• Title/Summary/Keyword: Chemical constituents

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Chemical Constituents and Biological Activities of Cichorium intybus L.

  • El-Lakany, Abdalla M.;Aboul-Ela, Maha A.;Abdul-Ghani, Mohamed M.;Mekky, Hattem
    • Natural Product Sciences
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    • v.10 no.2
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    • pp.69-73
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    • 2004
  • Continuation of a phytochemical study of Cichorium intybus L. (Astraceae) growing in Egypt, resulted in the isolation and identification of a new sesquiterpene lactone 3,4-dihydrolactucin, in addition to the eight known compounds; kaempferol, isoscutellarin, cichoriin, umbelliferone, lupeol, lupeol acetate, ${\beta}-sitosterol$, and ${\beta}-sitosterol-3-O-glucoside$. Chemical structures of the isolated compounds were assigned based on different physical, chemical, and spectroscopic techniques including IR, UV, MS, 1D- and 2D-NMR spectra. Furthermore, the antimicrobial, and spasmogenic activities of some fractions and isolates were also assessed.

Ethnopharmacology, bioactivities and chemical constituents of some anti-cancer plants in Malaysia

  • Chooi, Ong-Hean
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 1999.10a
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    • pp.90-109
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    • 1999
  • Many plant species are used in Malaysia in folk medicine for the treatment of cancer. This paper presents some of these species with details on other ethnopharmacological uses, the known bioactivities and some chemical constituents of each of the species given. It is normal practice in traditional medicine that one species of plant is used to treat various ailments. Thus the plant species listed are all used to treat cancer but have various other ethnophrmacological uses as well, some with few other uses and rest with many other uses. Information on bioactivities of each species resulting from tests on human and experimental animals are also given. Proven bioactivities give strength to ethnopharmacological claims on the efficacies of plant resources in the treatment of cancer and various other ailments but will but will not necessarily lead to the production of new pharmaceutical drugs. Many of the known chemical constituents of each species are given. This shows the richness and variety of chemicals containes in each of the species listed, The chemicals listed may or may not prove to be important in the pharmaceutical sciences but is an indication of what each species contatin in thrms of plant chemicals, It is a well known fact that many of the pharmaceutical prescriptions in present day use are of plant origin and semi-synthetic or fully synthetic chemicals produced using knowledge gained from studies of phytochemicals. Thus the paper presented will give useful information and also shows the richness of plant species that have high potentials for the development of anti-cancer resources from plants in Malaysia.

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Studies on the Chemical Constituents of the Tea Leaf (차엽(茶葉)의 성분(成分)에 관(關)한 연구(硏究))

  • Kim, Kwan
    • Korean Journal of Food Science and Technology
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    • v.9 no.1
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    • pp.10-12
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    • 1977
  • Chemical constituents and amino acid contents of tea leaves which were harvested three times (May, July and August) from the tree at two different locations were studied. The contents of total nitrogen, ascorbic acid and amino acid decreased, while those of fiber and tannin increased in the order of May, July and August crops. No differences were observed in the contents of reducing sugar, caffeine and ash among tea leaves harvested at different times. There were no effects of locations on the contents of chemical constituents of tea leaves.

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Chemical Constituents from the Root of Brassica campestris ssp rapa (순무(Brassica campestris ssp rapa) 뿌리의 화학성분)

  • Kim, Jung-Sook;Choi, Yeon-Hee;Seo, Jee-Hee;Lee, Jung-Won;Kim, Young-Sup;Ryu, Shi-Yong;Kang, Jong-Seong;Kim, Young-Kyoon;Kim, Sung-Hoon
    • Korean Journal of Pharmacognosy
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    • v.35 no.3 s.138
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    • pp.259-263
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    • 2004
  • Twelve constituents were isolated from the MeOH extract of the root of Brassica campestris L. ssp rapa. They were identified as linoleic acid methylester (1), palmitic acid (2), ${\beta}-sitosterol$ (3), 1-methoxyindole-3-acetonitrile (4), indole-3-acetonitrile (5), linolenic acid (6), goitrin (7),4-hydroxycinnamyl alcohol (8), coniferyl alcohol (9), p-coumaroylglucose (11) and feruloylglucose (12), on the basis of spectral data respectively.

GC/MS analysis of volatile constituents from woody plants (목본성 식물의 휘발성 성분 GC/MS 분석)

  • Lee, Dong-Gu;Choi, Kyung;Lee, Sang-Hyun
    • Korean Journal of Agricultural Science
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    • v.38 no.4
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    • pp.723-730
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    • 2011
  • To search for the new development of industrial application of woody plants, the chemical composition of the volatile constituents from woody plants (Evodia daniellii, Clerodendron trichotomum, Prunus padus, and Zanthoxylum ailanthoides) was determined by GC and GC/MS spectrometric analysis with the aid of NBS, Wiley Library and RI indice searches. The major constituents were t-ocimene from the leaves of E. daniellii, linalool from the leaves of C. trichotomum, benzaldehyde from the leaves and twigs of P. padus, ${\beta}$-thujene from the leaves of Z. ailanthoides, and 2-undecanone from the stems of Z. ailanthoides. These results suggested that the major volatile constituents of woody plants could be a useful lead compound in the development of functional materials for industrial application.

