• 대한한방내과학회지
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• 제33권4호
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• pp.533-542
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• 2012

Objectives : We try to compared the efficacy of six herbal medicines, Rhizoma Alismatis (RA), Fructus Crataegi (FC), Fructus Lycii (FL), Radix Curcumae (RC), Radix Salviae Miltiorrhizae (RSM), and Herba Artemisiae Scopariae (HAS), constituting KHchunggan-tang which was previously proven to be hepatoprotective on non-alcoholic fatty liver disease with combined properties of cellular steatosis, ROS production, and cytoprotection. Methods : HepG2 cells were pretreated with aqueous extracts of the six herb medicines at concentrations of 1, 10, 50 and 100 ${\mu}g/ml$ each, and treated with 0.5 mM palmitate consecutively. After 21 hrs, cell viability was assessed using MTT assay, and the percentage of cells with sub-G1 DNA content was measured using fluorescence-activated cell sorting after propidium iodide staining. Results : The first three extracts, RA, FC, and FL restored cell viability reduced by palmitate in MTT assay, and RA, FC, FL and RC inhibited palmitate-induced apoptosis in sub-G1 analysis. FL showed relatively weak potential only at tested maximal dose, and RA showed the greatest higher efficacy on this experimental cellular model of nonalcoholic fatty liver disease. Conclusions : According to this comparative experiment, Rhizoma Alismatis seems to have the most powerful potential among the six herbs constituting KHchunggan-tang, and consecutive further study seems to be required for more standardized and effective clinical application of KHchunggan-tang for treatment of non-alcoholic fatty liver disease.

• 대한환경공학회지
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• 제39권8호
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• pp.456-461
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• 2017

본 연구에서는 전기방사를 통해 제조되는 dope solution의 원료인 다양한 Polymer [PAN (Polyacrylonitrile), PU (Polyuretane), PSU (Polysulfone)]와 용매[NMP (N-methyl-2 pyrrolidone), DMF (Dimethylformamide)]를 이용하여 다양한 물성의 나노섬유 물질을 구현하고, 이의 flux 특성과 SS (Suspended Solids) 분리 성능을 평가하여 제조된 섬유의 수처리 분리막으로서의 적용성을 확인하였다. 또한 SEM 분석을 통해 제조된 소재의 표면 분석을 수행하여, 섬유의 직경, 균일성 및 직진성 확인을 통해 flux, SS 분리 성능의 원인을 확인하였다. 추후 나노섬유 수처리 분리막 제조공정에서의 첨가제 투입을 통해 막 파울링, 기계적 강도 등의 문제를 해결할 수 있을 것으로 예상되며, 촉매 기능이 첨가된 수처리용 분리막 제조를 위한 기초 인자로써 활용될 수 있을 것으로 기대된다.

• Nuclear Engineering and Technology
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• 제47권3호
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• pp.380-387
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• 2015

A lead slowing-down spectrometer (LSDS) system is a promising nondestructive assay technique that enables a quantitative measurement of the isotopic contents of major fissile isotopes in spent nuclear fuel and its pyroprocessing counterparts, such as $^{235}U$, $^{239}Pu$, $^{241}Pu$, and, potentially, minor actinides. The LSDS system currently under development at the Korea Atomic Energy Research Institute (Daejeon, Korea) is planned to utilize a high-flux ($>10^{12}n/cm^2{\cdot}s$) neutron source comprised of a high-energy (30 MeV)/high-current (~2 A) electron beam and a heavy metal target, which results in a very intense and complex radiation field for the facility, thus demanding structural shielding to guarantee the safety. Optimization of the structural shielding design was conducted using MCNPX for neutron dose rate evaluation of several representative hypothetical designs. In order to satisfy the construction cost and neutron attenuation capability of the facility, while simultaneously achieving the aimed dose rate limit (< $0.06{\mu}Sv/h$), a few shielding materials [high-density polyethylene (HDPE)eBorax, $B_4C$, and $Li_2CO_3$] were considered for the main neutron absorber layer, which is encapsulated within the double-sided concrete wall. The MCNP simulation indicated that HDPE-Borax is the most efficient among the aforementioned candidate materials, and the combined thickness of the shielding layers should exceed 100 cm to satisfy the dose limit on the outside surface of the shielding wall of the facility when limiting the thickness of the HDPE-Borax intermediate layer to below 5 cm. However, the shielding wall must include the instrumentation and installation holes for the LSDS system. The radiation leakage through the holes was substantially mitigated by adopting a zigzag-shape with concrete covers on both sides. The suggested optimized design of the shielding structure satisfies the dose rate limit and can be used for the construction of a facility in the near future.

