• Journal of Pharmaceutical Investigation
• /
• v.21 no.2
• /
• pp.97-101
• /
• 1991

Six different O/W cream bases containing 4% ascorbic acid dipalmitate and two different O/W cream bases containing 1% ascorbic acid were prepared. Percutanceous absorption of ascorbic acid as well as safety were determined using rabbits. The stability of the creams was also tested at room temperature. Ascorbic acid concentrations in urines varied depending on the characteristics of cream bases used. The absorption of ascorbic acid was increased and sustained with the cream bases containing branched chain esters of fatty acid instead of natural oils used currently. The excretion level of ascorbic acid in urine was high with the cream base including nonionic surfactants and a small quantity of natural oils. The creams containing nonionic surfactants showed excellent stability, while those containing anionic surfactants were not stable in terms of pH, odor and coloring test at room temperature during six months. But, the two creams containing ascorbic acid were unstable. All the cream bases tested showed good safety.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2016.10a
• /
• pp.489-492
• /
• 2016

Transportation in the logistics, many business organizations are engaged in monitoring and tracking the vehicles in order to improve logistics services, reduce expenses and secure security in cargo transportation. It is saving time and money by tracking and monitoring vehicles which transport cargo in supply chain of logistics. Therefore the main issue of delivery flow is to improve services, and ensure the safety in transportation system. This article suggests the tracking and monitoring model to keep safety transports on ICT network. It focuses on precise delivery control by monitoring and tracking vehicles to save time and costs. The status of product movement is analyzed for proper decision making. The vehicle embedded with RFID is automatically tracked in the movement process by tracking and monitoring model. The main role keeps safety tracking to reduce costs and to deliver products at proper time and location.

• Nuclear Engineering and Technology
• /
• v.55 no.3
• /
• pp.861-869
• /
• 2023

This article proposes a novel approach to measure the performance of Safety-Critical Systems (SCS). Such systems contain multiple processing nodes that communicate with each other is modeled by a Petri nets (PN). The paper uses the PN for the performance evaluation of SCS. A set of ordinary differential equations (ODEs) is derived from the Petri net model that represent the state of the system, and the solutions can be used to measure the system's performance. The proposed method can avoid the state space explosion problem and also introduces new metrics of performance, along with their measurement: deadlock, liveness, stability, boundedness, and steady state. The proposed technique is applied to Shutdown System (SDS) of Nuclear Power Plant (NPP). We obtained 99.887% accuracy of performance measurement, which proves the effectiveness of our approach.

• Journal of Microbiology and Biotechnology
• /
• v.34 no.5
• /
• pp.1101-1108
• /
• 2024

Earlier studies have validated the isolation of extended-spectrum beta-lactamase-producing Salmonella (ESBL-Sal) strains from food. While poultry is recognized as a reservoir for Salmonella contamination, pertinent data regarding ESBL-Sal remains limited. Consequently, the Ministry of Food and Drug Safety has isolated Salmonella spp. from retail meat and evaluated their antibiotic susceptibility and genetic characteristics via whole-genome sequencing. To further elucidate these aspects, this study investigates the prevalence, antibiotic resistance profiles, genomic characteristics, and homology of ESBL-Sal spp. obtained from livestock-derived products in South Korean retail outlets. A total of 653 Salmonella spp. were isolated from 1,876 meat samples, including 509 beef, 503 pork, 555 chicken, and 309 duck samples. The prevalence rates of Salmonella were 0.0%, 1.4%, 17.5%, and 28.2% in the beef, pork, chicken, and duck samples, respectively. ESBL-Sal was exclusively identified in poultry meat, with a prevalence of 1.4% in the chicken samples (8/555) and 0.3% in the duck samples (1/309). All ESBL-Sal strains carried the bla_CTX-M-1 gene and exhibited resistance to ampicillin, ceftiofur, ceftazidime, nalidixic acid, and tetracycline. Eight ESBL-Sal isolates were identified as S. Enteritidis with sequence type (ST) 11. The major plasmid replicons of the Enteritidis-ST11 strains were IncFIB(S) and IncFII(S), carrying antimicrobial resistance genes (β-lactam, tetracycline, and aminoglycoside) and 166 virulence factor genes. The results of this study provide valuable insights for the surveillance and monitoring of ESBL-Sal in South Korean food chain.

• The Journal of The Korea Institute of Intelligent Transport Systems
• /
• v.10 no.4
• /
• pp.36-43
• /
• 2011

The forward collision of vehicles in high speed can cause a chain collisions and high fatality rate. Most of the forward collisions are caused by insufficient braking distance due to detection time of driver and safe distance. Also, accumulated detection time of driver is cause of chain collisions after the forward collision. The FVCWS prevents the forward collision by maintaining the safety distance inter-vehicle and reducing detection time of driver. However the FVCWS can cause chain collisions because the system that interacts only forward vehicle has accumulated detection time of driver. In this paper, we analyze forward and chain collisions of normal vehicles and FVCWS vehicles on static traveling scenario. And then, we analyze and compare V2V based FVCWS with them after explaining the system. The V2V FVCWS reduces detection time of driver alike FVCWS as well as remove accumulated detection time of driver by broadcasting emergence message to backward vehicles at the same time. Therefore, the system decrease possibility of forward and chain collisions. All backward normal vehicles and 3~4 backward FVCWS vehicles have possibility of forward and chain collisions in result of analysis. However V2V FVCWS vehicles almost do not chain collisions in the result.

