• 제목/요약/키워드: Cell behavior

검색결과 1,374건 처리시간 0.029초

Multi-scale model for coupled piezoelectric-inelastic behavior

  • Moreno-Navarro, Pablo;Ibrahimbegovic, Adnan;Damjanovic, Dragan
    • Coupled systems mechanics
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    • 제10권6호
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    • pp.521-544
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    • 2021
  • In this work, we present the development of a 3D lattice-type model at microscale based upon the Voronoi-cell representation of material microstructure. This model can capture the coupling between mechanic and electric fields with non-linear constitutive behavior for both. More precisely, for electric part we consider the ferroelectric constitutive behavior with the possibility of domain switching polarization, which can be handled in the same fashion as deformation theory of plasticity. For mechanics part, we introduce the constitutive model of plasticity with the Armstrong-Frederick kinematic hardening. This model is used to simulate a complete coupling of the chosen electric and mechanics behavior with a multiscale approach implemented within the same computational architecture.

Acyl-Homoserine lactone Quorum Sensing in Bactreria

  • Greenberg, E.Peter
    • Journal of Microbiology
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    • 제38권3호
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    • pp.117-121
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    • 2000
  • Recent advances in studies of bacterial gene expression and light microscopy show that cell-to cell communication and communication and community behavior are the rule rather than the exception. One type of cell-cell communication, quorum sensing in Gram-negative bacteria involves acyl-homoserine lactone signals. This type of quorum sension represents a dedicated communication system that enables a given species to sense when it has reached a critical population density. and to respond by activating expression of specific genes. The LuxR and LuxI proteins of Vibrio fisheri are the founding members of the acyl-homoserine lactone quorum sensing signal receptor and signal generator families of proteins. Acyl-homeserine lactone signaling in Pseudomonas aeruginosa is one model for the relationship between quorum sensing community behavior, and virulence. In the P. aeruginosa model. quorum sensing is required for normal biofilm maturation and virulence. There are multiple quorum-sensing circuits that control the expression of dozens of specific genes in P. aeruginosa.

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연속 회분식 반응기를 이용한 폐수처리에서 고정화 슬러지의 거동 특성 (The behavior characteristics of immobilized sludge in waste water treatment using sequencing batch reactor(SBR).)

  • 최석순
    • 환경위생공학
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    • 제11권2호
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    • pp.1-7
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    • 1996
  • The behavior of total organic carbon (TOC) and phosphate were observed for 15 days with immobilized activated sludge using polyacrylamide (PAA) by sequencing batch reactor (SBR). In the preparation of immobilized sludge by PAA, it was found that suitable acrylamide concentration for actual wastewater treatment was to be 15% through the batch test. When SBR system was operated in the repeated aerobic and anaerobic conditions, TOC removal efficiency was 92%. The uptake rate of phosphate was increased from 1.78 mg-P/g cell/hr on the 5th day of acclimation to 2.5 mg-P/g cell/hr on the 15th day of acclimation. And the total phosphorus content in PAA bead was increased from 40 mg-P/g cell on the 1st day of operation to 55 mg-P/g cell on the 15th day of operation. From this study, lowering the volume of aeration tank was possible when PAA bead was used in wastewater treatment and long operation was also possible without the settler.

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Genetically Modified Human Embryonic Stem Cells Relieve Symptomatic Motor Behavior in a Rat Model of Parkinson′s Disease

  • 길광수;이영재;김은영;이창현;이훈택;정길생;박세필;임진호
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2003년도 학술발표대회 발표논문초록집
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    • pp.74-74
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    • 2003
  • Embryonic stem cells have several characteristics suitable for cell replacement therapy. To investigate a possibility of using human embryonic stem cell (hESC) as a carrier of therapeutic gene(s), hESC (MB03) was co-transfected with cDNAS coding for tyrosine hydroxylase (TH) and GTP cyclohydrolase Ⅰ (GTPCH Ⅰ) and bulk-selected using neomycin and hygromycin-B. Successful transfection was confirmed by western immunoblotting and RT-PCR. The genetically modified hESC (bk-THGC) relieved apomorphine-induced asymmetric motor behavior by approximately 54% when grafted into striatum of 6-OHDA-denervated rat brain. The number of rotation, however, increased up to 176+18% in 6 weeks when sham-grafted compared with number of rotation before graft. Immunohistochemical staining revealed that the grafted hESC survived and expressed TH for at least 6 weeks while the experiment was continued.

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Real-Time Optimal Control for Nonlinear Dynamical Systems Based on Fuzzy Cell Mapping

  • Park, H.T.;Kim, H.D.
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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    • pp.388-388
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    • 2000
  • The complexity of nonlinear systems makes it difficult to ascertain their behavior using classical methods of analysis. Many efforts have been focused on the advanced algorithms and techniques that hold the promise of improving real-time optimal control while at the same time providing higher accuracy. In this paper, a fuzzy cell mapping method of real-time optimal control far nonlinear dynamical systems is proposed. This approach combines fuzzy logic with cell mapping techniques in order to find the optimal input level and optimal time interval in the finite set which change the state of a system to achieve a desired obiective. In order to illustrate this method, we analyze the behavior of an inverted pendulum using fuzzy cell mapping.

