• Title/Summary/Keyword: Chil-chung

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Syntheses of New Lactones Containing Phenyl or Methyl Groups (페닐기 및 메틸기를 포함하는 새로운 lactone의 합성)

  • Chang, Seung Hyun;Moon, Sang Chil;Kim, Hak Hee;Lee, Kap Duk;Chung, Kwang Bo
    • Applied Chemistry for Engineering
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    • v.9 no.6
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    • pp.842-845
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    • 1998
  • Four new lactones and one dibenzo crown ether were synthesized by reaction of dihydroxy compound with oxalyl chloride and with ${\alpha}$,${\omega}$-dibromo compound, respectively. 5,6,11,12-Tetracarbonyl-2,2,3,3,8,8,9,9-octaphenyl-1,4,7,10-tetraoxacyclodode- cane(1), 5,6,11,12-tetracarbonyl-2,2,3,3,8,8,9,9-octamethyl-1,4,7,10-tetraoxacyclododecane(2), 7,8,15,16-tetracarbonyl-1,6,9,14-tetraoxacylclohexadecane(3), and 5,6,11,12-tetracarbonyl- 2,3,8,9- tetraphenyl-1,4,7,10-tetraoxacyclododecane(4) were prepared by reaction of oxalyl chloride with benzopinacol, pinacol, 2,2'-dihydroxybiphenyl and hydrobenzoin, respectively, in the presence of pyridine. Dibenzo-13-crown-4 (5) was obtained by reaction of catechol with 1,3-dibromopropane/1,2-dibromoethane.

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Maffucci Syndrome Enchondromatosis of Hand with Hemangioma of Scalp A Case Report (Maffucci 증후군 수부의 내연골종증에 동반된 두부의 혈관종 증례보고)

  • Chung, Kyung-Chil;Kim, Key-Yong;Choi, Jang-Suk;Kim, Jin-Seok
    • The Journal of the Korean bone and joint tumor society
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    • v.11 no.2
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    • pp.208-212
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    • 2005
  • Maffucci syndrome was first reported by Maffucci, an Italian, in 1881. This rare, nonhereditary syndrome is characterized by multiple enchondromas combined with hemangiomas and less commonly lymphangiomas. Maffucci syndrome is sometimes confused with Ollier disease, which was described in 1899 and consists of multiple enchondromas without hemangiomas. Although the prevalence of malignant change in skeletal lesions in Maffucci syndrome and Ollier disease is quite similar, it is important to differentiate between these two conditions because of the greater risk of developing nonmusculoskeletal malignancies in the former. We experienced a case of this rare syndrome and because of it's rarity, we report with review of literature.

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An Antitumor Constituent of the Cultured Mycelia of Hydnum repandum (턱수염 버섯 배양(培養) 균사(菌絲)의 항종양(抗腫瘍) 성분(成分))

  • Chung, Kyeong-Soo;Choi, Eung-Chil;Kim, Byong-Kak;Kim, Yang-Sup
    • The Korean Journal of Mycology
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    • v.11 no.2
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    • pp.91-95
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    • 1983
  • To investigate antitumor constituents of Hydnum repandum, which belongs to edible basidiomycetes, the mycelia separated from the carpophore were shake-cultured and subjected to hot water extraction. The extract was concentrated under vacuum and mixed with a three-fold volume of 95% ethanol to yield precipitates. The water soluble fraction of the precipitates was dialyzed and then lyophilized to yield a water soluble protein-polysaccharide fraction (= WPPF). This exerted antitumor activity against sarcoma 180 implanted in ICR mice. When administered i.p. at the dose level of 20mg/kg once daily for ten consecutive days, it showed an inhibition ratio of 54.3%. WPPF was found to be composed of a polysaccharide moiety (42% of WPPF) and a protein moiety (28% of WPPF) when determined by colorimetric method using anthrone reagent and Folin's phenol reagent. The polysaccharide moiety of WPPF was found to contain glucose (57.4%), mannose(19.3%), galactose (10.8%), xylose (6.8%), and fucose (5.7%), when the methanolysate of WPPF was analysed by GLC method.

