• Asian Pacific Journal of Cancer Prevention
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• v.16 no.4
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• pp.1403-1407
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• 2015

Background: New tumour biomarkers are being intensely investigated for malignant mesothelioma (MM). Fibulin-3 is produced in MM but its role remains uncertain. The aim of this study was to evaluate the validity of measuring serum fibulin-3 in the diagnosis and prognosis of MM. Materials and Methods: This prospective study was performed on 43 patients and 40 healthy controls who were admitted to our hospital between January 2012 and January 2014. Data from MM patients, including demographic and clinical features, routine laboratory data, levels of serum fibulin-3, and treatment outcomes were defined as potential prognostic factors. The receiver operating characteristic (ROC) curve for fibulin-3 was used to detect the cut-off value with highest sensitivity and specificity. Univariate survival analysis was performed using the Kaplan-Meier method in patients with MM. Afterwards, the possible factors identified with univariate analyses were entered into the cox regression analysis. Results: Our results revealed that patients with MM had significantly higher serum levels of fibulin-3 than controls. The results showed that the best cut-off point was 36.6 ng/ml with an AUC (area under the curve)=0.976, sensitivity=93.0% and specificity=90.0. In our study, the initial significant poor prognostic factors were advanced stage, high white blood cell count, high platelet count, high C-reactive protein (p<0.05 for each variable). Later, according to multivariate analysis the results showed only advanced stage as significant parameter (p=0.040). Conclusions: We determined that real use for serum fibulin-3 was not for prognosis but for diagnosis in MM. Also advanced stage was associated with poor MM prognosis.

• Journal of Broadcast Engineering
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• v.25 no.1
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• pp.25-35
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• 2020

Recently, the development of image processing technology, as well as hardware performance, has been continuing the research on 3D point processing technology that provides users with free viewing angle and stereoscopic effect in various fields. Point cloud technology, which is a type of representation of 3D point, has attracted attention in various fields because it can acquired/expressed point precisely. However, since Hundreds of thousands, millions of point are required to represent one 3D point cloud content, there is a disadvantage that a larger amount of storage space is required than a conventional 2D content. For this reason, the MPEG (Moving Picture Experts Group), an international standardization organization, is continuing to research how to efficiently compress, store, and transmit 3D point cloud content to users. In this paper, a V-PCC bitstream generated by a V-PCC (Video-based Point Cloud Compression) encoder proposed by the MPEG-I (Immersive) group is composed of an MPU (Media Processing Unit) defined by the MMT. In addition, by extending the signaling message defined in the MMT standard, a parameter for a segmented transmission method of the 3D point cloud content by area and quality parameters considering the characteristic of the 3D point cloud content, so that the quality parameters can be selectively determined according to the user's request. Finally, in this paper, we verify the result through design/implementation of the verification platform based on the proposed technology.

• Journal of Korea Water Resources Association
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• v.37 no.11
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• pp.897-913
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• 2004

There has been continuous efforts to manage the water resources for the required water quality criterion at river channel in Korea. However, we could not obtain the partial improvement only for the point source pollutant such as, wastewater from urban and industrial site through the water quality management. Therefore, it is strongly needed that the Best Management Practice(BMP) throughout the river basin for water quality management including non-point source pollutant loads. This problem should be resolved by recognizing the non-point source pollutant loads from upstream river basin to the outlet depends on the land use and soil type characteristic of the river basin using the computer simulation by distributed parameter model based on the detailed investigation and the application of Geographic Information System(GIS). Used in this study, Annualized Agricultural Non-Point Source Pollution (AnnAGNPS) model is a tool suitable for long term evaluation of the effects of BMPs and can be used for un gauged watershed simulation of runoff and sediment yield. Now applications of model are in progress. So we just describe the limited result. However If well have done modeling and have investigated of propriety of model, well achieve our final goal of this study.

