• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.57-60
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• 1995

The objective of this investigation is to understand the role of hemodynamics in the formation and development of atherosclerosis lesions in the human left coronary artery This study also aims to compare the blood flow characteristics of steady and physiological flows. Three dimensional, steady and physiological flows of blood in the left coronary artery are simulated using the Finite Volume Method. Apparent viscosity of blood is represented as a function of shear rate by the Carreau model. Distributions of velocity, pressure and shear stress in tile left coronary artery bifurcation are presented to compare tile steady and physiological flow characteristics.

• Korea-Australia Rheology Journal
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• v.18 no.3
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• pp.153-160
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• 2006

We analyzed the non-Newtonian and non-isothermal flow with Carreau-Yasuda viscosity model in co-rotating and counter-rotating twin screw extruder systems. The mixing performances with respect to the screw speed, the screw pitch, and the rotating direction have been investigated. The dynamics of mixing was studied numerically by tracking the motions of particles. The extent of mixing was characterized in terms of the deformation rate, the residence time distribution, and the average strain. The results showed that the high screw speed decreases the residence time but increases the deformation rate. Small screw pitch increases the residence time. It is concluded that the high screw speed increases the dispersive mixing performance, while the small screw pitch increases the distributive mixing performance. Co-rotating screw extruder has the better conveying performance and the distributive mixing performance than counter-rotating screw extruder with the same screw speed and pitch. Co-rotating screw extruder developed faster transport velocity and it is advantageous the flow characteristics to the mixing that transfers polymer melt from one barrel to the other barrel.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.16 no.1
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• pp.42-50
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• 2017

A cerebral aneurysm is a ballooning arising from a weakened area in the wall of a blood vessel in the brain. In this study, the flow analysis of the blood vessel, including the cerebral aneurysm and the stent, was conducted to investigate the effect of the stent shape on reduction of blood flowing into the cerebral aneurysm. We used the Carreau model to describe Non-Newtonian behaviors of blood flow. Two kinds of stents, which had different cross angles were modelled by the commercial CAD program and the geometries of those stents were reflected in the analysis domain of the blood vessel. From the results of the flow analysis, we found that the blood flowing into the cerebral aneurysm was decreased as the cross angle of the stent was decreased.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.20 no.5
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• pp.1603-1612
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• 1996

The pressure loss coefficient of Newtonian and non-Newtonian fluids such as water, aqueous solutions of Carbopol-934 and Separan AP-273 and blood in the stenotic tubes are determined experimentally and numerically. The numerical analyses for flows of non-Newtonian fluids in the stenotic tubes are conducted by the finite element method. The effect of the contraction ratio and the ratio of length to diameter on the pressure drop are investigated by the experiments and numerical analysis. The pressure loss coefficients are significantly dependent upon the Reynolds number in the laminar flow regime. As Reynolds number increases, the pressure loss coefficients of both Newtonian and non-Newtonian fluids decrease in the laminar flow regime. As the ratio of length to diameter increases the maximum pressure loss coefficient increases in the laminar flow regime for both Newtonian and non-Newtonian fluids. Newtonian fuid shows the highest values of pressure loss coefficient and blood the next, followed by Carbopol solution and Separan solution in order. Experimental results are used to verify the numerical analyses for flows of Newtonian and non-Newtonian fluids. Numerical results for the maximum pressure loss coefficient in the stenotic tubes are in fairly good agreement with the experimental results. The relative differences between the numerical and experimental results of the pressure loss coefficients in the laminar flow regime range from 0.5% to 14.8%.

• Journal of Chest Surgery
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• v.44 no.2
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• pp.89-98
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• 2011

Background: Although considerable efforts have been made to improve the graft patency in coronary artery bypass surgery, the role of biomechanical factors remains underrecognized. The aim of this study is to investigate the influences of geometric configurations of the bypass graft on hemodynamic characteristics in relation to anastomosis. Materials and Methods: The Numerical analysis focuses on understanding the flow patterns for different values of inlet and distal diameters and graft angles. The Blood flow field is treated as a two-dimensional incompressible laminar flow. A finite volume method is adopted for discretization of the governing equations. The Carreau model is employed as a constitutive equation for blood. In an attempt to obtain the optimal aorto-coronary bypass conditions, the blood flow characteristics are analyzed using in vitro models of the end-to-side anastomotic angles of $45^{\circ}$, $60^{\circ}$ and $90^{\circ}$. To find the optimal graft configurations, the mass flow rates at the outlets of the four models are compared quantitatively. Results: This study finds that Model 3, whose bypass diameter is the same as the inlet diameter of the stenosed coronary artery, delivers the largest amount of blood and the least pressure drop along the arteries. Conclusion: Biomechanical factors are speculated to contribute to the graft patency in coronary artery bypass grafting.

• Journal of Biomedical Engineering Research
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• v.23 no.4
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• pp.281-286
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• 2002

In this study, blood flow in a carotid artery supplying blood to the human's brain has been numerically simulated to find out how the blood flow affects the genesis and the growth of atherosclerosis and arterial thrombosis. Velocity Profiles and hemodynamic parameters have been investigated for the carotid arteries with three different stenoses under physiological flow condition. Blood has been treated as Newtonian and non-Newtonian fluid. To model the shear thinning properties of blood for non-Newtonian fluid, the Carreau-Yasuda model has been employed. The result shows that the wall shear stress(WSS) increases with the development of stenosis and that the wall shear stress in Newtonian fluid is highly evaluated compared with that in non-Newtonian Fluid. Oscillatory shear index has been employed to identify the time-averaged reattachment point and this point is located farther from the stenosis for Newtonian fluid than for non-Newtonian fluid The wall shear stress gradient(WSSG) along the wall has been estimated to be very high around the stenosis region when stenosis is developed much and the WSSG peak value of Newtonian fluid is higher than that of non-Newtonian fluid.