• Title/Summary/Keyword: Channel management

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The Effect of Tyrosine Kinase Inhibitors on the L-type Calcium Current in Rat Basilar Smooth Muscle Cells

  • Bai, Guang-Yi;Yang, Tae-Ki;Gwak, Yong-Geun;Kim, Chul-Jin
    • Journal of Korean Neurosurgical Society
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    • v.39 no.3
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    • pp.215-220
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    • 2006
  • Objective : Tyrosine kinase inhibitors may be useful in the management of cerebral vasospasm. It has not yet been reported whether L-type $Ca^{2+}$ channels playa role in tyrosine kinase inhibitors-induced vascular relaxation of cerebral artery. This study was undertaken to clarify the role of L-type $Ca^{2+}$ channels in tyrosine kinase inhibitors-induced vascular relaxation, and to investigate the effect of tyrosine kinase inhibitors on L-type $Ca^{2+}$ channels currents in freshly isolated smooth muscle cells from rat basilar artery. Methods : The isolation of rat basilar smooth muscle cells was performed by special techniques. The whole cell currents were recorded by whole cell patch clamp technique in freshly isolated smooth muscle cells from rat basilar artery. Results : Patch clamp studies revealed a whole-cell current which resembles the L-type $Ca^{2+}$ current reported by others. The amplitude of this current was decreased by nimodipine and increased by Bay K 8644. Genistein[n=5], tyrphostin A-23[n=3]. A-25[n=6] $30{\mu}M$ reduced the amplitude of the L -type $Ca^{2+}$ channel current in whole cell mode. In contrast, diadzein $30{\mu}M$ [n=3]. inactive analogue of genistein, did not decrease the amplitude of the L-type $Ca^{2+}$ channels current. Conclusion : These results suggest that tyrosine kinase inhibitors such as genistein, tyrphostin A-23, A-25 may relax cerebral vessel through decreasing level of intracellular calcium, [$Ca^{2+}$]i, by inhibition of L-type $Ca^{2+}$ channel.

Analysis of the MSC(Multi-Spectral Camera) Operational Parameters

  • Yong, Sang-Soon;Kong, Jong-Pil;Heo, Haeng-Pal;Kim, Young-Sun
    • Korean Journal of Remote Sensing
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    • v.18 no.1
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    • pp.53-59
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    • 2002
  • The MSC is a payload on the KOMPSAT-2 satellite to perform the earth remote sensing. The instrument images the earth using a push-broom motion with a swath width of 15 km and a GSD(Ground Sample Distance) of 1 m over the entire FOV(Field Of View) at altitude 685 km. The instrument is designed to haute an on-orbit operation duty cycle of 20% over the mission lifetime of 3 years with the functions of programmable gain/offset and on-board image data compression/storage. The MSC instrument has one channel for panchromatic imaging and four channel for multi-spectral imaging covering the spectral range from 450nm to 900nm using TDI(Time Belayed Integration) CCD(Charge Coupled Device) FPA(Focal Plane Assembly). The MSC hardware consists of three subsystem, EOS(Electro Optic camera Subsystem), PMU(Payload Management Unit) and PDTS(Payload Data Transmission Subsystem) and each subsystems are currently under development and will be integrated and verified through functional and space environment tests. Final verified MSC will be delivered to spacecraft bus for AIT(Assembly, Integration and Test) and then COMSAT-2 satellite will be launched after verification process through IST(Integrated Satellite Test). In this paper, the introduction of MSC, the configuration of MSC electronics including electrical interlace and design of CEU(Camera Electronic Unit) in EOS are described. MSC Operation parameters induced from the operation concept are discussed and analyzed to find the influence of system for on-orbit operation in future.

An Adaptive Transmission Power Control Algorithm for Wearable Healthcare Systems Based on Variations in the Body Conditions

  • Lee, Woosik;Kim, Namgi;Lee, Byoung-Dai
    • Journal of Information Processing Systems
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    • v.15 no.3
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    • pp.593-603
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    • 2019
  • In wearable healthcare systems, sensor devices can be deployed in places around the human body such as the stomach, back, arms, and legs. The sensors use tiny batteries, which have limited resources, and old sensor batteries must be replaced with new batteries. It is difficult to deploy sensor devices directly into the human body. Therefore, instead of replacing sensor batteries, increasing the lifetime of sensor devices is more efficient. A transmission power control (TPC) algorithm is a representative technique to increase the lifetime of sensor devices. Sensor devices using a TPC algorithm control their transmission power level (TPL) to reduce battery energy consumption. The TPC algorithm operates on a closed-loop mechanism that consists of two parts, such as sensor and sink devices. Most previous research considered only the sink part of devices in the closed-loop. If we consider both the sensor and sink parts of a closed-loop mechanism, sensor devices reduce energy consumption more than previous systems that only consider the sensor part. In this paper, we propose a new approach to consider both the sensor and sink as part of a closed-loop mechanism for efficient energy management of sensor devices. Our proposed approach judges the current channel condition based on the values of various body sensors. If the current channel is not optimal, sensor devices maintain their current TPL without communication to save the sensor's batteries. Otherwise, they find an optimal TPL. To compare performance with other TPC algorithms, we implemented a TPC algorithm and embedded it into sensor devices. Our experimental results show that our new algorithm is better than other TPC algorithms, such as linear, binary, hybrid, and ATPC.

