• International Journal of Industrial Entomology and Biomaterials
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• 제8권2호
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• pp.189-194
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• 2004

Amylase isozyme based three multivoltine viz., N+p, Np, N+ $p^{cho}$ and two bivoltine-D6+p, D6p syngenic lines (Syn. L) were developed from germplasm (GP) stocks Nistari (N) and D6 respectively. haemolymph isozyme pattern at pH 7.0 and 8.5 depicted a total 11 number (Am $y_{1 to 6}$ at pH 7.0 and Am $y^{l to 5}$ at pH 8.5) of native proteins (NP) of various sizes are amylase isozyme expressers. Among eleven NPs, two NPs of 770 kDa (Am $y^{6}$ at pH 7.0) and 376 kDa (Am $y^3$ at pH 8.5) are $\alpha$-amylase expressers and remaining NPs of 370, 364, 350, 329 and 274 kDa at pH 7.0 and 206, 292, 416, 725 kDa at pH 8.5 are $\beta$-amylase expressers. Accordingly, digestive juice amylase isozyme pattern at aforesaid pH also depicted a total number of 10 NPs (Am $y^{1 to 5}$) at each pH 7.0 and 8.5 are amylase expressers of which NP of 387 kDa (Am $y^4$ at pH 7.0) and 780 kDa (Am $y^{5}$ at pH 8.5) are a-amylase expresser. Remaining NPs of 338,297 ＆ 216 kDa at pH 7.0 and 370, 341, 329 ＆302 kDa at pH 8.5 are $\beta$-amylase expresser. Recurrent backcross lines (RBL) viz., N+pRBL and NpRBL were developed through introgression of high shell weight character (a multigenic trait) to be used further for congenic line (Con. L) development and to understand any association with introgressed character. Isozyme pattern in haemolymph of RBLs depicted only one $\alpha$-amylase of 770 kDa at pH 7.0 and 376 kDa at pH 8.0 with three and four respective $\beta$-amylase bands but in bivoltine lines numbers of $\beta$-amylase bands vary between 1 to 2 at aforesaid pH. Variability was also observed in digestive juice of multivolitine and its RBLs but bivoltine lines express null activity at both pH except appearance of one very week $\alpha$-amylase band D6+p at pH 8.5. Overall study suggests that not a single NP at both pH is common for expression of any band of amylase isozyme i.e., a totally different set of proteins are the amylase isozyme expresser at specific pH and no molecular factor of amylase is associated in developed RBLs which showed improvement on survival, single cocoon shell weight (SCSW) and single filament length over receptor parents.s.s.s.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2011년도 춘계학술대회 논문집
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• pp.109-116
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• 2011

In this paper, we investigate the scheme to improve the position accuracy using GNSS(Global Navigation Satellite System). Then we configure the real-time DGPS environment with use of NTRIP currently being in service on the DGNSS central office of MLTM(Ministry of Land and Transportation). And we verify the improvement of position accuracy and the continuity of GPS correction data through the DGPS test in Chungbuk line and Joongang line.

• International Journal of Industrial Entomology and Biomaterials
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• 제8권1호
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• pp.107-112
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• 2004

The combining abilities in the 5 newly evolved thermo tolerant breeds viz., SR6, SR7, SR8 SR9 and SR10 of silkworm Bombyx mori L. and their 15 hybrids were made in a line${\times}$tester crossing programme. Data were analysed for seven quantitative traits i.e., pupation rate, cocoon yield, cocoon weight, cocoon shell weight, cocoon shell ratio, filament length and raw silk percentage under optimum room temperature $(25{\pm}{1^{\circ}C})$ conditions (In case of high temperature $(36{\pm}{1^{\circ}C})$ stress conditions five economic traits except filament length and raw silk percentage) with 3 widely adapted testers i.e., KA, CSR2 and CC1 as lines (females) and testers (males) respectively. The performance at high temperature and low humidity conditions aye only taken into consideration for selecting the best lines/hybrids. Among the lines SR6 exhibited positive General combining ability (GCA) effects for pupation rate, cocoon yield, cocoon weight and cocoon shell ratio traits, followed by SR7 for pupation rate, cocoon yield and cocoon shell weight and cocoon shell ratio. Among testers, KA exhibited positive GCA effects for two quantitative traits cocoon yield, cocoon weight and CSR2 for cocoon shell weight and cocoon shell ratio under adverse temperature conditions. The hybrid SR6${\times}$CC1 and SR7${\times}$CSR2 exhibited significant positive Specific combining ability (SCA) effects for majority of the traits in high temperature stress conditions of rearing. The better parent value of heterosis(Heterobeltiosis) was exhibited by the hybrid SR6${\times}$CC1 for pupation rate, cocoon yield, cocoon weight and cocoon shell weight and SR7${\times}$CSR2 for all the trails evaluated under high temperature conditions. Based on the results, the lines SR6 and SR7 was judged as best combiners and the hybrids SR6${\times}$CC1 and SR7${\times}$CSR2 can be selected for commercial exploitation in tropical climate.

