• Asian Pacific Journal of Cancer Prevention
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• 제15권19호
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• pp.8301-8310
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• 2014

Background: Published data regarding associations between the -765G>C polymorphism in cyclooxygenase-2 (COX-2) gene and digestive system cancer risk have been inconclusive. The aim of this study was to comprehensively evaluate the genetic risk of the -765G>C polymorphism in the COX-2 gene for digestive system cancer. Materials and Methods: A search was performed in Pubmed, Medline (Ovid), Embase, CNKI, Weipu, Wanfang and CBM databases, covering all studies until Feb 10, 2014. Statistical analysis was performed using Revman5.2. Results: A total of 10,814 cases and 16,174 controls in 38 case-control studies were included in this meta-analysis. The results indicated that C allele carriers (GC+CC) had a 20% increased risk of digestive system cancer when compared with the homozygote GG (odds ratio (OR)=1.20, 95% confidence interval (CI), 1.00-1.44 for GC+CC vs GG). In the subgroup analysis by ethnicity, significant elevated risks were associated with C allele carriers (GC+CC) in Asians (OR = 1.46, 95% CI=1.07-2.01, and p=0.02) and Africans (OR=2.12, 95% CI=1.57-2.87, and p< 0.00001), but not among Caucasians, Americans and mixed groups. For subgroup analysis by cancer type (GC+CC vs GG), significant associations were found between the -765G>C polymorphism and higher risk for gastric cancer (OR=1.64, 95% CI=1.03-2.61, and p=0.04), but not for colorectal cancer, oral cancer, esophageal cancer, and others. Regarding study design (GC+CC vs GG), no significant associations were found in then population-based case-control (PCC), hospital-based case-control (HCC) and family-based case-control (FCC) studies. Conclusions: This meta-analysis suggested that the -765G>C polymorphism of the COX-2 gene is a potential risk factor for digestive system cancer in Asians and Africans and gastric cancer overall.

• 지역사회간호학회지
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• 제13권1호
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• pp.30-38
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• 2002

The purpose of this study was to compare the Depression levels of the poor and elderly as well as the elderly who were residents in a community. The author studied the Depression levels of 117 poor and elderly individuals and 183 elderly individuals all 65 years or older living in Suwon City. This study has been done using a direct-interview structured Questionnaire and Korean Form of Geriatric Depression Scale (KGDS) from May to July in 1999. The results can be summarized as following: 1. With Case and Control group there was no significant difference with respect to gender, age, education level, or religion. But was significantly different regarding marriage state, if subjects were living together, type of residency, province, and place of toilet(P<0.05). 2. Smoking and Hwa-pyung was a large number of case group more than control group. and alcohol was more control group than case group(P<0.05). 3. There was a similiar taking medicine and kind of body symtom of case and control group. 4. The mean score of perceived KGDS of the poor elderlys was 17.87+/-5.97 out of 30. and that of the elderlys was 13.35+/-6.00 out of 30(P<0.001). 5. In a simple correlation analysis of elderlys. education, marital status. residency, son and daughter, position of toilet, elderly center, alcohol, Wha-byung, disease. 6. In a multiple regression analysis, Hwa-byung, elderly center, education, smoking, disease, son and daughter.

• Journal of Preventive Medicine and Public Health
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• 제39권2호
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• pp.177-183
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• 2006

Objectives : In this study we examined the association between the genetic markers ACE (A-240T, C-93T, I/D, A2350G), AGT (M235T), AT1R (A1166C), CYP11B2 (T344C, V386A), REN (G2646A), ADRB2 (G46A, C79G, T47C, T1641), GNB3 (C825T) and ADD1 (G460W) and the presence of essential hypertension in adolescents. Methods : The Kangwha Study is an 18-year prospective study that is aimed at elucidating the determinants of the blood pressure level from childhood to early adulthood. For this study, we constructed a case-control dataset of size of 277 and 40 family trios data from the Kangwha Study. For this purpose, we perform a single locus-based case-control association study and a single locus-based TDT (transmission/disequilibrium test) study. Results : In the case-control study, the single locus-based association study indicated that the ADD1 (G460W) (p=0.0403), AGT (M235T) (p=0.0002), and REN (G2646A) (p=0.0101) markers were significantly associated with the risk of hypertension. These results were not confirmed on the TDT study. This study showed that genetic polymorphisms of the ADD1, AGT and REN genes might be related to the hypertension in Korean adolescents. Conclusions : This study provided useful information on genetics markers related to blood pressure. Further study will be needed to confirm the effect of the alpha adducin gene, the angiotensinogen gene and the renin gene on essential hypertension.

