• ETRI Journal
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• 제28권3호
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• pp.282-290
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• 2006

In vertically overlaid cellular systems, a temporary traffic concentration can occur in a hot-spot area, and this adversely affects overall system capacity. In this paper, we develop an adaptive hot-spot operating scheme (AHOS) to mitigate the negative effects from the nonuniform distribution of user location and the variation in the mixture of QoS requirements in orthogonal frequency division multiple access downlink systems. Here, the base station in a macrocell can control the operation of picocells within the cell, and turns them on or off according to the system overload estimation function. In order to determine whether the set of picocells is turned on or off, we define an AHOS gain index that describes the number of subcarriers saved to the macrocell by turning a specific picocell on. For initiating the picocell OFF procedure, we utilize the changes in traffic concentration and co-channel interference to the neighboring cells. According to computer simulation, the AHOS has been proved to have maximize system throughput while maintaining a very low QoS outage probability under various system scenarios in both a single-cell and multi-cell environments.

• ETRI Journal
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• 제42권5호
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• pp.712-720
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• 2020

Recently, to make the best use of limited and precious spectrum resources, spectrum sharing between satellite and cellular networks has received much interest. In this study, we mathematically analyze the success probability of a fixed (satellite) earth station (FES) based on a stochastic geometry framework. Both the FES and base stations (BSs) are assumed to be equipped with a directional antenna, and the location and the number of BSs are modeled based on the Poisson point process. Furthermore, an exclusion zone is considered, in which the BSs are prohibited from locating in a circular zone with a certain radius around the FES to protect it from severe interference from the cellular BSs. We validate the analytical results on the success probability of the cognitive satellite-terrestrial network with directional antennas by comparing it using extensive computer simulations and show the effect of the exclusion zone on the success probability at the FES. It is shown that the exclusion zone-based interference mitigation technique significantly improves the success probability as the exclusion zone increases.

• Molecules and Cells
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• 제27권4호
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• pp.391-396
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• 2009

Image-based, high-content screening assays demand solutions for image segmentation and cellular compartment encoding to track critical events - for example those reported by GFP fusions within mitosis, signalling pathways and protein translocations. To meet this need, a series of nuclear/cytoplasmic discriminating probes have been developed: DRAQ5$^{TM}$ and CyTRAK Orange$^{TM}$. These are spectrally compatible with GFP reporters offering new solutions in imaging and cytometry. At their most fundamental they provide a convenient fluorescent emission signature which is spectrally separated from the commonly used reporter proteins (e.g. eGFP, YFP, mRFP) and fluorescent tags such as Alexafluor 488, fluorescein and Cy2. Additionally, they do not excite in the UV and thus avoid the complications of compound UV-autofluorescence in drug discovery whilst limiting the impact of background sample autofluorescence. They provide a convenient means of stoichiometrically labelling cell nuclei in live cells without the aid of DMSO and can equally be used for fixed cells. Further developments have permitted the simultaneous and differential labelling of both nuclear and cytoplasmic compartments in live and fixed cells to clearly render the precise location of cell boundaries which may be beneficial for quantitative expression measurements, cell-cell interactions and most recently compound in vitro toxicology testing.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제17권9호
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• pp.2590-2608
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• 2023

The high-altitude and mobility characteristics of unmanned aerial vehicles (UAVs) have made them a key element of new radio systems, particularly because they can exceed the limits of terrestrial networks. However, at high altitudes, UAVs can be significantly affected by intercell interference at a high line-of-sight probability. To mitigate this drawback, we propose an algorithm that selects the optimal beam to reduce interference and maximize transmission efficiency. The proposed algorithm comprises two steps: constructing a user-location-based fingerprint database according to the user types presented herein and cooperative beam selection. Simulations were conducted using cellular cooperative downlink systems for analyzing the performance of the proposed method, and the signal-to-interference-plus-noise cumulative distribution function and spectral efficiency cumulative distribution function were used as performance analysis indicators. Simulation results showed that the proposed algorithm could reduce the effect of interference and increase the performance of the desired signal. Moreover, the algorithm could efficiently reduce overheads and system cost by reducing the amount of resources required for information exchange.