• Nuclear Engineering and Technology
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• 제42권5호
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• pp.576-581
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• 2010

KAERI (Korea Atomic Energy Research Institute) fabricated MOX (Mixed Oxide) fuel pellets as a cooperation project with PSI (Paul Scherrer Institut) for an irradiation test in the Halden reactor. The MOX pellets were fitted into fuel rods that included instrumentation for measurement in IFE (Institutt for Energiteknikk). The fuel rods were assembled into the test rig and irradiated in the Halden reactor up to 50 MWd/kgHM. The irradiated fuel rods were transported to the IFE, where ceramography was carried out. The fuel rods were cut transversely at the relatively higher burn-up locations and then the radial cross sections were observed. Micrographs were analyzed using an image analysis program and grain sizes along the radial direction were measured by the linear intercept method. Radial cracks in the irradiated MOX were observed that were generally circumferentially closed at the pellet periphery and open in the hot central region. A circumferential crack was formed along the boundary between the dark central and the outer regions. The inner surface of the cladding was covered with an oxide layer. Pu-rich spots were observed in the outer region of the fuel pellets. The spots were surrounded by many small pores and contained some big pores inside. Metallic fission product precipitates were observed mainly in the central region and in the inside of the Pu spots. The average areal fractions of the metallic precipitates at the radial cross section were 0.41% for rod 6 and 0.32% for rod 3. In the periphery, pore density smaller than 2 ${\mu}m$ was higher than that of the other regions. The grain growth occurred from 10 ${\mu}m$ to 12 ${\mu}m$ in the central region of rod 6 during irradiation.

• 혜화의학회지
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• 제4권2호
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• pp.333-333
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• 1996

Chinese medicine is a precious treasure inherited from ancient ancestors. It is accredited for the prosperous growth of the Chinese nations. However, the descriptions of the herbs in the ancient herbal are not in detail and the great numbers of herbs used which grows in wide geographic areas together with various local folk names, new substitutes and new folk medicines had increased, many Chinese herbs are composed of herbs that are labeled with identical names but actually are of different origins and different grades. Similar situation had occurred in China, japan and Korea In Taiwan, misused Chinese crude drugs are also very common in the past. This phenomenon had caused a lot of confusion and had great influence the clinical efficacy of the treatment. In the past, Professor Hong Yen Hsu, Na Chi, Woei Song Kan and Kung Yin Yen had studied the origins of Chinese crude drugs in Taiwan based on the morphological identification and found that the origins of Ma-Tou-Ling, Pu-Kung-Yin, Tu-Chung, Wang-Pu-Liu-Hsing, Pan-lan-Ken, Niu-Chi, Fang-Chi, Huang-Chi, PienHsiu and Sha Wan-Tzi are different from that of the species used in mainland China. In order to assure the quality and clinical efficacy of the crude drugs, besides the traditional morphological methods, we bad recently combined modem chemical and pharma-cological methods to assess drug quality. Drugs that have been evaluated without effects should be abandoned. The species of those commonly misued crude drugs used in compound formula preparations are also identified Based on the pharmacological results, a suitable species is recommended so as to improve the clinical efficacy of those preparations. In this paper, we like to report our recent studies on Niu Chi(Achyranthis Bidentatae Radix, Cyathulae Radix and Strobilanthis Radix). Fang-Chi(Arstolochiae Fangchi Radix, Stephaniae Tetrandrae Radix and Cocculus Radix) and Huang-Chi(Astragali Radix and Hedysari Radix) using comparative pharmacognosy methods.

• 한국지리정보학회지
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• 제11권3호
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• pp.34-42
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• 2008

정확한 지리위치 좌표를 나타내는 기준점은 국가의 중요한 자산으로써 전국토의 측량과 기타 측량 사업에 사용되고 있다. 유비쿼터스 기술의 발전으로 위치정보는 우리 생활에서 중요한 역할을 하고 있다. 현재 RFID (Radio-Frequency Identification)와 같은 유비쿼터스 기술을 기준점 관리 시스템에 융합함으로써 관리의 효율성을 제고하기 위해 여러 분야에서 연구가 진행되고 있다. 그러나 기존의 연구에서는 데이터 관점에서 기준점 관리를 위한 호환성과 효율적인 검색에 대한 연구는 미비한 실정이다. 따라서, 본 논문에서는 온톨로지 기술을 사용하여 기준점 데이터를 효율적으로 검색하기 위한 데이터 모델링을 구축하고 그의 적용 방안에 초점을 두어 연구한다. 제안된 온톨로지 기반의 검색 시스템은 계층적 검색으로 사용자의 반복된 검색 수행을 줄일 수 있고, 연관 검색으로 검색 시간을 줄일 수 있는 장점이 있다. 또한, 사용자 인터페이스와 관련된 소스 코드를 수정하지 않고 카테고리와 속성의 항목을 편집할 수 있는 효과적인 검색 시스템 구축 방법을 제안한다.