• Smart Structures and Systems
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• 제21권6호
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• pp.777-791
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• 2018

This paper discusses the shape control of deformable mirrors for Adaptive Optics in the dynamic range. The phenomenon of control-structure interaction appears when the mirror becomes large, lowering the natural frequencies $f_i$, and the control bandwidth $f_c$ increases to improve the performance, so that the condition $f_c{\ll}f_i$ is no longer satisfied. In this case, the control system tends to amplify the response of the flexible modes and the system may become unstable. The main parameters controlling the phenomenon are the frequency ratio $f_c/f_i$ and the structural damping ${\zeta}$. Robustness tests are developed which allow to evaluate a lower bound of the stability margin. Various passive and active strategies for damping augmentation are proposed and tested in simulation.

• 한국도로학회논문집
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• 제16권5호
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• pp.109-119
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• 2014

PURPOSES : The control delay in seconds per vehicle is the most important traffic operational index to evaluate the level of service of signalized intersections. Thus, it is very critical to calculate accurate control delay because it is used as a basic quantitative evidence for decision makings regarding to investments on traffic facilities. The control delay consists of time-in-queue delay, acceleration delay, and deceleration delay so that it is technically difficult to directly measure it from fields. Thus, diverse analysis tools, including CORSIM, SYNCHRO, T7F, VISTRO, etc. have been utilized so far. However, each analysis tool may use a unique methodology in calculating control delays. Therefore, the estimated values of control delays may be different by the selection of an analysis tool, which has provided difficulties to traffic engineers in making solid judgments. METHODS : This study was initiated to verify the feasibility of diverse analysis tools, including HCM methodology, CORSIM, SYNCHRO, T7F, VISTRO, in calculating control delays by comparing estimated control delays with that measured from a field. RESULTS : As a result, the selected tools produced quite different values of control delay. In addition, the control delay value estimated using a calibrated CORSIM model was closest to that measured from the field. CONCLUSIONS : First, through the in-depth experiment, it was explicitly verified that the estimated values of control delay may depend on the selection of an analysis tool. Second, among the diverse tools, the value of control delay estimated using the calibrated microscopic traffic simulation model was most close to that measured from the field. Conclusively, analysts should take into account the variability of control delay values according to the selection of a tool in the case of signalized intersection analysis.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1992년도 한국자동제어학술회의논문집(국제학술편); KOEX, Seoul; 19-21 Oct. 1992
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• pp.7-10
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• 1992

This lecture is about an investigation into a desired property of fuzzy systems when degrees of uncertainty involved are uncertain. We characterize the robustness of fuzzy logic operators by their moduli of continuity. Theoretical results for design methodology are presented and a case study is discussed.

• 한국습지학회지
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• 제24권1호
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• pp.38-43
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• 2022

