• 제목/요약/키워드: Chang-rae Lee

검색결과 411건 처리시간 0.035초

Analysis of Flood Reduction Effect of Washland using Hydraulic Experiment (수리실험을 이용한 강변저류지의 홍수조절효과 분석)

  • Kim, Duck-Gil;Lee, Lim-Yeol;Lee, Chang-Won;Kang, Na-Rae;Lee, Jong-So;Kim, Hung-Soo
    • Journal of Wetlands Research
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    • 제13권2호
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    • pp.307-317
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    • 2011
  • Recently, we have a growing interest in the washland construction for the function of flood control. Therefore this study analyzed flood reduction effect of washland using hydraulic experiment. We used open-channel unit for flood reduction effect of washland. And we used side weir to lateral structure. The result of hydraulic experiment showed a decrease of the average velocity and discharge according to the installation location of side weir. Also, we compared the results of HEC-RAS model and hydraulic experiment for the review of the result of hydraulic experiment. As the result, hydraulic experiment and HEC-RAS model have showed the similar results.

Inhibitory Effects of Wogonin Mixed with Hydrogel on Osteoclast Differentiation (우고닌-하이드로젤 지지체의 파골세포 분화 억제 효과)

  • Yang, Na-Rae;Lee, Jin-Moo;Lee, Chang-Hoon;Jang, Jun-Bock;Lee, Kyung-Sub
    • The Journal of Korean Obstetrics and Gynecology
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    • 제24권4호
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    • pp.1-9
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    • 2011
  • Purpose: Wogonin is an active component isolated from scutellariae radix. This study was conducted to evaluate the inhibitory effect of wogonin mixed with hydrogel on osteoclast differentiation. Methods: It was performed to estimate cytotoxicity of Wogonin alginate hydrogel disk(WHD) in BMMs stimulated with RANKL, M-CSF. ROS synthesis and actin ring formation were analysed to observe the effect of WHD. Results: WHD has no cytotoxicity at the concentration of 0.1 ${\mu}g/ml$ or lower. 0.1 ${\mu}g/ml$, 1 ${\mu}g/ml$ WHD restrained the synthesis of ROS and 0.1 ${\mu}g/ml$, 1 ${\mu}g/ml$ WHD restrained the formation of actin ring. Conclusions: WHD has the inhibitory effect of osteoclast differentiation and bone resorption. Further studies are needed to treat osteoporosis by herbal medicine.

Study on Synergistic Anti-tumor Effect of Combination with Adriamycin and Palginhonhapwhajucwhan (팔진탕합화적환(八珍湯合化積丸)과 Adriamycin의 병용처리시 나타나는 synergistic 항종양(抗腫瘍) 효과(效果)에 관(關)한 작용기전 연구(硏究))

  • Moon, Gu;Moon, Seok-Jae;Won, Jin-Hee;Cho, Jung-Yun;Park, Sang-Gu;Song, Bong-Gil;Park, Rae-Gil;Lee, Byung-Gu
    • The Journal of Internal Korean Medicine
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    • 제21권3호
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    • pp.443-452
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    • 2000
  • Objective : This study was designed to evaluate the synergistic effect on cytotoxicity of combination with adriamycin and Palginhonhapwhajucwhan, a traditional prescription for cancer treatment in oriental medicine, in Chang, HL-60, Hep-3B and Alexander cells. Methods : We observed cell viability in Chang, HL-60, Hep-3B, and Alexander cells by crystal violet staining. Those cells were treated with various concentrations of adriamycin alone, Palginhonhapwhajucwhan alone and combination of two medications for 10 hr. On condition of $0.5{\mu}l/ml$ adriamycin alone, $15.6{\mu}l/ml$ Paljintanghapwhajucwhan alone and combination of two medications, at first, we observed colony forming of Chang and HL-60 cells. Second, we observed DNA fragmentation by agarose electrophoresis in Chang, HL-60, Hep-38 and Alexander cells. Third, we measured the catalytic activation of caspase-1, 2, 3, 6, 8, and 9 protease in Chang cells and caspase-3 protease in Chang, HL-60, Hep-3B and Alexander cells by using fluorogenic substrate. Finally, we isolated mRNA of Fas in Chang, HL-60, Hep-38 and Alexander cells and observed that Fas gene was amplified by RT-PCR Results : 1. The combination of adriamycin and Palginhonhapwhajucwhan synergistically augmented the cytotoxicity of Chang and HL-60 cells whereas did not in Hep-38 and Alexander cells. 2. Cotreatment of two drugs also markedly inhibited the colony forming ability both in Chang and HL-60 cells. 3. The cytotoxicity of these medicatons was revealed as apoptosis characterized by high molecular wight DNA fragmentaton. 4. The apoptotic cytotoxicity was mediated by activation of caspase-3 protease in Chang cells. 5. Synergistic increase in apoptotic cytotoxicity by combination of two medications was dependent on the expression of Fas in cancer cells. Conclusions : Combination of adriamycin and Palginhonhapwhajucwhan significantly augmented apoptotic cytotoxicity of Fas-positive cells such as Chang and HL-60 cells via acticaton of apoptosis signaling pathway.