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Giant Cell Tumor of the Cervical Spine - Case Report - (경추에 발생한 거대 세포종 - 증례 보고 -)

  • An, Ki-Chan;Chung, Kyung-Chil;Kim, Yoon-Jun
    • The Journal of the Korean bone and joint tumor society
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    • v.12 no.1
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    • pp.57-62
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    • 2006
  • Giant cell tumors are potentially malignant tumors in vertebrae, affecting frequently difficult to diagnose and are often inoperable. So it will be treated using radiation because of their high recurrence rate and the mechanical compression of spinal cord, but many surgeons described tumors of the vertebra, and the affected vertebral body can be treated using radical or near to total excision, with anteroposterior vertebral fusion or instrumentation of the spine. we report a case of giant cell tumor affecting the third cervical vertebra which caused neck pain and destroyed the vertebra body had treated using radical excison with fusion of posterior arch using instrumentation of the spine together with a literature review.

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Studies on the constituents of higher fungi of Korea

  • Kim, Byong-Kak;Choi, Eung-Chil;Chung, Kyeong-Soo;Kang, Chang-Yul;Kim, Sook-Hee;Kim, Jin-Sook;Kim, You-Jin;Lee, Kyong-Lim;Lee, Jong-Kil
    • Archives of Pharmacal Research
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    • v.5 no.1
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    • pp.21-23
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    • 1982
  • To develop new potent antitumor substancces with low toxicity from natural products, especially from higher fungi of Korea, the carpophores of some wild basidiomycetes were collected and the antitimor test for their polysaccharides was done. The dried carpophores were extracted with hot water, and from the extracts, crude polysaccharides were obtained by alcohol precipitation. The alcohol precipitated crude polysaccharides were partially purified by dialysis and then used as the samples for antitumor tests. Among tested, the polysaccharide of Laccaria laccata, Trametes sanguineus, Armlliariella mellea, Clitocybe in fundibuliformis, and Xeromphalina campanella respectively showed the inhibition ratio of 75%, 72%, 94% 55%, and 47% when administered i. p. once dailly for ten days at the dose level of 20mg/kg/day into the mice implanted with $10^{6}$ cells of sarcoma 180/mouse. However, those of Craterellus cornucopiodes, Daedaleopsis confrogosa, and Coriolus sp. showed almost no activities.

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Studies on Antibiotic Producers of Korean Soil Microbes(II) -Isolation and Antibiotic Activity of Streptomyces Strain DMC-64- (한국(韓國) 토양균(土壤菌)중 항생물질(抗生物質) 생성균(生成菌)에 관한 연구(硏究)(제 2 보)(第 2 報) -스트렙토마이세스속(屬) 균주(菌株) DMC-64 호(號)의 분리(分離) 및 항균작용(抗菌作用)-)

  • Kim, Jung-Woo;Choi, Eung-Chil;Kim, Byong-Kak
    • The Korean Journal of Mycology
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    • v.12 no.3
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    • pp.85-92
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    • 1984
  • To isolate antibiotic-producing microorganisms from Korean soils, microbes were isolated from the soil samples and screened for antibacterial activity. A strain which was isolated from the soil sample collected in Choong Chung Book Do had a high antibacterial activity against gram-positive bacteria. The examination of morphological and physiological characteristics of that strain according to the International Streptomyces Project methods showed that it was one of Streptomyces species. After the antibacterial constituent of the strain was produced in submerged culture method, it was isolated and purified by XAD-2 and CM-Sephadex column chromatography. And it was found to be one of quinone type antibiotics.

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Studies on the Effects of Injected Amount of I131 in Uptake and Release Rate by Thyroid in Guinea Pigs 1. On the Influence of Injected Amount of Redioiodine-131 in Uptake and Release Rate by Thyroid in Male Guinea Pigs (방사성옥도(放射性沃度)(I131)의 주입량(注入量)이 기니픽 갑상선(甲狀腺)에의 섭취(攝取) 및 방출률(放出率)에 미치는 영향(影響)에 관(關)한 연구(硏究) 제(第)1보(報) 방사성옥도(放射性沃度)(I131)의 주입량(注入量)이 웅(雄)기니픽 갑상선(甲狀腺)에서의 섭취(攝取) 및 방출률(放出率)에 미치는 영향(影響))

