• 한국환경보건학회지
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• 제44권5호
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• pp.468-479
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• 2018

Objectives: Recently, a report was published that the humidifier disinfectant CMIT/MIT did not cause developmental toxicity and was not detected in systemic circulation as a result of an inhalation toxicity test. Therefore, this study was carried out to investigate any associations between CMIT/MIT exposure and developmental toxicity using the in vivo apical toxicity test method. Methods: Groups of pregnant ICR mice were instilled in the trachea with chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) using a visual instillobot over a period of seven days from days 11 to 17 days post-coitum. For the in vivo apical toxicity test method, an $LD_{50}$-based dose-range finding model was applied to decide the dose range for inducing developmental toxicity. Results: Among the groups of 0, 0.1, 0.5, 1.0, and 1.5 mg ai/kg/day CMIT/MIT, the exposure groups of 0.5 mg and 1.0 ai/kg/day CMIT/MIT were estimated to reflect the thresholds for the stillbirth and death of pregnant mice, respectively. The groups of 0.5, 1.0, and 1.5 mg ai/kg/day CMIT/MIT induced stillbirth rates of 2.57, 10, and 53.8%, respectively. Another exposure group of 0.75 mg ai/kg/day CMIT/MIT did not induce any deaths of pregnant mice and resulted in a stillbirth rate of 8% in only one of six pregnant mice. Conclusions: CMIT/MIT can induce stillbirth in pregnant mice. It was also concluded that CMIT/MIT moves through the pulmonary circulation system and then continues on through systemic circulation and the placenta. There is a possibility of stillbirth and other health causalities in humans beyond the lungs caused by CMIT/MIT exposure.

• Nutrition Research and Practice
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• 제7권3호
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• pp.192-198
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• 2013

Dietary sodium intake is considered one of the major causal factors for hypertension. Thus, to control the increase of blood pressure and reduce the risk of hypertension-related clinical complications, a reduction in sodium intake is recommended. The present study aimed at determining the association of dietary sodium intake with meal and snack frequency, snacking time, and taste preference in Korean young adults aged 20-26 years, using a 125-item dish-frequency questionnaire. The mean dietary sodium intakes of men and women were 270.6 mmol/day and 213.1 mmol/day, which were approximately 310% and 245% of the daily sodium intake goal for Korean men and women, respectively. Dietary sodium intake was positively correlated with systolic blood pressure in the total group, and BMI in the total and men-only groups. In the total and men-only groups, those who consumed meals more times per day consumed more dietary sodium, but the number of times they consumed snacks was negatively correlated with dietary sodium intake in the total, men-only, and women-only groups. In addition, those who consumed snacks in the evening consumed more sodium than those who did so in the morning in the men-only group. The sodium intake was also positively associated with preference for salty and sweet taste in the total and women-only groups. Such a high intake of sodium in these young subjects shows that a reduction in sodium intake is important for the prevention of hypertension and related diseases in the future.

• 노동경제논집
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• 제29권1호
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• pp.1-39
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• 2006

본 논문은 우리나라 노동시장에서 1990년대에 소득 변동성이 증가한 양상을 실증적으로 추정하고, 이러한 소득 변동성의 증가가 자본시장의 개방에 의해 설명될 수 있는지 분석하였다. 소득 변동성 추정에 있어서는 패널 자료가 아닌 반복 횡단면 자료에 간단한 계량모형을 적용하여 임금소득의 일시적 변화와 항구적 변화에 대한 분산을 추정하였다. 1990년대 소득 변동성의 증가 추세는 1992년 주식시장 개방을 필두로 한 우리나라 자본시장 개방과 시기적으로 일치하는 것으로 보이나, 산업 차원에서의 횡단면 분석에 의하면 양자간의 인과관계는 강하지 않은 것으로 추정된다. 다만 외국인 직접투자의 경우 고학력 근로자의 일시적 소득 변동성은 줄이는 효과를, 저학력 근로자의 일시적 소득 변동성은 증가시키는 효과를 갖는 것으로 추정되었다. 이와 같이 근로자 유형별로 비중립적인 효과를 갖는 것은, 자본과 기능의 보완성에 따른 효과로 판단된다. 한편 일시적 소득 변동성이 자본시장에서 충분히 분산될 수 없다면, 이러한 외국인 직접투자의 비중립적 효과는 "임금소득의 변동성"이라는 측면에서 근로자 유형별 복지의 격차를 유발시킬 가능성이 있다고 판단된다.

