. However, little research has been done or reported about the purchase behaviors of Chinese consumers. The purpose of this paper is to analyze the environment-friendly agricultural product purchase behavior (especially, mandarin orange and muskmelon) of consumers in the Chinese market and to present some useful implications for Korean farmers and marketers. Through survey in China (especially, Beijing and Shanghai) and frequency analysis, this study made the following findings: first, Chinese consumers show a very strong concern for environment-friendly agricultural products. Second, many Chinese consumers usually buy environment-friendly agricultural products more than two times per month. Third, Chinese consumers give more value to freshness and food-safety than taste when they make decisions on buying environment-friendly mandarin orange and muskmelon. These can have some implications for the exportation of environment-friendly agricultural products.

• BMB Reports
• /
• v.44 no.6
• /
• pp.381-386
• /
• 2011

In the present study, we characterized the function of HS1-binding protein 3 (HS1BP3), which is mutated in essential tremor and may be involved in lymphocyte activation. We found that HS1BP3 localized to the mitochondria and endoplasmic reticulum partially. Overexpression of HS1BP3 induced apoptosis in HEK293T and HeLa cell lines. When these cell lines were transfected with HS1BP3, they exhibited nuclear DNA condensation, externalization of phosphatidylserine (PS), and cleavage of poly ADP ribose polymerase (PARP). Furthermore, suppression of HS1BP3 or HS1 expression attenuates HS1BP3 induced apoptosis. In addition, HS1BP3 enhanced activator protein 1 (AP-1)-mediated transcription in a dose-dependent manner. Therefore, we conclude that HS1BP3 regulates apoptosis via HS1 and stimulates AP-1-mediated transcription.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.16 no.6
• /
• pp.1833-1848
• /
• 2022

Named entity recognition (NER) is an important basic task in the field of Natural Language Processing (NLP). Recently deep learning approaches by extracting word segmentation or character features have been proved to be effective for Chinese Named Entity Recognition (CNER). However, since this method of extracting features only focuses on extracting some of the features, it lacks textual information mining from multiple perspectives and dimensions, resulting in the model not being able to fully capture semantic features. To tackle this problem, we propose a novel Multi-view Semantic Feature Fusion Model (MSFM). The proposed model mainly consists of two core components, that is, Multi-view Semantic Feature Fusion Embedding Module (MFEM) and Multi-head Self-Attention Mechanism Module (MSAM). Specifically, the MFEM extracts character features, word boundary features, radical features, and pinyin features of Chinese characters. The acquired font shape, font sound, and font meaning features are fused to enhance the semantic information of Chinese characters with different granularities. Moreover, the MSAM is used to capture the dependencies between characters in a multi-dimensional subspace to better understand the semantic features of the context. Extensive experimental results on four benchmark datasets show that our method improves the overall performance of the CNER model.

• Korean Journal of Agricultural Science
• /
• v.41 no.4
• /
• pp.303-308
• /
• 2014

This study was conducted in order to utilize the basic data for weed control by surveying the occurrence of weed species. Total 63 sites of upland Chinese cabbage fields in Chungnam Provinces were investigated. The result of survey, 71 weed species in 25 families were identified and classified to 39 annuals, 16 biennials and 16 perennials. Based on the occurrence ratio, the most weed species belonged to Compositae (20 species). 8, 6 and 5 weed species belonged to Poaceae, Cruciferae and Polygonaceae, respectively, and these 10 weed species in the most six families accounted for 50% of total weed occurrence. The most dominant weed species in upland Chinese cabbage fields were Portulaca oleracea (8.07%), followed by Digitaria ciliaris (7.54%), Rorippa palustris (6.44%), Chenopodium album (5.73%), Echinochloa crus-galli (5.02%) and Cyperus amuricus (3.95).

• BMB Reports
• /
• v.41 no.4
• /
• pp.287-293
• /
• 2008

In a yeast two-hybrid screen, we identified the microtubule-destabilizing protein SCG10 as a potential effector protein of $BRI_3$. The association was verified using GST pull-down, Co-IP, and their perinuclear co-localization. The analysis of in vitro microtubule polymerization/depolymerization showed that the binding of $BRI_3$ to SCG10 effectively blocked the ability of SCG10 to induce microtubule disassembly, as determined by turbidimetric assays. In intact PC12 cells, $BRI_3$ exhibited the ability to stabilize the microtubule network and attenuate the microtubule-destabilizing activity of SCG10. Furthermore, co-expression of $BRI_3$ with SCG10 attenuated SCG10-mediated PC12 cell neurite outgrowth induced by NGF. These results identify a novel connection between a neuron-specific BRI protein and the cytoskeletal network, suggesting possible roles of BRI3 in the process of neuronal differentiation.

