• 동의생리병리학회지
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• 제26권1호
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• pp.40-46
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• 2012

Cigarette smoking is known to be associated with various chronic pulmonary and cardiovascular diseases ranging from inflammation to cancer. Not only first-hand smoke but also second-hand smoke is suggested to be a factor of health risk. This study was to investigate whether Platycodi Radix extract administration would alter oxidative stress in lung leading to protection of cigarette smoke-induced lung damage. Sprague-Dawley rats were randomly divided into 3 groups; Intact, Smoke+PR and Smoke+Vehicle. In Smoke+PR and Smoke+Vehicle group, the exposure to cigarette smoke was performed for 15 min/day for 4 weeks in ventilated smoking chamber. The Platycodi Radix extract and saline were orally administrated to Smoke+PR and Smoke+Vehicle group each. The rats of Intact group were just kept in ventilated chamber without cigarette smoke. After the experiment for 4 weeks, the lung tissues were collected for histological observation and immunohistochemistry. In Results, airspace enlargement and goblet cell hyperplasia were observed after 4 weeks' exposure to cigarette smoke. Whereas, the oral administration of Platycodi Radix extract for 4 weeks reduced airspace enlargement and goblet cell hyperplasia. Moreover, the alterations of BAX/Bcl-2 proteins in lung tissues were observed. These results suggest that Platycodi Radix extract ameliorates lung damage in cigarette smoke-exposed rats and has protective effects on second-hand smoke injury.

• Childhood Kidney Diseases
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• 제13권2호
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• pp.278-281
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• 2009

소아에서 혈액암의 경우 간비종대 없이 신장 비대만을 보이는 경우는 매우 드물다. 저자들은 한 달간 급속히 진행하는 복부 팽만을 주소로 병원에 온 9개월 된 남아에서, 간비종대가 없이 양측 거대신 소견만을 보이는 급성 림프구성 백혈병을 경험하였기에 그 임상상을 보고하는 바이다.

• 한국임상수의학회지
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• 제17권2호
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• pp.470-474
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• 2000

A Shih Tzu Puppy had clinical onset of anotexia crying and progression of neurological sings when enlargement of the cranial vault at 1 month old and died after showing clinical signs during 2 months period. Radiological and pathological examinations were performed. Radiological findings were homogeneous appearance of the calvaria with cortical thinning, loss of the normal convolutional skull markings and persistent fontanelles. Grossly enlargement of the cranial vault thinning of the bone and defective closure of the fontanelles were also observed. The entire subcortical area of the cerebral hemispheres with severe, dilatation of ventricles and cerebrospinal fluid(CSF) wits absent. There was parenchyma atrophy affecting chiefly in the white mater and the cerebral cortices, axon degeneration and necrosis and gitter cell infiltration in the whiter matter and the subependymal area. Mononuclear perivacular cuffing in the cerebrum and the pons was shown. Based on the radiological, gross and histopathological findings, this case was believed to have congenital hydrocephalus with nonsuppurative encephahitis. Possible etiology on the case is also discussed.

• 한국자원식물학회지
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• 제30권1호
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• pp.88-95
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• 2017

토양수분의 변화가 블랙쵸크베리 'Nero'의 과실 특성에 미치는 영향을 조사하여 고품질 블랙쵸크베리 재배 연구의 기초자료를 제공하고자 수행하였다. 토양수분 감소로 인한 건조스트레스는 수확기 동안 블랙쵸크베리의 과실의 과중, 당도, 안토시아닌 함량 등의 품질을 저하시켰다. 또한 건조기간이 길수록 이후 토양수분 공급시, 과실 표피 세포 크기는 감소하는 반면 아표피, 과육 세포의 크기가 증가하여 열과를 유발할 수 있다. 따라서 관수시설을 통한 일정 주기의 관수가 블랙쵸크베리 과실 생산량 및 품질 향상을 위해 필요할 것으로 생각된다.

• 한국동물위생학회지
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• 제36권2호
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• pp.127-132
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• 2013

An 11-year-old poodle bitch was presented for investigation of multicentric mammary masses. Abdominal sonography and radiography demonstrated abnormal enlargement of uterus and ovaries. Blood analysis revealed high progesterone concentration. The ovariohysterectomy and mastectomy were performed. Histopathologically, the mammary masses revealed complex carcinoma-tubulopapillary carcinoma with papillary pattern and tubule pattern. In the uterus, cystic endometrial hyperplasia was observed. Scattered inflammatory cells were observed in the endometrial stroma and mucinous material was protruded from endometrial surface. Also, in the ovaries, bilateral ovary granulosa cell tumor was detected. The bitch made a complete recovery following the ovariohysterectomy and mastectomy. This case was a very rare multiple tumor occurrence with bilateral ovary granulosa cell tumor and mammary complex carcinoma. High progesterone concentration was characterized clinically in the bitch.

