• Korean Journal of Remote Sensing
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• 제39권5_1호
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• pp.637-654
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• 2023

In recent years, the number of users has been increasing with the rapid development of earth observation satellites. In response, the Committee on Earth Observation Satellites (CEOS) has been striving to provide user-friendly satellite images by introducing the concept of Analysis Ready Data (ARD) and defining its requirements as CEOS ARD for Land (CARD4L). In ARD, a mask called an Unusable Data Mask (UDM), identifying unnecessary pixels for land analysis, should be provided with a satellite image. UDMs include clouds, cloud shadows, terrain shadows, etc. Terrain shadows are generated in mountainous terrain with large terrain relief, and these areas cause errors in analysis due to their low radiation intensity. previous research on terrain shadow detection focused on detecting terrain shadow pixels to correct terrain shadows. However, this should be replaced by the terrain correction method. Therefore, there is a need to expand the purpose of terrain shadow detection. In this study, to utilize CAS500-4 for forest and agriculture analysis, we extended the scope of the terrain shadow detection to shaded areas. This paper aims to analyze the potential for terrain shadow detection to make a terrain shadow mask for South and North Korea. To detect terrain shadows, we used a Hill-shade algorithm that utilizes the position of the sun and a surface's derivatives, such as slope and aspect. Using RapidEye images with a spatial resolution of 5 meters and Sentinel-2 images with a spatial resolution of 10 meters over the Korean Peninsula, the optimal threshold for shadow determination was confirmed by comparing them with the ground truth. The optimal threshold was used to perform terrain shadow detection, and the results were analyzed. As a qualitative result, it was confirmed that the shape was similar to the ground truth as a whole. In addition, it was confirmed that most of the F1 scores were between 0.8 and 0.94 for all images tested. Based on the results of this study, it was confirmed that automatic terrain shadow detection was well performed throughout the Korean Peninsula.

• Journal of Integrative Natural Science
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• 제9권2호
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• pp.94-102
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• 2016

The crystal structure of the potential active 6-ethoxy-3-phenyl-5a,9a-dihydro-3H-chromen[4,3-c][1,2]oxazole-3a(4H)-carbonitrile ($C_{19}H_{15}N_2O_3$) has been determined from single crystal X-ray diffraction technique. The title compound crystallizes in the monoclinic space group C2/c with unit cell dimension a= 29.3026(9) ${\AA}$, b= 6.7695(2) ${\AA}$ and c= 19.7597(6) ${\AA}$ [${\alpha}= 90^{\circ}$, ${\beta}= 125.709(10)^{\circ}$ and ${\gamma}= 90^{\circ}$]. Single crystals suitable for X-ray diffraction were obtained by slow evaporation method, the isoxazole and six membered pyran rings adopts envelope conformation. The crystal packing of the molecules is stabilized by the weak $C-H{\ldots}N$ hydrogen bond interaction.

• Journal of Integrative Natural Science
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• 제9권2호
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• pp.103-112
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• 2016

The crystal structure of the potential active Methyl 8-bromo-3-phenyl-5a,9a-dihydro-3H-chromen [4,3-c][1,2] isoxazole-3a(4H)-carboxylate ($C_{18}H_{15}BrNO_4$) has been determined from single crystal X-ray diffraction technique. The title compound crystallizes in the triclinic space group Pī with unit cell dimension a=8.3129 (3) ${\AA}$, b=9.5847 (4) ${\AA}$ and c=11.1463(4) ${\AA}$ [${\alpha}=98.457(3)^{\circ}$, ${\beta}=102.806(2)^{\circ}$ and ${\gamma}=105.033(5)^{\circ}$]. Single crystals suitable for X-ray diffraction were obtained by slow evaporation method, the isoxazole and six membered pyran rings adopts envelope conformation. In the crystal, molecules are linked via pairs of inter molecular $C-H{\ldots}O$ hydrogen bonds to form dimmers.

• The Bulletin of The Korean Astronomical Society
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• 제37권2호
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• pp.142.2-142.2
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• 2012

