• Journal of Ginseng Research
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• v.40 no.3
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• pp.245-250
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• 2016

Background: Ginsenosides are the major effective ingredients responsible for the pharmacological effects of ginseng. Malonyl ginsenosides are natural ginsenosides that contain a malonyl group attached to a glucose unit of the corresponding neutral ginsenosides. Methods: Medium-pressure liquid chromatography and semipreparative high-performance liquid chromatography were used to isolate purified compounds and their structures determined by extensive one-dimensional- and two-dimensional nuclear magnetic resonance (NMR) experiments. Results: A new saponin, namely malonyl-ginsenoside Re, was isolated from the fresh flower buds of Panax ginseng, along with malonyl-ginsenosides Rb1, Rb2, Rc, Rd. Some assignments for previously published $^1H$- and $^{13}C$-NMR spectra were found to be inaccurate. Conclusion: This study reports the complete NMR assignment of malonyl-ginsenoside Re, $Rb_1$, $Rb_2$, Rc, and Rd for the first time.

• Journal of Microbiology and Biotechnology
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• v.26 no.12
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• pp.2214-2223
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• 2016

Toll-like receptors (TLRs) can recognize conserved molecular patterns and initiate a wide range of innate and adaptive immune responses against invading infectious agents. The aim of this study was to assess the transcript profile of mink TLRs (mTLRs) in mink peripheral blood mononuclear cells (PBMCs) and a range of tissues, and to explore the potential role of mTLRs in the antiviral immune response process. The results indicated that the mTLR partial nucleotide sequences had a high degree of nucleotide identity with ferret sequences (95-98%). Phylogenetic analysis showed that mammalian TLRs grouped into five TLR families, with a closer relationship of the mTLRs with those of ferret than the other mammalian sequences. Moreover, all the mTLRs were ubiquitously expressed in lymphoid organs (spleen and lymph nodes) and PBMCs. Interestingly, the mTLR expression patterns in lung, uterus, and heart showed quite a lot of similarity. Another remarkable observation was the wide expression of mTLR1-3 mRNAs in all tissues. Among the analyzed tissues, skeletal muscle was revealed to being the lowest repertoire of mTLR expression. Additionally, mink PBMCs exposed to the canine distemper virus revealed significant upregulation of mTLR2, mTLR4, mTLR7, and mTLR8 mRNAs, indicating that mTLRs have a role in innate immunity in the mink. Collectively, our results are the first to establish the basic expression patterns of mTLRs and the relationship between mTLRs and a virus, which will contribute to better understanding of the evolution and the functions of mTLRs in the innate immune system in minks.

• Journal of Ginseng Research
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• v.42 no.1
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• pp.27-34
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• 2018

Background: The use of different methods for the processing of ginseng can result in alterations in its medicinal properties and efficacy. White ginseng (WG), frozen ginseng (FG), and red ginseng (RG) are produced using different methods. WG, FG, and RG possess different pharmacological properties. Methods: WG, FG, and RG extracts and pure ginsenosides were administered to rats to study the pharmacokinetics and tissue distribution characteristics of the following ginsenosides-DRg1, Re, Rb1, and Rd. The concentrations of the ginsenosides in the plasma and tissues were determined using UPLC-MS/MS. Results: The rate and extent of absorption of Rg1, Re, Rb1, and Rd appeared to be affected by the different methods used in processing the ginseng samples. The areas under the plasma drug concentration-time curves (AUCs) of Rg1, Re, Rb1, and Rd were significantly higher than those of the pure ginsenosides. In addition, the AUCs of Rg1, Re, Rb1, and Rd were different for WG, FG, and RG. The amounts of Rg1, Re, Rd, and Rb1 were significantly (p < 0.05) higher in the tissues than those of the pure ginsenosides. The amounts of Re, Rb1, and Rd from the RG extract were significantly higher than those from the WG and FG extracts in the heart, lungs, and kidneys of the rats. Conclusion: Our results show that the use of different methods to process ginseng might affect the pharmacokinetics and oral bioavailability of ginseng as well as the tissue concentrations of Rg1, Re, Rd, and Rb1.