• 천문학회보
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• 제41권2호
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• pp.63.3-63.3
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• 2016

We present the two-dimensional distribution of stellar populations in five E+A galaxies from GMOS-N/IFU spectroscopy (GN-2015B-Q-15). Numerical simulations demonstrated that E+A galaxies formed by major mergers contain young stellar populations (e.g. A-type stars) that are centrally-concentrated within scales of 1 kpc. However, several IFU studies reported that A-type stars are widely distributed on ${\gg}$ 1kpc scales. In contrast, Pracy et al. (2013) found a central concentration of A-stars and strong negative Balmer absorption line gradients within 1 kpc scales for local (z < 0.03) E+A galaxies. They claimed that previous studies failed to detect the central concentration because the E+A galaxy samples in previous studies are too far (z ~ 0.1) to resolve the central kpc scales. To verify Pracy et al.'s argument and the expectation from simulations, we selected five E+A galaxies at 0.03 < z < 0.05. Furthermore, we selected the targets in the mid-infrared green valley (Lee et al. 2015). Thanks to good seeing (${\sim}0.4^{{\prime}{\prime}}{\simeq}0.33kpc$) of our observation, we are able to resolve the central 1 kpc region of our targets. We found that all five galaxies have negative Balmer line gradients, but that three galaxies have flatter gradients than those reported in Pracy et al. We discuss the results in relation with galaxy merger history.

• 대한치과기공학회지
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• 제15권1호
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• pp.89-94
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• 1993

The tooth size and shape of the permanent incisor teeth have been studied and analyzed about the mean size, S.D, S.E, etcs and percentage from stone model of 100 Korean male and 74 Korean female. The results were as follows. 1. The crown length of permanent incisor teeth were longer in males than in females statistical differences of males and female were not found. 2. the mesio-distal diameters of permanent incisor teeth were larger in males than in females and statistical differences of males and females were found in mandibular lateral incisor and the bigest were max. central incisor, 2nd max. lateral incisor, 3rd man. lateral incisor and the smallest were man. central incisor. 3. The square form in max. central incisor was the greatest percentage and the tapering form in max. lateral incisor and man, incisor was the greatest percentage but tapering form and ovoid form and other shape were found in max. lateral at the same ratio. 4. Concerning the labial developmental groove "midium" was the greatest percentage in the max. central incisor and "low" was the greatest percentage in the man incisor. Concerning the incisal line, straight line was the greatest percentage in the max, incisor and man, incisor and concerning the lingual tubercle "none" was the greatest percentage in the max. incisor. 5. In comparison between left side and right side of incisor, the ratio of same shape ware 22.4%-36.2% but similar or dissimilar cases were more frequently found.

• 한국지역지리학회지
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• 제15권1호
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• pp.67-85
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• 2009

중앙아시아 횡단철도는 가스피해 횡단철도, 카자린스크 철도, 투르케스탄-시베리아 철도, 카자흐스탄 횡단철도 등으로 구성된다. 중앙아시아 인구의 약 1/5에 해당하는 주민들이 이 철도를 중심으로 거주하고 있으며, 중앙아시아 경제의 70%정도가 이 횡단철도를 기반으로 하고 있다. 유라시아의 심장지역으로 간주되고 있는 중앙아시아 횡단철도의 건설은 해양세력과의 지정학적 경쟁, 변경지역과 중심지역간의 연계 강화 및 중앙아시아 경제의 특성화가 주 목적이었다. 구소련의 붕괴 이후 중앙아시아 각국의 모든 철로망이 주로 러시아와 연계를 맺고 있지만, 그 외 인근국가들과의 연계망이 미흡한 상태에 있다. 장기적으로 중앙아시아 횡단철도의 발전을 위해 해결해야 할 과제가 많지만, 그럼에도 불구하고 동서로는 동아시아와 유럽을, 그리고 남북으로는 러시아/발틱해와 인도양/페르시아만을 연결하는 대륙의 교량으로서의 역할은 여전히 유효하다.