A study on the crowdfunding strategies of start-up businesses -focusing on the impact of perceived justice on customer satisfaction and loyalty- (스타트업 기업들의 크라우드 펀딩 전략에 관한 연구 -지각된 공정성이 고객의 만족도와 충성도에 미치는 영향을 중심으로-)

  • Kim, Seung-Hwan;Lee, Sang-Hoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.12
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    • pp.515-522
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    • 2018
  • Current signs of a downturn in South Korea's economy include the sharp drop in consumption. Considering internal and external complications such as the raise in minimum wage and fierce global competition, people's taste and purpose of consumption is shifting as well. Under such circumstances, crowdfunding provides a new investment and distribution channel for businesses in their initial stages. Crowdfunding can serve as a key driver of growth in early stages of business operations and lead to growth in consumption as a new distribution channel. This study explores how customers perceive the process of reward crowdfunding, especially when it comes to fairness in procedure, interaction, and distribution. In addition, we further seek how perceived fairness affects customer satisfaction and loyalty in the industry.

Implementation and Evaluation of Secure VoIP Conference System (DTLS 기반의 안전한 VoIP 컨퍼런스 시스템 구현 및 평가)

  • Kang, Seong-Ku;Kim, Kyou-Young;Kim, Joong-Man;Won, Yoo-Jae;Ryou, Jae-Cheol
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.19 no.5
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    • pp.45-57
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    • 2009
  • In this paper, we implemented the conference system based on DTLS for saving securely the VoIP, which is served sprightly in the latest, securely and tested (and also analyzed) the system. As VoIP technology development, demand of conference system is increased and the related technologies are growed. But Security protocol to protect conference service is getting late than conference technology. In this paper, we studied based on DTLS protocol that can provide function of signaling, channel security, media channel security and application of group key and apply to VoIP conference system based UDP unchanged. In this paper, we searched suggested security protocols based on DTLS can apply to conference system and implement and apply the protocol to conference system. And we tested (and also alayzed) overhead of encryption and key management mechanism.

Secure Contents Access Control System in IPTV Flexible-PPC Model (IPTV Flexible-PPC 환경에서의 안전한 콘텐츠 접근 제어 시스템)

  • Kang, Yong-Goo;Lim, Ji-Hwan;Oh, Hee-Kuck
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.21 no.1
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    • pp.93-104
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    • 2011
  • A conditional access system is an essential element in IPTV services enabling service providers to allow authorized access to their services only to paid subscribers. Currently, there are two types of IPTV service models, namely PPC (pay-per-channel) and PPV (pay-per-view). However, a more desirable model would be the flexible PPC model, in which subscribers are free to choose any combination of preferred channels and add/remove channels independently. In this paper, we first point out that a previously proposed key management scheme for F-PPC is not secure. We then propose a new conditional access system using 4-level key hierarchy to realize secure F-PPC services. Compared to existing schemes, the proposed system is very efficient, just requiring O(1) communication for key update.

Texture-Spatial Separation based Feature Distillation Network for Single Image Super Resolution (단일 영상 초해상도를 위한 질감-공간 분리 기반의 특징 분류 네트워크)

  • Hyun Ho Han
    • Journal of Digital Policy
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    • v.2 no.3
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    • pp.1-7
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    • 2023
  • In this paper, I proposes a method for performing single image super resolution by separating texture-spatial domains and then classifying features based on detailed information. In CNN (Convolutional Neural Network) based super resolution, the complex procedures and generation of redundant feature information in feature estimation process for enhancing details can lead to quality degradation in super resolution. The proposed method reduced procedural complexity and minimizes generation of redundant feature information by splitting input image into two channels: texture and spatial. In texture channel, a feature refinement process with step-wise skip connections is applied for detail restoration, while in spatial channel, a method is introduced to preserve the structural features of the image. Experimental results using proposed method demonstrate improved performance in terms of PSNR and SSIM evaluations compared to existing super resolution methods, confirmed the enhancement in quality.