• 노동경제논집
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• 제34권3호
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• pp.81-117
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• 2011

본 연구는 2007년 7월부터 도입되었던 비정규직법 중 비정규직 근로자에 대한 차별적인 처우를 금지하는 규정이 기업들의 차별시정 노력에 어떤 영향을 미쳤는지를 분석하였다. 차별시정법이 기업 규모에 따라 단계적으로 적용되었다는 점에 착안하여 이중차분법을 적용하여 추정한 결과, 임금은 물론 퇴직금제도나 연차휴가 제도 또는 4대 보험 등 다양한 복리후생 분야에서 유의한 차별시정법의 효과를 발견할 수 없었다. 차별시정법이 소기의 목적을 달성하기 위해서는 기업들의 차별시정 노력이 미진한 원인에 대한 분석과 보완책이 마련되어야 할 것이다.

• 자원ㆍ환경경제연구
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• 제21권4호
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• pp.893-920
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• 2012

본 연구는 한국 노동패널(KLIPS) 제1차~제12차년도 자료를 이용하여 개인의 전반적 생활만족도(life satisfaction)와 대기오염 사이에 어떤 연관관계가 있는가를 순서형 프로빗(Ordered Probit) 모형으로 추정하였다. 기존 연구에서 고려하고 있는 다양한 개인의 경제적 특성과 사회 인구학적 특성을 동시에 고려하였다. 실증분석 결과 대기오염도는 개인의 생활만족도에 부정적인 영향을 미치는 것으로 나타났다. 그 외에 다른 변수들은 기존의 많은 연구결과와 유사한 결론을 보여 주었다. 소득이 증가할수록 생활만족도가 높아지나 어느 수준이 지나면 증가폭이 작아지는 비선형 효과가 나타나 이스털린 역설(Easterlin's paradox)이 의미하는 바가 한국에서도 어느 정도 나타나고 있음을 보여주었다. 본인이 속한 지역의 1인당 소득으로 측정한 타인의 소득 증가는 생활만족도에 부정적 영향을 미치지만, 결혼, 자가주택 보유, 건강, 높은 교육수준은 생활만족도에 긍정적인 영향을 미치고, 가구원수가 많은 가구 구성원, 도시거주자, 실업자, 자영업자인 경우는 생활만족도에 부정적인 영향을 미치는 것으로 나타났다.

• 산경연구논집
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• 제10권12호
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• pp.43-55
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• 2019

Purpose : With the proliferation of O2O platform services that combine offline and online services, many startups are fiercely competing to lead services in the O2O service market. While the prospects for growth in the O2O service market are optimistic because of the close convenience to life, startups can achieve corporate performance only through close cooperation and partnership with suppliers. The purpose of this study is to verify the effect of O2O-based startups' and suppliers' cooperation in supply chain management on SCM performance through supply chain partnerships and startup satisfaction with suppliers. Research design, data, methodology : Data were collected from O2O service-based startups and hypotheses were verified through frequency analysis, exploratory factor analysis, reliability analysis, confirmatory factor analysis, feasibility analysis, and structural equation path analysis. In addition, the mediating effects of supply chain partnerships and startup satisfaction on suppliers were verified. Results : As a result of this study, IT utilization of the O2O startup cooperation method affects the financial perspective of supply chain partnership and SCM performance. The contract implementation of the cooperation method had an impact on the financial and innovation growth perspectives of the SCM performance, and the communication of the cooperation method had an effect on the supply chain partnership, startup satisfaction in the supply chain, and the innovation growth perspective of the SCM performance. Supply chain partnerships had an impact on the financial, innovation growth, and customer perspectives of SCM performance and startup satisfaction within the supply chain had a significant effect on innovation growth and customer perspectives. Conclusions : The implications of this study identified the factors that can improve SCM performance through the cooperation method of O2O startup, supply chain partnership and startup satisfaction with suppliers, and it is significant that the causal relationship was identified by the structural model through the supply chain cooperation factors derived by characteristics. Based on the empirical results, as the services of O2O startups grow, it is expected that empirical research and practical activation of academia should be considered as important in the cooperation of the supply chain.

• Asian Pacific Journal of Cancer Prevention
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• 제15권23호
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• pp.10489-10493
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• 2015

