• 생약학회지
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• 제38권1호
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• pp.45-49
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• 2007

Chinese crude drug "Lu-ti-cao"(鹿蹄草) has been used as a remedy for beriberi, cut bleeding, snake bite, etc. In Korea, the drug is called "Nok Je Cho" and has been used as a folk medicine of the same effect as that of Chinese equivalent. The original plant of this drug has not yet been as certained. To clarify the botanical origin of "Nok Je Cho", the morphological and anatomical characteristics of the leaves of Pyrola species growing in Korea, i.e. P. incarnata, P. japonica, P. minor, P. renifolia, P. secunda were studied. As a result, it was clarified that "Nok Je Cho" was the leaf of Pyrola japonica and Pyrola minor.

• 생약학회지
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• 제25권2호
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• pp.188-193
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• 1994

'Hoo Bak' is one of the Chinese crude drugs used mainly to cure a headache, apoplexy and dyspepsia. With regard to the botanical origin of 'Hoo Bak', it has been considered to be Machilus thunbergii of Lauraceae in Korea. But there has no pharmacognostical confirmation on it. To clarify the botanical origin of 'Hoo Bak', the anatomical characteristics of the bark of Machilus thunbergii, Magnolia officinalis and Magnolia obovata were studied. As a result, it was clarified that 'Hoo Bak' from Korea was the bark of Machilus thunbergii of Lauraceae.

• 생약학회지
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• 제33권3호통권130호
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• pp.157-168
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• 2002

Aconites distribute widely in northern hemispere of the earth reaching to arctic zone from warm and temperate one. Chinese crude drug 'Cho O'(草烏) has been used as a remedy for apoplexy, dyspepsia, neuralgia, chronic rheumatis etc. Though the botanical origin of the crude drug has been considered to be Aconitum species of Ranunculaceae, there has been no confirmation on it. To clarify the botanical origin of Cho O, the morphological and anatomical characteristics of the roots of Aconitum species growing in Korea, i.e. A. chiisanense, A. ciliare, A. jaluense, A. napiforme, A. proliferum, A. pseudoproliferum and A. triphyllum were studied. As the result, Cho O was proved to be the roots of Aconitum triphyllum, A. jaluense, A. chiisanense and A. napiforme.

• 생약학회지
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• 제26권4호
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• pp.411-418
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• 1995

In order to clarify the originality of several Alisma Rhizomes, we investigated the differences of their morphological, anatomical and physiochemical characteristics. Morphological observation shows the variability of Alisma shape and quality. The diversities in morphological shapes and qualities of tuber were observed among different origins. Chinese product looked like corm shape, but korean's irregular shape. The microscopic observation of korean Alisma revealed the presence of irregular vascular bundle which was scattered transversely and longitudinaly, which was different from that of the rhizome. This facts suggest that the portion of crude drug in Alisma should be the corm rather than the rhizome. In the physicochemical differences, chinese Alisma contains larger amount of mineral elements such as K, Na and Ca than korean Alisma. On the contrary, protein contents in lyophilized powder of aqueous extracts in korean Alisma rhizome was significantly higher than chinese Alisma rhizome. The leaves and stems contained larger amount of Ca and Na than tuber, and may be used as the osmotic diuretics for chinese traditional medicine.

• 대한약침학회지
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• 제21권3호
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• pp.203-206
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• 2018

Objectives: There is an increasing number of complex diseases that are progressively more difficult to be controlled using the conventional "single compound, single target" approach as demonstrated in our current modern drug development. TCM might be the new cornerstone of treatment alternative when the current treatment option is no longer as effective or that we have exhausted it as an option. Orthogonal stimulus-response compatibility group study is one of the most frequently employed formulas to produce optimal herbal combination for treatment of multi-syndromic diseases. This approach could solve the relatively low efficacy single drug therapy usage and chronic adverse effects caused by long terms administration of drugs that has been reported in the field of pharmacology and medicine Methods: The present review was based on the Science Direct database search for those related to the TCM and the development of antihypertensive TCM herbal combination using orthogonal stimulus-response compatibility group studies approach. Results: Recent studies have demonstrated that the orthogonal stimulus-response compatibility group study approach was most frequently used to formulate TCM herbal combination based on the TCM principles upon the selection of herbs, and the resulting formulated TCM formula exhibited desired outcomes in treating one of global concerned complex multi-syndromic diseases, the hypertension. These promising therapeutic effects were claimed to have been attributed by the holistic signaling mechanism pathways employed by the crude combination of herbs. Conclusion: The present review could serve as a guide and prove the feasibility of TCM principles to be used for future pharmacological drug research development.

