• Title/Summary/Keyword: Center Loss

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Protein Intake Recommendation for Korean Older Adults to Prevent Sarcopenia: Expert Consensus by the Korean Geriatric Society and the Korean Nutrition Society

  • Jung, Hee-Won;Kim, Sun-Wook;Kim, Il-Young;Lim, Jae-Young;Park, Hyoung-Su;Song, Wook;Yoo, Hyung Joon;Jang, HakChul;Kim, Kirang;Park, Yongsoon;Park, Yoon Jung;Yang, Soo Jin;Lee, Hae-Jeung;Won, Chang Won
    • Annals of Geriatric Medicine and Research
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    • v.22 no.4
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    • pp.167-175
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    • 2018
  • Sarcopenia, a common clinical syndrome in older adults, is defined as decreased muscle mass, strength, and physical performance. Since sarcopenia is associated with the incidence of functional decline, falls, and even mortality in older adults, researchers and health care providers have been keen to accumulate clinical evidence to advocate the screening and prevention of sarcopenia progression in older adults. The factors that may accelerate the loss of muscle mass and function include chronic diseases, inactivity, and deficiency in appropriate nutritional support. Among these, nutritional support is considered an initial step to delay the progression of muscle wasting and improve physical performance in community-dwelling older adults. However, a nationwide study suggested that most Korean older adults do not consume sufficient dietary protein to maintain their muscle mass. Furthermore, considering age-associated anabolic resistance to dietary protein, higher protein intake should be emphasized in older adults than in younger people. To develop a dietary protein recommendation for older adults in Korea, we reviewed the relevant literature, including interventional studies from Korea. From these, we recommend that older adults consume at least 1.2 g of protein per kg of body weight per day (g/kg/day) to delay the progression of muscle wasting. The amount we recommend (1.2 g/kg/day) is 31.4% higher than the previously suggested recommended daily allowance (i.e., 0.91 g/kg/day) for the general population of Korea. Also, evidence to date suggests that the combination of exercise and nutritional support may enhance the beneficial effects of protein intake in older adults in Korea. We found that the current studies are insufficient to build population-based guidelines for older adults, and we call for further researches in Korea.

The First Report on Clinical Manifestation of Cryopyrin-Associated Periodic Syndrome in Korean Children

  • Kim, Kwang Yeon;Kim, Sae Yun;Park, Su Eun;Lee, Jina;Lee, Hyunju;Lee, Soyoung;Kim, Joong Gon
    • Pediatric Infection and Vaccine
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    • v.25 no.3
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    • pp.113-122
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    • 2018
  • Purpose: The aim of this study was to evaluate the clinical characteristics of children diagnosed as cryopyrin-associated periodic syndrome (CAPS) in Korea. Methods: Diagnosis was made based on clinical features and confirmed by a mutation in the cold-induced autoinflammatory syndrome 1 (CIAS1) gene. Especially, osteocartilaginous overgrowth in the patella or distal femur was so characteristic that its presence warranted a diagnosis of chronic infantile neurologic cutaneous and articular/NOMID. Results: We observed the clinical features of 9 Korean CAPS patients. All the patients suffered from an urticarial rash with recurrent fever. Among the 9 patients, 6 presented with rash and 4 with fever on the 1st or 2nd days of birth. Eight patients showed myalgia, and 7 patients showed arthralgia in the joints, and 6 patients showed radiologic findings of arthropathy including cupping of the metaphysis, excessive growth of the epiphysis, osteopenia or overgrowth of the cartilage. Four patients showed brain atrophy, enlarged ventricles or leptomeningeal enhancement on magnetic resonance imaging. Intellectual disability was observed in 1 patient. Five patients had eye involvement as conjunctivitis, uveitis, chorioretinitis, avascular area or papillary edema, and 3 patients showed progressive hearing loss. All 9 patients showed increased C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). Conclusions: All the patients carried a mutation on exon 3 of the CIAS1 gene. After the anakinra (interleukin-1 receptor antagonist) therapy, the fever and rash immediately disappeared, and CRP and ESR were improved.