Background: Gastric cancer is the second most common gastrointestinal cancer and is largely attributed to Helicobacter pylori (H. pylori) infection. In addition, studies have also shown association with Epstein-Barr virus (EBV) in 10% of gastric cancers. This study assessed the characteristics of EBV associated gastric cancers (EBVaGC) in Brunei Darussalam. Materials and Methods: This study included gastric cancers diagnosed between 2008 and 2012, registered with the Department of Pathology RIPAS Hospital, Brunei Darussalam. Clinical case notes were systematically reviewed. Histology specimens were all stained for EBV and also assessed for intestinal metaplasia and H. pylori. Results: There were a total of 81 patients (54 male and 27 females) with a mean age of $65.8{\pm}14.8years$ included in the study. Intestinal metaplasia and active H. pylori infection were detected in 40.7% and 30.9% respectively. A majority of the tumors were proximally located (55.6%), most poorly differentiated (well differentiated 16%, moderately differentiated 30.9% and poorly differentiated 53.1%) and the stages at diagnosis were; stage I (44.4%), stage II (23.5%), stage III (8.6%) and stage IV (23.5%). EBV positivity (EBVaGC) was seen in 30.9%. Between EBVaGC and EBV negative gastric cancers, there were no significant differences (age, gender, ethnic group, presence of Intestinal metaplasia, tumor locations, stages of disease and degree of tumor differentiation). Conclusions: This study showed that a third of gastric cancers in Brunei Darussalam were positive for EBV, higher than what have been reported in the literature. However, there were no significant differences between EBVaGC and EBV negative gastric cancers. This suggests that the role of EBV in gastric cancer may be mostly incidental rather than any causal relation. However, further studies are required.

• The Korean Journal of Pain
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• 제23권1호
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• pp.28-34
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• 2010

Background: An independent medical examination (IME) is a critical process for awarding reparation for injury. However, conducting an IME in pain medicine is very difficult, not only because pain is a subjective symptom, but also because there are no proper objective methods to demonstrate it. This study was conducted to compare IME reports and the court decisions on the disability status of the patients. Methods: We analyzed 79 IME reports and 25 corresponding court decisions on the disability status of patients. The diagnoses, causal relationships between the patients' status and the trauma, McBride's degree of disability, the American Medical Association's impairment ratings, the estimated annual cost for future treatment, and the necessity of care-giving were compared and analyzed. Results: The diagnoses in the 79 cases were complex regional pain syndrome (CRPS) type I (58 cases), CRPS type II (7 cases), peripheral neuropathy (5 cases), myofascial pain syndrome (4 cases), herniated intervertebral disc (2 cases), and fibromyalgia (1 case). The types of accidents were road traffic accidents (50 cases), military injuries (14 cases), industrial accidents (11 cases), and others (4 cases). The IME reports and the court decisions stated considerably different McBride's degrees of disability (P = 0.014). However, there was no significant difference in the estimated cost for future treatment between the IME reports and the court decisions (P = 0.912). Conclusions: IME reports should be accurate, fair, and based on objective findings. Feedback on IMEs from the court decisions is helpful for reference use.

• 자원ㆍ환경경제연구
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• 제21권3호
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• pp.573-593
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• 2012

본 연구는 1980~2009년 동안 한국의 경제성장과 총 전력소비 및 산업별 전력소비 사이의 인과관계를 분석하였다. 이를 위해 단위근 검정을 실시하였으며 그 결과, 실질 GDP, 제1차 산업, 제조업 그리고 총 전력소비는 1차 차분형태의 안정적인 변수로 나타났다. 그러나 서비스업 전력소비는 2차 차분을 실시했을 때에 안정적인 변수로 나타났다. 공적분 검정을 실시한 결과, 실질 GDP와 총 전력소비 및 산업별 전력소비 사이에는 장기균형 관계가 존재하지 않는 것으로 분석되었다. 따라서 표준 Granger 인과관계 검정에 의하면, 경제성장이 총 전력소비, 제1차 산업 및 제조업의 전력소비에 영향을 주는 일방향 인과관계가 존재하는 것으로 나타났다. 그러나 서비스업 전력소비는 경제성장과 아무런 인과관계를 발견할 수 없었다. 이러한 인과성은 전력부문의 가격 및 비가격정책 등이 경제성장에 부정적인 영향을 최소화하면서 실행될 수 있음을 의미한다.

• 한국생활과학회지
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• 제18권5호
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• pp.995-1008
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• 2009

This study investigated the causal relationships among the elderly, looking at social participation, depression, self-reported health, and life satisfaction. It was especially focused on the mediating effects of depression and self-reported health on the relationship between social participation and life satisfaction. From the 2006 Korean Longitudinal Study of Aging, data for 4,155 elderly over age 65 was analyzed with structural equations modeling with Amos 7.0 and sobel test. Major findings were as follows. First, social participation of the elderly has a negative influence on depression and a positive influence on self-reported health and life satisfaction. Second, self-reported health has a partial mediating effect on the relationship between social participation and life satisfaction. Third, the direct effect of depression on life satisfaction was not statistically significant, while the direct effect of social participation was significant. Therefore, depression was not proved as a significant mediator. This study tested the effects of social participation on depression, self-reported health, and life satisfaction empirically and confirmed the partial mediating model, in which social participation improves the elderly's self-reported health, which in turn improves the elderly's life satisfaction. These results suggest the importance of an integrated approach for the healthy and successful aging and the diverse types of social participation in an elderly person's quality of life.