• BMB Reports
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• 제48권10호
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• pp.583-588
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• 2015

Microtubule actin crosslinking factor 1 (MACF1), a widely expressed cytoskeletal linker, plays important roles in various cells by regulating cytoskeleton dynamics. However, its role in osteoblastic cells is not well understood. Based on our previous findings that the association of MACF1 with F-actin and microtubules in osteoblast-like cells was altered under magnetic force conditions, here, by adopting a stable MACF1-knockdown MC3T3-E1 osteoblastic cell line, we found that MACF1 knockdown induced large cells with a binuclear/multinuclear structure. Further, immunofluorescence staining showed disorganization of F-actin and microtubules in MACF1-knockdown cells. Cell counting revealed significant decrease of cell proliferation and cell cycle analysis showed an S phase cell cycle arrest in MACF1-knockdown cells. Moreover and interestingly, MACF1 knockdown showed a potential effect on cellular MTT reduction activity and mitochondrial content, suggesting an impact on cellular metabolic activity. These results together indicate an important role of MACF1 in regulating osteoblastic cell morphology and function.

• 천문학논총
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• 제22권3호
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• pp.75-81
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• 2007

In this study we present basic principles and features of RVI2CELL, a precise RV (radial velocity) estimation program to process stellar spectra obtained through iodine cell. RVI2CELL is very robust and fast program. The instrument profile can be modeled as a sum of Gaussian functions or a non-parametric arbitrary shape. The RV accuracy estimated by observation of a RV standard star Tau Ceti indicates about 9 m/s.

• Journal of Astronomy and Space Sciences
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• 제36권2호
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• pp.69-74
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• 2019

Spacecraft requires sufficient power in orbit to perform its mission. So as to comply with system requirements, the sufficient power should be made by a solar cell array by photovoltaic power conversion. A life time of space program depends on its mission considering parts reliability and parts grade. Based on the mission life time, power equipment might be designed to meet specifications. In outer space, solar cell array might generate the dc power by photovoltaic conversion effects and GaInP/GaAs/Ge solar cells are used in this study. Space programs that require more than five years should select parts for high reliability applications. Therefore, reliability analysis for high reliability applications should be performed to check its fulfilment of the requirements. This program should also require more five years for its mission and we performed its analysis using parts count method (PCM) for its reliability. Finally, we performed reliability analysis and obtained quantitative figures found out 99.9%. In this study, we presented the reliability analysis of the 300 W GaInP/GaAs/Ge solar cell array.

• 한국통신학회논문지
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• 제37A권12호
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• pp.1093-1105
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• 2012

본 논문에서는 3-Cell 간섭 환경에서의 하향링크 MU-MIMO를 위한 간섭 공간 재활용 기술 (ISR)과 그 적용방안을 제시한다. 멀티 셀 간섭환경의 셀 경계 사용자들의 안정적인 통신을 위해서는 효율적인 간섭 관리가 필요하다. 하지만 셀 중심부의 사용자들의 경우 간섭의 영향을 적게 받으며 적은 전송 전력으로도 안정적인 통신이 가능하다. 본 논문에서는 셀 경계 사용자의 간섭 공간을 재사용하여 셀 중심부 사용자에게 서비스를 제공하는 ISR 기반 전송 신호 설계 방법을 제시한다. ISR 방식은 간섭정렬(IA)과 결합된 부분적 주파수 재활용 (fractional frequency reuse : FFR) 방식과 비교하여 볼 때 셀 중심 사용자와 셀 경계 사용자에 대한 scheduling에 따라 전체 네트워크 데이터 전송용량 측면에서 20%의 성능 향상을 보이며 또한 셀 중심 사용자의 서비스 품질 (QoS) 요구조건이 고정되어 있는 경우 ISR 방식에 의해 기지국에서의 전송 신호 벡터를 설계함으로서 셀 경계 사용자의 데이터 전송 용량을 증가시킬 수 있다.

• 한국실내디자인학회논문집
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• 제20권5호
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• pp.23-33
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• 2011

Starting with 21st Century, the role of the design has been widened and designers began to regard the psychological and behavioral factors as main design considerations. These factors are the core elements especially in designing interactive space. This research proposed the user-centered design methodology for interactive space. It developed Programming Process for Supporting Interactive Behaviors. To compose the process, this research analyzed the influential factors on the interactivity and the results were applied on the process. This newly proposed Programming Process contains four basic stages which are 'Opportunity Identification Cell', 'Intersubject Cell', 'Interaction & Interface Cell', and 'Programming Solution Cell'. More detailed tasks are also specified for each stage. This research asserts that the design process for Interactive space should differ from the past design processes in the fact that it puts much more attention on systemizing the psychological and behavioral elements than before. Therefore the design process for Interactive space should be reinforced with the data related to these psychological and behavioral understandings. The Programming Process of this paper is an attempt to enlarge the roles of these data in designing interactive space, and thus it is an attempt to accommodate the contemporary user-centered design paradigm.