Cellular Automata Simulation System for Emergency Response to the Dispersion of Accidental Chemical Releases (사고로 인한 유해화학물질 누출확산의 대응을 위한 Cellular Automata기반의 시뮬레이션 시스템)

  • Shin, Insup Paul;Kim, Chang Won;Kwak, Dongho;Yoon, En Sup;Kim, Tae-Ok
    • Journal of the Korean Institute of Gas
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    • v.22 no.6
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    • pp.136-143
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    • 2018
  • Cellular automata have been applied to simulations in many fields such as astrophysics, social phenomena, fire spread, and evacuation. Using cellular automata, this study develops a model for consequence analysis of the dispersion of hazardous chemicals, which is required for risk assessments of and emergency responses for frequent chemical accidents. Unlike in cases of detailed plant safety design, real-time accident responses require fast and iterative calculations to reduce the uncertainty of the distribution of damage within the affected area. EPA ALOHA and KORA of National Institute of Chemical Safety have been popular choices for these analyses. However, this study proposes an initiative to supplement the model and code continuously and is different in its development of free software, specialized for small and medium enterprises. Compared to the full-scale computational fluid dynamics (CFD), which requires large amounts of computation time, the relative accuracy loss is compromised, and the convenience of the general user is improved. Using Python open-source libraries as well as meteorological information linkage, it is made possible to expand and update the functions continuously. Users can easily obtain the results by simply inputting the layout of the plant and the materials used. Accuracy is verified against full-scale CFD simulations, and it will be distributed as open source software, supporting GPU-accelerated computing for fast computation.

Qualitative Case Study on Psychological Difficulties Found In Each Divorce Decision Making Stage That Senescent Women Face in Their Early Stage of Elderly Life (초기노년기 여성이 경험한 이혼결정단계별 심리적 어려움에 관한 질적사례연구)

  • Moon, Jung Hwa;Kim, Mi Ra
    • Korean Journal of Family Social Work
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    • no.58
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    • pp.67-96
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    • 2017
  • The purpose of this study is to examine psychological difficulties that elderly women experience in each divorce decision making stage and they are shown by counselling cases made with elderly women who got divorced in their early stage of elderly life. For this purpose, total 18 counseling cases were collected from November 2012 to March 2013 and a qualitative analysis was made accordingly. The result of this study was made by analyzing meaningful subjects emerged in individual testimonies during a counseling process and it shows that the decision to divorce goes through stages such as , , , , , and . In addition, psychological difficulties experienced in a divorce decision process appear to be, , , , , , and . It is meaningful that this study provides counseling strategies for psychosocial support of the elderly women who go through difficulties in their divorce decision making process.

A Clinical Study for the Efficacy and Safety of Functional Cosmetics Containing peptide Scolopendrasin-I isolated from the Scolopendra subspinipes mutilans in Patients with Dry Skin due to Mild Atopic Dermatitis (아토피성 피부로 건조함을 가진 대상자에 대한 왕지네로부터 분리한 펩타이드 Scolopendrasin-I 함유 기능성 화장품의 기능성 및 안전성을 평가하기 위한 임상적 연구)

  • Park, Hye-Su;Kim, Tae-Jun;Park, Shin-Yong;Kim, Hee-Taek
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.32 no.3
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    • pp.23-36
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    • 2019
  • Objectives : The purpose of this study is to confirm the efficacy and safety of "Functional cosmetics containing peptide Scolopendrasin-I isolated from the Scolopendra subspinipes mutilans" on dry skin due to mild atopic dermatitis. Methods : A total of 24 patients who visited Semyung Oriental Medical Center from November 1st, 2018 to December 20th, 2018 were included in the study. In this study, the patients were treated with Functional cosmetics containing peptide Scolopendrasin-I isolated from the Scolopendra subspinipes mutilans. For 4 weeks of gross examination, instrumental assessment were made before and after the study to evaluate how well the products for treatment group in recovering the dry skin barriers by mild atopic dermatitis. Results : 1. In the primary endpoint, Skin Hydration showed a statistically significant increase in treatment group in baseline, 2 weeks and 4 weeks. 2. In the primary endpoint, Transepidermal Water Loss(TEWL) showed a statistically significant decrease in treatment group between Baseline and 4 weeks. 3. In the secondary endpoint, Skin pH showed a statistically significant decrease in treatment group between baseline and 4 weeks. 4. To evaluate the safety of the products for the human body, Adverse events, SCORAD Index Assessment were conducted; There were no severe adverse events during this study. And SCORAD Index showed a statistically significant decrease in treatment group in baseline, 2 weeks and 4 weeks. Therefore, it is suggested that products, if used for certain period, should be safe for the human body. Conclusions : According to the above experiments, it is suggested that "Functional cosmetics containing peptide Scolopendrasin-I isolated from the Scolopendra subspinipes mutilans" should be effective for dry skin due to mild atopic dermatitis.