• 한국생물물리학회:학술대회논문집
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• 한국생물물리학회 2001년도 학술 발표회 진행표 및 논문초록
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• pp.39-39
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• 2001

Many physiological processes of plant cells, such as nutrient uptake, salt tolerance, and cell enlargement, are mediated by ion transports across the plasma membrane. H$^{＋}$-ATPases on both plasma and vacuolar membranes play major roles on active transports and ion channels mediate passive transports of various ions. It has been known that these proteins involved in cellular osmotic regulation and salt tolerance in the salt-accumulated soils.(omitted)

• Applied Microscopy
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• 제5권1호
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• pp.21-30
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• 1975

To investigate ultrastructural characteristics of cancer cell nucleus, 29 cases of malignant tumors of 9 different types were examined. The common findings were marked irregularity of nuclear membrane with pronounced infoldings, clumping of heterochromatin along inner nuclear membrane, enlargement and disturbance of configuration and composition of nucleolus, and frequent observations of nuclear bodies and nuclear inclusions. These findings confirm what have been observed by light microscopy, and are also the signes that can be observed in hyperactive cells. Thus, ultrastructural characteristics of cancerous nucleus are the great variability of nuclear size, shape and composition, but none of them appear to be specific.

• 한국전자파학회논문지
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• 제15권4호
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• pp.387-396
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• 2004

음성과 데이터를 동시에 다양한 전송속도로 서비스하는 불완전 전력제어된 WCDMA 시스템의 역방향 링크에서 사용자 수 분포도에 따라 유도한 차단확률로부터 얼랑용량을 계산하고, COST231 WI(Walfisch-Ikegami) 모델로부터 전파손실을 계산해서 사용자 수와 셀 커버리지의 관계를 새롭게 제안하여 분석하였다. 데이터 전송속도 15 kbps에서 960 kbps 사이 음성과 데이터 사용자에 대한 얼랑용량은 상호 역 선형관계로 나타났고, 음성사용자를 8 kbps속도에서 50얼랑 기준으로 할 때 차단확률 2 %에서 $E_{b/}$ $N_{o}$ 가 4 ㏈에서 3 ㏈로 낮출 경우 15 kbps 저속에서는 데이터 용량이 8.5 얼랑 용량증가와 함께 도시 교외지역에서 셀 커버리지가 100 m 확장되었고, 960 kbps 고속에서는 0.11 얼랑 증가와 함께 셀 커버리지도 40 m 확장되었다. 여기서 차단확률을 조금 높였을 때 얼랑용랑은 증가하지만 셀 커버리지에는 별 영향이 없었고, 셀 내 사용자 수의 증가에 따라 셀 커버리지는 감소하였다.다.

• 대한세포병리학회지
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• 제11권2호
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• pp.109-114
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• 2000

Amyloid golfer is a rare disease entity that is defined as a symptomatic mass or clinically detectable thyroid enlargement because of amyloid deposition. We present a case of amyloid golfer diagnosed in the fine needle aspiration cytology(FNAC) in a 73-year-old Korean woman presented with nephrotic syndrome and thyroid enlargement. The thyroid function was in normal range. Thyroid scan showed a nodule, $4{\time}2cm$ in the right lobe with underlying diffuse golfer. Aspirates revealed benign looking follicular cells and scattered eosinophilic material. The sections of the cell block showed nodular deposit of eosinophilic hyalinized material in the interfollicular area. It showed apple-green birefringence under polarization with Congo red stain. The renal biopsy also exhibited deposition of eosinophilic materials in the glomeruli and interstitial vascular wall, which were confirmed as amyloidosis. This material was morphologically distinct from the colloid.

• 대한수의학회지
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• 제27권2호
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• pp.269-275
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• 1987

Radiation-induced life shortening, carcinogenesis and other pathological changes were investigated in NIH(GP) mice after $^{60}Co-{\gamma}$ ray irradiation(100~700rads). The results were summarized as follows: 1. There were little difference in body weights, hematological examination and other clinical findings between normal and irradiated groups. 2. Mean survival time of the mice after irradiation were decreased dose-dependently. 3. Main gross findings of the mice irradiated were appeared as enlargement of spleen, thymus and lymph nodes, tumorous nodules of lung and cyst of ovary. Especially, enlargement of thymus was promineort in high dose group. 4. Microscopically, there were various findings including myeloid leukemia, thymic lymphoma, lung adenoma, adenosquamous cell carcinoma of pancreas, pneumonia and other pathological changes. Especially thymic lymphoma was highly frequent in the 700 rads group.