This paper analyzed the qualitative evaluation indicators of the SYSTEM sector of the LINC program, which aimed at strengthening ability of regional universities through the activities of industry-academia cooperation (IAC). By using interview data and the program reports of universities, this research explored the problems of the indicators and suggested improvement measures which could lead to performance creativity. According to research results, in university system reform for activating IAC, some improvements are required as follows: limiting excessive expansion of IAC-friendly faculty evaluation; and evaluating soft aspects in the reform of academic affairs. In relation to strengthening of ability of the IAC organization, the indicators need to be amended as follows: enhancing the role of channel of IAC Foundation; strengthening the function of planning team of the IAC Foundation; and inducing development of own model of universities for IAC. As regards expansion of IAC infrastructure, it is necessary to enlarge the manpower who can develop programs of the support center in the foundation and to secure of operators for effective operation of joint-using equipments. Therefore, the indicators are required to be upgraded, considering these improvement direction.
In this study, we studied whether hydrogen sulfide ($H_2S$) has an effect on the pacemaker activity of interstitial cells of Cajal (ICC), in the small intestine of mice. The actions of $H_2S$ on pacemaker activity were investigated using whole-cell patch-clamp technique, intracellular $Ca^{2+}$ analysis at $30^{\circ}C$ and RT-PCR in cultured mouse intestinal ICC. Exogenously applied sodium hydrogen sulfide (NaHS), a donor of hydrogen sulfide, caused a slight tonic inward current on pacemaker activity in ICC at low concentrations (50 and $100{\mu}m$), but at high concentration ($500{\mu}m$ and 1 mM) it seemed to cause light tonic inward currents and then inhibited pacemaker amplitude and pacemaker frequency, and also an increase in the resting currents in the outward direction. Glibenclamide or other potassium channel blockers (TEA, $BaCl_2$, apamin or 4-aminopydirine) did not have an effect on NaHS-induced action in ICC. The exogenous application of carbonilcyanide p-triflouromethoxyphenylhydrazone (FCCP) and thapsigargin also inhibited the pacemaker activity of ICC as NaHS. Also, we found NaHS inhibited the spontaneous intracellular $Ca^{2+}$ ($[Ca^{2+}]_i$) oscillations in cultured ICC. In doing an RT-PCR experiment, we found that ICC enriched population lacked mRNA for both CSE and CBS, but was prominently detected in unsorted muscle. In conclusion, $H_2S$ inhibited the pacemaker activity of ICC by modulating intracellular $Ca^{2+}$. These results can serve as evidence of the physiological action of $H_2S$ as acting on the ICC in gastrointestinal (GI) motility.
Journal of Korean Academy of Nursing Administration
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v.5
no.3
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pp.445-462
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1999
The purpose of this study is to provide some basic data for the direction of nursing education and practice to prevent nursing malpractice as investgating perception of the nurse on the nursing malpractice and its case. Data were collected from 450 nurse working in four general hospitals which were located in Chonbuk province from November 9 to 21, 1998 through questionnare. The structured instruments developed by the reseacher were used for collecting data. The Results were as follows: 1) As for the cognition of the nursing malpractice case, the transfusion accident was 37.3%, the side-effects of KCL injection(19.3%), hymen rupture by uterus cancer test, the side-effects of aminophyllin injections on dyspnea patient and the others were 10% below. 2) With regard to the channel of the perception of the nursing malpractice case, mass-communication was taken first and followed through by neighbors, In-service education, school education, continuing education 3) As for the direct${\cdot}$indirect experience of the nursing malpractice case, transfusion accident was 51.3%, the fall of NPO patient after an operation 40.1%, the side-effect of KCL injection 32.5%, suicide of the psychiatric patient 32.5%, and the others were 30% below. 4) The possibility of nursing malpractice case was an average 2.57(${\pm}$0.91) and the highest was the fall of the NPO patient after an operation. 5) The perception on the responsibility of the nursing malpractice in its case was indicated as a joint-fault in ten nursing malpractice instances. As compared to the real decision, nurse's perception of the responsibility in the fall of the NPO patient after an operation, the side-effect of KCL injection, the tracheal edema of the patient who had a thyroid operation, the suicide of psychiatric patient, the hymen rupture by uterus cancer test accorded real decisions. But the other cases were different from the real decisions. These cases were perceived as ones of joint fault even in cases determined as Dr's single fault cases or those in which both doctor and nurse were declared free of fault. 6) Knowledge levels of the nursing malpractice, school education and In-service education were perceived as low but anxiety levels of the malpractice were high. 7) With regard to the countmeasure of the hospital after nursing malpractice, the rate answered as "the practice settled the accident temporarily and forced the person in charge to be punished" was highest. In conclusion, the level of the cognition of the clinical nurse on nursing malpractice cases was low. As nurses' perception on the responsibility of the nursing malpractice case was compared to the real decision, there was a difference in five cases out of the ten cases.