Research of Monitoring of Conservation Condition and Investigation Method of National Designated Heritage - Focusing on Regular Monitoring of National Designated Movable Cultural Heritage - (국가지정 지류문화재의 보존현황 파악 및 조사방안 연구 - 국가지정 동산문화재 정기조사를 중심으로 -)

  • Jeong, Seon-Hwa;Park, Sang-Kyu
    • Korean Journal of Heritage: History & Science
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    • v.49 no.4
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    • pp.196-217
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    • 2016
  • This study was conducted to identify the state of conservation of the national paper heritages and to seek ways of conservation management, focusing on regular monitoring directly performed by the government on the national movable cultural heritages. Subjects for the investigation were limited to investigations conducted by both the Cultural Heritage Conservation Center and the Artistic Heritage Division in 2014 and 2015. Paper heritages are easily affected by temperature, humidity, lighting, etc. due to the nature of the material and can easily be damaged by physical strength; therefore stable conservation environment is essential and regular investigation on movable cultural heritages conducted according to the Cultural Heritage Protection Act is necessary to protect from contamination, being torn, bending, friction, or loss. Losing a chance for timely proper treatment will bring irrevocable result therefore strict management is necessary; continuous monitoring is also needed after treatment. Analysis on the pigments, materials and structures, detailed investigation, data establishment for conservation of cultural heritages and regular investigation should be done. Detailed data on the national cultural heritages will be a base of more reasonable conservation management system for the national paper heritages and will realize continuous improvement on regular investigation practice.

A Method for 3D Human Pose Estimation based on 2D Keypoint Detection using RGB-D information (RGB-D 정보를 이용한 2차원 키포인트 탐지 기반 3차원 인간 자세 추정 방법)

  • Park, Seohee;Ji, Myunggeun;Chun, Junchul
    • Journal of Internet Computing and Services
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    • v.19 no.6
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    • pp.41-51
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    • 2018
  • Recently, in the field of video surveillance, deep learning based learning method is applied to intelligent video surveillance system, and various events such as crime, fire, and abnormal phenomenon can be robustly detected. However, since occlusion occurs due to the loss of 3d information generated by projecting the 3d real-world in 2d image, it is need to consider the occlusion problem in order to accurately detect the object and to estimate the pose. Therefore, in this paper, we detect moving objects by solving the occlusion problem of object detection process by adding depth information to existing RGB information. Then, using the convolution neural network in the detected region, the positions of the 14 keypoints of the human joint region can be predicted. Finally, in order to solve the self-occlusion problem occurring in the pose estimation process, the method for 3d human pose estimation is described by extending the range of estimation to the 3d space using the predicted result of 2d keypoint and the deep neural network. In the future, the result of 2d and 3d pose estimation of this research can be used as easy data for future human behavior recognition and contribute to the development of industrial technology.

Comparison of Single-Incision Robotic Cholecystectomy, Single-Incision Laparoscopic Cholecystectomy and 3-Port Laparoscopic Cholecystectomy - Postoperative Pain, Cosmetic Outcome and Surgeon's Workload

  • Kim, Hyeong Seok;Han, Youngmin;Kang, Jae Seung;Lee, Doo-ho;Kim, Jae Ri;Kwon, Wooil;Kim, Sun-Whe;Jang, Jin-Young
    • Journal of Minimally Invasive Surgery
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    • v.21 no.4
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    • pp.168-176
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    • 2018
  • Purpose: Robotic-associated minimally invasive surgery is a novel method for overcoming some limitations of laparoscopic surgery. This study aimed to evaluate the outcomes (postoperative pain, cosmesis, surgeon's workload) of single-incision robotic cholecystectomy (SIRC) vs. single-incision laparoscopic cholecystectomy (SILC) vs. conventional three-port laparoscopic cholecystectomy (3PLC). Methods: 134 patients who underwent laparoscopic or robotic cholecystectomy at a single center during 2016~2017 were enrolled. Prospectively collected data included demographics, operative outcomes, questionnaire regarding pain and cosmesis, and NASA-Task Load Index (NASA-TLX) scores for surgeon's workload. Results: 55 patients underwent SIRC, 29 SILC, and 50 3PLC during the same period. 3PLC patient group was older than the others (SIRC vs. SILC vs. 3PLC: 48.1 vs. 42.2 vs. 54.1 years, p<0.001). Operative time was shortest with 3PLC (44.1 vs. 38.8 vs. 25.4 min, p<0.001). Estimated blood loss, postoperative complications, and postoperative stay were similar among the groups. Pain control was lowest in the 3PLC group (98.2% vs. 100% vs. 84.0%, p=0.004), however, at 2 weeks postoperatively there were no differences among the groups (p=0.374). Cosmesis scores were also worst after 3PLC (17.5 vs. 18.4 vs. 13.3, p<0.001). NASA-TLX score was highest in the SILC group (21.9 vs. 44.3 vs. 25.2, p<0.001). Conclusion: Although SIRC and SILC take longer than 3PLC, they produce superior cosmetic outcomes. Compared with SILC, SIRC is more ergonomic, lowering the surgeon's workload. Despite of higher cost, SIRC could be an alternative for treating gallbladder disease in selected patients.

