• 디지털융복합연구
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• 제11권10호
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• pp.123-131
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• 2013

본 연구의 목표는 초등부 자폐성장애 아동들의 적응행동 향상을 위해 적응행동기술을 지원하기 위한 스마트 콘텐츠의 개발 방향을 제시하는 것이다. 특수학교 교사 및 장애학생 교육기관 전문가들의 AHP설문을 통해 스마트 콘텐츠의 개발의 필요성 및 효과에 대한 적응행동기술의 중요도를 도출하였다. 또한 어떠한 적응행동기술 분야가 스마트 콘텐츠로 개발하기에 적합한지 앱개발 전문가들의 토론과 설문을 통해 그 중요도를 도출하였다. 분석결과 스마트 콘텐츠로 개발에 적합하고 그 효과가 높은 적응행동 기술은 언어이해, 시간이행 및 엄수, 이동기술, 옷입기, 개인위생이었다. 본 연구를 토대로 교육당국은 단편적인 교육용 스마트 콘텐츠 개발보다는 효과적이고 활용도가 높은 자폐성장애 아동들의 특성 및 특수교사나 부모의 요구에 맞는 스마트 콘텐츠 개발 및 지원체계를 구축하고자 노력해야 한다.

• Clinical Psychopharmacology and Neuroscience
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• 제16권4호
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• pp.415-421
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• 2018

Objective: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairment in social skills and communication with repetitive behaviors. Etiology is still unclear although it is thought to develop with interaction of genes and environmental factors. Oxytocin has extensive effects on intrauterine brain development. Vitamin D, affects neural development and differentiation and contributes to the regulation of around 900 genes including oxytocin receptor gene. In the present study, the contribution of D vitamin receptor and oxytocin receptor gene polymorphisms in the development of ASD in Turkish community was investigated. To our knowledge, this is the first study examining these two associated genes together in the literature. Methods: Eighty-five patients diagnosed with ASD according to DSM-5 who were referred to outpatient clinics of Child and Adolescent Psychiatry of Başkent University and Mersin University and 52 healthy, age and gender-matched controls were included in the present study. Vitamin D receptor gene rs731236 (Taq1), rs2228570 (Fok1), rs1544410 (Bsm1), rs7975232 (Apa1) polymorphisms and oxytocin receptor gene rs1042778 and rs2268493 polymorphisms were investigated using real time polymerase chain reaction method. Results: No significant difference between groups in terms of distribution of genotype and alleles in each of polymorphisms for these genes could be found. Conclusion: Knowledge of genes and polymorphisms associated with the development of ASD may be beneficial for early diagnosis and future treatment. Further studies with larger populations are required to demonstrate molecular pathways which may play part in the development of ASD in Turkey.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제18권2호
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• pp.117-122
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• 2007

Practice parameters for non-pharmacological treatment of children and adolescents with pervasive developmental disorders are based on the scientific literature for evidence-based practices. Appropriate educational and behavioral interventions are important in improving the long-term outcome in pervasive developmental disorders. Early and sustained intervention appears to be particularly important. The goal for interventions is to gain pragmatic skills for verbal communication, playing with peers, daily living routines, self-management, and social adaptation. Appropriate involvement and collaboration with parents and family are essential for well-functioning intervention programs. The life-long nature of autism implies that the clinician should maintain an active role in long-term treatment planning and family support. Vocational training and training for more independent living are important for adolescents with autism. Professionals should be knowledgeable about local and national resources and opportunities for family support as well as support of the individual.

• 대한한방소아과학회지
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• 제24권3호
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• pp.81-91
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• 2010

Objectives: The basic cause of developmental disability is congenital weakness, which is a disorder of the kidney according to the Oriental medicine definition. I suggest the oriental medicine music therapy, which can improve congenital weakness and recover the kidney dysfunction. Methods: This study focused autism and Asperger syndrome in terms of Oriental medicine, and also considered view points from the Western medicine. Conclusions 1. The kidney monitors vital elements which were produced from the bone marrow. Therefore, the growth and the development of a skeletal structure are related to the strength and weakness of kidney, which is measured in Qi score. 2. In a case of the deficiency of kidney, an essence due to congenital defect, it shows the symptoms of the developmental disability such as sluggish reaction and physical movements, falling of memory, hearing, and eyesight. 3. For the kidney disorder, "Eum music therapy", one of the oriental medicine music therapies, can promote development of the kidney and kidney-Qi score for the children with developmental disability.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제22권4호
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• pp.287-293
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• 2011