• 센서학회지
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• 제11권1호
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• pp.48-53
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• 2002

강유전 물질인 $Pb_{0.99}[(Zr_{0.6}Sn_{0.4})_{1-x}Ti_x]_{0.98}Nb_{0.02}O_3$(PNZST) 박막을 10 mole%의 과잉 PbO가 첨가된 타겟을 이용하여 $La_{0.5}Sr_{0.5}CoO_3$(LSCO)/Pt/Ti/$SiO_2$/Si 기판상에 RF 마그네트론 스퍼터링 방법으로 증착하였다. Ti의 조성비를 변화시키면서 증착된 박막에 대하여 그 결정성과 전기적 특성을 조사하였다. 80 W의 RF 전력, $500^{\circ}C$의 기판온도에서 증착한 후, $650^{\circ}C$, 공기중에서 10초 동안 급속 열처리된 박막이 가장 우수한 페로브스카이트상으로 결정화되었다. 또한. Ti의 조성비가 10 mole%를 가지는 PNZST이 가장 우수한 결정성과 강유전 특성을 나타내었다. 이러한 박막으로 제작된 PNZST 커패시터는 약 $20\;{\mu}C/cm^2$정도의 잔류분극과 약 50 kV/cm 정도의 항전계를 나타내었으며, $2.2{\times}10^9$의 스위칭 후에도 잔류분극의 감소는 10% 미만이었다.

• 디자인학연구
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• 제19권3호
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• pp.59-70
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• 2006

Narratologists have long raised the question of how narrative theories could be applied to other disciplines that involve stories and storytelling. Focusing on recently revitalized concepts of space, sequence, and story, this article attempts to illustrate narrative constructions in various fields of arts and humanities and examine them particularly in typographical works. Through the concept of narrativity, this article highlights the prevalent uses of narrative in typography and scrutinizes the ways in which a sense of storyness is forming and emerging in some typographical works. Particularly emphasized are the importance of and interplay between the formal and cultural attributes of narrative that transform the spatial world of visual images to the temporal world of stories. Narrative is arguably the most familiar, interesting, and effective medium of communication regardless of age, race, and culture, and can be critically rethought to apply to typography and design.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2009년도 학술논문요약집
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• pp.53-54
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• 2009

The preliminary quantitative analysis of proliferation resistance for the five nuclear fuel cycles demonstrated that the thermal MOX fuel cycle is most vulnerable to proliferation due to the presence of pure $PuO_2$ in the fuel cycle, while the once-through fuel cycle has the highest proliferation resistance. The innovative next generation fuel cycles such as Pyro-SFR and Wet-SFR were found to have similar levels of proliferation resistance to that of the DUPIC fuel cycle which is believed to have proliferation resistance strong enough for commercial deployment. The sensitivity analysis also demonstrated the effectiveness of the proposed methodology in applying to existing and/or newly developing nuclear fuel cycles so as to improve the proliferation resistance characteristic of the fuel cycle systems.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송공학회 2011년도 하계학술대회
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• pp.184-187
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• 2011

본 논문에서는 화면내 예측의 계산 복잡도를 감소시키기 위한 방법을 제안한다. HM2.0 의 화면내 예측방법인 각도에 의한 예측(Angular prediction)은 예측 대상블록 내부의 각 샘플이 예측하기 위해 사용하는 참조샘플로부터 정수단위의 위치에 있지 않을 경우 참조 샘플들을 보간 하여 예측을 수행한다. 이러한 방법은 예측 대상 블록의 크기가 커질수록 보간 하는 횟수가 증가하고 계산 복잡도가 증가하는 단점이 있다. 제안하는 방법은 한번의 보간으로 복수의 샘플들을 예측함으로써 보간 횟수를 줄이고 결과적으로 계산의 복잡도를 줄인다. PU_32x32 에 대해 제안하는 방법을 적용하였을 경우, 보간하는 횟수는 HM2.0 대비 1/2 배 또는 1/4 배 가까이 감소하고 성능 저하는 High-Efficiency(HE)에서 0.1% 또는 0.2% 정도로 미미하게 나타났다.