Soil Carbon Storage in Upland Soils by Biochar Application in East Asia: Review and Data Analysis (바이오차를 이용한 밭 토양 탄소 저장: 동아시아 지역 연구 리뷰 및 데이터 분석)

  • Lee, Sun-Il;Kang, Seong-Soo;Choi, Eun-Jung;Gwon, Hyo-Suk;Lee, Hyoung-Seok;Lee, Jong-Mun;Lim, Sang-Sun;Choi, Woo-Jung
    • Korean Journal of Environmental Agriculture
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    • v.40 no.3
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    • pp.219-230
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    • 2021
  • BACKGROUND: Biochar is a solid material converted from agricultural biomass such as crop residues and pruning branch through pyrolysis under limited oxygen supply. Biochar consists of non-degradable carbon (C) double bonds and aromatic ring that are not readily broken down by microbial degradation in the soils. Due to the recalcitrancy of C in biochar, biochar application to the soils is of help in enhancing soil carbon sequestration in arable lands that might be a strategy of agricultural sector to mitigate climate change. METHODS AND RESULTS: Data were collected from studies on the effect of biochar application on soil C content conducted in East Asian countries including China, Japan and Korea under different experimental conditions (incubation, column, pot, and field). The magnitude of soil C storage was positively correlated (p < 0.001) with biochar application rate under field conditions, reflecting accumulation of recalcitrant black C in the biochar. However, The changes in soil C contents per C input from biochar (% per t/ha) were 6.80 in field condition, and 12.58 in laboratory condition. The magnitude of increment of soil C was lower in field than in laboratory conditions due to potential loss of C through weathering of biochar under field conditions. Biochar production condition also affected soil C increment; more C increment was found with biochar produced at a high temperature (over 450℃). CONCLUSION: This review suggests that biochar application is a potential measures of C sequestration in agricultural soils. However, as the increment of soil C biochar was affected by biochar types, further studies are necessary to find better biochar types for enhanced soil C storage.

Impact of piezocision on orthodontic tooth movement

  • Papadopoulos, Nikolaos;Beindorff, Nicola;Hoffmann, Stefan;Jost-Brinkmann, Paul-Georg;Prager, Thomas Michael
    • The korean journal of orthodontics
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    • v.51 no.6
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    • pp.366-374
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    • 2021
  • Objective: This study investigated the impact of a single piezocision in the maxillary alveolar process on the speed of tooth movement. The null hypothesis was that the speed of tooth movement will be equal with and without piezocision. Methods: All maxillary molars on one side were moved against the combined incisors in 10 ten-week-old male Wistar rats. Under general anesthesia, a force of 25 cN was applied on either side using a Sentalloy closed coil spring. After placing the orthodontic appliance, vertical corticision was performed using a piezotome under local anesthesia, 2 mm mesial from the mesial root of the first molar on a randomly selected side; the other side served as the control. At the beginning of the treatment, and 2 and 4 weeks later, skull micro-computed tomography was performed. After image reconstruction, the distance between the mesial root of the first molar and the incisive canal, and the length of the mesial root of the first maxillary molar were measured. Moreover, the root resorption score was determined as described by Lu et al. Results: Significantly higher speed of tooth movement was observed on the corticision side; thus, the null hypothesis was rejected. The loss of root length and root resorption score were significantly more pronounced after piezocision than before. A strong correlation was observed between the speed of tooth movement and root resorption on the surgical side, but the control side only showed a weak correlation. Conclusions: Piezocision accelerates orthodontic tooth movement and causes increased root resorption.