• Journal of Astronomy and Space Sciences
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• 제32권1호
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• pp.81-89
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• 2015

In this paper, we describe the development of a bioreactor for a cell-culture experiment on the International Space Station (ISS). The bioreactor is an experimental device for culturing mouse muscle cells in a microgravity environment. The purpose of the experiment was to assess the impact of microgravity on the muscles to address the possibility of long-term human residence in space. After investigation of previously developed bioreactors, and analysis of the requirements for microgravity cell culture experiments, a bioreactor design is herein proposed that is able to automatically culture 32 samples simultaneously. This reactor design is capable of automatic control of temperature, humidity, and culture-medium injection rate; and satisfies the interface requirements of the ISS. Since bioreactors are vulnerable to cell contamination, the medium-circulation modules were designed to be a completely replaceable, in order to reuse the bioreactor after each experiment. The bioreactor control system is designed to circulate culture media to 32 culture chambers at a maximum speed of 1 ml/min, to maintain the temperature of the reactor at $36{\pm}1^{\circ}C$, and to keep the relative humidity of the reactor above 70%. Because bubbles in the culture media negatively affect cell culture, a de-bubbler unit was provided to eliminate such bubbles. A working model of the reactor was built according to the new design, to verify its performance, and was used to perform a cell culture experiment that confirmed the feasibility of this device.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2008년도 한국우주과학회보 제17권2호
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• pp.33.3-34
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• 2008

As an activity of building Korean Space Weather Prediction Center (KSWPC), we has studied of radiation effect on the spacecraft components. High energy charged particles trapped by geomagnetic field in the region named Van Allen Belt can move to low altitude along magnetic field and threaten even low altitude spacecraft. Space Radiation can cause equipment failures and on occasions can even destroy operations of satellites in orbit. Sun sensors aboard Science and Technology Satellite (STSAT-1) was designed to detect sun light with silicon solar cells which performance was degraded during satellite operation. In this study, we try to identify which particle contribute to the solar cell degradation with ground based radiation facilities. We measured the short circuit current after bombarding electrons and protons on the solar cells same as STSAT-1 sun sensors. Also we estimated particle flux on the STSAT-1 orbit with analyzing NOAA POES particle data. Our result clearly shows STSAT-1 solar cell degradation was caused by energetic protons which energy is about 700 keV to 1.5 MeV. Our result can be applied to estimate solar cell conditions of other satellites.

• 한국항공우주학회지
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• 제37권10호
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• pp.1017-1026
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• 2009

우주비행체의 주 전력원인 태양전지 시스템은 태양광을 직접 바라본 상태에서 운용되어, 우주의 가혹한 열적/기계적 환경에 직접 노출되므로, 제작/시험 중 발생될 수 있는 미세한 균열, 정전기 및 열 충격 등이 궤도 운용 중 태양전지 시스템의 기능상실로 이어질 가능성을 갖는다. 또한 태양전지 시스템의 전력생성 기본 유닛인 태양전지에 발생된 미세한 균열 또는 열 충격에 따른 태양전지의 내부 파손의 발견을 위해서는 고가의 장비와 복잡한 시험 절차, 그리고 많은 시간을 필요로 하게 된다. 따라서 태양전지 시스템 기능의 건전성을 쉽고, 빠르게 확인하기 위해, 정성적인 태양전지 기능 건전성 평가 방법이 요구된다. 본 논문에서는 요즘 우주비행체에서 가장 많이 사용되는 갈륨-비소 계열의 다접합 태양전지가 갖는 전계발광현상을 이용해 복잡한 반도체 구조를 가지는 태양전지의 기능 건전성을 보다 간단하고 저비용으로 그리고 빠르게 평가하는 방법에 대한 이론적, 기술적 근거를 설명하였다. 또한 이를 실제의 우주용 태양전지 시스템에 적용하기 위한 기술적 사항들과 적용 제한 조건들에 대하여 기술하였다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제50권1호
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• pp.56-59
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• 2024

There are very few case reports of the diagnosis and management of concurrent oral cavity and parapharyngeal space tumors. We present a case involving a 49-year-old female who presented with oral cavity squamous cell carcinoma confirmed by biopsy. Initial diagnostic workup revealed a concurrent parapharyngeal mass. Diagnostic studies and surgical therapy were tailored to account for both pathological entities. The patient was treated with a combination of surgery and adjuvant therapy. The surgical strategy was designed to address both lesions simultaneously. One year post-surgery, the patient had good response to therapy with no evidence of persistent or recurrent disease. This report discusses the outcome and treatment of a rare case of concurrent squamous cell carcinoma with a complicating parapharyngeal space tumor. It explores the diagnostic process, comprehensive workup, and the surgical management.

• 한국실내디자인학회논문집
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• 제34호
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• pp.106-113
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• 2002

Certosa, a representative Monastic Architecture of Renaissance era, has been well preserved. And it has worked as a symbol of the space form & style revealed by monad, sell, arcade and court, which are characteristic of a monastery. A court is divided into large court and small one, and it connects each units and each sells through the annex with clarifying each space identities. And arcade and pillar is not only to derive a unitary space from entire space, but also to try openness and extension applying a different height in spite of physical closure of style. Especially planned by monad and cell, the routine space of monks, a structure of rational space is a yardstick of moderation and frugality, showing affluent space which occupy essential areas without extra space. And the space appears self-sufficiency, honest poverty, and affluence with order and eternity based on elementary principles of the Cartusio order in composition and plan of the space. Keeping strong linking with entire sells in the monastery, Each sell symbolizes entire sells, and the inverse is the same. And it is the universe advocating eternity and it is also a small city which provides the monks with accurate modules and scales in the very recluse space.