• Asian Journal of Business Environment
• /
• v.8 no.3
• /
• pp.33-41
• /
• 2018

Purpose - This study focused on the attitude differences towards harmony-focused Ad and uniqueness-focused Ad, also those towards brand advertised in each of the two type Ads between self-construals. Research design, data, and methodology - Main survey was conducted online with the people in China, and collected 107 data through harmony Ad questionnaire and 109 data through uniqueness Ad questionnaire. Anova and t-test were used to verify hypotheses. Results - First, More positive attitude towards harmony-focused Ad and the brand in it there was at interdependent Chinese consumers than at independent Chinese consumers. Second, the independent Chinese consumers and the interdependent Chinese consumers did not form significant attitude difference towards uniqueness-focused Ad. However the independent Chinese consumers showed more positive attitude towards the brand in the uniqueness-focused Ad than the interdependent Chinese consumers. Conclusions - By highlighting the attributes of Chinese consumers' self-construal, to appeal to interdependent Chinese consumers, marketers should develop harmony-focused advertisement, and they should appeal to independent Chinese consumers by using uniqueness-focused advertisement. However the harmony might be pursued as the main content in the overall environment by Chinese people. Therefore it is necessary for the marketers to consider the harmony even when appealing them by emphasizing the uniqueness.

• Asian-Australasian Journal of Animal Sciences
• /
• v.33 no.4
• /
• pp.531-538
• /
• 2020

Objective: Evidence from previous reports indicates that pig domestication in East Asia mainly occurred in the Mekong region and the middle and downstream regions of the Yangtze River. Further research identified two new origin centers for domestic pigs in the Tibetan Plateau and the islands of Southeast Asia. However, due to the small sample size of Tibetan pigs, details of the origin and spread of Tibetan pigs has not yet been established. Methods: We analyzed mitochondrial DNA control region (D-loop) variation in 1,201 individuals from nine Tibetan pig populations across five provinces. Comprehensive Tibetan pig samples were taken to perform the most detailed analysis of Tibetan pigs to date. Results: The result indicate that Rkaze pigs had the lowest level of diversity, while Changdu pigs had the highest diversity. Interestingly, these two populations were both in the Tibetan Plateau area. If we calculate diversity in terms of each province, the Tibetan Plateau area had the lowest diversity, while the Chinese province of Gansu had the highest diversity. Diversity gradient analysis of major haplotypes suggested three domestication centers of Tibetan pigs in the Tibetan Plateau and the Chinese provinces of Gansu and Yunnan. Conclusion: We found two new domestication centers for Tibetan pigs. One is in the Chinese province of Gansu, which lies in the upstream region of the Yellow River, and the other is in the Chinese province of Yunnan.

• BMB Reports
• /
• v.42 no.9
• /
• pp.599-604
• /
• 2009

Selenium possesses the chemotherapeutic feature by inducing apoptosis in cancer cell with trivial side effects on normal cells. However, the mechanism in which is not clearly understood. Emerging evidence indicates the overlaps between the autophagy and the apoptosis. In this study, we have investigated the role of autophagy in selenium-induced apoptosis in NB4 cells. We find that autophagy is suppressed in NB4 cells treated by sodium selenite, as measured by electron microscope, acridine orange staining and western blot. Moreover, selenite combined with autophagy inhibitor contributes to the up-regulation of apoptosis, while the PI3K/Akt signaling pathway is down- regulated. Consistently, when the inhibitor of PI3K was applied, the autophagic level significantly decreased. In summary, sodium selenite increases NB4 cell apoptosis by autophagy inhibition through PI3K/Akt, and the inhibition of autophagy contributes to the up-regulation of apoptosis.

• Asian-Australasian Journal of Animal Sciences
• /
• v.19 no.9
• /
• pp.1229-1233
• /
• 2006

To find the candidate genes concerned with ovulation rate of sheep, Differential Display Reverse Transcription Polymerase Chain Reaction was employed to find the differently expressed cDNA controlling ovulation in the Small Tail Han sheep of polyembryony and in Tan sheep of single birth. Twenty-four primer pairs of three anchored primers and eight arbitrary primers were assembled to amplify the specialized bands from these sheep. Positive cross tests were applied to optimize the ascertainable PCR conditions in which different special bands can be identified by silver strain in one PCR tube. After eliminating the false positive PCR products by Northern hybridization, 24 differential display bands were acquired from the ovary in the Small Tail Han sheep. These EST bands were sequenced and 18 different ESTs were found in which five ESTs had several copies and 13 ESTs had only one copy. Comparing these ESTs with homologous sequences by BLAST in the GenBank, there were six ESTs with known open reading frame (ORF) and function, three ESTs with known ORF and no function, and 9 ESTs without homologous sequence. These ESTs partly represent several genes such as NOS2, tensin, TCRA, CDKN1A, ESR1 and ACTB which express especially in Small Tail Han sheep.