• IMMUNE NETWORK
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• 제21권1호
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• pp.3.1-3.16
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• 2021

Coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been spreading worldwide since its outbreak in December 2019, and World Health Organization declared it as a pandemic on March 11, 2020. SARS-CoV-2 is highly contagious and is transmitted through airway epithelial cells as the first gateway. SARS-CoV-2 is detected by nasopharyngeal or oropharyngeal swab samples, and the viral load is significantly high in the upper respiratory tract. The host cellular receptors in airway epithelial cells, including angiotensin-converting enzyme 2 and transmembrane serine protease 2, have been identified by single-cell RNA sequencing or immunostaining. The expression levels of these molecules vary by type, function, and location of airway epithelial cells, such as ciliated cells, secretory cells, olfactory epithelial cells, and alveolar epithelial cells, as well as differ from host to host depending on age, sex, or comorbid diseases. Infected airway epithelial cells by SARS-CoV-2 in ex vivo experiments produce chemokines and cytokines to recruit inflammatory cells to target organs. Same as other viral infections, IFN signaling is a critical pathway for host defense. Various studies are underway to confirm the pathophysiological mechanisms of SARS-CoV-2 infection. Herein, we review cellular entry, host-viral interactions, immune responses to SARS-CoV-2 in airway epithelial cells. We also discuss therapeutic options related to epithelial immune reactions to SARS-CoV-2.

• 한국통신학회논문지
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• 제18권10호
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• pp.1553-1571
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• 1993

전형적인 컬퓨터보다 훨씬 강력한 계산 능력을 얻기 위해 병렬 컴퓨터 구조에 대한 많은 연가 진행되어 왔다. 이러한 컴퓨터들은 통상 상호 연결 네트워크(Interconnection Network)로 연결된 많은 수의 처리기들로 구성된다. 그중 중요한 한 부류가 초대규모 집적(Very Large Scale Integration) 또는 웨이퍼규모 집적(Wafer Scale Integration)을 이용한 셀룰러 병렬 처리기로 하나의 칩이나 웨이퍼에 단지 이웃으로만 연결된 많은 수의 단순 조를 가지는 처리기로 구성된다. 이런 셀룰러 병렬 처리기틀에 반드시 수반되는 문제가 재구현(Reconfiguration)으로 세가지 유형을 정의할 수 있는데 본 논문에서는 이 세가지 재구현 문제, 즉 결함 허용 재구현(Fault-Tolerant Reconfiguration), 기능적 재구현(Functional Reconfiguration), 그리고 통합 재구현(Integrated Reconfiguration)에 대하여 논하였다. 본 논문은 결함 진단 및 검출(Fault Detection and Fault Location) 제어 방법, 구성(Configuration) 제어방법, 재구현의 수행 단계 등 결함 허용 재구현과 기능적 재구현시 필요한 여러 고려 사항을 분석 정리하고, 최근 제기된 결함 허용 재구현과 기능적 재구현의 일체화 문제 즉 통합 재구현 문제의 이해에 핵심적인 결할 허용 재구현과 기능적 재구현 사이의 관계를 밝혔으며, 통합 재 구현에 적합한 결할 진단 및 검출 제어 방법과 구성제어 방법에 대하여 논하였다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2007년도 추계종합학술대회
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• pp.482-485
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• 2007

무선컴퓨팅에서의 최근 동향은 모바일능력을 향상시키고, 응용범위의 필요성에 적합한 새로운 접근 방법을 개발하는데 초점이 모아지고 있다. 이 논문은 환자의 무선의료 소자로부터 무선으로 데이터를 받고 반응하고 그 셀룰러 네트워크를 활용하여 의료센터로 보내는 기능을 가진 IEEE802.15.4 무선 CDMA기반의 헬스케어 시스템에 관한 것이다. 모바일 응용시스템은 무선센서네트워크와 셀룰러 네트워크사이에서 의료데이터를 받고 보내는 것을 조절하는 미들웨어 뿐만 아니라 위치에 상관없이 휴대전화로 환자의 헬스상태를 연속적으로 모니터링하고 분석하는 인터페이스를 제공한다. 따라서 이 시스템은 원격 헬스모니터링을 가능하게 하고 IEEE802.15.4 무선네트워크와 병원이외의 지역에서의 CDMA 네트워크사이에서 원격 헬스모니터링과 끊김없는 메디컬데이터 연결을 제공한다.