• The Journal of Industrial Distribution & Business
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• v.8 no.3
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• pp.11-18
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• 2017

Purpose - This study aims to analyze the effects of the social support on the economic activities from the Korean Chinese residing in Korea. Particularly, this paper focuses on the consequence of the economic activity intention according to the three kinds of social support. Research design, data, and methodology - For the statistics process of data collected by this survey, SPSS 19 statistics package program was used through data-coding and data-cleaning processes to analyze the data in this study. Results - This hypothesis was selected partially. As a result of investigating hypotheses in detail, Hypothesis 1-2 was significant as shown in the significance level 0.1, and when the emotional support was regarded important, the will of economic activities was also higher. Hypothesis 1-2 was found to be meaningful with the significance level of 0.05, and when the social support was regarded important, the will of economic activities was also higher. Lastly, Hypothesis 1-3 was found to not be statistically significant. Conclusions - The results of this study are expected to be used as basic data for vitalization of the Korean Chinese' economic activities and governmental support for it, and to be a guideline in preparing successful strategies for expansion of the Korean Chinese' economic activities in the future by applying these results.

• Mycobiology
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• v.47 no.4
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• pp.391-400
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• 2019

A survey of mushrooms was conducted in Xishuangbanna, Yunnan Province, China, in the rainy season (May to October) of 2012, 2013, and 2014, during which 16 specimens of Termitomyces were collected. Preliminary macro- and micro-characteristics, together with ITS sequence data, showed that four of the specimens belonged to a new species (Termitomyces fragilis), while the other 12 belonged to T. aurantiacus, T. eurrhizus, T. globules, T. microcarpus, and T. bulborhizus. In this paper, T. fragilis is introduced as a species new to science based on morphological characterization and phylogenetic analyses. Macro- and micro- morphological descriptions, color photographs and line drawings of the new species, and a phylogenetic tree to show the placement of the new species are provided. T. fragilis is then compared with other closely related taxa in the genus Termitomyces.

• Journal of Korean Society of Rural Planning
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• v.23 no.3
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• pp.53-60
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• 2017

In order to export Korean spray roses to the China, it is needed to analyse chinese preferences, rose attributes, and purchase intentions. The purpose of this study is to present the implications on the production and distribution of roses for export by analyzing the quality preference attributes and purchase intention of Korean rose for Chinese flower experts. A survey on the preference and purchase intention of Korean flower roses by Chinese flower experts was conducted through face - to - face interviews with flower show participants in China. Approximately 100 Chinese flower experts who participated in the Flower Show in 2016 received the questionnaire, and 86 survey results could be used for analysis. Survey data were analyzed using ordered probit and bivariate probit models. As a result of an analysis, it was found that Chinese flower experts were more likely to buy Korean roses than Chinese roses even if they consider flower color, leaf shape and size and color diversity. The probability of purchasing more than twice the price was higher than that of the color diversity considering the flower shape, leaf shape and size, but the bivariate order probit model was larger than that of flowers, leaves and size, and the order of probability size was changed. In order to increase the export of Korean spray roses to the Chinese market, We need to increase Chinese experts' preferences and satisfaction. For this purpose, it is very important to develop export varieties of roses with large flower buds and shape / coloring, and to apply the useful post-harvest technology that can extend freshness and distribution period of export roses.

• International Commerce and Information Review
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• v.12 no.3
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• pp.197-221
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• 2010

China has experienced repid economic growth since it opened its economic market. Apparently, China tends to follow the worldwide trends and it plans to play a leading role in the world. As China has become a global manufacturing center as well as a manufacturing powerhouse with its high economic growth rate, China's logistics industry has entered a stage of fast growth and the demand of logistics infrastructure and third party logistics service are increasing rapidly. This study is to present some efficient entering strategies of Korean logistics firms in China by examining the current situations of logistics industry in China and some business strategies of international logistics firms in China. From the research which sees consequently investigated a various policy, a system and a law about chinese logistics industry and present condition of the Chinese goods enterprise and instance analysis of the large Chinese corporation that branch out to undeveloped markets led and a Chinese logistics industry and problem point escape hereafter the heightening of competitiveness plan which is rational under presenting boil.

