• Title/Summary/Keyword: Castleman Disease

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Chordoid Meningioma

  • Choi, Kyung-Chul;Joo, Won-Il;Jang, Kyung-Sool;Kim, Moon-Chan
    • Journal of Korean Neurosurgical Society
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    • v.38 no.5
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    • pp.390-392
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    • 2005
  • A case of chordoid meningioma occurring in a 61-year-old woman who did not have a Castleman's disease is presented. The patient had suffered from headache and motor dysphasia. Laboratory findings are normal. The tumor, located in the left frontal region and associated with peritumoral edema, was totally resected. Surgical specimen revealed a solid mass with irregular surface that measured $3.5{\times}4.5{\times}4cm$. Immunohistochemical staining revealed that the tumor cells expressed epithelial membrane antigen[EMA] focally, but not S-100 protein and glial fibrillary acid protein [GFAP], and the Ki-67 proliferative index of the tumor was 9%. The neoplasm was diagnosed chordoid meningioma of the World Health Organization[WHO] grade II. After total resection, her preoperative headache and dysphasia were disappeared.

A Case of Cervical Malignant Lymphoma Coexisted with Multicentric Castleman's Disease (다발성 캐슬만병과 공존한 경부 악성 림프종 1례)

  • Jang, Gyu Ho;Jung, Young Do;Seo, Youn Tae;Kim, Jeong Kyu
    • Korean Journal of Head & Neck Oncology
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    • v.32 no.2
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    • pp.35-39
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    • 2016
  • Castleman's disease (CD) is an uncommon lymphoproliferative disorder. The disease entity is classified into 2 clinical subtypes, unicentric and multicentric type. Prevalence of lymphoid malignancy in multicentric CD (MCD) is very low. In this case, we report a case of 77 years old woman who developed high fever and swelling in both side of her neck. Neck lymph node biopsy revealed plasma cell hyperplasia. Patient's symptom was subsided after treatment with Dexamethasone. Three months later, multiple lymph node enlargement was developed in abdomen and neck area again. Repeated neck lymph node biopsy confirmed diffuse large B cell lymphoma. The patient started chemotherapy.

A Mediastinal Mass (종격동 종괴)

  • Park, Joon-Yong;Kim, Byeong-Cheol;Kim, Jin-Ho;Yoon, Ho-Joo;Shin, Dong-Ho;Park, Sung-Soo;Lee, Jung-Hee
    • Tuberculosis and Respiratory Diseases
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    • v.42 no.1
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    • pp.115-118
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    • 1995
  • A 32-year-old female was admitted for evaluation of known mass on right suprahilar area. Chest PA showed $4{\times}3cm$ round and homogenous mass on suprahilar area. No abnormal findings were found in PFT, cytology, bacterial study, and fine needle aspiration biopsy(FNAB). On chest computed tomography, solitary mass was on right suprahilar area and no evidence of intrapulmonary metastasis or lymphnode metastasis was seen. Right upper lobectomy of lung was performed and Castleman's disease of hyaline vascular type was diagnosed based on the histologic findings of multiple and large lymphoid follicles with prominent vascular proliferation and hyalization in the central portion.

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Rare Location of Castleman's Disease in the Temporal Region: A Case Report Involving a Young Korean Woman and Review of the Literature

  • Ryu, Wan Cheol;Park, Moon Hyang;Kim, Hoon;Koh, In Chang;Kim, Kyu Nam
    • Archives of Craniofacial Surgery
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    • v.18 no.2
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    • pp.122-127
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    • 2017
  • Castleman's disease (CD) is an uncommon benign lymphoproliferative disorder of unknown etiology. Histopathologically, it is divided into three types: hyaline-vascular, plasma cellular, and multicentric CD. The mass usually presents asymptomatically; however, it can cause non-specific symptoms such as fever and fatigue. Although CD can be found wherever lymph nodes are present, 75% of cases are reported in the mediastinum, and occurrence in the head and neck is rare. Herein, we report a rare case of CD presenting as a superficial mass in the temporal region. To the best of our knowledge, this is the first report of temporal CD in Korea involving a young patient.

A Case of Giant Lymph Node Hyperplasia in the Spermatic Cord (정색을 침범한 거대 림프양 증식증 1례)

  • Shin, Hyun-Chul;Kim, Young-Soo;Park, Tong-Choon;Shim, Young-Ran
    • Journal of Yeungnam Medical Science
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    • v.9 no.1
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    • pp.175-180
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    • 1992
  • Giant lymph node hyperplasia(Castleman's disease) is a rare disease, which represents a peculiar form of lymph node hyperplasia. Generally, it has been considered as benign and localized disease but recently, revealed malignant transformation in some cases of multicenteric form. It usually occurs on the mediastinum and occasionaly neck, lung, axilla, mesentery, broad ligament, retroperitoneum or soft tissue of extremities. Histopathologically, it is divided into hyaline vascular or plasma cell type and the former is characterized with prominent vascular proliferation and hyalinization in the central portion and tight concenteric layering of lymphocytes at the periphery of the fillicles(mantle zone) and the latter is characterized by a diffuse plasma cell proliferation in the interfollicular area. From the point of view of clinical presentation, it has been divided into solitary form, which presents as a localized mass located most commonly in the mediastinum, and multicenteric form, which occurs multiple location and has systemic manifestation arid transformation into malignancy. Herein we report a case of Giant lymph node hyperplasia occuring in the left spermatic cord in a 58-year old male with brief review of literatures.

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Thoracic Splenosis after Splenic and Diaphragmatic Injury

  • Ha, You Jin;Hong, Tae Hee;Choi, Yong Soo
    • Journal of Chest Surgery
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    • v.52 no.1
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    • pp.47-50
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    • 2019
  • Thoracic splenosis is a rare disease that develops as a result of autotransplantation of splenic tissue into the thoracic cavity following splenic and diaphragmatic injury. We report the case of a 53-year-old man with a chief complaint of heartburn and cough. He had a history of traumatic diaphragmatic rupture treated with surgical repair and splenectomy 15 years ago. Imaging studies revealed a paraesophageal mass, and surgical resection was performed considering the possibility of Castleman disease or an esophageal submucosal tumor. Pathologic results showed findings of normal splenic tissue. The patient was discharged on postoperative day 5 without any complications.

Extracardiac Uptake of Thallium-201 during Myocardial Perfusion Imaging with Pharmaeologic Vasodilation (심근관류 스캔중에 나타난 Thallium-201의 심장외 국소적 섭취)

  • Choi, Chung-Il;Kwak, Dong-Suk;Chung, Byung-Cheon;Park, Moo-Keun;Lee, Jae-Tae;Lee, Kyu-Bo
    • The Korean Journal of Nuclear Medicine
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    • v.26 no.1
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    • pp.65-71
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    • 1992
  • Myocardial perfusion imaging with $^{201}Tl-chloride$ following exercise or vasodilator-induced hyperemia has been effective in detecting the presence of coronary artery disease. An increased lung uptake of thallium has been reported as a sensitive marker of severe and extensive coronary artery disease and associated with poor prognosis. Thallium has also been noted to concentrate in a variety of malignant lesions. We report 5 cases of extracardiac uptake of thallium during myocardial perfusion scan with pharmacologic vasodilation. Accumulation of thallium was found in the lesions of a breast cancer, a lung cancer, a Castleman's disease and 2 cases of thymoma. We believe that the presence of focal extracardiac uptake of thallium during myocardial perfusion scan should suggest the need for further clinical evaluation to detect the tumor and must differentiate the increased lung uptake of thallium due to left ventricular dysfunction in coronary artery disease.

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