Compensation Characteristics Depending on Extinction Ratio of RZ Pulse in Dispersion-managed Link Combined with MSSI (MSSI와 결합된 분산 제어 링크에서 RZ 펄스의 소광비에 따른 보상 특성)

  • Seong-Real Lee
    • Journal of Advanced Navigation Technology
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    • v.28 no.1
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    • pp.123-128
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    • 2024
  • When mid-span spectral inversion (MSSI), which inverts the propagated wave into phase-conjugated wave in the middle of the entire transmission distance, is combined with dispersion-managed link, it is very effective in compensating for the wavelength division multiplexed (WDM) signal distortion due to chromatic dispersion and nonlinear effects. In this MSSI combined dispersion-managed link, the shape of the dispersion map, channel data rate, channel wavelength and wavelength spacing, etc. affect the compensation and, consequently, determine the transmission distance and capacity of the WDM signal. In this paper, the compensation according to the extinction ratio of the return-to-zero (RZ) pulse that constitutes the WDM signal in the MSSI combined distributed control link was numerically analyzed. As a result of the simulation, it was conformed that the extinction ratio to obtain the best compensation should be determined depending on the shape of the dispersion map and the size of the residual dispersion per span, which determines the specific shape of the dispersion map. These results show a significant difference from the results in a general optical transmission system, where as the extinction ratio increases, the power difference between the '1' and '0' signals increases, thereby improving reception performance.

MSSI System with Dispersion-Managed Link Designed with Geometric-Schemed Dispersion Map (기하학적 구조의 분산 맵으로 설계된 분산 제어 링크를 갖는 MSSI 시스템)

  • Seong-Real Lee
    • Journal of Advanced Navigation Technology
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    • v.28 no.5
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    • pp.732-737
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    • 2024
  • We systematically studied the chromatic dispersion and nonlinear distortion compensation characteristics of 24-channel × 40 Gb/s wavelength division multiplexed (WDM) signal in a mid-span spectral inversion (MSSI) system with dispersion-managed link. WDM signals are transmitted over dispersion-managed link consisting of an 80 km × 48 fiber span including erbium-doped fiber amplifier (EDFA). The dispersion map applied to this dispersion-managed link has trapezoidal shape with various structures. The trapezoid-shaped dispersion map examined in this paper are designed with configuration in which the cumulative dispersion profile has positive or negative value in each section before and after the optical phase conjugator. Through simulation, it was confirmed that the proposed trapezoid-shaped dispersion map is effective in compensating for distorted WDM channel signals when the dispersion map is configured with the small RDPS (residual dispersion per span).

Quality Assessment of Hypertension Management of Office-based Physicians in Korea (우리 나라 개원의 고혈압 관리의 질 평가)

  • Cho, Hong-Jun;Lee, Sang-Il
    • Quality Improvement in Health Care
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    • v.4 no.1
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    • pp.36-49
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    • 1997
  • Background : Hypertension is one of the most important risk factors of the cerebrovascular accident and coronary artery disease which are the major causes of mortality in Korea. In Korea, the quality of care provided by office-based physicians has not been evaluated formally. The purpose of this study is to assess the quality of hypertension management of office-based physicians. Method : Self-administered questionnaires were mailed to the office-based physicians with the speciality of internal medicine, general surgery, family medicine, and general practitioners. Among 2,045 physicians, 981 doctors(48.0%) replied the questionnaires. Contents of questionnaires were based on the recommendation from the JNC-V report(the Fifth Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure), and included the criteria of diagnosis, treatment, follow-up interval, and other characteristics of physicians(age, sex, type of speciality, and location of practice). Results : Eighty four percent of the office-based physicians made diagnosis of hypertension with less than 3 times of blood pressure measurements. The performance rate of required examination for hypertensives was very low in most items. Rate of fundoscopic examination is the lowest one among them(5.9%). The performance rate of laboratory examination was also low in most items. Internists tended to order more frequent laboratory examinations than any other type of physicians. Only 11.4% of the physicians did appropriate treatments for the mild hypertension case. The antihypertensives selected by the physicians as a first line drug were in the order of beta blocker(26.4%), calcium channel blocker(23.4%), diuretics(23.1%), ACE inhibitors(14.3%). The visit interval for established hypertensives was very short. Proportion of physicians with follow-up interval longer than 4 weeks was only 4.3%. Conclusions : The overall quality of hypertension management of office-based physicians in Korea is very problematic in many aspects. So further investigations to find out the reasons of low quality arid quality of care should be initiated.

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