• Journal of the Korea institute for structural maintenance and inspection
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• v.19 no.1
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• pp.45-52
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• 2015

Fiber-reinforced polymer (FRP) has been generally accepted by civil engineers as an alternative for steel reinforcing bars (rebar) due to its advantageous specific tensile strength and non-corrosiveness. Even though some glass fiber reinforced polymer (GFRP) rebars are available on a market, GFRP is still somewhat uncompetitive over steel rebar due to their high cost and relatively low elastic modulus, and brittle failure characteristic. If the price of component materials of GFRP rebar is not reduced, it would be another solution to increase the performance of each material to the highest degree. The tensile strength generally decreases with increasing diameter of FRP rebar. One of the reasons is that only fibers except for fibers in center resist the external force due to the lack of force transfer and the deformation of only outer fibers by gripping system. Eliminating fibers in the center, which do not play an aimed role fully, are helpful to reduce the price and finally FRP rebar would be optimized over the price. In this study, the effect of the hollow section in a cross-section of a GFRP rebar was investigated. A GFRP rebar with 19 mm diameter was selected and an analysis was performed for the tensile test results. Parameter was the ratio of hollow section over solid cross-section. Four kinds of hollow sections were planned. A total of 27 specimens, six specimens for each hollow section and three specimens with a solid cross-section were manufactured and tested. The change by the ratio of hollow section over solid cross-section was analyzed and an optimized cross-section design was proposed.

• Journal of the Korea Concrete Institute
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• v.21 no.5
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• pp.589-597
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• 2009

High Performance Fiber-reinforced Cement Composite (HPFRCC) shows the multiple crack and damage tolerance capacity due to the interfacial bonding of the fibers to the cement matrix. For practical application, it is needed to investigate the fractural behavior of HPFRCC and understand the micro-mechanism of cement matrix with reinforcing fiber. This study is devoted to the investigation of the AE signals in HPFRCC under monotonic and cyclic uniaxial compressive loading, and total four series were tested. The major experimental parameters include the type and volume fraction of fiber (PE, PVA, SC), the hybrid type and loading pattern. The test results showed that the damage progress by compressive behavior of the HPFRCC is a characteristic for the hybrid fiber type and volume fraction. It is found from acoustic emission (AE) parameter value, that the second and third compressive load cycles resulted in successive decrease of the amplitude as compared with the first compressive load cycle. Also, the AE Kaiser effect existed in HPFRCC specimens up to 80% of its ultimate strength. These observations suggested that the AE Kaiser effect has good potential to be used as a new tool to monitor the loading history of HPFRCC.

• Journal of Korean Society of Environmental Engineers
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• v.38 no.4
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• pp.184-192
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• 2016

A profiling monitoring system has been developed to monitor the water quality variations according to each water depth and applied for a test-bed. The key parameters were derived to disclose the aquatic ecology and environment of river systems, and the real-time monitoring techniques to profile the variations of each parameter were verified. Monitoring parameters were configured to include water quality, hydrodynamic, and weather conditions. Considering the water depth of the 4 major rivers in Korea, a profiling monitoring system with 1.0 m water depth interval for each monitoring has been established. To understand the real-time variation properties in the Han river, the monitoring system has been installed and operated at the YangHwa-Dock as a test-bed. Based on the results of the detailed analyses on the spring season, as the characteristic diurnal and water-depth-related variations for water temperature, pH, dissolved oxygen (DO), and chlorophyll-a were observed, it could be concluded that the real-time water-depth profiling monitoring system is a very effective tool for the proper management of river environment.

• Journal of Korean Society of Transportation
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• v.33 no.4
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• pp.393-404
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• 2015

Gravity model has had the major problem that the model explains the characteristics of travel behavior with only deterrence factors such as travel time or cost. In modern society, travel behavior can be affected not only deterrence factors but also zonal characteristics or transportation service. Therefore, those features have to be considered to estimate the future travel demand accurately. In this regard, there are two primary aims of this study: 1. to identify the characteristics of inter-zonal travel, 2. to develop the new type of calibration method. By employing accessibility variable which can explain the manifold pattern of trip, we define the zonal travel behavior newly. Furthermore, we suggest 2-phase calibration method, since existing calibration method cannot find the optimum solution when organizing the deterrence function with the new variables. The new method proceeds with 2 steps; step 1.estimating deterrence parameter, step 2. finding balancing factors. The validation results with RMSE, E-norm, C.R show that this study model explains the inter-zonal travel pattern adequately and estimate the O/D pairs precisely than existing gravity model. Especially, the problem with estimation of short distance trip is overcomed. In conclusion, it is possible to draw the conclusion that this study suggests the possibility of improvement for trip distribution model.