  • Chung, Yung Chai;Shim, Sang Chil;Lee, Heung Shik
    • Korean Journal of Veterinary Research
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    • v.6 no.1
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    • pp.24-30
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    • 1966
  • In order to observe the effect of the injected radioactive iodine-$I^{131}$ on the uptake in thyroid of normal male guinea pigs and P.B.$I^{131}$ conversion ratio of $I^{131}$ in serum, 24 matured male guinea pigs were divided in 4 groups and $35{\mu}c$, $70{\mu}c$, $140{\mu}c$ and $280{\mu}c$ per kg of body weight respectively were injected subcutaneously. 1. The uptake rates of radioactveiodine-$I^{131}$ by external counts of thyroidal uptake reached the maximum level of uptake in 24 hours after injection. 2. As the injected amount increases, the uptake rates of maximum levels and release rate were increased. 3. Uptake rate in the removed thyroid have shown no statistical in the $35{\mu}c$ and $70{\mu}c$ groups of injected guinea pigs. 4. There was no statistical significance in $140{\mu}c$ and $280{\mu}c$ groups of injected guinea pigs. 5. P.B.$I^{131}$ conversion ratio of $I^{131}$ in serum was not in proportion to injected amounts: 61.0%(35), 70.2%(70), 75.3%(140) and 64.8%(280).

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Estimating Surface Orientation Using Statistical Model From Texture Gradient in Monocular Vision (단안의 무늬 그래디언트로 부터 통계학적 모델을 이용한 면 방향 추정)

  • Chung, Sung-Chil;Choi, Yeon-Sung;Choi, Jong-Soo
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.26 no.7
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    • pp.157-165
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    • 1989
  • To recover three dimensional information in Shape from Texture, the distorting effects of projection must be distinguished from properties of the texture on which the distortion acts. In this paper, we show an approximated maximum likelihood estimation method in which we find surface orientation of the visible surface (hemisphere) in gaussian sphere using local analysis of the texture. In addition, assuming that an orthogonal projection and a circle is an image formation system and a texel (texture element) respectively, we drive the surface orientation from the distribution of variation by means of orthogonal projection of a tangent direction which exists regularly in the arc length of a circle. We present the orientation parameters of textured surface with slant and tilt in gradient space, and also the surface normal of the resulted surface orientationas as needle map. This algorithm is applied to geographic contour (artificially generated chejudo) and synthetic texture.

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A RETROSPECTIVE CLINICAL STUDY OF PERIAPICALLY INFECTED TEETH TREATED WITH PERIAPICAL SURGERY (치근단 감염 치아의 치근단 수술 후 예후에 관한 후향적 연구)

  • Kim, Hyeon-Min;Park, Chul-Hwi;Lee, Sang-Chil;Kim, Dong-Woo;Park, Dae-Song;Jung, Jin-Hwan;Lee, Seul-Ki;Song, Min-Seok
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.32 no.3
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    • pp.236-241
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    • 2010
  • Purpose: The purpose of this retrospective clinical study was to monitor the outcomes of periapical surgery in periapically infected tooth with or without retrograde filling materials (MTA or IRM). Patients and Methods: A total of 85 teeth in 63 patients were included in the study between November 2004 and August 2008. Randomly, MTA or IRM was used as a retrograde filling material or only apical resection without retrograde filling. Teeth with advanced periodontal bone loss or presence of root fracture were excluded from the study. The patients were subjected to a minimum follow-up period of 12 months, with a mean of 17.1 months. Results: Successful healing was observed in 83.3% of the MTA-treated teeth, 80% of the IRM-treated teeth and 75% of the teeth which was not retrograde filling. Doubtful healing was seen 9.3% (MTA), 13.3% (IRM), 12.5% (no retro-filling). The success rate of upper incisors (92%) was higher than lower lincisor and molars (66.7% and 50%, respectively). Conclusion: In this study, periapical surgery including retrograde filling improves the prognosis. And, no statistically significant differences were found between retrograde filling materials (MTA or IRM).

Development of Remote Control System for KNUO 16 (공주대학교 천문대 16인치 반사망원경의 원격 제어 시스템 구축)

  • Kim, Chil-Young;Chung, Jung-In;Kim, Jong-Hun;Kim, Hyouk;Jang, Bi-Ho;Kim, Hee-Soo
    • Journal of the Korean earth science society
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    • v.24 no.5
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    • pp.456-466
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    • 2003
  • We developed a remote control system for the 16" reflecting telescope at KNUO (Kongiu National University Observatory). This system is a close loop system. The electronic control part used TCS-196 of the Korea Astronomy Observatory, the mechanical part was developed directly in this research. The pointing accuracy of this system was ${\pm}$50" in the hour angle direction, ${\pm}$40" in the declination direction after mount modeling. The tracking accuracy was about 1"/min. This pilot test result means that this system is suitable for research or education of astronomical fields.