The objective of this study is to suggest new drawing methods of isochrones using GIS. For this purpose the Unit Hydrograph (UH) of studied watershed for instantaneous rainfall suggested by Clark have been determined by routing the time-area curve through a single linear reservoir. To evaluate constructing methods of isochrones three methods has been examined; Channel Profile and Clark-kict method; Laurenson method; Average velocity method of S.C.S. Also, these methods have been recomposed by GIS in this study. To apply first method, spatial modeling, the vector based on the stream network and Route_System measuring a distance between points has been used. A raster based on the flow direction grid from burn DEM and the slope grid from original DEM has been applied for the second method. The third method has been applied by a raster based on the landuse grid and a velocity function expressed by slope. Results by these three methods have been evaluated with observed hydrograph, and the method using average velocity method of S.C.S shows more reasonable results comparatively.
In joint portions of the levee and the barrier, complex 3-dimensional flow was generated and collapse of revetment occurred frequently. For these reasons, it is necessary to install the joint revetment with greater stability as compared with the general revetment at the joint portions. However, design criteria for joint revetment was not presented in River Design Criteria (KWRA, 2009). Therefore it is necessary to research for engineering design of the joint revetment. In this study, hydraulic experiments were performed under various flow conditions in order to realize the collapse conditions of riprap and carried out in 20.0 m straight open channel with one side levee and the width was 4.0 m. The diameter of riprap covered around joint revetment was 0.03 m and the inlet discharges were $0.5{\sim}0.8m^3/s$. The numerical simulations were performed under same conditions with experiment. as results of this numerical simulations, the influence range was confirmed from the distribution of flow characteristics and shear stress. As a result, the riprap diameter of the joint revetment was calculated from 4.1 to 6.9 times greater than that of general revetment. As the inlet discharge was large, the range of vulnerable area was developed long in the downstream direction despite of same withdrawal velocity of riprap. Through this study, the methods of calculating the riprap diameter and influence range were proposed according to hydraulic characteristics of flow around joint revetment. At a later study, if additional experiments about effect of flood plane and various types of barrier is applied, it is expected that rational design method with stability of joint revetment can be proposed.
Kim, Sang-Ho;Lyu, Seung-Jun;Han, Won-Ju;Kim, Mo-Kyung;Kim, Tae-Heon;Kang, Hyung-Won;Lyu, Yeoung-Su
Journal of Oriental Neuropsychiatry
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v.16
no.2
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pp.13-24
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2005
Background and Objectives : Acupuncture as a therapeutic intervention is widely used for the treatment of many functional disorders such as substance abuse and mental dysfunction. Clinical trials are currently underway to determine the effectiveness of acupuncture in the treatment of drug addiction. Yet, there are still many unanswered questions about the basic mechanism of acupuncture. Studies have shown that both the psychomotor stimulant effects and rewarding properties of addictive drugs, including morphine, are sensitized by repeated drug administration and raised the possibility that both of these effects may be linked to the same or closely overlapping the mesolimbic dopamine systems. Neiguan (PC6) point on the pericardium channel which is associated with the brain and its mental function, has been used to treat mental, psychosomatic disorders and gastroenterological disorders. The present study was designed to investigate the effect of acupuncture on repeated morphine-induced changes in extracellular dopamine levels using in vivo microdialysis and to measure the effect of acupuncture on Fos-like immunoreactivity. Methods : Male Sprague-Dawley rats were treated twice a day for three days with increasing doses of morphine (10, 20 and 40 mg/kg, s.c.) or with saline. After 15 days of withdrawal, rats were challenged with morphine hydrochloride (5 mg/kg, s.c.). Acupuncture was applied at bilateral Neiguan (PC6) points for 1 min after the morphine challenge. Results showed that acupuncture at the specific acupoint PC6, but not at control points (tail and HE8) significantly decreased Fos-like immunoreactivity induced by a systemic morphine challenge or a single s.c. morphine injection in the morphine-repeated animals. Results and Conclusions : These results suggest that reduction in sensitization may be one mechanism whereby acupuncture alleviates morphine craving in addicts. Moreover, in a more general sense these results suggest that acupuncture can be used as a therapeutic intervention for correcting reversible malfunction of the body by direction of brain pathway and thus acupuncture can contribute to the biochemical balance in the central nervous system by regulating neurotransmitters.