• Journal of Digital Convergence
• /
• v.20 no.2
• /
• pp.9-20
• /
• 2022

Supply chain attacks target critical infrastructure, causing large amounts of damage and evolving into a threat to public safety and national security. Accordingly, when establishing cybersecurity strategies and policies, supply chain risk management is specified to enhance security, and the US Biden administration recently issued the Executive Order on Improving the Nation's Cybersecurity, SBOM was mentioned as part of the guidelines for strengthening software supply chain security. If the government mandates SBOM and uses it as a security verification tool for supply chains, it can be affected by the domestic procurement system in the future and can be referenced when establishing a security system for domestic supply chains according to the progress of policy implementation. Accordingly, in this paper, countries that are promoting the SBOM policy as a way to strengthen the security of the software supply chain were selected and analyzed with a focus on related cases. In addition, through comparison and analysis of foreign SBOM policy trends, methods for using domestic SBOM in terms of technology, policy, and law were considered. As the value of using SBOM as a supply chain integrity/transparency verification tool is expected in the future, it is necessary to continuously identify trends in the establishment of international standardization and policy development for SBOM and study the standard format.

• Journal of Digital Convergence
• /
• v.10 no.10
• /
• pp.295-300
• /
• 2012

Various forward collision warning algorithms have studied in order to protect a car accident. For this, in general, algorithms using an external device such as a camera and sensor generate a forward collision warning. However, if using the external device, it can occur errors due to device characteristics when there is rain or fog. Also, the prevention of a chain-reaction collision is insufficient because the system generates a warning in case of only vehicle having a forward collision danger. If it combines the vehicle safety communications, the method becomes a solution to protect a chain-reaction collision. So, In this paper, we proposes a improved forward collision warning algorithm using the wireless communication technique, driver's information, breaking distance, and velocity. And we compare and analyze our algorithm and previous algorithms.

• Journal of Microbiology and Biotechnology
• /
• v.25 no.9
• /
• pp.1460-1466
• /
• 2015

In this study, the prevalence of Shiga toxin-producing Escherichia coli (STEC) was investigated among raw meat or meat products from slaughterhouses and retail markets in South Korea, and their potential for antibiotic resistance and virulence was further analyzed. A total of 912 raw meats, including beef, pork, and chicken, were collected from 2008 to 2009. E. coli strains were frequently isolated in chicken meats (176/233, 75.9%), beef (102/217, 42.3%), and pork (109/235, 39.2%). Putative STEC isolates were further categorized, based on the presence or absence of the Shiga toxin (stx) genes, followed by standard O-serotyping. Polymerase chain reaction assays were used to detect the previously defined virulence genes in STEC, including Shiga toxins 1 and Shiga toxin 2 (stx1 and 2), enterohemolysin (ehxA), intimin (eaeA), STEC autoagglutination adhesion (saa), and subtilase cytotoxin (subAB). All carried both stx1 and eae genes, but none of them had the stx2, saa, or subAB genes. Six (50.0%) STEC isolates possessed the ehxA gene, which is known to be encoded by the 60-megadalton virulence plasmid. Our antibiogram profiling demonstrated that some STEC strains, particularly pork and chicken isolates, displayed a multiple drug-resistance phenotype. RPLA analysis revealed that all the stx1-positive STEC isolates produced Stx1 only at the undetectable level. Altogether, these results imply that the locus of enterocyte and effacement (LEE)-positive strains STEC are predominant among raw meats or meat products from slaughterhouses or retail markets in Korea.

• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2012.11a
• /
• pp.229-231
• /
• 2012

The supply chain in plant construction project can be defined as a network combined between elements which is engineering, procurement, construction, start-up. For successfully leading construction project, close relation and mutual cooperation should be preceded and Supply Chain Management(SCM) system is needed to improve the relation. In particular, because safety is a top priority for the companies work in the construction of Nuclear Power Plant(NPP), it is necessary to control all parties realated with NPP construction systematically. In this situation, it is important to purchase high-quality equipment in timely manner by developing Integrated cooperative systems. Therefore, this study aimed to propose developing solutions of SCM such as JIT and Envelop Design system, which can reduces difficulties of decision making between the parties involved in the project and will increase the efficiency of the engineering process in NPP.

• Korean Journal of Veterinary Service
• /
• v.30 no.3
• /
• pp.313-319
• /
• 2007

Avian adenoviruses are diverse group of pathogens and recently hydropericardium hepatitis syndrome (HHS) Is an important, emerged disease of poultry. Particularly 2-3 weeks old age broilers increased mortality ranging from 20-30% and brown native chicken 3-7 weeks sudden onset with mortality 20-50%, typically development secondary infection. The infection chicken shows liver enlarged, pale and straw- colored fluid is present in the sac surrounding the heart. Histopathological positive samples have necrotic foci and basophilic intranuclear inclusion bodies in the hepatocytes and polymerase chain reaction (PCR) was useful for detect the fowl adenovirus (FAV) associated with HHS.