• Journal of Distribution Science
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• v.11 no.9
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• pp.31-34
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• 2013

Purpose - This paper aims to explain that the Chinese distribution market will continue to bring tremendous business opportunities to commercial enterprises, given the relatively strong economic fundamentals and substantial government-led measures to boost domestic demand. Research design, data, methodology - A survey was conducted on China's retail market data during 2012. By empirically analyzing the data for retail sales of online markets and franchises, we conclude that the online retail market in China will continue to grow. Results - Based on data from 2012, 2013 is expected to be a challenging year for the retail sector, as both external and internal pressure is likely to persist. This paper outlines some major challenges facing retailers in China. Conclusions - The study shows that retailers in the Chinese market will face some major challenges: 1) the Chinese retail market is considerably affected by an uncertain economic outlook 2) an unfair environment of competition exists and 3) product safety is a serious issue. However, in the future, China's retail market will continue to bring tremendous business opportunities to commercial enterprises, given the relatively strong economic fundamentals and substantial government-led measures to boost domestic demand.

• 중국학논총
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• no.71
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• pp.237-254
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• 2021

It can be said that the fishery industry in ancient China did not originally occupy a very special economic area even when it was started. At that time, the fishery industry was only treated as a means for the livelihood of ordinary people. Over time, the value and economic benefit of aquatic products began to be valued. Its origin can be said to have originated from Yugong(禹貢), which was established by King Yu. These records made it clear that the ancient kings placed great importance on the economic value of seafood and the importance of the fishery industry in the government. Thus, the fishery industry was established as a part of the socio-economic system. In ancient China, the fishery industry was one of the industrial systems that supported traditional Chinese society along with agriculture. It will be possible to analyze the way of thinking of modern Chinese people on the fishery industry through the study of the fishery industry in the traditional era of China. And based on this analysis, I think that it will be able to contribute to a certain extent in establishing a theoretical foundation for countermeasures against the reckless overfishing of fishery resources by Chinese fishermen in the West Sea, which is currently a problem.

• Journal of Ginseng Research
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• v.41 no.2
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• pp.209-214
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• 2017

Background: Both ginsenoside Re and B-complex vitamins are widely used as nutritional supplements. They are often taken together so as to fully utilize their antifatigue and refreshing effects, respectively. Whether actually a drug-nutrient interaction exists between ginsenoside Re and B-complex vitamins is still unknown. The objective of this study was to simultaneously investigate the effect of B-complex vitamins on the antifatigue activity and bioavailability of ginsenoside Re after their oral administration. The study results will provide valuable theoretical guidance for the combined utilization of ginseng and B-complex vitamins. Methods: Ginsenoside Re with or without B-complex vitamins was orally administered to mice to evaluate its antifatigue effects and to rats to evaluate its bioavailability. The antifatigue activity was evaluated by the weight-loaded swimming test and biochemical parameters, including hepatic glycogen, plasma urea nitrogen, and blood lactic acid. The concentration of ginsenoside Re in plasma was determined by liquid chromatography-tandem mass spectrometry. Results: No antifatigue effect of ginsenoside Re was noted when ginsenoside Re in combination with B-complex vitamins was orally administered to mice. B-complex vitamins caused to a reduction in the bioavailability of ginsenoside Re with the area under the concentration-time curve from zero to infinity markedly decreasing from $11,830.85{\pm}2,366.47h{\cdot}ng/mL$ to $890.55{\pm}372.94h{\cdot}ng/mL$. Conclusion: The results suggested that there were pharmacokinetic and pharmacodynamic drug-nutrient interactions between ginsenoside Re and B-complex vitamins. B-complex vitamins can significantly weaken the antifatigue effect and decrease the bioavailability of ginsenoside Re when simultaneously administered orally.