• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.27 no.2
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• pp.148-154
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• 2017

This paper discussed design for resonance avoidance of sensor plates of loose-parts monitoring systems (LPMS) in nuclear power plants (NPP). An LPMS monitors impact of loose parts in primary loop of NPP by using accelerometers, which is mounted on sensor plates. Resonance of the plates may cause false alarms at frequencies over 10 kHz, which can be misunderstood as impact signals of loose parts with small mass and cause unnecessary response of NPP operators. Modal analysis was carried out for the existing sensor plate and design parameters affecting natural frequencies were chosen. Frequency response functions of plates were analyzed by changing the parameters and the optimized plate design for avoiding resonance was determined. Experiments was carried out for the plate specimen with improved design and verified the proposed approach and design.

• Journal of Pharmaceutical Investigation
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• v.29 no.1
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• pp.21-27
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• 1999

Semi-solid poly(ortho esters) (POE) were prepared to provide bioerodible carriers for sustained drug delivery systems of naloxone (NLX) in the treatment of narcotic addiction. As the POE have viscous behavior at room temperature, a significant advantage of this polymer is that it can be injected without any surgical intervention. The POE was synthesized by a transesterification reaction between 1,2,6-hexanetriol and trimethyl orthoacetate, and the structure of the polymer was confirmed by IR. The in vitro release of the drug from POE was studied. The release rate of NLX decreased with increasing intrinsic viscosities of the polymer. In vivo biocompatibility studies were carried out in rats with NLX loaded POE. Histopathological analysis showed that NLX implants are well-tolerated by rats when used subcutaneously. Pharmacokinetic studies of POE-NLX implants of two different viscosities were carried out in rabbits. In all cases, plasma concentrations of NLX were maintained over 1 ng/ml for at least 168 hours, but initial burst effect was observed. Mean residence time(MRT) was found to depend on the viscosity of the polymer.

• International Journal of Reliability and Applications
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• v.15 no.2
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• pp.125-150
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• 2014

Accelerated life tests (ALTs) are extensively used to determine the reliability of a product in a short period of time. Test units are subject to elevated stresses which yield quick failures. ALT can be carried out using constant-stress, step-stress, progressive-stress, cyclic-stress or random-stress loading and their various combinations. An ALT with linearly increasing stress is ramp-stress test. Much of the previous work on planning ALTs has focused on constant-stress, step-stress, ramp-stress schemes and their various combinations where the stress is generally increased. This paper presents an optimal design of ramp soak-stress ALT model which is based on the principle of Thermal cycling. Thermal cycling involves applying high and low temperatures repeatedly over time. The optimal plan consists in finding out relevant experimental variables, namely, stress rates and stress rate change points, by minimizing variance of reliability function with pre-specified mission time under normal operating conditions. The Burr type XII life distribution and time-censored data have been used for the purpose. Burr type XII life distribution has been found appropriate for accelerated life testing experiments. The method developed has been explained using a numerical example and sensitivity analysis carried out.

• Smart Structures and Systems
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• v.15 no.4
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• pp.931-947
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• 2015

This paper focuses on the design of an intelligent control system. The used techniques are based on Neuro Fuzzy approaches applied to a magnetorheological damper in order to reduce the vibrations over footbridges; it has been applied to the Science Museum Footbridge of Valladolid, particularly. A model of the footbridge and of the damper has been built using different simulation tools, and a successful comparison with the real footbridge and the real damper has been carried out. This simulated model has allowed the reproduction of the behaviour of the footbridge and damper when a pedestrian walks across the footbridge. Once it is determined that the simulation results are similar to real data, the control system is introduced into the model. In this sense, different strategies based on Neuro Fuzzy systems have been studied. In fact, an ANFIS (Artificial Neuro Fuzzy Inference System) method has also been used, in addition to an alternative Neuro Fuzzy approach. Several trials have been carried out, using both techniques, obtaining satisfactory results after using these techniques.

• Journal of Pharmaceutical Investigation
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• v.29 no.2
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• pp.93-98
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• 1999

Semi-solid poly(ortho esters) (POE) were prepared to provide bioerodible carriers for sustained drug delivery systems of nifedipine in the treatment of cardiovascular disease. As the POE has viscous behavior at room temperature, a significant advantage of this polymer is that it can be injected without any surgical intervention. The POE was synthesized by a transesterification reaction between 1,2,6-hexanetriol and trimethyl orthoacetate and the nifedipine release from POE was studied in vitro. The release rate of nifedipine decreased with increasing the amount of nifedipine and the diethanolamine dispersed in the polymer. But the excess amounts, above 3%, of diethanolamine retarded the release of nifedipine. In vivo biocompatibility studies were carried out in rats with nifedipine loaded POE. Histopathological analysis showed that nifedipine loaded POE implants were well-tolerated by rats when used subcutaneously. In case of the rats implanted POE containing diethanolamine, tissue necrosis and inflammation were occured. Pharmacokinetic studies of nifedipine loaded POE implants were carried out in rabbits. In all cases, plasma concentrations of nifedipine were maintained over 15 ng/ml for at least 360 hours and biological half $life(t_{1/2})$ and mean residence time(MRT) were increased by addition of diethanolamine.