Hoffmeister(1943)에 의해 변광성으로 발견된 V345 Cas (2MASS J23083986+5406545, ${\alpha}$(2000.0)=23h08m39.86s & ${\delta}(2000.0)=+54^{\circ}06^{\prime}54.6^{\prime\prime}$)는 B 필터에서 13.1~14.2의 광도 변화를 보이는 것으로 알려진 별이다. 우리는 레몬산 천문대(LOAO)에서 2007년과 2008년에 걸쳐 총 22일간 V345 Cas의 BVRI CCD 측광관측을 수행하여, 처음으로 V345 Cas의 년도 별 전체 광도곡선을 완성하였다. 우리의 관측 자료와 Super WASP에서 공개한 자료를 이용하여 각각 7개의 극심시각을 산출하였다. 우리가 결정한 극심시각을 포함하여 여러 문헌에서 수집한 총 68개의 극심시각을 이용하여 V345 Cas의 주기 분석을 수행하였다. 그 결과, V345 Cas의 궤도주기는 포물선 모양의 영년변화와 함께 약 30년의 규칙적인 변화를 겪고 있음을 발견하였다. 규칙적인 변화를 제3천체에 의한 광시간 효과로 가정하여 관측된 극심시각에 잘 맞는 광시간 궤도 해를 산출한 결과, 영년주기가 증가하는 경우와 감소하는 경우에 대해, 각각 29.0년과 39.7년 주기를 갖는 두 개의 광시간 궤도 해가 가능하다. 이러한 모호성을 해결하기 위해서 앞으로의 극심시각 관측이 중요하다. 2007년과 2008년 BVRI 광도곡선들은 부극심을 기준으로 좌우가 거의 대칭이며, 1년 사이에 특기할 만한 광도변화를 보이지 않았다. 우리는 이 광도곡선들을 Wilson-Devinney 쌍성 모델을 이용하여 분석하여, V345 Cas의 측광학적 해를 처음으로 산출하였다. 우리가 구한 해에 의하면, 약 88도의 궤도경사각에 두 성분별의 질량비가 약 0.5인 V345 Cas는 질량과 표면 온도가 큰 주성과 로쉬 로브를 채우고 있는 반성으로 구성된 준 분리형 식쌍성계이다.

• The Korean Journal of Zoology
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• 제3권1호
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• pp.9-12
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• 1960

The present status of insecticide resistance of Korean mosquitoes is still unknown. The experiment cited below is a part of our series of resistance tests on Korean mosquitoes. The test was carried out during the summer of 1959 to ascertain the degree of resistance of Culex pipiens to insecticides currently used. Culex pipiens eggs were collected from ditches in Seoul City and reared in laboratory with media consisted of the following : Distrilled water 1.0 liter, Magnesium sulfate (MgSO$_4$.7$H_2O$) 1.0gram , Calcium sulfate (CasO$_4$.2$H_2O$) 0.5gram ; Sodium cholride 0.5 gram. A Sufficient amount of beer yeast was also used as a larvar food. Late third and early fourth instar larvae were selected for testing. The results are summarized in the following. THe LC-50 of Culex pipiens to insecticides were 0.061 ppm in p, p-DDT , 0.045 ppm in ${\gamma}$-BHC and0.029 ppm in malathion. Comparing these with LC-50 doses of Orlando laboratory strain, it can be pointed out that the present resistance of Seoul strain shows about a ten-fold increase in DDt, and a fourfold increase in ${\gamma}$-BHC . The resistance development of the Seoul strain has, however, not arisen so markedly as compared with data observed in other parts of Far Eastern areas received heavy insecticidal operations.

• Microbiology and Biotechnology Letters
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• 제49권4호
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• pp.594-602
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• 2021

The NLRP3 (nucleotide-binding domain, leucine-rich repeat family pyrin domain containing 3) inflammasome plays an important role in the initiation of inflammatory responses, through the recognition of pathogen-associated molecular patterns and tumor progression, including tumor growth and metastasis. In this study, we examined the effects of defective NLRP3 on the growth, migration, and invasiveness of hepatocellular carcinoma (HCC) SK-Hep1 cell. First, HCC SK-Hep1 cells were transfected with human NLRP3 targeting LentiCRISPRv2 vector using the CRISPR-Cas9 system, and NLRP3 deficiency was confirmed by RT-qPCR and western blotting. NLRP3 deficient SK-Hep1 cells showed delayed cell growth and decreased protein expression of PI3K, p-AKT, and pNF-κB when compared to NLRP3 complete SK-Hep1 cells. In addition, NLRP3 deficiency arrested the cell cycle at G1 phase through an increase in p21 and a reduction in CDK6. NLRP3 deficient SK-Hep1 cells also showed significantly delayed cell migration, invasion, and wound healing. The expression of epithelial-mesenchymal transition signaling molecules, such as N-cadherin and MMP-9, was found to be dramatically decreased in NLRP3 deficient SK-Hep1 cells compared to NLRP3 complete SK-Hep1 cells.