• International Journal of Stem Cells
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• 제15권2호
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• pp.217-226
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• 2022

Background and Objectives: Stroke is the most common cause of human death and functional disability, resulting in more than 5 million deaths worldwide each year. Bone marrow mesenchymal stem cells (BMSCs) are a kind of stem cell that are able to self-renew and differentiate into many types of tissues. Therefore, BMSCs have the potential to replace damaged neurons and promote the reconstruction of nerve conduction pathways and connective tissue. However, it remains unknown whether transplanted BMSCs promote angiogenesis or improve the tissue microenvironment directly or indirectly through paracrine interactions. This study aimed to determine the therapeutic effect of BMSCs on ischemic stroke with hypertension in a rodent model and to explore the possible mechanisms underlying any benefits. Methods and Results: Middle cerebral artery occlusion was used to establish the experimental stroke model. The area of cerebral infarction, expression of vascular endothelial growth factor (VEGF) and glial cell line-derived neurotrophic factor (GDNF), and increment of astrocyte were measured by TTC staining, western blot, real-time quantitative polymerase chain reaction (RT-qPCR) and immunocytochemistry. The results showed a smaller area of cerebral infarction and improved neurological function scores in animals treated with BMSCs compared to controls. The results of RT-qPCR and western blot assays showed higher expression of VEGF and GDNF in BMSC-treated animals compared with controls. Our study also showed that one round of BMSCs transplantation significantly promoted the proliferation of subventricular zone and cortical cells, especially astrocytes, on the ischemic side following cerebral ischemia. Conclusions: Above findings support that BMSCs have therapeutic effects for ischemic stroke complicated with hypertension, which may occur via up-regulated expression of VEGF and GDNF and reduction of neuronal apoptosis, thereby promoting the recovery of nerve function.

• Mycobiology
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• 제37권1호
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• pp.21-27
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• 2009

In the present study, the anti-cancer effects of ginseng fermented with Phellinus linteus (GFPL) extract were examined through in vitro and in vivo assays. GFPL was produced by co-cultivating ginseng and Phellinus linteus together. Ginsenoside Rg3, Rh1 and Rh2 are important mediators of anti-angiogenesis and their levels in GFPL were enriched 24, 19 and 16 times, respectively, more than that of ginseng itself through the fermentation. GFPL exhibited distinct anti-cancer effects, including growth inhibition of the human lung carcinoma cell line A549, and promotion of immune activation by stimulating nitric oxide (NO) production in Raw 264.7 cells. Further evidence supporting anti-cancer effects of GFPL was its significant prolongment of the survival of B16F10 cancer cell-implanted mice. These results suggest that the GFPL may be a candidate for cancer prevention and treatment through immune activation and anti-angiogenic effects by enriching Rg3, Rh1 and Rh2.

• Archives of Pharmacal Research
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• 제21권5호
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• pp.610-614
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• 1998

DW-116, [1-(5-fluoro-2-pyridyl)-6-fluoro-7-(4-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquino-line-3-carboxylic acid hydrochloride}, is a new quinolone antibiotic with a broad antibacterial spectrum against G(+) and G(-) bacteria. DW-116 was evaluated for the immunomodulating activities, which is one of the efforts to investigate the mechanism of action related to the good in vivo antibacterial efficacy. The results of in vitro studies revealed there was no statistically significant increase in B and T lymphocyte proliferation. But the results of in vivo studies showed that the number of plaque forming cells (PFC), the amount of polyclonal antibodies and delayed-type hypersensitivity (DTH) were significantly increased after the repeat administration with 12 and 60 mg/kg of DW-116. Taken together, these results proposed that immunostimulting effect of DW-116 could be one of the action mechanisms for demonstrating in vivo antibacterial activities under these experimental conditions.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2000년도 봄 학술발표회논문집
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• pp.357-364
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• 2000

The three main processes involved in the design of stressed membrane surface are surface form-finding, stress analysis and cutting pattern generation. The last process, cutting pattern generation, is considered as a very important procedure in the aspect of the practical design for the fabric membrane surface. In this paper, The cutting pattern generation technique using the geodesic line algorithms is first introduced. And the numerical examples resulting from this technique are presented. Cable elements are used for the approximating membrane surface and two kinds of model, square line and central line model, are used in pattern generation. Finally, a number of different cutting pattern generation for the same membrane surface is carried out and the numerical results are compared each