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Comparison of Meat Characteristics between Korean Native Duck and Imported Commercial Duck Raised under Identical Rearing and Feeding Condition

  • Muhlisin, Muhlisin;Kim, Dong Soo;Song, Yeong Rae;Kim, Hong Rae;Kwon, Hyung Joo;An, Byoung Ki;Kang, Chang Won;Kim, Hak Kyu;Lee, Sung Ki
    • Food Science of Animal Resources
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    • 제33권1호
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    • pp.89-95
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    • 2013
  • This research was conducted to compare the meat characteristics of Korean native duck and imported commercial duck. The Korean native ducks and imported commercial ducks (broiler duck: Grimaud) were raised under identical rearing and feeding conditions for 8 wk and 6 wk, respectively. At the end of the rearing period, ten ducks from each group were slaughtered, and breast and leg meat were obtained 24 h after slaughtering for analyses of meat characteristics. The results showed that the breast of Korean native ducks contained lower moisture and fat, and higher protein and water holding capacity (WHC) than those of imported commercial ducks (p<0.05). The breast of Korean native ducks also had higher CIE $a^*$ and lower CIE $L^*$ (p<0.05). After cooking, the breast meat of Korean native ducks had higher shear-force, sensory attributes of texture, taste and overall likeness (p<0.05). Also, the breast meat of Korean native ducks contained a higher percentage of palmitic acid ($C_{16:0}$) and arachidonic acid ($C_{20:4}$) (p<0.05) than those of imported commercial ducks. Furthermore, the leg meat of Korean native ducks contained higher percentages of total unsaturated fatty acid and lower percentages of total saturated fatty acid (p<0.05). It is concluded that the meat from Korean native ducks, especially breast meat, had better quality parameters and contained higher amounts of unsaturated fatty acids.

Two Cases Presenting Thoracic Complications of Deep Neck Infection (심부 경부 감염 후 합병된 흉강내 감염 2예)

  • Yeoum, Moon-Sun;Kim, Tae-Hee;Kim, Do-Youn;Jung, Soo-Jin;Lee, Chang-Bai;Lee, Hye-Jin;Lee, Jin-Hwa;Kim, Hyae-Young;Park, Young-Sik;Kim, Myung-Rae;Chang, Jung-Hyun
    • Tuberculosis and Respiratory Diseases
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    • 제48권4호
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    • pp.543-549
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    • 2000
  • The incidence of deep neck infection has been reduced by modern antibiotic therapy. Life-threatening deep neck infection of odontogenic or upper airway origin may extend to the thorax. Early diagnosis, administration of the potent antibiotics, and complete debridement and drainage are essential to improve the chances for survival in these very ill patients. We report two cases of deep neck infection which were complicated by thoracic infection such as mediastinitis, pericarditis, and empyema as a result of descending infection.

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Motility, Fertilizability and Subsequent Embryonic Development of Frozen-thawed Spermatozoa derived from Epididymis in Hanwoo

  • Yang, Byoung-Chul;Kang, Sung-Sik;Park, Chang-Seok;Kim, Ui-Hyung;Kim, Hyeong-Cheol;Jeon, Gi-Jun;Kim, Sidong;Lee, Seok-Dong;Lee, Hyun-Jae;Cho, Sang-Rae
    • Journal of Embryo Transfer
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    • 제30권4호
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    • pp.271-276
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    • 2015
  • The aim of the study was to investigate the ability of sperm derived from the epididymis in regard to sperm motility, sperm penetration to oocyte and subsequent development of the embryo. Frozen-thawed sperm from epididymis showed similar percentage of motile sperm (VSL ${\geq}25{\mu}m/sec$) as compared to that of commercial sperm (control). Sperm penetration of frozen-thawed epididymal and commercial sperm was not significantly different. Moreover, cleavage and blastocyst rates were similar in both epididymal and control. Sperm derived from the epididymis also showed fertilizability and subsequent embryonic development.