스마트(Smart) 하수처리장은 하수처리 전 과정에 대한 ICT 기반의 실시간 모니터링, 원격 제어 관리 및 지능화 체계를 구축하여 안전하고 깨끗한 물환경을 조성하는 것을 의미한다. 이러한 스마트 하수처리장의 핵심이 되는 기술이 계측기를 활용한 운전제어 기술이라 할 수 있다. 본 연구진은 국내에서 진행중인 하수처리장 지능화 연구사업들을 참고하여 지능화사업 구축 시 필요한 운전제어 기술들을 분석하고 제시하였다. 분석 결과 규모별 제어, 반류수 제어, 연계처리수 제어, 약품량 제어, 동절기 운영제어, 총 유기탄소 제어까지 총 6개의 제거 기술에 대해 제시하였다. 규모별로는 소규모와 중규모 대규모로 구분할 수 있는 기준을 제시하였고, 반류수 제어의 경우 반류수를 관리할 수 있는 수질 및 유량 센서의 위치를 제시하였다. 연계처리수 제어의 경우 연계처리수가 하수처리장에 미치는 영향과 제어 지점을 제시하였으며, 약품주입량 제어의 경우 지능형 하수처리장 도입에 따라 약품 주입량을 최적화할 수 있는 시스템을 제시하였다. 동절기 운영의 경우 수온 저하에 따른 질산화 저하를 고려하였을 때 제어해야 하는 센서와 펌프를 제시하였다. 총 유기탄소 제어의 경우 향후 오염총량제를 고려한 연동 시스템을 제시하였다. 이러한 운전제어 시나리오들은 향후 지능형 하수처리 알고리즘과 시나리오에 사용될 기초자료로 활용될 수 있을 것으로 판단된다.

• 한국자동차공학회논문집
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• 제22권4호
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• pp.82-88
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• 2014

Recliner of automotive seat has the function to control the angle and has a close relation to the safety of seat. Therefore each of parts constituting recliner is important and recliner case to protect these parts from various dynamic loads is also important. As two kinds of recliner cases are designed and analyzed before manufacturing these products, this study result can be contributed to the strength durability.

• 한국환경과학회지
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• 제20권11호
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• pp.1373-1382
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• 2011

This research had been conducted from May to October 2007, studying 110 residents of G, Y, H industrial area in Jun-nam province. It is designed to understand the difference in levels of indoor, outdoor and personal exposure to VOCs(benzene, toluene, Ethylbenzene) and a health risk assessment was conducted to see if there was any fatal cause from carcinogenic or non - carcinogenic elements from a case group and a control group in all areas as well as each different area. In the case of benzene in the air, the geometric levels for the case group are indoor, outdoor and personal exposure; a higher than for the control group. As a results of the Monte - Carlo study about benzene, it shows that the case group's carcinogenicity is higher than that of the control group and it also shows that, on the CTE, RME condition and Monte - Carlo analysis, all subjects are seen to exceed the carcinogenicity tolerance $10^{-6}$ of US EPA. In the case of toluene, ethylbenzene on the CTE, RME condition and Monte - Carlo analysis, these do not exceed the non - carcinogenic standard of 1, but toluene in RME condition for both groups' personal exposure and the indoor and personal exposure of ethylbenzene in Monte - Carlo show that these seem to exceed the standard.

• 한국환경과학회지
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• 제25권2호
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• pp.311-322
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• 2016

This study reduced and built Street Canyons created by skyscrapers in order to verify effect of Street Canyons by green wall within the city centre and analysed influence factors on temperature reduction according to applicative types of green wall in the lab. Applicative types were divided into three types such as non- greening type(Case A), one-side greening type(Case B), both side greening type(Case C). The result of analysis of each types showed that average temperature of Case B and Case C is respectively $1.0^{\circ}C$ and $1.7^{\circ}C$ lower than Case A. The result of analysis of WBGT was that the highest temperature was given by Case A($40.2^{\circ}C$) and second one was from Case B($39.8^{\circ}C$) and third one was from ($39.1^{\circ}C$) and in UTCI Case A records the highest temperature of $34.7^{\circ}C$ and Case B provided the second highest temperature of $33.9^{\circ}C$ and Case B gave the lowest temperature of $32.7^{\circ}C$. In PMV the highest temperature of 2.65 was from Case B and second one of 2.61 was from Case A and third one of 2.54 was from Case C. Duncan analysis of each types based on solar radiation and thermal comfort generated that there was analytical significance between Case A and Case B and Case B in terms of each types of average temperature reduction. The significance of thermal comfort in WBGT, MRT, PMV showed non-significance but, In UTCI it was analysed that there was significance between Case C and Case A.