• 생약학회지
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• 제38권4호
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• pp.305-307
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• 2007

Chinese crude drug 'Kang Whal' has been used mainly as a headache in common cold, rheumatic arthralgia and aching of the back and shoulder. To clarify the botanical origin of Kang Whal from Korea, the anatomical characteristics of Ostericum koreanum Maxim. and Notopterygium incisium Ting ex H.T.Chang were studied. As a result, it was clarified that Kang Whal from Korea was the underground part of Ostericum koreanum.

• 생약학회지
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• 제39권2호
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• pp.135-136
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• 2008

Chinese crude drug 'Gye Ji(桂枝)' is listed in Shen-nung-pen-tsao-ching(神農本草經), as the remedy for dispelling pathogenic factor from the exterior of the body by diaphoresis. In Korean, herbals origin of Gye Ji is branch of Cinnamomum cassia. Considering the descriptions in many herbals(本草書), the origin of Gye Ji reported by Su-Ching(蘇敬), Han-Pao-Sheng(韓保昇) and Li -Shin-Chen(李時珍) is regarded as the bark of branch of Cinnamomum cassia.

• 생약학회지
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• 제31권2호
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• pp.209-215
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• 2000

'Ha Go Cho (夏枯草)' is one of the Chinese crude drugs used mainly as a diuretic. With regard to the botanical origin of 'Ha Go Cho', it was reported by Su et al. that those from China were originated from the fruited spica of Prunella vulgaris L. of Labiatae. It was, however, for the herba or spica of Prunella vulgaris L. var. lilacina Nakai from Korea. According to survey of markets in Korea, most of the materials collected in the markets seemed to be originated from Prunella plant, while some seemed to be Thesium plant of Santalaceae. To clarify the botanical origin of 'Ha Go Cho', the anatomical characteristics of Prunella vulgaris L. var. lilacina Nakai and Thesium chinense Turcz. were studied. As a result, it was clarified that some 'Ha Go Cho' from Korea were the herba or spica of Prunella vulgaris var. lilacina, whereas some others were the herba of Thesium chinense.

• 생약학회지
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• 제31권1호
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• pp.63-71
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• 2000

'Si Ho'(柴胡) is one of the chinese crude drugs used mainly to cure inflammation, fever, cough, hepatitis, jaundice, etc. Though the botanical origin of the crude drug has been considered to be Bupleurum species of Umbelliferae, there has been no pharmacognostical study. To clarify the botanical origin of 'Si Ho', the morphological and anatomical characteristics of the roots of Bupleurum species growing in Korea, such as Bupleurum euphorbioides Nakai, Bupleurum falcatum L., Bupleurum leveillei Bois., Bupleurum longiradiatum Turcz. and Bupleurum scorzoneraefolium Wild. were studied. As a result, it is authentified that 'Si Ho' was proved to be the root of Bupleurum falcatum and B. scorzoneraefolium and 'Jug Si Ho' was the root of B. longiradiatum.

• 생약학회지
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• 제42권1호
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• pp.6-8
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• 2011

'BaegDuOng(白頭翁)' is one of the Chinese crude drugs used mainly as a pruritus, arthritis, cough and abdominal pain. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of 'BaegDuOng', the morphological and anatomical characteristics of Pulsatilla species growing in Korea, i.e. Pulsatilla koreana Nakai and P. cernua (Thunb.) Spreng. were studied. As a result, BaegDuOng from Korea was proved to be the root of Pulsatilla koreana.