• 한국수소및신에너지학회논문집
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• 제30권2호
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• pp.155-162
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• 2019

The energy management technology for an independent fuel cell-battery hybrid system is developed for a household usage. To develop an efficient energy management technology, a simulation model is first developed. After the model is verified with experimental results, three energy management schemes are developed. Three control techniques are a fuzzy logic control (FLC), a state machine control (SMC), and a hybrid method of FLC and SMC. As the fuel cell-battery hybrid system is used for a house, battery state of charge (SOC) regulation is the most important factor for an energy management because SOC should be kept constant every day for continuous usage. Three management schemes are compared to see SOC, power split, and fuel cell power variations effects. Experimental results are also presented and the most favorable strategy is the state machine combined fuzzy control method.

• Asian Pacific Journal of Cancer Prevention
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• 제16권2호
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• pp.689-692
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• 2015

Background: Incorporation of molecular analysis of the epidermal growth factor receptor (EGFR) gene into routine clinical practice has shown great promise to provide personalized therapy of the non-small cell lung cancer (NSCLC) in the developed world. However, the genetic testing of EGFR mutations has not yet become routine clinical practice in territories remote from the central regions of Russia. Therefore, we aimed to study the frequency of major types of activating mutations of the EGFR gene in NSCLC patients residing in West Siberia. Materials and Methods: We examined EGFR mutations in exons 19 and 21 in 147 NSCLC patients (excluding squamous cell lung carcinomas) by real time polymerase chain reaction. Results: EGFR mutations were detected in 28 of the 147 (19%) patients. There were 19 (13%) cases with mutations in exon 19 and 9 cases (6%) in exon 21. Mutations were more frequently observed in women (42%, p=0.000) than in men (1%). A significantly higher incidence of EGFR mutations was observed in bronchioloalveolar carcinomas (28%, p=0.019) and in adenocarcinomas (21%, p=0.024) than in large cell carcinomas, mixed adenocarcinomas, and NOS (4%). The EGFR mutation rate was much higher in never-smokers than in smokers: 38% vs. 3% (p=0.000). The frequency of EGFR mutations in the Kemerovo and Tomsk regions was 19%. Conclusions: The incorporation of molecular analysis of the EGFR gene into routine clinical practice will allow clinicians to provide personalised therapy, resulting in a significant increase in survival rates and improvement in life quality of advanced NSCLC patients.

• 전자공학회논문지
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• 제50권4호
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• pp.239-245
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• 2013

멀티 레벨 낸드 플레쉬 메모리에서 주위 셀의 문턱 전압상태에 따른 데이터 유지 특성을 연구하였다. 열을 가해 셀의 데이터 보전특성을 판정하는 열적 열하 특성에서 주목하는 셀의 문턱 전압이 변화하는데 문턱전압의 변화는 선택된 셀 주위에 있는 셀들이 가장 낮은 문턱 전압 상태로 있는 셀들의 수가 많을수록 커진다. 그 이유는 전하의 손실이 이루어지는 낸드 플레쉬 셀의 본질적인 특성 뿐 아니라, 주위 셀 사이의 측면 전계 때문이다. 전계에 대한 모사 결과로부터 전계의 증가 현상을 발견할 수 있고, 이로 인한 전하의 손실이 소자 스케일 다운에 따라 더 증가함을 알 수 있다.

• Journal of electromagnetic engineering and science
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• 제14권3호
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• pp.267-272
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• 2014

Hyperthermia is a form of cancer treatment in which affected human tissue is exposed to $>40^{\circ}C$ temperature. In this paper, our goal is to assess the efficacy of fullerene agents to reduce heating time for cancer treatment. Such agents can accelerate heating of cancer cells and improve hyperthermia treatment efficacy. Typically, in vitro testing involves cancer cell culturing, heating cell cultures in accordance to specifications, and recording cancer cell viability after hyperthermia. To heat cell cultures, we design and evaluate a 2.4-GHz microwave cavity with controllable temperature. The cavity is comprised of a polystyrene cell culture dish (diameter = 54 mm, height = 13.5 mm) and a printed monopole antenna placed within the cavity for microwave heating. The culture temperature can be controlled through the intensity and duration of the antenna's microwave radiation. Heating experiments were carried out to validate the cavity's performance for F-12K culture medium (Kaighn's F-12K medium, ATCC). Importantly, fullerene agents were shown to reduce heating time and improve hyperthermia treatment efficacy. The culture medium temperature increased, on average, from $24.0^{\circ}C$ to $50.9^{\circ}C$ (without fullerene) and from $24.0^{\circ}C$ to $56.8^{\circ}C$ (with 3 mg/mL fullerene) within 15 minutes.

