• Title/Summary/Keyword: Center for Korean Studies

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Analysis of Studies on Guibi-tang(Guipitang) for Fundamental Establishment of Evidence Based Medicine(EBM) (EBM 기반구축을 위한 귀비탕(歸脾湯) 연구 문헌 분석)

  • Kim, Jung-Hoon;Lee, Jun-Kyoung;Ha, Hye-Kyoung;Seo, Chang-Seob;Lee, Mi-Young;Lee, Ho-Young;Jung, Da-Young;Lee, Nam-Hun;Lee, Jin-Ah;Huang, Dae-Sun;Shin, Hyun-Kyoo
    • Journal of Oriental Neuropsychiatry
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    • v.20 no.3
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    • pp.205-216
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    • 2009
  • Objectives : To establish the fundaments for EBM of Traditional Korean Medicine, the papers on Guibi-tang(Guipitang) which were frequently used in medical institutions of Traditional Korean Medicine were analyzed through researching domestic and international literatures. Methods : The papers were classified by the year of publishment, by experimental methods, by laboratory animals used in biological experiment and by the kinds of studies on biological efficacy. Results : Of total 39 papers were registered in domestic journals. Since 1980, publishments of papers have continuously increased. The papers on biological studies were 34 volumes, clinical studies were 5 volumes. Biological studies mainly showed the effects of anti-stress, anti-oxidant, hemostasis, anti-osteoporosis, gastroprotection, reproductive ability, brain cell activity, radioprotection. And clinical studies showed improvements of fearful throbbing, memory and orientation, insomnia, vericose vein, schizophrenia. Conclusions : Guibi-tang(Guipitang) could be used to fortify the spleen, nourish the heart and then control the blood. However biological studies need to be conducted in accordance with clinical study and further clinical studies on randomized controlled trials should be proceeded.

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Systemic Review of Clinical Studies about Oriental Medical Treatment of Cancer in Korea (국내에 보고된 한국 한의학의 암치료 임상연구에 대한 계통적 고찰)

  • Park, Bong-Ky;Lee, Jong-Hoon;Cho, Chong-Kwan;Shin, Hyun-Kyu;Eom, Seok-Ki;Yoo, Hwa-Seung
    • The Journal of Internal Korean Medicine
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    • v.29 no.4
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    • pp.1061-1074
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    • 2008
  • Objectives : Recently, the number of cancer patients who use complementary and alternative medicine (CAM), including oriental medicine, are increasing. Also, evidence for efficacy and safety of cancer CAM is reported continuously. This study was designed to evaluate the quality of the published papers for clinical studies about oriental medical cancer treatment in Korea. Methods : We searched for clinical research papers on the websites of the Korean oriental medical society and subsidiary academies, Korean traditional knowledge portal. Koreanstudies information service system (KISS), etc. We used the reference words 'cancer', 'malignant tumor', 'leukemia', 'lymphoma', 'multiple myeloma', 'melanoma', etc, We then chose studies that had been presented between 1991 and 2008 and analyzed them by publication year, design, cancer type, intervention, subject and journal. Results : There were 86 clinical research papers that were published between 1991 and 2008. The number of clinical studies has increased in a time-dependent manner. Case reports and case series studies account for 78% of total clinical research. Studies of lung cancer account for 17%. Studies of cancer-related symptoms of cancer patients account for 38%. Studies of Hang-Am-Dan account for 33%. Studies published in the journal of the Korean Society of Oriental Internal Medicine account for 35%. Conclusion : The clinical research papers about oriental medicine are increasing over time, but most of the studies are retrospective case reports or case series. Well-designed and prospective clinical trials would be recommended to provide more reliable evidence.

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Bony fusion of the maxilla and mandible as a sequelae of noma: A rare case report

  • Bagewadi, Shivanand B.;Awasthi, Ujjwala Rastogi;Mody, Bharat M.;Suma, Gundareddy N.;Garg, Shruti
    • Imaging Science in Dentistry
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    • v.45 no.3
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    • pp.193-198
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    • 2015
  • Noma is a gangrenous disease of the orofacial region that leads to severe facial tissue destruction and is a significant cause of death among children. With the advent of modern antibiotics and improved nutrition, children with noma may survive into adulthood, but must face the challenge of undergoing repair of the sequelae of noma. This report describes a case of bony fusion of the maxilla and mandible in a 28-year-old female patient, which was a sequelae of a childhood case of noma.

Construction of 1H-15N Double Resonance Solid-State NMR Probe for Membrane Proteins in Aligned Bicelles

  • Park, Tae-Joon;Kim, Ji-Sun;Um, Seung-Hoon;Kim, Yong-Ae
    • Bulletin of the Korean Chemical Society
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    • v.31 no.5
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    • pp.1187-1191
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    • 2010
  • $^1H-^{15}N$ heteronuclear dipolar coupling solid-state NMR experiments on lipid bilayer or bicelle samples are very useful for the structural studies of membrane proteins. However, to study these biological samples using solid-state NMR, a specific probe with high efficiency and high capability is required. In this paper, we describe the optimized design, construction, and efficiency of a 400 MHz wide-bore $^1H-^{15}N$ solid-state NMR probe with 5-mm solenoidal rf coil for high power, multi-pulse sequence experiments, such as 2D PISEMA or 2D SAMMY.

Feasibility Study on Electro Coagulation Flocculation for Microalgae Harvesting (수처리용 미세조류의 수확을 위한 전기응집기술의 적용)

  • Lee, Seok Min;Cho, Jae Hyung;Noh, Kyung Ho;Zhang, Shan;Hwang, Hyeon-Jeong;Nam, guisook;Hwang, Sun-Jin
    • Journal of Korean Society of Water and Wastewater
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    • v.29 no.6
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    • pp.643-649
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    • 2015
  • Although microalgae are considered as a promising feedstock for biofuels, cost-efficient harvesting of microalgae needs to be significantly improved. In this study, the use of electro coagulation as a more rapid flocculation method for harvesting a freshwater (Scenedesmus dimorphus) microalgae species was evaluated. The results showed that, electro coagulation was shown to be more efficient using an aluminum anode than using an iron anode. And optimum conditions of electro coagulation for harvesting Scenedesmus dimorphus were found. The optimum stirring speed was 100 rpm and optimum pH was 5. Furthermore, the current density which the fastest and highest recovery efficiency is achieved at $30A/m^2$, while the highest energy efficiency was achieved at $10A/m^2$. A the rapid and high recovery efficiency indicate that electro coagulation is a particularly attractive technology for harvesting microalgae.