• Spatial Information Research
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• 제16권2호
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• pp.157-171
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• 2008

최근에는 대형건축물, 지하철과 같은 대규모 실내공간에서의 화재와 같은 사고에 대한 인식이 확대되고 있다. 그러나 현재까지는 그에 대한 적절한 서비스, 설계, 평가 방법이 미약한 실정이며 관련 연구들도 학술적 연구차원이거나 가상의 시뮬레이터 중심인 경우가 대부분이다. 최근 유비쿼터스 관련 분야에 대한 관심과 함께 실내 위치측위기술 역시 발전하고 있는데, 이러한 기술을 이용할 경우, 방재분야 역시 단순 시뮬레이터에서 실시간 대피 안내시스템으로 확대시킬 수 있는 가능성이 있다. 그러나 현재 개발되어있는 대피 시뮬레이션의 경우에는 지리참조 되지 않은 건축도면을 기반으로 구축되어 있어서 이러한 실내 센서와 연동하기에는 한계가 있다. 본 연구에서는 이러한 실내 위치기반 실시간 방재시스템으로의 확대를 위한 기초연구로서, 데이터 구조 및 대피경로 산출 방법을 제시하고 이를 적용하여 대피시뮬레이션 테스트를 실시하였다. 좌표계가 적용된 GIS 데이터를 활용하는 방안을 제시하였고, 실내 이동자의 움직임을 나타내는 데에는 Cellular Automata(CA) 모델을 적용하였다.

• 농촌계획
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• 제9권4호
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• pp.43-51
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• 2003

This study aims to integrate the simulation models for rural settlement planning (SimRusep) in the district level (Myon) area of rural counties. The SimRusep, which has two modules of key villages selection and spatial planning for the selected villages, consists of four sub-models such as the spatial location-allocation model of center villages (SLAMCV), the potential centrality evaluation model (PCEM), the land use planning model (LUPM), and the 3-dimensional spatial planning modeller (3DSPLAM). Basically, map data of the integrated system which can be operated on the UNIX environment is inputted and treated using GIS (ARC/INFO) and then its village planning results is graphically presented on the AutoCAD. In order to verify the practical applicabilities of the SimRusep, an administrative area, Ucheon-myun, HoengSung-gun, KangWon-do, was selected as a case study area. It was well operated in the strategic application trials considering application of each sub-model in the study area. The operation results of the SimRusep showed the possibilities of realtime simulation from the selection of key village to its final stereoscopic presentation of planned results. Alternative village plan proposals can be swiftly drafted, which means very practical support for decision making process and public participation.

• 융합신호처리학회논문지
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• 제7권1호
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• pp.24-32
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• 2006

본 논문에서는 무선 이동통신망에서 멀티미디어 응용 프로그램의 서비스 품질 보장을 위하여 무선 단말기의 이동성을 예측하기 위하여 무선 단말기 위치 예측에 기반을 둔 대역폭 예약 알고리즘을 제안한다. 제안된 알고리즘은 이동성 예측 기법을 이용하여 단말기의 이동 방향에 대한 예측 오류를 최소화하는 것을 목적으로 한다. 이러한 예측은 불필요하게 중복되어 예약된 대역폭의 크기를 줄인다. 알고리즘의 성능 평가를 위해서, 신규호의 탈락률과 핸드오프호의 강제종료율을 측정하고 기존에 제안된 기법들의 성능 평가 결과와 비교한다. 그 결과 본 논문에서 제시된 알고리즘이 기존의 방법들에 비해 낮은 호 탈락률 및 강제종료율을 가지는 우수한 성능을 나타내었다