• 대한화학회지
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• 제44권6호
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• pp.587-591
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• 2000

고분자액체의 상태방정식을 구하기 위하여 많은 이론들이 제안되어 왔다. 이론들의 대부분은 cell, hole, free volume 또는 lattice 등의 개념에 근거를 두고 있다. 가장 성공적인 이론중의 하나로 평가받고 있는 것이 free volume의 개념을 근거로 한 Flory의 상태방정식 이론이다. 본 연구에서는 Flory 이론에서 사용한 van der Waals 포텐셜을 수정하여 새로운 상태방정식을 만들었다. 계산결과 새로운 상태방정식은 Flory 이론보다 PVT 실험값과 더 잘 일치함을 알 수 있었다.

• The Korean Journal of Physiology and Pharmacology
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• 제27권5호
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• pp.457-470
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• 2023

The aim of this study was to investigate the role of kinesin superfamily member 15 (KIF15) in nasopharyngeal carcinogenesis (NPC) and explore its underlying mechanisms. We employed various assays, including the CCK-8 assay, flow cytometry, the Transwell and scratch assay, Western blotting, and nude mice transplantation tumor, to investigate the impact of KIF15 on NPC. Our findings demonstrate that KIF15 plays a critical role in the proliferation, apoptosis, migration, and invasion of NPC cells. Furthermore, we discovered that silencing KIF15 inhibits cell proliferation, migration, and invasion while promoting apoptosis, and that KIF15's effect on NPC cell growth is mediated through the PI3K/AKT and P53 signaling pathways. Additionally, we showed that KIF15 promotes nasopharyngeal cancer cell growth in vivo. Our study sheds light on the significance of KIF15 in NPC by revealing that KIF15 knockdown inhibits NPC cell growth through the regulation of AKT-related signaling pathways. These findings suggest that KIF15 represents a promising therapeutic target for the prevention and treatment of NPC.

• 전기학회논문지
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• 제58권4호
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• pp.700-707
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• 2009

The application of renewable energy in electric power systems is growing rapidly in order to make provision for the inequality of the climate, the dwindling supplies of coal, oil and natural gas and a further rise in oil prices. Solar cell generators(SCG) is one of the fastest growing renewable energy. This paper presents a methodology on probabilistic production cost simulation of a power system including SCGs. The generated power by SCGs is variable due to the random variation of solar radiation. In order to solve this problem, the SCGs is modeled as multi-state operational model in this paper. Probabilistic production cost of a power system can be calculated by proposed method considering SCGs with multi-state. The results show that the impacts of SCGs added to a power system can be analyzed in view point of production cost using the proposed method.

• Journal of Information Display
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• 제7권1호
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• pp.19-24
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• 2006

We propose optical configurations of a double-cellgap liquid crystal cell for transflective displays with wide viewing angle and high contrast ratio. The reflective part is designed in the wide-band quarter wave structure to achieve good dark state. For the transmissive part, the compensation method is applied to achieve the super-achromatic dark state, and three switching methods are used : which are vertical switching, horizontal switching to $30^{\circ}$and horizontal switching to $120^{\circ}$, to achieve the bright state.

• 한국광학회지
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• 제5권3호
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• pp.404-410
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• 1994

빛이 액정셀을 지날 때의 편광상태의 변화를 뽀앙카레공에서의 회전변환으로 나타내면 액정표시소자의 화면의 밝기와 명암대비는 이 회전변환의 특성(회전각과 회전축의 방향)의 함수로 나타낼 수 있다. 이로부터 액정 화면의 밝기와 명암대비를 동시에 극대화 하기위한 필요조건은 액정셀에 걸린 전압이 비선택전압에서 선택전압으로 바뀔 때의 회전변환의 회전각이 $180^{\circ}$임을 보였다.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 1993년도 Fifth International Fuzzy Systems Association World Congress 93
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• pp.972-974
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• 1993

This paper presents a new method to automatically design fuzzy logic controller(FLC). The main problems of designing FLC are how to optimally and automatically select the control rules and the parameters of membership function (MF). Cell state space algorithms (CSS), differential competitive learning (DCL) and multialyer neural network are combined in this paper to solve the problems. When the dynamical model of a control process is known. CSS can be used to generate a group of optimal input output pairs(X, Y) used by a controller. The(X, Y) then can be used to determine the FLC rules by DCL and to determine the optimal parameters of MF by DCL and to determine the optimal parameters of MF by multilayer neural network trained by BP algorithm.