• 대한생식의학회:학술대회논문집
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• 2006.11a
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• pp.122-123
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• 2006

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2009.04a
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• pp.239-239
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• 2009

• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2004.05a
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• pp.63-63
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• 2004

• 대한생식의학회:학술대회논문집
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• 2003.12a
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• pp.146.1-146.1
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• 2003

• Clinical and Experimental Reproductive Medicine
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• v.40 no.4
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• pp.174-176
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• 2013

Klinefelter syndrome is the most common genetic form of male hypogonadism, but the phenotype becomes evident only after puberty. It is characterized by infertility, small testes, sparse body and facial hair, increased body weight, gynecomastia, increased LH and FSH, and a low level of testosterone. Early recognition and treatment of Klinefelter syndrome can significantly improve the patient's quality of life and prevent serious consequences. Here, we report an infertile man with a rare variant of Klinefelter syndrome with a 47, XY, i(X)(q10) karyotype.

• 대한두경부종양학회:학술대회논문집
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• 2007.11a
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• pp.210-210
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• 2007

• Journal for History of Mathematics
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• v.34 no.4
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• pp.137-149
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• 2021

The center of gravity of a triangle is the center of a physical shape. This is the content in the second grade of middle school, 'The Use of Similarity'. Unlike the cases of circumcenter and incenter, which are easily recognized visually, it is not easy for teachers to guide students with the visual meaning of center of gravity. According to the survey results, students, regardless of academic achievement, grade, and major, perceived the center of gravity of various plane figure as the center of their shape within a limited area through visual judgment. With reference to the results and contents of this process, it is hoped that the point of the three medians is meaningful not only in argumentative definition that the intersection of the triple line is the center of gravity of the triangle, but also in the center of a figure.

• Bioinformatics and Biosystems
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• v.1 no.1
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• pp.28-37
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• 2006

Recent studies in molecular biology and proteomics have identified a significant number of novel diagnostic, prognostic, and therapeutic disease markers. However, validation of these markers in clinical specimens with traditional histopathological techniques involves low throughput and is time consuming and labor intensive. Tissue microarrays (TMAs) offer a means of combining tens to hundreds of specimens of tissue onto a single slide for simultaneous analysis. This capability is particularly pertinent in the field of cancer for target verification of data obtained from cDNA micro arrays and protein expression profiling of tissues, as well as in epidemiology-based investigations using histochemical/immunohistochemical staining or in situ hybridization. In combination with automated image analysis, TMA technology can be used in the global cellular network analysis of tissues. In particular, this potential has generated much excitement in cardiovascular disease research. The following review discusses recent advances in the construction and application of TMAs and the opportunity for developing novel, highly sensitive diagnostic tools for the early detection of cardiovascular disease.

• Korean Journal of Veterinary Research
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• v.48 no.4
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• pp.401-411
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• 2008

This study was performed to evaluate repeated-dose oral toxicities of Flos lonicerae extract in Fischer 344/n rats. Flos lonicerae was administered orally to rats at dose levels of 0, 37, 111, 333, 1,000 and 2,000 mg/kg/day. Each group consisted of 10 rats of each gender. The Flos lonicerae extract was given once a day, 5 times a week, for 90 day repeatedly. This study was conducted in accordance with the Protocol of Korea National Toxicology Program and The Standards of Toxicity Study for Medicinal Products. In the present study, there were no toxicologically significant changes in mortality, clinical signs, body weight gains, ophthalmoscopy, urine analysis, hematology, serum biochemistry, necropsy findings, organ weights, histopathology, estrus cycle and sperm examination of all animals treated with Flos lonicerae extract. These results suggest that the oral no observed adverse-effect level of the test item, Flos lonicerae extract, in rats is higher than 2,000 mg/kg/day in both genders. The target organs were not established.

• Journal of Korean Traditional Oncology
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• v.15 no.1
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• pp.71-77
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• 2010

This case report documents a case in which the administration of an herbal product, an extract of the lacquer tree, Rhus verniciflua Stokes was related with a prolonged survival in a elderly advanced non-small cell lung cancer(NSCLC) patient. A 79-year-old man who had been diagnosed with advanced NSCLC refused conventional therapy and treatment with the allergen-removed Rhus verniciflua Stokes(aRVS) had continued from September 2007 to July 2010. He had survived for 35 months after the administration of aRVS and maintained good performance status with European Cooperative Oncology Group performance status(ECOG PS) of 1. This case suggests that aRVS be alternative treatment for the elderly advanced NSCLC patients.