• Wind and Structures
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• v.22 no.1
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• pp.65-87
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• 2016

The wind velocity profile over the height of a structure in high intensity wind (HIW) events, such as downbursts, differs from that associated with atmospheric boundary layer (ABL) winds. Current design codes for lattice transmission structures contain only limited advice on the treatment of HIW effects, and structural design is carried out using wind load profiles and response factors derived for ABL winds. The present study assesses the load-deformation curve (capacity curve) of a transmission tower under modeled downburst wind loading, and compares it with that obtained for an ABL wind loading profile. The analysis considers nonlinear inelastic response under simulated downburst wind fields. The capacity curve is represented using the relationship between the base shear and the maximum tip displacement. The results indicate that the capacity curve remains relatively consistent between different downburst scenarios and an ABL loading profile. The use of the capacity curve avoids the difficulty associated with defining a reference wind speed and corresponding wind profile that are adequate and applicable for downburst and ABL winds, thereby allowing a direct comparison of response under synoptic and downburst events. Uncertainty propagation analysis is carried out to evaluate the tower capacity by considering the uncertainty in material properties and geometric variables. The results indicated the coefficient of variation of the tower capacity is small compared to those associated with extreme wind speeds.

• Proceedings of the Korean Geotechical Society Conference
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• 2008.03a
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• pp.119-126
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• 2008

Ground stiffness(shear wave velocity) is one of the key parameters in geotechnical earthquake engineering. An In-situ seismic technique has its own advantages and disadvantages over the others in stiffness measurements. By combining the crosshole and seismic cone techniques and utilizing favourable features of bender elements, a new hybrid probe has been developed in order to enhance data quality and easiness of testing. The basic structure of the probe, called "MudFork", is a fork composed of two blades, on each of which source and receiver bender elements were mounted respectively. To evaluate the disturbance caused by the penetration of the probe, shear wave velocity measurements were carried out in the Kaolinite slurry in the laboratory. Finally, the probe was penetrated in coastal mud near Incheon, Korea, using SPT(standard penetration test)rods pushed with a routine boring machine and shear wave velocity measurements were carried out. The results were verified with data from laboratory and cone testing. The performance of the probe turns out to be excellent in terms of data quality and testing convenience.

• Proceedings of the Korean Geotechical Society Conference
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• 2004.03b
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• pp.930-937
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• 2004

In tunnel blasting, rock damage and overbreak at excavation limits are strongly related to stability of the tunnel and cost for rock support, and also affect to maintenance after tunnel construction. In this study, many field tests and measurements have been carried out in highway tunnels so that discordance between blast design and practical production blasting could be settled and actual methods of over break control could be proposed through the understanding of the problems in existing blasting patterns. Test blasting in tunnel was carried out many times in two tunnel sites. Also, long hole blasting longer than existing blasting pattern was executed for good grade of rock mass whose RMR value is more than 60. Using the results of test blasting, new standard blasting patterns for two lane tunnel were proposed. As a result of profile measurement after blasting, drilling is a major factor of overbreak. And then the methods for minimizing overbreak were adapted in new blasting patterns.

• Proceedings of the Korea Concrete Institute Conference
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• 2010.05a
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• pp.467-468
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• 2010

Over the past few decades, considerable numbers of studies on the durability of concrete have been carried out extensively. The majority of these researches have been performed on sound uncracked concrete, although most of in-situ concrete structures have more or less micro-cracks. It is only recent approach that the attention has shifted towards the influence of cracks and crack width on the penetration of chloride into concrete. The penetration of chlorides into concrete through the cracks can make a significant harmful effect on reinforcement corrosion. Author of this study examined the effect of cracks on chloride penetration by short term experiment. However, it is necessary to accomplish the effect by long term experiment to get reliable goal. In this study, the long term and short term experiments were carried out. This can be useful for establishing new species model of chloride penetration through cracks in concrete.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.3 s.174
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• pp.761-768
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• 2000

In order to investigate how the fatigue damage effects on the critical properties of superconductor, a fatigue test at room temperature and an Ic measurement test at 4.2K were carried out in this study, respectively, using a 9 strand Cu-Ni/NbTi/Cu composite cable. Through the fatigue test of a 9 strand Cu-NUNbTi/Cu composite cable, a conventional S-N curve was plotted even though there was a possibility of fretting among strands. It was found that the maximum stress corresponding to the inflection point on the S-N curve obtained was nearly the same value as the yielding strength of cable obtained from the static tensile test. However, the effect of cabling in multi-strands superconducting cable on the fatigue strength was not noticeable. The critical current(Ic) measurement was carried out at 4.2K in a NbTi strand out of the fatigued cable. It showed a degradation of lc at high stress amplitude regions over 380NTa, and the degradation became significant as the applied stress amplitude increased.