Changes in ${\gamma}-Aminobutyric$ Acid(GABA) and the Main Constituents by a Treatment Conditions and of Anaerobically Treated Green Tea Leaves (혐기처리 녹차의 처리조건에 따른 ${\gamma}-Aminobutyric$ Acid(GABA) 및 주요 성분의 변화)

  • Chang, Ji-Shin;Lee, Byong-Soon;Kim, Young-Gul
    • Korean Journal of Food Science and Technology
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    • v.24 no.4
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    • pp.315-319
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    • 1992
  • Korean green tea leaves which were harvested three times(May, June, August) were treated with anaerobic conditions and were measured changes of ${\gamma}-aminobutyric$ acid(GABA) and other constituents. In anaerobically treated green tea leaves, the content of ${\gamma}-aminobutyric$ acid(GABA) and alanine increased while glutamic acid decreased. Whereas theanine, arginine, caffeine and tannin showed little change and the content of vitamine C slightly decreased with the passing of the anaerobic treatment time. Formation of GABA, a hypotensive constituents, was proportioned to the content of glutamic acid and the optimum time of the anaerobic treatment was about 12 hours. In the anaerobic treatment of green tea leaves, effect of nitrogen gas and vacuum condition was no difference between two.

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Studies on the Constituents of Korean Valerians ( II ) -Studies on the Constituents of the Underground Portion of Valeriana fauriei var. dasycarpa $H_{ARA}$- (국산 쥐오줌풀속 식물의 성분 연구( II ) -광릉쥐오줌풀의 성분 연구-)

  • Kim, Chang-Min;Ryu, Kyung-Soo
    • Korean Journal of Pharmacognosy
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    • v.8 no.3
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    • pp.95-101
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    • 1977
  • Substance A, white prismatic crystal, mp $134{\sim}135,\;C_{29}H_{50}O$, substance B, white needle crystal, mp $131{\sim}132^{\circ},\;C_{17}H_{28}O_4$ and substance C colorless oils, bp $84{\sim}85,\;C_{15}H_{24}O$ were isolated from the underground portion of Valeriana fauriei var. dasycarpa $H_{ARA}$(Valerianaceae) according to Thies method. Substance A was confirmed as known sterol, ${\beta}-sitosterol$ by chemical and spectral discussions. Substance B was estimated as hitherto unknown sesquiterpenoid, 11-acetoxylhydroxyvaleranone by chemical and spectral discussions. Substance C was proposed as hitherto unknown sesquiterpenoid 1, 4-dimethyl-7-isopropenyl 4, 5, 6, 8, 9, 10-hexahydroazulene-1-ol by chemical and spectral discussions, and the general biogenetic considerations.

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Chemical Constituents and Their Acetylcholinesterase Inhibitory Activity of Underground Parts of Clematis heracleifolia (조희풀(Clematis heracleifolia) 지하부의 성분과 Acetylcholinesterase억제 활성)

  • Kim, Mi Ae;Kim, Myong Jo;Chun, Wanjoo;Kwon, Yongsoo
    • Korean Journal of Pharmacognosy
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    • v.46 no.1
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    • pp.6-11
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    • 2015
  • To clarify chemical constituents of Clematis heracleifolia, isolation and structure elucidation of the underground parts of C. heracleifolia were performed. Five compounds were isolated from $CHCl_3$ and n-BuOH soluble fraction of this plant. On the basis of spectral and physico-chemical data, the structure of isolated compounds were identified as coniferyl alcohol (1), scoparone (2), (+)-lariciresinol (3), phytosterols (4), and daucosterol (5), respectively. All compounds are isolated from this plant for the first time. To evaluate anti-acetylcholinesterase activity of the isolated compounds, compounds 1, 2, 3, and 5 were tested inhibition activity against acetylcholinesterase. Among tested compounds, daucosterol (5) showed acetylcholinesterase inhibitory activity with $IC_{50}$ value of $6.1{\mu}M$.

Enhanced Yield of Extraction from Gastrodia elata Blume by Ultrasonication and Enzyme Reaction

  • Kim, Hyun-Jong;Kwak, In-Seob;Lee, Bong-Soo;Oh, Seung-Bae;Lee, Hyun-Chul;Lee, Eun-Mi;Lim, Ja-Young;Yun, Yeoung-Sang;Chung, Bong-Woo
    • Natural Product Sciences
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    • v.11 no.3
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    • pp.123-126
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    • 2005
  • Gastrodia elata Blume (Chunma) belongs to Orchidaceae, which is a perennial parasitic herbaceous plant and grows in the woods of the central provinces of China, Korea and Japan. Recently, the constituents of the tubers of this plant have been investigated by researchers who have revealed the presence of phenolic compounds including gastrodin as a major constituent, together with 4-hydroxybenzaldehyde, 4-hydroxybenzyl alcohol, parishin, 4,4-dihydroxybenzyl sulfoxide, vanillin, vanillyl alcohol, beta-sitosterol, organic acids and polysaccharides, etc. In this study, we used ultrasonicator and two kinds of enzymes for enhancement of extraction yield. We also used electronic nose for the aroma pattern analysis of Chunma extracts. The concentrations of glucose and functional constituents (gastrodin, vanillin, 4-hydroxybenzaldehyde and 4-hydroxybenzyl alcohol) were measured by biochemistry analyzer and HPLC, respectively. Therefore, we showed that the yield of extraction was increased and discomfortable odor was reduced.