Objectives : The region of chromosome 5p14 is known to be associated with autism spectrum disorder (ASD). The cadherin9 (CDH9) and cadherin10 (CDH10) genes are located in the region of chromosome 5p14 and reported to be associated with ASD in the Caucasian population. We performed an association study to identify if single nucleotide polymorphisms (SNPs) located on the CDH9 and CDH10 genes are associated in the Korean population. Methods : Genomic DNA was extracted from the blood of 214 patients with ASD and 258 controls. SNPs selected from two genes were genotyped using an Illumina Golden-Gate Genotyping assay with VeraCode technology. Statistical analysis was performed using SAS and Plink software. Results : All controls and ASD patients were in Hardy-Weinberg equilibrium. In the results of logistic regression analyses for the genotype model and the chi-square test for the allele model, we found that SNPs on the CDH9 and CDH10 genes were not associated with ASD. Conclusion : Our data suggests that the CDH9 and CDH10 genes are not associated with ASD in the Korean population.

• 한국정보전자통신기술학회논문지
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• 제8권6호
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• pp.478-482
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• 2015

치료적 효과에 대한 선행연구의 분석 결과로 게임놀이치료가 ADHD, 틱장애, 의사소통 발달 장애, 자폐성 등과 같은 장애를 가진 아동의 주의집중력, 과잉행동 및 틱증상 감소, 언어적 의사소통 증가, 부적절한 사회적 행동 감소 등과 같은 사회 정서 발달에 효과적인 것으로 보고되었다. 본 연구는 아날로그와 디지털을 병합한 디지로그 방식의 놀이치료 컨텐츠를 개발하고자 한다. 이는 일반인을 비롯하여 치매노인, 지적장애인등의 치료에도 효과적인 방법이라 판단이 된다. 또한 아날로그 놀이와 디지털적 요소들을 융합하여 유아 스마트폰 중독이 초래하는 문제점을 방지하기 위한 디지로그적 관점의 새로운 놀이 시스템을 개발하고자 한다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제4권1호
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• pp.27-38
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• 1993

전반적 발달장애는 가장 심각한 소아정신과 장애중 하나로 발달의 여러가지 영역에 있어 이상 소견을 보인다. 약물치료로 전반적 발달장애를 완치 할 수 없으며 치료효과 역시 비특이적이다. 그러나 일부의 전반적 발달장애 아동에게 약물치료는 매우 중요하기도 하고, 행동치료나 교육에 임하는 데에 있어 휠씬 도움을 줄 수 있다. 지금까지 가장 많이 연구된 항정신병 약물인 halopcridol은 임상적으로나 통계적으로 확실히 위약보다 훌륭한 효과를 보이고 있고, 약물의 부작용을 초래하지 않으면서 변별학습이나 모방적 언어사용등 긍정적인 기능을 촉진하는 것으로 보고되고 있다. 그러나 이러한 halopcridol의 투여는 약물과 관련된 운동장애를 초래할 수 있기 때문에 보다 안전한 다른 약물을 찾고자 하는 이유가 된다. 지금까지의 몇몇 생화학적인 연구들은 전반적 발달장애 아동의 일부에서 대조군에 비하석 혈중내 세로토닌치가 높거나, 내인성 opioid 측정치가 높은 군이 있을 것이라는 보고를 하고 있다. 이러한 소견을 근거로 하여 약물치료가 시도 되기도 하였는데, 예를들면, fenfluramine이나 naltrexone등이 그러하다. 그러나 아직 까지의 결과는 결론적이지 못하다. 이 약물들과 이 밖에도 지금까지 전반적 발달장애 아동에게 사용되어진 약물들과 그들의 효과에 대하여 고찰하고자 한다.

