• Journal of Haehwa Medicine
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• v.28 no.2
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• pp.1-11
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• 2019

Objective: The aim of this study is to analyze the previously published research articles related to puffer fish toxin focusing on tumor. Method: Literatures were searched in PubMed database, published since 2000, using the keyword; Puffer fish, Fugu and tetrodotoxin (TTX) with cancer or tumor. Research papers were classified by year, country, study model, used material, kind of tumor and study subject. Finally, a total of 41 studies were analyzed in this study. Results: From 2000 to 2018, the most abundant papers were published in 2009 (6 studies) and almost half of the papers were studied in United Kingdom (20 studies). The 39 studies used TTX purified from puffer fish while 2 studies used crude extract of skin and gonad of puffer fish. The most used target cell line was prostate cancer (15 studies), and the next was breast cancer (14 studies). The study methods were classified into 4 clinical studies, 2 animal studies and 35 cell-based studies. Conclusions: Our results show that the overview of cancer-related studies using puffer fish poison. This information would be helpful for the puffer fish-derived drug researches in the future.

• Journal of the Korean Society for Precision Engineering
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• v.33 no.7
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• pp.595-600
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• 2016

An orbital grinding system uses a special motion to machine crankshafts in ships. When a crankshaft is operated, eccentric pins rotate and a grinding wheel moves in order to grind the pins. Thermal error caused by heat generated in the grinding process decreases the quality of the final product. In this study, the thermal error of an orbital grinding system caused by heat generation was investigated in order to predict the extent of thermal error that can occur during the grinding process. Since the machine position changes during orbital grinding, the pin part is divided into 30 degree intervals and heat is generated. Total thermal error was measured by summing the thermal errors associated with the pin and the grinding wheel. Total thermal error was found to reach a maximum at 60 degrees and a minimum at 210 degrees because of the shape of the crankshaft.

• Asia pacific journal of information systems
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• v.11 no.1
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• pp.1-24
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• 2001

This paper is aimed at proposing a new inference mechanism for B-to-B electronic commerce decision-makings, named IMITAO(Integer Matrix-driven Inference based on Transformed And-Or graph) which is based on integer matrix operation to speed up the inference. During the B-to-B electronic commerce, many kinds of negotiations are needed for mutually satisfactory decision-makings. During such negotiations, several factors including subjective and objective constraints should be considered so as to reach satisfactory decisions. In this respect, we suggest first a Transformed AND-OR Graph(TAOG) which each firm's conditions or judgement are incorporated into, and then we propose a high-speedy inference mechanism named IMITAO which basically depends on TAOG. Firms engaged in B-to-B negotiations on the Internet can get an appropriate decision support from using IMITAO for their negotiation simulations. The proposed IMITAO inference mechanism is characterized by its fast inference because its main inference procedures are based on integer matrix operation. A real-world example for B-to-B negotiations was used to prove the validity of our proposed TAOG and IMITAO approach. Experimental results showed that our approach was very useful in performing the B-to-B electronic commerce decision-makings considering a wide variety of either subjective or objective constraints.

• Proceedings of the Korea Water Resources Association Conference
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• 2006.05a
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• pp.1621-1625
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• 2006

하천은 여러 하천의 연결망으로 구성되어 있으며, 연결부는 절점으로 이루어져 있고, 이 절점은 하천이 합류하는 곳으로서 하천의 시스템을 구성하는 가장 중요한 요소이다. 최근에 친자연 하천 복원 등의 많은 사업을 하고 있음에도 불구하고 이에 대한 검토가 거의 이루어지지 않고 있으며, 이를 검토하고 이해하는 것이 하천을 복원하고 관리하는데 매우 중요하다. 본 연구는 본류와 지류의 하상경사 및 하상고가 다르고, 유사 유입조건이 다른 비평형 유입조건을 갖고 있으며, 하폭이 넓고 수심이 상대적으로 얕은 합류부에서 흐름 및 하상변동에 관하여 수치모의를 수행하여 그 특성을 파악하는데 그 목적이 있다. 적용 대상지역은 금강과 미호천의 합류부로서, 흐름 특성 및 하상변동을 모의하기 위하여 RMA-2와 SED2D를 이용하였다. 유량의 증가에 따라 흐름에 대한 유속이 증가하며, 전단층의 길이가 증가하고, 합류부의 우안의 정체수역에서 발생하는 와(vortex)의 크기도 증가하였다. 부유사의 농도는 실제 상황에 맞도록 비평형 유입조건을 사용하였으며, 미호천에서 유입되는 유사의 농도에 영향을 받아, 합류직후에도 유사의 농도가 높으며, 전단층을 경계로 하여 농도 띠가 하류로 유지되었으며, 합류 후에는 우안에서는 하상이 상승되었다.

