• Asia Marketing Journal
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• 제8권3호
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• pp.123-139
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• 2006

창사 이래 한국 광고 업계를 선도해 온 제일기획의 성공 전략은 크게 다음의 세 가지로 정리될 수 있다. 첫째는 클라이언트의 브랜드 자산을 극대화하는 통합적 브랜드 관리 시스템, 둘째는 창의적 완성도를 극대화하는 크리에이티브 전략, 그리고 셋째는 체계적인 소비자 조사 결과를 바탕으로 한 과학적 미디어 전략이다. 본 사례에서는 제일기획의 성공 전략을 다각적으로 검토해 보고 변화하는 환경 속에서 지속적인 경쟁력 강화를 통해 클라이언트에게 높은 고객 가치를 창출해 온 제일기획의 노력상을 조명해 본다.

• Clinical and Experimental Reproductive Medicine
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• 제39권1호
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• pp.10-14
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• 2012

The ovarian follicles develop initially from primordial follicles. The majority of ovarian primordial follicles are maintained quiescently as a reserve for the reproductive life span. Only a few of them are activated and develop to an advanced follicular stage. The maintenance of dormancy and activation of primordial follicles are controlled by coordinated actions of a suppressor/activator with close communications with somatic cells and intra-oocyte signaling pathways. Many growth factors and signaling pathways have been identified and the transforming growth factor-beta superfamily plays important roles in early folliculogenesis. However, the mechanism of maintaining the dormancy and survival of primordial follicles has remained unknown for decades. Recently, since the first finding that all primordial follicles are activated prematurely in mice deficient forkhead box O3a, phosphatidylinositol 3 kinase/phosphatase and tensin homolog (PTEN) signaling pathway was reported to be important in the regulation of dormancy and initial follicular activation. With these informations on early folliculogenesis, clinical application can be expected such as in vitro maturation of immature oocytes or in vitro activation of follicles by PTEN inhibitor in cryopreserved ovarian cortical tissues for fertility preservation.