• 제목/요약/키워드: Cassia occidentalis

검색결과 3건 처리시간 0.014초

Protective effects of Hydro-alcoholic extract of the roots of Kasondi (Cassia occidentalis L.) against gentamicin-induced nephrotoxicity in albino Wistar rats

  • Jwariya Shamim;Athar Parvez Ansari;Pankaj Goswami;Seema Akbar;Huzaifa Ansari;Abdul Wadud;Pervaiz Ahmad Dar
    • 셀메드
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    • 제13권6호
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    • pp.5.1-5.8
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    • 2023
  • Objectives: Cassia occidentalis L. is a weed belonging to the Caesalpiniaceae family. The root of this medicinal plant is used for the treatment of various ailments, including kidney diseases. The present study was aimed at evaluating the nephroprotective effects of HAE of the roots of Cassia occidentalis L. against gentamicininduced renal toxicity in albino Wistar rats. Methods: The renal toxicity was induced by subcutaneous administration of gentamicin at 100 mg/kg in the rats belonging to the disease control and treatment groups from the 4th to the 8th day. The rats in the treatment group received HAE of the roots of Cassia occidentalis L. at 67 mg/kg b. w. orally for 8 days, while no treatment was given to the rats in the disease control and plain control groups. At the end of the experiment, renal biomarkers viz; s. creatinine, b. urea, and s. uric acid, were investigated. The histopathological examination of the kidney specimens was also carried out. Results: The results of the present study revealed that renal function biomarkers such as s. creatinine, b. urea, and s. uric acid were significantly reduced in the rats of the treatment group as compared to those of the disease control group. Moreover, the histoarchitecture reports of the treatment group's kidney specimens showed significant improvements. Conclusion: The results suggested that the HAE of Cassia occidentalis L. roots promisingly prevented kidney injury in gentamicin-induced nephrotoxic rats. This effect might be due to improved clearance of gentamicin from the renal tubule and decreased generation of reactive oxygen species (ROS).

Acacia melanoxylon 잎 메탄올 추출액의 생물활성 (The Bioefficacy of Methanol Crude Leaf Extract of Acacia melanoxylon)

  • ;;;;길봉섭
    • The Korean Journal of Ecology
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    • 제21권6호
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    • pp.805-808
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    • 1998
  • The methanolic crude leaf extract of Acacia melanoxylon shows inhibitory effects on seed germination, shoot growth, root growth and biomass of black gram (Phaseolus mungo L. Co 1) and weeds (Cassia occidentalis L. and Cyperus rotundus L.). The post emergence treatment was given on the 8th day after sowing and 4-6 days after seedling emergence. After postemergence treatment with 20% extract concentration, wilting symptoms appeared in P. mungo and C. occidentalis while necrosis occurred in C. rotundus. The seedling growth was inhibitory at all concentrations (5%, 10%, 20%) as compared to control plants. This inhibitory effect may be due to the presence of allelochemicals like phenolics in the A. melanoxylon leaves. Different types of phenolic acids were identified.

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우리나라 란 바이러스에 관한 연구 (Studies on Virus Diseases of Orchids in Korea)

  • 이현숙;나용준
    • 한국응용곤충학회지
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    • 제15권3호
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    • pp.137-145
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    • 1976
  • 우리나라에서의 바이러스 무감염란 생산에 필요한 기초자료를 얻기 위하여 Cymbidiun mosaic virus와 Tobacco mosaic virus를 중심으로 그 감염상 및 감염된 바이러스의 혈청학적 반응, 검정식물상의 반응, 물이적 성질, 형태등을 조사하여 다음과 같은 결과를 얻었다. 1. 란에 발생하는 바이러스병의 병징은 크게 1) 모자이크, 2) 괴저줄무늬 모자이크, 3) 괴원륜문, 4) 퇴록륜문 및 5) 괴달반점의 5군으로 분류되었다. 2. 수원근교의 난 재배농장에서 수집한 각종란의 바이러스 이병률을 조사한 결과 CyMV는 $45\%$의 감염율을 나타내었고, TMV는 한개체에서도 검출되지 않았다. 3. CyMV의 검정식물인 Chenopodium amaranticolor, Cassia occidentalis 및 Datura stramonium에 CyMV 병즙액을 접종한지 7-12일 후에 퇴록국부반점이 나타났다. 4. CyMV의 물리적 성질을 Chenopodium amaranticolor를 검정식물로 하여 조사한 결과, 내열성은$75-80^{\circ}C$ 내보존성은 8일, 내포석성은 $10^{-5}-10^{-6}$으로 나타났다. 5. CyMV의 혈정학적 한천내 확산반응에 사용된 0.1M 및 0.01M의 Phosphate, Imidazol 및 Tris 완충간에는 침강대 형성에 차이를 볼 수 없었다. 그러나 이들 완충액의 수소이온농도간에는 침강대 형성에 심한 차이를 나타내어, pH 7.0에서는 침강대가 뚜렷하였고 pH9.0에서는 미약하였다. 6. CyMV를 전자현미경으로 관찰한 결과 크기 460-580mu의 간상입자의 빈도가 제일 높았다.

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