• Proceedings of the Korea Water Resources Association Conference
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• 2006.05a
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• pp.1551-1555
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• 2006

효율적인 댐 운영 및 관리를 위하여 퇴사유입으로 인한 저수용량의 감소에 대한 정량적인 분석이 필수적이다. 본 연구의 대상지인 소양호는 소양강댐이 준공된 1973년을 기준으로 매 10년마다 세부측량을 통한 퇴사량 조사가 실시되고 있다. 기존의 조사에서는 장기적인 퇴사량 예측을 위해 U.S.B.R의 경험적 면적감소법과 90년대 초반부터는 1차원 모형인 HEC-6가 적용되어 왔다. 그러나 기존의 방법은 저수지 내 퇴사의 횡방향 분포는 고려할 수 없다는 단점이 있다. 이를 보완하기 위해 저수지 횡단방향으로의 퇴적과 세굴을 모의할 수 있는 2차원 이상의 모형이 적용되어야 한다. 본 연구에서는 소양호의 장래퇴사분포를 모의하였다. 현재 실무에서 주로 이용되고 있는 HEC-6 모형과 2차원 수치모형인 HSCTM2D(Hydordynamics, Sediment and Contaminant Transport Model)모형 및 SMS-SED2D 모형을 비교한 후 SMS-SED2D 모형을 소양강댐 유역에 적용하였다. 또한 모형의 매개변수 보정을 위하여 퇴사량 조사용역으로 수행된 1983년과 2005년의 실측횡단자료를 이용하였으며, 향후 소양강댐의 관리를 위한 기초자료로의 활용을 위하여 댐 축조후 50년, 100년후의 저수지내 퇴사분포를 모의하였다.

• Tuberculosis and Respiratory Diseases
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• v.69 no.4
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• pp.298-302
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• 2010

Scedosporium apiospermum, the anamorph of Pseudallescheria boydii, is a ubiquitous saprophytic fungus. S. apiospermum can cause life-threatening infections usually in immunocompromised patients or after near-drowning incidents. Here, we report the first case of disseminated infection caused by S. apiospermum after near-drowning in Korea. A 44-year-old healthy man developed aspiration pneumonia, followed by multiple brain abscesses, and endopthalmitis, after a near-drowning incident in a septic tank. S. apiospermum infection was diagnosed on the 33rd day after the incident had occurred. The patient died from the progressive renal failure 255 days after incident, although he had been treated with voriconazole.

• Journal of the Korean Solar Energy Society
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• v.21 no.4
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• pp.63-71
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• 2001

This work has been carried out to find the ideal operating conditions for solar vacuum tube collectors which are widely used at present. Various types of solar collectors including a flat plate one were experimentally tested and examined to determine their thermal efficiencies and operating characteristics. Generally, solar vacuum tubes can be classified into two groups according to their design features. Of these, one is characterized by the insertion of a metallic device(such as a finned heat pipe) in an evacuated glass tube for the collection and transportation of solar energy. The other utilizes double glass tubes where the smaller one is contained inside the bigger one and soldered to each other after the small gap between them is evacuated. Both of these solar collectors are designed to minimize convection heat losses by removing the air which is in direct contact with the absorber surface. The performance of the former type can be readily analyzed by applying the relevant correlations developed for flat plate solar collectors. This has been demonstrated in the present study for the case of a solar collector where a heat pipe is inserted in an evacuated tube.

• Journal of Electrical Engineering and Technology
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• v.7 no.5
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• pp.653-658
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• 2012

Load modeling has a significant influence on power system analysis and control. In recent years, measurement-based load modeling has been widely practiced. In the load modeling algorithm, the model structure is determined and the parameters of the established model are estimated. For parameter estimation, least-squares optimization method is applied. The model parameters are estimated so that the error between the measured values and the predicted values is to be minimized. By introducing sliding window concept, on-line load modeling method can be performed which reflects the dynamic behaviors of loads in real-time. For the purpose of data acquisition, the measurement system including PMU is implemented in university level. In this paper, case studies are performed using real PMU data from Korea Univ. and Seoul National University of Science and Technology. The performances of modeling real and reactive power behaviors using exponential and ZIP load model are evaluated.

• Proceedings of the KIPE Conference
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• 2011.07a
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• pp.179-180
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• 2011

This paper focuses on the Current-Voltage concurrent control method devoted to the multiple LED (light-emitting diode) string driver. Isolated DC to DC converter with cascaded chopping switch is proposed for smart lighting system such as light with sensor or back light unit of display, which need to control the current of parallel connected multiple LED stings and regulate DC voltage for micro controller for brightness control. The proposed circuit regulates the current of parallel connected multiple LED strings and additional DC voltage output simultaneously. To verify the performance, experimental results are presented based on the prototype board. 5V, 1A voltage mode electric load and two LED strings with different forward voltages are used for output loads. 23W output power is achieved and measured efficiency is in the range of 85%-87%

• Journal of Preventive Medicine and Public Health
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• v.23 no.1 s.29
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• pp.65-76
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• 1990

Hospitals are experiencing an increasing amount of financial difficulty due to government control of hospital rates since national health insurance has been implemented. The decision support system (DSS) was developed to provide cost and revenue information for the services rendered by each department in an effort to reduce costs. This information may be used to identify the causes of financial loss if cost exceeds revenue and to conduct variance analysis or portfolio analysis to improve financial situation of hospitals. The DSS was developed using a micro-mainframe interface approach where the mainframe computer collects and summarizes daily cost and revenue data and the micro computer computes the cost for each department. The significances of this paper are to determine the cost allocation basis and methods which are suitable to Korean situation and to apply DSS technology to the cost analysis.