• Proceedings of the Optical Society of Korea Conference
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• 한국광학회 2000년도 하계학술발표회
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• pp.3-3
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• 2000

Adaptive Optical (AO) technology can compensate for wave-front errors in real-time to improve image and beam quality. The research and development on AO in China began in 1979. In 1980, the first laboratory on AO in China was established in Institute of Optics and Electronics (IOE), Chinese Academy of Sciences (CAS). Since then several AO systems have been built in this Laboratory. The 19-element system is the first AO system in the world ever used in inertial confinement fusion (ICF) facility in our knowledge. It corrects the static error of this large laser engineering. The 21-element system was firstly tested at the 1.2m telescope of Kunming Observatory in 1990 and then up-dated as an IR AO system installed at the 2.16m telescope of Beijing Observatory. The 37-element system was used with a turbulence cell in Laboratory on Atmospheric Optics in Hefei to conduct elementary research on Atmospheric Optics. The 61-element system for astronomical observation is newly developed. It has been successfully installed at the 1.2m telescope of Kunming Observatory and a laser guide star system will be integrated with the system. A compact AO system using our newly developed miniature DM for high resolution ophthalmic imaging of retina is also being built. The key elements of these AO systems, deformable mirrors and fast-steering mirrors, are all developed in this Laboratory. In this talk, the main configurations of these AO systems, some test results as well as the specifications of these active mirrors will be presented.

• Journal of Microbiology and Biotechnology
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• 제29권1호
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• pp.105-113
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• 2019

Although siderophore compounds are mainly biosynthesized as a response to iron deficiency in the environment, they also bind with other metals. A few studies have been conducted on the impact of heavy metals on the siderophore-mediated iron uptake by microbiome. Here, we investigated siderophore production by a variety of rhizosphere fungi under different concentrations of $Zn^{2+}$ ion. These strains were specifically isolated from the rhizosphere of Panax ginseng (Korean ginseng). The siderophore production of isolated fungi was investigated with chrome azurol S (CAS) assay liquid media amended with different concentrations of $Zn^{2+}$ (50 to $250{\mu}g/ml$). The percentage of siderophore units was quantified using the ultra-violet (UV) irradiation method. The results indicated that high concentrations of $Zn^{2+}$ ion increase the production of siderophore in iron-limited cultures. Maximum siderophore production by the fungal strains was detected at $Zn^{2+}$ ion concentration of $150{\mu}g/ml$ except for Mortierella sp., which had the highest siderophore production at $200{\mu}g/ml$. One potent siderophore-producing strain (Penicillium sp. JJHO) was strongly influenced by the presence of $Zn^{2+}$ ions and showed high identity to P. commune (100% using 18S-rRNA sequencing). The purified siderophores of the Penicillium sp. JJHO strain were chemically identified using UV, Fourier-transform infrared spectroscopy (FTIR), and matrix-assisted laser desorption/ionization time-of-flight mass spectrometer (MALDI-TOF-MS) spectra.

• The Bulletin of The Korean Astronomical Society
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• 제36권2호
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• pp.142.1-142.1
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• 2011

UBVI and $H{\alpha}$ CCD photometry of IC 1848, one of active star-forming regions in Cas OB6, is carried out as a part of Sejong Open cluster Survey (SOS) project. An OB association is an ideal laboratory for studying the triggered star formation and star formation history. Our purposes are to provide deep photometric data up to 21 mag in V and physical parameters of IC 1848. We classify 79 early-type stars and 186 pre-main sequence (PMS) stars as being the members of the cluster using photometric criteria. The IR excess emission PMS stars by Koenig et al. (2008) are also included as members of IC 1848. Total number of members is 414. We derive the interstellar reddening (=$0.659{\pm}0.058$ mag), reddening law ($R_V=4.0{\pm}0.1$), distance modulus ($V_0-M_V=12.0{\pm}0.1$ mag) using the early-type members of IC 1848. We also determine the age of the cluster ($3.5{\pm}1.5$ Myr) by placing the theoretical isochrones on the HR diagram.

• Korean Journal of Exercise Nutrition
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• 제23권2호
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• pp.1-6
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• 2019

[Purpose] Strenuous exercise often induces skeletal muscle damage, which results in impaired performance. Sphingolipid metabolism contributes to various cellular processes, including apoptosis, stress response, and inflammation. However, the relationship between exercise-induced muscle damage and ceramide (a key component of sphingolipid metabolism), is rarely studied. The present study aimed to explore the regulatory role of sphingolipid metabolism in exercise-induced muscle damage. [Methods] Mice were subjected to strenuous exercise by treadmill running with gradual increase in intensity. The blood and gastrocnemius muscles (white and red portion) were collected immediately after and 24 h post exercise. For 3 days, imipramine was intraperitoneally injected 1 h prior to treadmill running. [Results] Interleukin 6 (IL-6) and serum creatine kinase (CK) levels were enhanced immediately after and 24 h post exercise (relative to those of resting), respectively. Acidic sphingomyelinase (A-SMase) protein expression in gastrocnemius muscles was significantly augmented by exercise, unlike, serine palmitoyltransferase-1 (SPT-1) and neutral sphingomyelinase (N-SMase) expressions. Furthermore, imipramine (a selective A-SMase inhibitor) treatment reduced the exercise-induced CK and IL-6 elevations, along with a decrease in cleaved caspase-3 (Cas-3) of gastrocnemius muscles. [Conclusion] We found the crucial role of A-SMase in exercise-induced muscle damage.