• Journal of the Korean Society of Radiology
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• v.1 no.1
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• pp.25-30
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• 2007

ROC(Receiver Operating Characteristic)curve is the method that estimate detected insignificant signal from the human's sense of sight, it has been raised excellent results. In this study, we evaluate image quality and equipment character by obtaining a chest image from CR(Computed Radiography) and DDR(Direct Digital radiography) using the human chest phantom, The parameter of exposure for obtaining chest image was 120 kVp/3.2 mAs and the SID(Source to Image Distance) was 180cm. The images were obtained by CR(AGFA MD 4.0 General plate, JAPAN) and DDR(HOLOGIC nDirect Ray, USA). Using some pieces of Aluminum and stone for expressing regions, then attached them on the heart, lung and thoracic vertebrae of the phantom. 29 persons hold radiology degrees were participated in ROC analysis. As a result of the ROC analysis, TPF(true positive fraction) and FPF(false positive fraction) of DDR and CR are 0.552 and 0.474 and 0.629 and 0.405, respectively. By using the results, the ROC curve of CR has higher image quality than DDR. According to the theory, DDR has the higher image quality than CR in chest X-ray image. But, CR has the higher image quality than DDR. quality of DDR inserted the enhance board. The results confirmed that image post-processing is important element decipherment of clinical.

• Journal of Korea Water Resources Association
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• v.47 no.2
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• pp.171-182
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• 2014

The objective of this study is to evaluate the utilization of bivariate joint drought index in South Korea. In order to develop the bivariate joint drought index, in this study, Clayton copula was used to estimate the joint distribution function and the calibration method was employed for parameter estimation. Precipitation and soil moisture data were selected as input data of bivariate joint drought index for period of 1977~2012. The time series analysis, ROC (Receiver Operating Characteristic) analysis, spatial analysis were used to evaluate the bivariate joint drought index with SPI (Standardized Precipitation Index) and SSI (Standardized Soil moisture Index). As a result, SPI performed better for drought onset and SSI for drought demise. On the other hand the bivariate joint drought index captured both drought onset and demise very well. The ROC score of bivariate joint drought index was higher than that of SPI and SSI, and it also reflected the local drought situations. The bivariate joint drought index overcomes the limitations of existing drought indices and is useful for drought analysis.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.25 no.4
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• pp.207-218
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• 2013

This study is based on a series of numerical modeling experiments to understand the circulation and its change in the Chunsu Bay (CSB), Yellow Sea of Korea. A skill analysis was performed for the tidal height and tidal current of the observation data using the amplitude and phase of the 4 major tidal constituents respectively for verification of modeling experimental results. As a result, most of the skill score was seen to be over 90%, so numerical model experiment results can be said to be in good agreement with the observed tidal height and tidal current. Tidal wave proceeded from the entrance of the CSB towards inside, and the tidal range gradually increased to the north. It took about 10 to 30 minutes for the tidal wave to reach to northern end. The tidal wave showed a characteristic to rotate counter-clockwise in the southern part. The tidal current flowed to the north-south direction along the bottom topography; the angle of the major axis appeared alongside the isobath. It showed the characteristics of reversing tidal current with the minor axis less than 10% of the major axis. The strength of the tidal residual current that is influenced by geographical factors including bathymetry and coastline showed the range of 1~30 cm/sec, greater in the south channel and smaller in northern Bay. Two pairs of cyclonic/anti-cyclonic eddies around Jukdo and 3~4 pairs of strong eddies at the southern part of CSB in hundreds of m to a few km size by relative vorticity derived from the tidal residual current.