• 한국HCI학회논문지
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• 제9권2호
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• pp.61-68
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• 2014

테이블탑 게임들은 다수가 동시에 인터랙션 할 수 있는 특성을 바탕으로 사용자들 간의 사회성 및 협업 능력을 향상시키기 위한 수단으로 활용되어 왔다. 특히, 아동들에 대한 교육 심리학적 모델 및 행동 특성을 고려하였을 때, 테이블탑 게임은 사회성이 낮은 장애아동들의 협업 능력을 향상시키는 도구로써 쓰일 수 있다. 그러나 기존의 테이블탑 협업 게임들은 유사한 수준의 장애아동들만을 대상으로 하였기 때문에, 통합교육 이론에서 제시하는 인성적 및 인지적인 효과들을 반영하기가 어렵다. 통합교육 환경을 위한 교구로써 테이블탑 게임이 활용될 수 있기 위해서는 비장애아동과 장애아동 모두에게 동등한 몰입도를 보장하고 자발적 상호작용을 가능하게 디자인 요소들이 포함되어야 한다. 따라서, 본 논문에서는 통합교육 방법론에 기반하여 인지적 및 사회적 지수가 다른 아동들을 위한 멀티터치 테이블탑 협업게임을 디자인하고 이를 구현한다. 사용자 평가를 통해 기존 통합교육 환경에서 사용되는 게임 도구와의 몰입 수준 및 상호작용 유형을 비교한다. 실험 결과, 장애아동의 자리이탈 및 이상 행동과 같은 부정적인 상호작용이 감소하였고, 아동들 간의 신체적 및 언어적 의사소통과 같은 긍정적인 상호작용 횟수가 증가하였다. 또한 게임을 수행한 아동들이 장애유무와 관계없이 높은 참여 수준과 공통 집중 시간을 보임으로써, 제안된 게임이 아동들의 몰입도를 향상시켰음을 확인하였다.

• 융복합기술연구소 논문집
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• 제2권2호
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• pp.5-12
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• 2012

Recently, peoples are suffering from various psychological disorders such as addiction, phobia, depression, and bipolar disorder. Moreover, children with ADD/ADHD and autism are increasing. Korean tends to regard the psychological disorders as taboo. Therefore, it is unusual case that the mental patient gets the psychological therapy. Virtual reality has come to the spotlight as a useful tool for the therapy due to its anonymity and easy accessibility. The therapy in the virtual reality is called cyber-therapy. Emotion of the patient is important for the treating process. The objective of this paper is to review the researches on the treatment of psychological disorders using the virtual reality and prospect the affective interaction technology for the cyber-therapy.

• 동의신경정신과학회지
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• 제16권2호
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• pp.25-34
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• 2005

Background and Objectives There was no clinical data except literary study on mutual correlation with autistic disorder in Western medical diagnosis and five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲) in Oriental medical diagnosis. This study was performed to investigate the correlation of five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲) to the children with autistic disorder and to set the time table for clinical diagnosis of developmental retardation by making a comparative study of normal developmental children so we can treat the children with autistic disorder in good time. Method We made the comparative study of interview sheets recorded by parents of total 163 children who were diagnosed as autistic disorder who visited HaeMa Oriental Medical Clinic with interview sheets recorded by parents of generally accepted normal developmental children(263) and then we took statistics. Results : 1. There was significant correlation with speech and walking among five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲) in autistic disorder statistically and clinically in comparison with normal children. 2. There wasn't significant correlation with growth time of tooth among five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲) on diagnosis of autistic disorder in comparison with normal children. 3. There was significant correlation with retardation of times going to toilet by oneself (it does not consist in five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲).) in both of autistic disorder. Conclusion Autistic disorder was significantly correlated with the faculty of speech(語遲), retardation in walking out(行遲) of five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲). We need to concrete the index of diagnosis, because it is so difficult to measure times and register retardation in tooth eruption(齒遲), retardation in hair-growing(髮遲), debility of neck and nape(頭項軟), flaccidity of extremities(手軟) and flaccidity of muscle(肌肉軟). And we can also use times going to toilet by oneself as one of diagnostic criteria because of its significant correlation. It is required to make early diagnosis of five kinds of flaccidity in infants(五軟), five kinds of retardation(五遲) using these criteria, and to treat them early by oriental medicine.