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Discrete-Time CNN Using Chaos Circuits with Nonlinear function Controllability

  • Eguchi, Kei;Ueno, Fumio;Tabata, Torn;Zhu, Hongbing;Hamasaki, Yuuki
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2000년도 ITC-CSCC -2
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    • pp.1017-1020
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    • 2000
  • In this paper, a CNN using 1-dimensional chaos circuits with controllable nonlinear functions is proposed. The proposed CNN consists of $\p{times}q$ chaos circuits which are called cell circuits. The nonlinear functions of the cell circuits can be controlled by employing fuzzy scheme. Thanks to the controllability of the nonlinear functions, the proposed circuit can adjust transition behavior of the CNN electronically. Furthermore, the chaotic behavior of the cell circuit which is a portion of the proposed CNN is simple since the cell circuit is a 1-dimensional chaos circuit. To confirm the validity of the circuit design, SPICE simulations were performed concerning the proposed CNN.

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PEM 연료전지의 단순화된 공기극 채널 내 단일 물방울의 성장 및 이동 특성에 대한 실험적 연구 (Experimental investigation of growth and transport behavior of single water droplet in a simplified channel of PEM fuel cell)

  • 김보경;김한상;민경덕
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2006년도 춘계학술대회
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    • pp.81-84
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    • 2006
  • To investigate the characteristics of water droplet on the gas diffusion layer from both upper-view and side-view of flow channel, a rig test apparatus was designed and fabricated with L-shape acryl plate in a $1mm{\times}1mm$ micro-channel. This experimental device is used to simulate the single droplet growth and its transport process under fuel cell operating condition. As a first step, we investigated the growth and transport of single water droplet with working temperature and air flow velocity. The contact angle and its hysteresis of water droplet at departing moment are measured and analyzed. It is expected that this study can provide the basic understanding of liquid water droplet behavior in gas flow channel and GDL interface during the PEM fuel cell operation.

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PEM 연료전지 스택의 과도상태 출력특성에 관한 실험적 연구 (An Experimental Study on Transient Characteristics of PEM Fuel Cell Stack)

  • 김현일;황재순;정태용;신동훈;남진현;김영규
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2007년도 춘계학술대회B
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    • pp.2003-2008
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    • 2007
  • The transient power characteristics of a PEM fuel cell stack was experimentally studied using a commercial 1.2kW PEM fuel cell ($Nexa^{TM}$ Power Module, Ballard Power System Inc.). The conditions in PEM fuel cell stack such as temperature and water content change rather slowly because of their large heat capacity and long channel length, which results in long transient time to converge to a steady state. The steady characteristics of the PEM fuel cell module was determined first, followed by the measurement of its transient characteristics upon stepwise and continuous load current changes. During the stepwise current change from 5A to 25A, the output voltage initially decreased below the steady voltage and then increased gradually. Similar behavior was also observed for the stepwise current change from 25A to 5A. This transient behavior is explained with reference to the evolution of the temperature and water content of the PEM fuel cell stack.

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Cell Growing Behavior on the Electrospun PVA/GE nanofibermats.

  • Linh, Nguyen Thuy Ba;Nguyen, Thi-Hiep;Song, Ho-Yeon;Yang, Hun-Mo;Min, Young-Ki;Lee, Byong-Taek
    • 한국재료학회:학술대회논문집
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    • 한국재료학회 2009년도 추계학술발표대회
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    • pp.41.2-41.2
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    • 2009
  • Electrospinning of Polyvinylalcohol (PVA), Gelatin (GE), and PVA/GE blend solutions in acetic acid were investigated to fabricate biodegradable for tissue engineering. The morphology of the electrospun nanofibers was investigated with a field emission scanning electron microscope. The fibers have average diameters in the range 50-150 nm. The miscibility of PVA/GE blend fibers was examined by differential scanning calorimetry.The PVA and GE were immiscible in the as-spun nanofibrous structure. X-ray diffraction (XRD) determined the crystallinity of the membrane and tensile strength for evaluation physical properties. An in vitro study of PVA/GE blend nanofibers was conducted. To assay the cytocompatibility and cell behavior on the PVA/GE blend nanofibrous scaffolds, cell attachment and spreading of fibroblasts seeded on the scaffolds were studied. Our results indicate that thePVA/GE blend nanofibrous matrix, particularly the one that contained 20% PVA and 80% GE could be a good candidate for tissue engineering scaffolds, because it has an excellent cell attachment and spreading for fibroblast cell.

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Behavior of Rotating Stall Cell in a High Specific-Speed Diagonal Flow Fan

  • Shiomi, Norimasa;Cai, W.X.;Muraoka, A.;Kaneko, K.;Setoguchi, T.
    • Journal of Mechanical Science and Technology
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    • 제15권12호
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    • pp.1860-1868
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    • 2001
  • An experimental investigation was carried out to clarify unsteady flow fields with rotating stall cell, especially behavior of stall cell, in a high specific-speed diagonal flow fan. As its specific-speed is vary high for a diagonal flow fan, its pressure-flow rate curve tends to indicate unstable characteristics caused by rotating stall similar to axial flow fan. Although for an axial flow fan many researchers have investigated such the flow field, for a diagonal flow fan tittle study has been done. In this study, velocity fields at rotor Inlet in a high specific-speed diagonal flow fan were measured by use of a single slant hot-wire probe. These data were processed by using the "Double Phase-Locked Averaging"(DPLA) technique, i. e. phases of both the rotor blade and the stall cell were taken into account. The behaviors of stall cell at rotor inlet were visualized for the meridional, tangential and radial velocity.

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