A Case of Congenital Malaria (신생아에서 발생한 선천성 말라리아 1례)

  • Lee, Eun Jin;Chang, Hyen Ho;Lee, Chong Guk;Cho, Chong Rae
    • Clinical and Experimental Pediatrics
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    • 제46권8호
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    • pp.821-825
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    • 2003
  • Malaria is known to have been eradicated for a few decades through the persistent efforts of the national health program in South Korea. However, malaria caused by Plasmodium vivax has started to reappear incidiously among military personnel near to the De-militarized Zone since 1993. From that time on the number of malarial cases have increased abruptly year by year. However, congenital malaria in a neonate is extreamly rare in Korea. We experienced one case of malaria in a neonate who was born from a mother affected by malaria. This neonate was born at $33^{+3}$ weeks of gestational age. Here we present this case with a brief review of the literature.

A Predictive Morphological Analyzer, A Part-of-Speech Tagger Based on Joint Independence Model, and A Fast Noun Extractor (예측 기반 형태소 분석기와 결합 독립 모형 기반 품사 태거 및 고속 명사 추출기)

  • Lee, Sang-Zoo;Park, Bong-Rae;Kim, Jin-Dong;Ryu, Won-Ho;Lee, Do-Gil;Rim, Hae-Chang
    • Annual Conference on Human and Language Technology
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    • 한국정보과학회언어공학연구회 1999년도 제11회 한글 및 한국어 정보처리 학술대회 및 제1회 형태소 분석기 및 품사태거 평가 워크숍
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    • pp.145-150
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    • 1999
  • 본 논문에서는 한국어 자연어 정보처리 기술 표준화를 위한 형태소 분석기 및 품사 태거 평가 대회(MATEC99)에 참여한 고려대학교의 형태소 분석기, 품사 태거, 그리고 명사 추출기를 설명하고 평가 결과를 기술한다. 형태소 분석기는 입력된 어절을 우에서 좌로 분석하며 각 상태에 대한 예측 정보를 활용하여 불필요한 분석 후보에 대한 탐색을 수행하지 않도록 한다. 품사 태거로는 띄어쓰기를 고려한 형태소 품사 2-그램 확률과 띄어쓰기를 고려한 형태소 어휘-품사 3-그램 어휘 확률을 이용하는 결합 독립 모형을 사용한다. 고속 명사 추출기는 고속의 FST 사전과 한국어 특성을 반영한 휴리스틱을 이용한다.

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THE ACCURACY OF COMPUTERIZED PREDICTION OF THE SOFT TISSUE PROFILE AFTER SURGICAL CORRECTION OF MANDIBULAR PROGNATHISM (하악전돌증의 악교정술시 컴퓨터를 이용한 술후예견과 실상과의 차이에 관한 연구)

  • Lee, Chang-Kug;Kim, Kyung-Wook;Kim, Myeong-Rae;Lee, Jae-Hoon
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제26권4호
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    • pp.383-390
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    • 2000
  • The purpose of this study was to compare the soft tissue movements in facial profile predicted by a computer package with those that had actually accured following a sagittal split ramal osteotomy. The reliability of predicting the results of orthodontic surgical treatment was analysed. The study was based on the serial records of 30 consecutive patients who had been treated by means of a sagittal split ramal osteotomy. The serial lateral cephalometric radiographs used for the study were taken at the following stages: immediate preoperative : immediate postoperative : 6 months postoperative. A superimposition T1, T2-3 was generated to allow visual comparision. The results can be considered in relation to four important parts of the facial profile :the nose, upper lip, lower lip, and chin. The nose & Upper lip:The amount of movement of the upper lipwas not badly predicted for the average case. The lower lip: There was a significant trend over the whole sample for vertical positionof the lower lip to be less well predicted. The chin: The soft tissue movements of the chin were well predicted.

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Design of 154kV, 1GVA HTS Cable (154kV, 1GVA 초전도케이블 설계)

  • Cho, Jeon-Wook;Sim, Ki-Duck;Kim, Seok-Ho;Lee, Su-Kil;Jang, Hyun-Man;Choi, Chang-Yeol;Lee, Kuen-Tae;Yang, Byeung-Mo;Kim, Seung-Rae
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 한국전기전자재료학회 2010년도 하계학술대회 논문집
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    • pp.192-192
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    • 2010
  • DAPAS (Development of Advanced Power system by Applied Superconductivity technologies) program that the, superconductivity national program has been started one of the 21C frontier programs from 2001 in Korea. The 3rd phase of DAPAS program was started at April 2007, and the ultimate goal of HTS cable project is to develop 154kV, 1GVA class HTS cable. The structure of 154kV, 1GVA HTS cable is single core with cold dielectric insulation. The cable core consists of the former, conduction layer, electrical insulation layer, shielding layer. The cable cryostat consists of two corrugated seamless aluminum tubes as its high sealing reliability, the tubes separated through a spacer arrangement. Outdoor termination was developed by LS cable and cryogenic system by CVE for 154kV, 1GVA class HTS cable. The 154kV, 1GVA HTS cable will be installed and be tested in KEPCO Gochang Testing Center from June 2010.

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