Proceedings of the Korean Institute of Navigation and Port Research Conference
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2007.12a
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pp.141-142
/
2007
In recent years, the rate of mean sea level rise is increasing rapidly from the phenomena of global warming, together with the increasing trend of the storm scale. The issue of sea level rise is multifaceted and produces a range of environmental problems. Especially, high tides and the tidal currents become higher, and wave base increases, so the energy received at the coastal boundary may increase. This brings that many coastal environments go into disequilibrium, such as damages to the structures, erosion, and deposition Similarly it was known that the problems of nearshore processes and damage of berth and counter facilities during storm period had appeared at the small fishery port. Here we try to analyze the impact of the rearrangement of counter facilities and berth layout adopted for tranquility of its'inner harbor. Because this harbor is being connected to channel and open sea, the rearrangement of the structures might affect to the current speed and direction and wave height, so do to the sea bottom undulation. Therefore, we made model test for the several layouts of the berth and breakwater in this area.
Kim, Sung-Joong;Jung, Do-Joon;Kang, Joon-Gu;Yeo, Hong-Koo;Kim, Jong-Tae
Journal of the Korea Academia-Industrial cooperation Society
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v.17
no.3
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pp.31-41
/
2016
Damage to structures, such as bridge piers, are increasing rapidly due to the debris moving along rivers at the time of flooding. Therefore, the debris fin, debris deflector and debris sweeper, which are debris reduction systems, were produced in this study and an accumulation experiment was carried out on the experimental channel according to the existence of the reduction system. The debris fin is the reduction system that creates parallel flow on debris accumulated on the bridge to pass through the bridge, which was produced using wood. In addition, the debris deflector was produced using steel pipes and it has the type of detouring the direction of debris. The debris sweeper passes the debris using the magnetic force rotation of a screw-shaped cylindrical structure by water flow and it was produced using acrylic material. The experiment was carried out by analyzing the level of accumulation according to the hardness and dropping method of the debris and comparing the accumulation rate of reduction systems, and the experiment was carried out 5 times. According to the experimental results, there was a difference in the accumulation rate according to the type of reduction system and the shape of debris, and it often depended significantly on the initial shape of debris accumulation. The direct debris reduction effect on the bridge was higher in the order of the debris deflector, debris sweeper and debris fin, but in case of the debris deflector, damage, such as stream turbulence, changes in water level and river bed, and the loss of deflector can occur due to debris accumulated directly on the debris deflector. Therefore, it is necessary to design the debris deflector considering these issues.
Lee, Han Rim;Min, Chul Hee;Park, Jong Hoon;Kim, Seong Hoon;Kim, Chan Hyeong
Progress in Medical Physics
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v.23
no.3
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pp.162-168
/
2012
In proton therapy, in vivo dose verification is one of the most important parts to fully utilize characteristics of proton dose distribution concentrating high dose with steep gradient and guarantee the patient safety. Currently, in order to image the proton dose distribution, a prompt gamma distribution detection system, which consists of an array of multiple CsI(Tl) scintillation detectors in the vertical direction, a collimator, and a multi-channel DAQ system is under development. In the present study, the optimal design of prompt gamma distribution detection system was studied by Monte Carlo simulations using the MCNPX code. For effective measurement of high-energy prompt gammas with enough imaging resolution, the dimensions of the CsI(Tl) scintillator was determined to be $6{\times}6{\times}50mm^3$. In order to maximize the detection efficiency for prompt gammas while minimizing the contribution of background gammas generated by neutron captures, the hole size and the length of the collimator were optimized as $6{\times}6mm^2$ and 150 mm, respectively. Finally, the performance of the detection system optimized in the present study was predicted by Monte Carlo simulations for a 150 MeV proton beam. Our result shows that the detection system in the optimal dimensions can effectively measure the 2D prompt gamma distribution and determine the beam range within 1 mm errors for 150 MeV proton beam.
Smartphones provide users with environment for communication and sharing information and at the same time play an important role of mobile technology and mobile art development. Smartphone technology-related researches are being accelerated especially with the advent of mobile Augmented Reality(AR) age, but the studies on user participation that is essential for AR content industry were insufficient. In that regard, the assistance from mobile art area that has already developed these characteristics is essential. Thus, this article is to classify mobile art that has not been studied a lot domestically into feature phone usage and smartphone usage and to analyze each example case with the three most used methods. The usage of feature phones which use the sound and images of mobile devices can be divided into three: installation and performing methods, single channel video art method and five senses communication method. On the other hand, the usage of smartphones that use sensors, cameras, GPS and AR can be divided into location-based AR, marker-based AR and markerless AR. Also, as a result of examining mobile AR content utilization technology by industries, combined methods are utilized; tourism and game-related industries use location-based AR, education and medicine-related industries use marker-based AR, and shopping-related industries use markerless AR. The development of AR content industry is expected to be accelerated with mobile art that makes use of combined technology method and constant communication method through active participation of users. The future development direction of mobile AR industry is predicted to have minimized HMD, integration of hologram technology and artificial intelligence and make the most of big data and social network so that we could overcome the technological limitation of AR.
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